JPS5579370A - Carbostyril derivative - Google Patents
Carbostyril derivativeInfo
- Publication number
- JPS5579370A JPS5579370A JP15288078A JP15288078A JPS5579370A JP S5579370 A JPS5579370 A JP S5579370A JP 15288078 A JP15288078 A JP 15288078A JP 15288078 A JP15288078 A JP 15288078A JP S5579370 A JPS5579370 A JP S5579370A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- carbostyril
- derivative
- bond
- carbostyril derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical class C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 title abstract 3
- CCKIVNWOHGPHLM-UHFFFAOYSA-N 4-[(2-oxo-1h-quinolin-3-yl)oxy]butanoic acid Chemical class C1=CC=C2NC(=O)C(OCCCC(=O)O)=CC2=C1 CCKIVNWOHGPHLM-UHFFFAOYSA-N 0.000 abstract 1
- 102000004861 Phosphoric Diester Hydrolases Human genes 0.000 abstract 1
- 108090001050 Phosphoric Diester Hydrolases Proteins 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000001741 anti-phlogistic effect Effects 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- XHVDMLOJJHWEOO-UHFFFAOYSA-N n-cyclohexyl-n-(2-hydroxyethyl)-4-[(2-oxo-1h-quinolin-6-yl)oxy]butanamide Chemical compound C=1C=C2NC(=O)C=CC2=CC=1OCCCC(=O)N(CCO)C1CCCCC1 XHVDMLOJJHWEOO-UHFFFAOYSA-N 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 231100000397 ulcer Toxicity 0.000 abstract 1
Landscapes
- Quinoline Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15288078A JPS5579370A (en) | 1978-12-08 | 1978-12-08 | Carbostyril derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15288078A JPS5579370A (en) | 1978-12-08 | 1978-12-08 | Carbostyril derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5579370A true JPS5579370A (en) | 1980-06-14 |
| JPS6126905B2 JPS6126905B2 (enrdf_load_stackoverflow) | 1986-06-23 |
Family
ID=15550134
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP15288078A Granted JPS5579370A (en) | 1978-12-08 | 1978-12-08 | Carbostyril derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5579370A (enrdf_load_stackoverflow) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57175168A (en) * | 1981-04-17 | 1982-10-28 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
| JPS57183761A (en) * | 1981-04-30 | 1982-11-12 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
| WO1989010919A1 (en) | 1988-05-02 | 1989-11-16 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
| WO1993004042A1 (fr) * | 1991-08-23 | 1993-03-04 | Otsuka Pharmaceutical Co., Ltd. | Derive de carbostyrile et antiagregant plaquettaire |
-
1978
- 1978-12-08 JP JP15288078A patent/JPS5579370A/ja active Granted
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57175168A (en) * | 1981-04-17 | 1982-10-28 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
| JPS57183761A (en) * | 1981-04-30 | 1982-11-12 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
| WO1989010919A1 (en) | 1988-05-02 | 1989-11-16 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
| JPH0249768A (ja) * | 1988-05-02 | 1990-02-20 | Otsuka Pharmaceut Co Ltd | カルボスチリル誘導体 |
| WO1993004042A1 (fr) * | 1991-08-23 | 1993-03-04 | Otsuka Pharmaceutical Co., Ltd. | Derive de carbostyrile et antiagregant plaquettaire |
| US5506239A (en) * | 1991-08-23 | 1996-04-09 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivative and platelets aggregation inhibitory agent |
| US5658926A (en) * | 1991-08-23 | 1997-08-19 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivative and platelets aggregation inhibitory agent |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6126905B2 (enrdf_load_stackoverflow) | 1986-06-23 |
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