JPS5579353A - Preparation of (2s,3r)-3-amino-2-hydroxy-4- phenylbutanoylaminoacetic acid and its intermediate - Google Patents
Preparation of (2s,3r)-3-amino-2-hydroxy-4- phenylbutanoylaminoacetic acid and its intermediateInfo
- Publication number
- JPS5579353A JPS5579353A JP15315778A JP15315778A JPS5579353A JP S5579353 A JPS5579353 A JP S5579353A JP 15315778 A JP15315778 A JP 15315778A JP 15315778 A JP15315778 A JP 15315778A JP S5579353 A JPS5579353 A JP S5579353A
- Authority
- JP
- Japan
- Prior art keywords
- amino
- compounds
- formula
- acid
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- GAFNVJIFDNKAIU-KOLCDFICSA-N 2-[[(2s,3r)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]acetic acid Chemical compound OC(=O)CNC(=O)[C@@H](O)[C@H](N)CC1=CC=CC=C1 GAFNVJIFDNKAIU-KOLCDFICSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 7
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 4
- 150000002148 esters Chemical group 0.000 abstract 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 229960002449 glycine Drugs 0.000 abstract 2
- 235000013905 glycine and its sodium salt Nutrition 0.000 abstract 2
- 239000012190 activator Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 238000010531 catalytic reduction reaction Methods 0.000 abstract 1
- 125000000524 functional group Chemical group 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (31)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15315778A JPS5579353A (en) | 1978-12-13 | 1978-12-13 | Preparation of (2s,3r)-3-amino-2-hydroxy-4- phenylbutanoylaminoacetic acid and its intermediate |
NLAANVRAGE7908510,A NL188162C (nl) | 1978-11-25 | 1979-11-22 | Werkwijze voor het bereiden van een bestatinederivaat. |
AR278992A AR227636A1 (es) | 1978-11-25 | 1979-11-22 | Procedimiento para producir acido treo-3-amino-2-hidroxibutanoil aminoacetico intermediarios para prepararlo y procedimiento para preparar los intermediarios |
CS814806A CS221955B2 (en) | 1978-12-13 | 1979-11-22 | Method of making the threo-3-amino-2-hydroxybutane acids |
GB7940413A GB2037754B (en) | 1978-11-25 | 1979-11-22 | Threo - 3 -protected amino - 2 - hydroxy-4oxobutanoic acids or esters, their preparation and their use in the preparation of threo - 3 - amino - 2 - hydroxy-butanoylaminoacetic acids |
ES486572A ES486572A1 (es) | 1978-11-25 | 1979-11-22 | Procedimiento para la fabricacion de acidos treo-3-amino-2- hidroxibutanoil amonoaceticos. |
CS798051A CS221953B2 (en) | 1978-12-13 | 1979-11-22 | Method of making the threo-3-amino-2-hydroxybutanoylaminoocto acids |
AU53115/79A AU530362B2 (en) | 1978-11-25 | 1979-11-22 | Threo-3-amino-2-hydroxy-butanoyl-aminoacetic acids |
GB8200496A GB2090595B (en) | 1978-11-25 | 1979-11-22 | Threo-3-amino-2-hydroxybutanoylacetice acid derivatives |
CA000340428A CA1182125A (en) | 1978-11-25 | 1979-11-22 | Process for producing threo-3-amino-2- hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them |
DE19792947140 DE2947140A1 (de) | 1978-11-25 | 1979-11-22 | Verfahren zur herstellung von threo-3-amino-2-hydroxybutanoyl- aminoessigsaeure |
CH6192/83A CH653669A5 (de) | 1978-11-25 | 1979-11-22 | Threo-3-geschuetzte amino-2-hydroxy-4-oxobutansaeure oder deren ester und verfahren zu ihrer herstellung. |
IT27487/79A IT1194593B (it) | 1978-11-25 | 1979-11-22 | Procedimento per la produzione di acidi treo-3-ammino-2-idrossibutanoilamminoacetici nonche' di loro intermedi |
CH5649/81A CH653687A5 (de) | 1978-11-25 | 1979-11-22 | Threo-3-amino-2-hydroxy-butanoylaminoessigsaeure-derivate. |
DK496379A DK162288C (da) | 1978-11-25 | 1979-11-22 | Fremgangsmaade til fremstilling af threo-3-amino-2-hydroxybutanoyl-aminoeddikesyrer |
SE7909655A SE452888B (sv) | 1978-11-25 | 1979-11-22 | Sett att framstella treo-3-amino-2-hydroxibutanoylaminoettiksyror |
FR7928830A FR2442227A1 (fr) | 1978-11-25 | 1979-11-22 | Procede de production d'acides threo-3-amino-2-hydroxybutanoylaminoacetiques |
DE2954076A DE2954076C2 (enrdf_load_stackoverflow) | 1978-11-25 | 1979-11-22 | |
CH10433/79A CH650265A5 (de) | 1978-11-25 | 1979-11-22 | Verfahren zur herstellung von substituierten threo-3-amino-2-hydroxybutanoylaminoessigsaeuren. |
HU79NI230A HU181920B (en) | 1978-12-13 | 1979-11-22 | Process for preparing n-threo-/3-amino-2-hydroxy-butanoyl/-amino-acetic acids |
US06/096,693 US4281180A (en) | 1978-11-25 | 1979-11-23 | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them |
FR8010563A FR2449078A1 (fr) | 1978-11-25 | 1980-05-12 | Procede de production d'acide threo-3-amino protege 2-hydroxy-4-oxobutanoique ou de ses esters et application a la production d'acide threo-3-amino-2-hydroxybutanoique |
US06/211,035 US4391986A (en) | 1978-11-25 | 1980-11-28 | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them |
FR8113611A FR2483409B1 (fr) | 1978-11-25 | 1981-07-10 | Derives de l'acide 3-amino-2-hydroxy butanoylaminoacetique et leur procede de preparation |
NL8104545A NL8104545A (nl) | 1978-11-25 | 1981-10-06 | "nieuwe threo-3-amino-2-hydroxybutanoylamino-azijnzuur- derivaten en daaruit verkregen geneesmiddelen. |
SE8106084A SE453748B (sv) | 1978-11-25 | 1981-10-14 | (2s,3r)-3-amino-2-hydroxi-4-(4-metoxifenyl)-butanoyl-(s)-leucin |
IT8125614A IT1211147B (it) | 1978-11-25 | 1981-12-15 | Acidi treo-3-ammino-2-idrossibutanoilammi no-acetici utili come farmaci. |
US06/336,492 US4453003A (en) | 1978-11-25 | 1981-12-31 | Process for producing threo-3-amino-2-hydroxy-butanoyl-aminoacetic acids as well as novel intermediates therefor and process for producing them |
CA000405157A CA1170667A (en) | 1978-11-25 | 1982-06-14 | Process for producing threo-3-amino-2-hydroxybutanoyl- aminoacetic acids, as well as novel intermediates therefor and process for producing them |
CA000410051A CA1167464A (en) | 1978-11-25 | 1982-08-24 | Process for producing threo-3-amino-2-hydroxybutanoyl- aminoacetic acids, as well as novel intermediates therefor and process for producing them |
SE8403931A SE466200B (sv) | 1978-11-25 | 1984-07-31 | Treo-3-skyddad amino-2-hydroxi-4-oxosmoersyra eller dess ester samt ett saett foer framstaellning daerav |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15315778A JPS5579353A (en) | 1978-12-13 | 1978-12-13 | Preparation of (2s,3r)-3-amino-2-hydroxy-4- phenylbutanoylaminoacetic acid and its intermediate |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP26930585A Division JPS61178955A (ja) | 1985-12-02 | 1985-12-02 | スレオ−3−アミノ−2−ヒドロキシ−4−フエニル酪酸の製造法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5579353A true JPS5579353A (en) | 1980-06-14 |
JPS6121466B2 JPS6121466B2 (enrdf_load_stackoverflow) | 1986-05-27 |
Family
ID=15556269
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15315778A Granted JPS5579353A (en) | 1978-11-25 | 1978-12-13 | Preparation of (2s,3r)-3-amino-2-hydroxy-4- phenylbutanoylaminoacetic acid and its intermediate |
Country Status (3)
Country | Link |
---|---|
JP (1) | JPS5579353A (enrdf_load_stackoverflow) |
CS (2) | CS221953B2 (enrdf_load_stackoverflow) |
HU (1) | HU181920B (enrdf_load_stackoverflow) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2009513503A (ja) * | 2003-07-08 | 2009-04-02 | ユニリーバー・ナームローゼ・ベンノートシヤープ | 化粧有効成分の製造方法 |
-
1978
- 1978-12-13 JP JP15315778A patent/JPS5579353A/ja active Granted
-
1979
- 1979-11-22 HU HU79NI230A patent/HU181920B/hu not_active IP Right Cessation
- 1979-11-22 CS CS798051A patent/CS221953B2/cs unknown
- 1979-11-22 CS CS814806A patent/CS221955B2/cs unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2009513503A (ja) * | 2003-07-08 | 2009-04-02 | ユニリーバー・ナームローゼ・ベンノートシヤープ | 化粧有効成分の製造方法 |
Also Published As
Publication number | Publication date |
---|---|
CS221953B2 (en) | 1983-04-29 |
HU181920B (en) | 1983-11-28 |
CS221955B2 (en) | 1983-04-29 |
JPS6121466B2 (enrdf_load_stackoverflow) | 1986-05-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS5576829A (en) | Beta,gamma-dihydropolyprenyl alcohol and hypotensive agent made from it | |
JPS5798270A (en) | 1,2-disubstituted-4-chloroimidazole-5-acetic acid derivative | |
JPS5579353A (en) | Preparation of (2s,3r)-3-amino-2-hydroxy-4- phenylbutanoylaminoacetic acid and its intermediate | |
JPS57146786A (en) | Optically active borane compound and preparation of optically active compound using the same | |
JPS54118404A (en) | Composition for removing oily film from windshield of vehicle | |
JPS57203049A (en) | Preparation of amide derivative | |
JPS57192340A (en) | Isoprenylamine derivative | |
JPS53108933A (en) | Production of amidinoformic acid derivative | |
JPS54103846A (en) | Production of cyclohexenecarboxylic acid derivative, intermediate for anti-allergic drug and surfactant | |
JPS5242815A (en) | Process for preparation of carboxylic acid esters | |
JPS5412369A (en) | Preparation of thienylacetic acid | |
JPS5217447A (en) | Process for preparation of trans-4- aminomethylcyclohexane-carboxylic acid ester | |
JPS5699480A (en) | Preparation of pyridopyrimidine derivative | |
JPS57179175A (en) | Preparation of 2-benzothiazolinone derivative or salt thereof | |
JPS54138575A (en) | Preparation of isoquinoline alcohols | |
JPS54106421A (en) | Preparation of carboxylic acid derivative | |
JPS5439077A (en) | Preparation of 5-substd picolinic acids | |
JPS53119819A (en) | Substituted iso-valerianic acid and its ester | |
JPS57116057A (en) | Preparation of 2-benzothiazolinone derivative or salt thereof | |
JPS5653680A (en) | Preparation of 1-(5'-oxohexyl)-theobromine | |
JPS56138142A (en) | Preparation of acrylic acid ester or methacrylic acid ester | |
JPS5551063A (en) | Preparation of n-ethyl-2-(2'-methoxy-5'-sulfamoylbenzamido-methyl)-pyrrolidine | |
JPS5587770A (en) | Preparation of 2-(p-isobutylphenyl)propionic acid 2-pyridinemethyl ester | |
JPS5572151A (en) | Threo-(2rs)-3-amino-2-hydroxy-4-oxo-4-phenylbutyric acid, its ester, and their preparation | |
JPS54112881A (en) | Preparation of 2-mercaptopyrimidine hydrochloride |