JPS5579372A - Preparation of carbostyril derivative - Google Patents
Preparation of carbostyril derivativeInfo
- Publication number
- JPS5579372A JPS5579372A JP15288278A JP15288278A JPS5579372A JP S5579372 A JPS5579372 A JP S5579372A JP 15288278 A JP15288278 A JP 15288278A JP 15288278 A JP15288278 A JP 15288278A JP S5579372 A JPS5579372 A JP S5579372A
- Authority
- JP
- Japan
- Prior art keywords
- group
- formula
- alkyl
- carbostyril derivative
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical class C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 title abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 2
- VIZXQZKPQUQDTO-UHFFFAOYSA-N 3-prop-1-enoxy-1h-quinolin-2-one Chemical class C1=CC=C2NC(=O)C(OC=CC)=CC2=C1 VIZXQZKPQUQDTO-UHFFFAOYSA-N 0.000 abstract 1
- 102000004861 Phosphoric Diester Hydrolases Human genes 0.000 abstract 1
- 108090001050 Phosphoric Diester Hydrolases Proteins 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 125000002572 propoxy group Chemical group [*]OC([H])([H])C(C([H])([H])[H])([H])[H] 0.000 abstract 1
- 231100000397 ulcer Toxicity 0.000 abstract 1
Landscapes
- Quinoline Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15288278A JPS5579372A (en) | 1978-12-08 | 1978-12-08 | Preparation of carbostyril derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15288278A JPS5579372A (en) | 1978-12-08 | 1978-12-08 | Preparation of carbostyril derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5579372A true JPS5579372A (en) | 1980-06-14 |
| JPS6128669B2 JPS6128669B2 (enrdf_load_stackoverflow) | 1986-07-01 |
Family
ID=15550174
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP15288278A Granted JPS5579372A (en) | 1978-12-08 | 1978-12-08 | Preparation of carbostyril derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5579372A (enrdf_load_stackoverflow) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1989010919A1 (en) | 1988-05-02 | 1989-11-16 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
| US6221881B1 (en) * | 1996-11-01 | 2001-04-24 | Nitromed, Inc. | Nitrosated and nitrosylated phosphodiesterase inhibitor compounds, compositions and their uses |
| JP2015199748A (ja) * | 2009-08-21 | 2015-11-12 | 大塚製薬株式会社 | 窒素含有化合物及び医薬組成物 |
-
1978
- 1978-12-08 JP JP15288278A patent/JPS5579372A/ja active Granted
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1989010919A1 (en) | 1988-05-02 | 1989-11-16 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
| JPH0249768A (ja) * | 1988-05-02 | 1990-02-20 | Otsuka Pharmaceut Co Ltd | カルボスチリル誘導体 |
| US6221881B1 (en) * | 1996-11-01 | 2001-04-24 | Nitromed, Inc. | Nitrosated and nitrosylated phosphodiesterase inhibitor compounds, compositions and their uses |
| JP2015199748A (ja) * | 2009-08-21 | 2015-11-12 | 大塚製薬株式会社 | 窒素含有化合物及び医薬組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6128669B2 (enrdf_load_stackoverflow) | 1986-07-01 |
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