JPS5581900A - Preparation of combined steroid hormone derivative- antitumor substance - Google Patents
Preparation of combined steroid hormone derivative- antitumor substanceInfo
- Publication number
- JPS5581900A JPS5581900A JP15484278A JP15484278A JPS5581900A JP S5581900 A JPS5581900 A JP S5581900A JP 15484278 A JP15484278 A JP 15484278A JP 15484278 A JP15484278 A JP 15484278A JP S5581900 A JPS5581900 A JP S5581900A
- Authority
- JP
- Japan
- Prior art keywords
- antitumor substance
- steroid hormone
- preparation
- antitumor
- substance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000126 substance Substances 0.000 title abstract 4
- 230000000259 anti-tumor effect Effects 0.000 title abstract 3
- 239000003270 steroid hormone Substances 0.000 title abstract 2
- 150000003431 steroids Chemical class 0.000 abstract 2
- QZLYKIGBANMMBK-UGCZWRCOSA-N 5α-Androstane Chemical compound C([C@@H]1CC2)CCC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CCC[C@@]2(C)CC1 QZLYKIGBANMMBK-UGCZWRCOSA-N 0.000 abstract 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- NQUXNVQKWZKBQI-VVSAWPALSA-N benzyl N-[(2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)-2-methyloxan-3-yl]carbamate Chemical compound C[C@@]1(O)[C@H](NC(=O)OCC2=CC=CC=C2)[C@@H](O)[C@H](O)[C@H](O1)CO NQUXNVQKWZKBQI-VVSAWPALSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- GRXPVLPQNMUNNX-MHJRRCNVSA-N estrane Chemical compound C1CC2CCCC[C@@H]2[C@@H]2[C@@H]1[C@@H]1CCC[C@@]1(C)CC2 GRXPVLPQNMUNNX-MHJRRCNVSA-N 0.000 abstract 1
- UACIBCPNAKBWHX-CTBOZYAPSA-N gonane Chemical compound C1CCC[C@@H]2[C@H]3CC[C@@H]4CCC[C@H]4[C@@H]3CCC21 UACIBCPNAKBWHX-CTBOZYAPSA-N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- GGCZERPQGJTIQP-UHFFFAOYSA-N sodium;9,10-dioxoanthracene-2-sulfonic acid Chemical compound [Na+].C1=CC=C2C(=O)C3=CC(S(=O)(=O)O)=CC=C3C(=O)C2=C1 GGCZERPQGJTIQP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15484278A JPS5581900A (en) | 1978-12-14 | 1978-12-14 | Preparation of combined steroid hormone derivative- antitumor substance |
| US06/062,819 US4260736A (en) | 1978-08-14 | 1979-08-01 | Steroid hormone-antitumor derivatives |
| DE2932606A DE2932606C2 (de) | 1978-08-14 | 1979-08-10 | Östradiol-Antitumorderivate |
| FR7920546A FR2433537A1 (fr) | 1978-08-14 | 1979-08-10 | Derives d'hormones steroides antitumoraux et leur procede de preparation |
| CA000333653A CA1120922A (en) | 1978-08-14 | 1979-08-13 | Steroid hormone antitumor derivatives |
| IT25084/79A IT1196399B (it) | 1978-08-14 | 1979-08-13 | Derivati antitumorali a base di ormone steroide |
| CH740179A CH642976A5 (de) | 1978-08-14 | 1979-08-13 | Verfahren zur herstellung von steroidhormon-antitumorderivaten. |
| GB7928321A GB2028336B (en) | 1978-08-14 | 1979-08-14 | Steroid hormone-antitumour drug conjugates |
| NL7906178A NL190747C (nl) | 1978-08-14 | 1979-08-14 | Werkwijze ter bereiding van een geneesmiddel met antitumorwerking en werkwijze ter bereiding van steroid-derivaten die geschikt zijn voor gebruik bij eerstgenoemde werkwijze. |
| US06/212,117 US4360663A (en) | 1978-08-14 | 1980-12-02 | Steroid hormone-antitumor derivatives |
| FR8101887A FR2476093A1 (fr) | 1978-08-14 | 1981-01-30 | Nouveaux composes 3-hydroxy ou 3-acyloxy 1,3,5(10)-estratriene-17b-oxycarbonylmethyle et leur application en therapeutique |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15484278A JPS5581900A (en) | 1978-12-14 | 1978-12-14 | Preparation of combined steroid hormone derivative- antitumor substance |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5581900A true JPS5581900A (en) | 1980-06-20 |
| JPS629119B2 JPS629119B2 (enrdf_load_html_response) | 1987-02-26 |
Family
ID=15593075
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP15484278A Granted JPS5581900A (en) | 1978-08-14 | 1978-12-14 | Preparation of combined steroid hormone derivative- antitumor substance |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5581900A (enrdf_load_html_response) |
-
1978
- 1978-12-14 JP JP15484278A patent/JPS5581900A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS629119B2 (enrdf_load_html_response) | 1987-02-26 |
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