JPS5572111A - Colloidal aqueous composition and its manufacture - Google Patents

Colloidal aqueous composition and its manufacture

Info

Publication number
JPS5572111A
JPS5572111A JP14903879A JP14903879A JPS5572111A JP S5572111 A JPS5572111 A JP S5572111A JP 14903879 A JP14903879 A JP 14903879A JP 14903879 A JP14903879 A JP 14903879A JP S5572111 A JPS5572111 A JP S5572111A
Authority
JP
Japan
Prior art keywords
manufacture
aqueous composition
colloidal aqueous
colloidal
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP14903879A
Other languages
English (en)
Other versions
JPH0122243B2 (ja
Inventor
Shiyumitsuto Deiitaa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of JPS5572111A publication Critical patent/JPS5572111A/ja
Publication of JPH0122243B2 publication Critical patent/JPH0122243B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP14903879A 1978-11-21 1979-11-19 Colloidal aqueous composition and its manufacture Granted JPS5572111A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1192178 1978-11-21

Publications (2)

Publication Number Publication Date
JPS5572111A true JPS5572111A (en) 1980-05-30
JPH0122243B2 JPH0122243B2 (ja) 1989-04-25

Family

ID=4378189

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14903879A Granted JPS5572111A (en) 1978-11-21 1979-11-19 Colloidal aqueous composition and its manufacture

Country Status (22)

Country Link
US (1) US4271196A (ja)
EP (1) EP0011745B1 (ja)
JP (1) JPS5572111A (ja)
KR (1) KR850000584B1 (ja)
AR (1) AR225294A1 (ja)
AT (1) ATE501T1 (ja)
AU (1) AU529061B2 (ja)
CA (1) CA1136988A (ja)
DE (1) DE2961718D1 (ja)
DK (1) DK494079A (ja)
ES (1) ES486157A0 (ja)
FI (1) FI793461A (ja)
GR (1) GR73668B (ja)
HU (1) HU180792B (ja)
IE (1) IE48659B1 (ja)
IL (1) IL58723A (ja)
MC (1) MC1297A1 (ja)
NO (1) NO793759L (ja)
NZ (1) NZ192118A (ja)
PH (1) PH15561A (ja)
PT (1) PT70478A (ja)
ZA (1) ZA796116B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005516945A (ja) * 2001-12-21 2005-06-09 アベンティス・ファーマ・ソシエテ・アノニム アゼチジン誘導体に基づく医薬組成物

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2952115C2 (de) * 1979-12-22 1982-05-06 A. Nattermann & Cie GmbH, 5000 Köln Rosmarinsäure-Phospholipid-Komplex
US4374082A (en) * 1981-08-18 1983-02-15 Richard Hochschild Method for making a pharmaceutical and/or nutritional dosage form
US4457918A (en) * 1982-05-12 1984-07-03 The General Hospital Corporation Glycosides of vitamins A, E and K
CA1237670A (en) * 1983-05-26 1988-06-07 Andrew S. Janoff Drug preparations of reduced toxicity
US5059591B1 (en) * 1983-05-26 2000-04-25 Liposome Co Inc Drug preparations of reduced toxicity
US4622219A (en) * 1983-06-17 1986-11-11 Haynes Duncan H Method of inducing local anesthesia using microdroplets of a general anesthetic
JPS60208910A (ja) * 1984-03-31 1985-10-21 Green Cross Corp:The 水難溶性薬物・リン脂質複合体の製造方法
US5231112A (en) 1984-04-12 1993-07-27 The Liposome Company, Inc. Compositions containing tris salt of cholesterol hemisuccinate and antifungal
US4721612A (en) * 1984-04-12 1988-01-26 The Liposome Company, Inc. Steroidal liposomes
US4891208A (en) * 1985-04-10 1990-01-02 The Liposome Company, Inc. Steroidal liposomes
PT78628B (en) * 1984-05-02 1986-06-18 Liposome Co Inc Pharmaceutical composition with reduced toxicity
US5023271A (en) * 1985-08-13 1991-06-11 California Biotechnology Inc. Pharmaceutical microemulsions
US4861580A (en) * 1985-10-15 1989-08-29 The Liposome Company, Inc. Composition using salt form of organic acid derivative of alpha-tocopheral
US5041278A (en) * 1985-10-15 1991-08-20 The Liposome Company, Inc. Alpha tocopherol-based vesicles
CA1319886C (en) * 1987-02-03 1993-07-06 Alberto Ferro Mixed micelle solutions
IT1269569B (it) * 1994-04-22 1997-04-08 Ugo Citernesi Procedimento per la preparazione di complessi fra fosfolipidi e principi attivi utili per la produzione di liposomi e principi attivi e liposomi ottenuti con il procedimento
EP0682943B1 (de) * 1994-05-20 2003-08-20 GESELLSCHAFT FÜR MEDIZINISCHE FORSCHUNG UND WEITERBILDUNG e.V. GMF Lormetazepamhaltige Öl-in-Wasser-Emulsion
JP2740153B2 (ja) * 1995-03-07 1998-04-15 エフ・ホフマン−ラ ロシユ アーゲー 混合ミセル
AU709262B2 (en) * 1995-10-17 1999-08-26 Board Of Regents, The University Of Texas System Insoluble drug delivery
US6465016B2 (en) 1996-08-22 2002-10-15 Research Triangle Pharmaceuticals Cyclosporiine particles
US7255877B2 (en) * 1996-08-22 2007-08-14 Jagotec Ag Fenofibrate microparticles
AU762246B2 (en) * 1998-02-11 2003-06-19 Rtp Pharma Corporation Method and composition for treatment of inflammatory conditions
US6979456B1 (en) 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
CA2333648C (en) 1998-05-29 2008-10-21 Rtp Pharma Inc. Thermoprotected microparticle compositions and process for terminal steam sterilization thereof
IL141095A0 (en) 1998-08-19 2002-02-10 Rtp Pharma Inc Injectable aqueous dispersions of propofol
WO2000030616A1 (en) 1998-11-20 2000-06-02 Rtp Pharma Inc. Dispersible phospholipid stabilized microparticles
US6447806B1 (en) 1999-02-25 2002-09-10 Novartis Ag Pharmaceutical compositions comprised of stabilized peptide particles
DE60020382T2 (de) * 1999-09-21 2006-01-26 Skyepharma Canada Inc., Verdun Oberflächenmodifizierte teilchenförmige zusammensetzungen biologisch aktiver stoffe
ES2469642T3 (es) 2000-04-20 2014-06-18 Jagotec Ag Procedimiento mejorado para partículas de fármaco insoluble en agua
JP4969761B2 (ja) 2000-08-31 2012-07-04 オバン・エナジー・リミテッド 所望粒度を持つ固体基材の小粒子および第一材料の小粒状物を含む相乗作用性混合物を製造する方法
US8586094B2 (en) * 2000-09-20 2013-11-19 Jagotec Ag Coated tablets
CA2423336C (en) * 2000-09-20 2011-03-08 Rtp Pharma Inc. Stabilised fibrate microparticles
ES2284646T3 (es) * 2001-02-22 2007-11-16 Jagotec Ag Combinaciones de estatina-fibrato con efectos secundarios en ayunas-alimentado reducidos.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU28584A1 (ja) *
LU29060A1 (ja) *
FR2102537A5 (ja) * 1970-08-07 1972-04-07 Ugine Kuhlmann
FR2270887A1 (en) * 1974-05-16 1975-12-12 Chabrier De Lassauniere Pierre Prepn of lecithins and glycol-lecithins - by reaction of trimethylamine with 2-substd-2-oxo-1,3,2-dioxaphospholans
SE442014B (sv) * 1976-10-12 1985-11-25 Barry D Sears Syntetisk fosfatidyl-kvarter ammoniumforening till anvendning for solubilisering eller emulgering av vattenolosliga foreningar

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005516945A (ja) * 2001-12-21 2005-06-09 アベンティス・ファーマ・ソシエテ・アノニム アゼチジン誘導体に基づく医薬組成物

Also Published As

Publication number Publication date
KR850000584B1 (ko) 1985-04-30
IE48659B1 (en) 1985-04-03
US4271196A (en) 1981-06-02
IE792216L (en) 1980-05-21
CA1136988A (en) 1982-12-07
AR225294A1 (es) 1982-03-15
MC1297A1 (fr) 1980-10-03
FI793461A (fi) 1980-05-22
HU180792B (en) 1983-04-29
EP0011745B1 (de) 1981-12-30
ES8101855A1 (es) 1981-01-16
PT70478A (en) 1979-12-01
IL58723A0 (en) 1980-02-29
ATE501T1 (de) 1982-01-15
ES486157A0 (es) 1981-01-16
DK494079A (da) 1980-05-22
JPH0122243B2 (ja) 1989-04-25
NO793759L (no) 1980-05-22
EP0011745A1 (de) 1980-06-11
ZA796116B (en) 1980-11-26
PH15561A (en) 1983-02-11
AU5282479A (en) 1980-05-29
IL58723A (en) 1982-11-30
NZ192118A (en) 1981-12-15
GR73668B (ja) 1984-03-28
AU529061B2 (en) 1983-05-26
DE2961718D1 (en) 1982-02-18

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