JPS5733595A - Purification of urokinase - Google Patents
Purification of urokinaseInfo
- Publication number
- JPS5733595A JPS5733595A JP10871480A JP10871480A JPS5733595A JP S5733595 A JPS5733595 A JP S5733595A JP 10871480 A JP10871480 A JP 10871480A JP 10871480 A JP10871480 A JP 10871480A JP S5733595 A JPS5733595 A JP S5733595A
- Authority
- JP
- Japan
- Prior art keywords
- solution
- adsorb
- ion
- urokinase
- exchanger
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Enzymes And Modification Thereof (AREA)
Abstract
PURPOSE: An ion-exchanger containing diethylaminoethyl groups is made to adsorb a quaternary ammonium salt solution and brought into contact with a crude urokinase solution to adsorb impurities, thus producing the titled substance of high purity rapidly and easily.
CONSTITUTION: An ion-exchanger containing diethylaminoethyl groups that is composed of a high polymeric polysaccharide such as diethylaminoethyl group-containing cellulose or crosslinked dextran is made to adsorb a quaternary ammonium salt solution. For example, a cationic surfactant such as stearyltrimethylammonium chloride or an amphoteric surfactant is used and the unadsorbed salt is removed with a buffer solution of pH5W8. Then, a crude urokinase solution is brought into contact with the resultant ion-exchanger to effect the adsorption of impurities and obtain the purified urokinase.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10871480A JPS5733595A (en) | 1980-08-07 | 1980-08-07 | Purification of urokinase |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10871480A JPS5733595A (en) | 1980-08-07 | 1980-08-07 | Purification of urokinase |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5733595A true JPS5733595A (en) | 1982-02-23 |
Family
ID=14491721
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10871480A Pending JPS5733595A (en) | 1980-08-07 | 1980-08-07 | Purification of urokinase |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5733595A (en) |
-
1980
- 1980-08-07 JP JP10871480A patent/JPS5733595A/en active Pending
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS52100500A (en) | Purification and concentration of aqueous stevioside extract | |
ES525361A0 (en) | PROCEDURE TO PREPARE A SAFE MEDICATION AGAINST HEPATITIS CONTAINING PROTEIN CALLED INACTIVATOR CL. | |
JPS5733595A (en) | Purification of urokinase | |
GB902639A (en) | Method of purification of streptokinase | |
JPS5517364A (en) | Purification of pancreatic kallikrein | |
HUT35471A (en) | Herbicide preparations containing antidote of n-/dichlor-acetyl/-n-substituted.glycine-n', n-disubstituted-amide-type, or containing agent and antidote, as well as process for the production of the antidote | |
JPS51126399A (en) | Purification of sodium hydroxide | |
JPS54101486A (en) | Purification of urokinase | |
JPS5599191A (en) | Purification of kallikrein in human urine | |
JPS5212984A (en) | Purification of urokinase | |
JPS52128294A (en) | Separation and purification of cephalosporins | |
JPS57150382A (en) | Purification of super oxide dismutase | |
JPS52797A (en) | Purification process of solution of sodium hypochlorite | |
JPS5513002A (en) | Preparation of urokinase | |
JPS57203015A (en) | Purifying method of human urinary callicrein | |
JPS5211359A (en) | Manufacturing process of spring washer and its washer | |
JPS55150900A (en) | Production of interferon | |
JPS51136784A (en) | Method f or preparing a polymer containing a a skelton of stabilizer in the molecule | |
JPS6485077A (en) | Purification of arginine residue-specific endopeptidase | |
JPS51117995A (en) | Hidrogen purifying process | |
JPS5581587A (en) | Purification of kallikrein | |
JPS5420191A (en) | Purification of urokinase | |
JPS5259081A (en) | Method of purifying liquid crystal | |
JPS55304A (en) | Purification of hbs antigen | |
JPS5264697A (en) | Process for treating single area |