ES8101855A1 - Un procedimiento para la preparacion de una composicion co- loidal lipidica de dihexanoil-lecitina - Google Patents

Un procedimiento para la preparacion de una composicion co- loidal lipidica de dihexanoil-lecitina

Info

Publication number
ES8101855A1
ES8101855A1 ES486157A ES486157A ES8101855A1 ES 8101855 A1 ES8101855 A1 ES 8101855A1 ES 486157 A ES486157 A ES 486157A ES 486157 A ES486157 A ES 486157A ES 8101855 A1 ES8101855 A1 ES 8101855A1
Authority
ES
Spain
Prior art keywords
colloidal aqueous
pharmacy
preparation
aqueous formulation
medicaments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES486157A
Other languages
English (en)
Other versions
ES486157A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES486157A0 publication Critical patent/ES486157A0/es
Publication of ES8101855A1 publication Critical patent/ES8101855A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE UNA COMPOSICION COLOIDAL LIPIDICA DE DIHEXANOIL-LECITINA. CONSTA DEL TRATAMIENTO DE UNA DIHEXANOIL-LECITINA CON UN LIPIDO NO HEMOLITICO Y EN LA OBTENCION, CON UN PRODUCTO ASI FORMADO, DE UNA DISPERSION ACUOSA COLOIDAL. TAMBIEN PUEDE EMPLEARSE UN DISOLVENTE ORGANICO, BAJO AGITACION Y APLICANDO CALOR; A CONTINUACION SE EVAPORA EL DISOLVENTE Y SE DISPERSA EL PRODUCTO RESTANTE EN LA CANTIDAD ADECUADA DE AGUA. LA COMPOSICION OBTENIDA, EN CUALQUIER CASO, PUEDE INCORPORAR, OPCIONALMENTE, UNA O MAS SUSTANCIAS ACTIVAS LIGERAMENTE SOLUBLES O INSOLUBLES EN AGUA Y, EN OCASIONES, UNA O MAS SUSTANCIAS FARMACEUTICAMENTE ACTIVAS SOLUBLES EN AGUA Y/O SUSTANCIAS FARMACEUTICAS COADYUVANTES.
ES486157A 1978-11-21 1979-11-20 Un procedimiento para la preparacion de una composicion co- loidal lipidica de dihexanoil-lecitina Expired ES8101855A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1192178 1978-11-21

Publications (2)

Publication Number Publication Date
ES486157A0 ES486157A0 (es) 1981-01-16
ES8101855A1 true ES8101855A1 (es) 1981-01-16

Family

ID=4378189

Family Applications (1)

Application Number Title Priority Date Filing Date
ES486157A Expired ES8101855A1 (es) 1978-11-21 1979-11-20 Un procedimiento para la preparacion de una composicion co- loidal lipidica de dihexanoil-lecitina

Country Status (22)

Country Link
US (1) US4271196A (es)
EP (1) EP0011745B1 (es)
JP (1) JPS5572111A (es)
KR (1) KR850000584B1 (es)
AR (1) AR225294A1 (es)
AT (1) ATE501T1 (es)
AU (1) AU529061B2 (es)
CA (1) CA1136988A (es)
DE (1) DE2961718D1 (es)
DK (1) DK494079A (es)
ES (1) ES8101855A1 (es)
FI (1) FI793461A (es)
GR (1) GR73668B (es)
HU (1) HU180792B (es)
IE (1) IE48659B1 (es)
IL (1) IL58723A (es)
MC (1) MC1297A1 (es)
NO (1) NO793759L (es)
NZ (1) NZ192118A (es)
PH (1) PH15561A (es)
PT (1) PT70478A (es)
ZA (1) ZA796116B (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2952115C2 (de) * 1979-12-22 1982-05-06 A. Nattermann & Cie GmbH, 5000 Köln Rosmarinsäure-Phospholipid-Komplex
US4374082A (en) * 1981-08-18 1983-02-15 Richard Hochschild Method for making a pharmaceutical and/or nutritional dosage form
US4457918A (en) * 1982-05-12 1984-07-03 The General Hospital Corporation Glycosides of vitamins A, E and K
US5059591B1 (en) * 1983-05-26 2000-04-25 Liposome Co Inc Drug preparations of reduced toxicity
CA1237670A (en) * 1983-05-26 1988-06-07 Andrew S. Janoff Drug preparations of reduced toxicity
US4622219A (en) * 1983-06-17 1986-11-11 Haynes Duncan H Method of inducing local anesthesia using microdroplets of a general anesthetic
JPS60208910A (ja) * 1984-03-31 1985-10-21 Green Cross Corp:The 水難溶性薬物・リン脂質複合体の製造方法
US4891208A (en) * 1985-04-10 1990-01-02 The Liposome Company, Inc. Steroidal liposomes
US4721612A (en) * 1984-04-12 1988-01-26 The Liposome Company, Inc. Steroidal liposomes
US5231112A (en) 1984-04-12 1993-07-27 The Liposome Company, Inc. Compositions containing tris salt of cholesterol hemisuccinate and antifungal
PT78628B (en) * 1984-05-02 1986-06-18 Liposome Co Inc Pharmaceutical composition with reduced toxicity
US5023271A (en) * 1985-08-13 1991-06-11 California Biotechnology Inc. Pharmaceutical microemulsions
US5041278A (en) * 1985-10-15 1991-08-20 The Liposome Company, Inc. Alpha tocopherol-based vesicles
US4861580A (en) * 1985-10-15 1989-08-29 The Liposome Company, Inc. Composition using salt form of organic acid derivative of alpha-tocopheral
CA1319886C (en) * 1987-02-03 1993-07-06 Alberto Ferro Mixed micelle solutions
IT1269569B (it) * 1994-04-22 1997-04-08 Ugo Citernesi Procedimento per la preparazione di complessi fra fosfolipidi e principi attivi utili per la produzione di liposomi e principi attivi e liposomi ottenuti con il procedimento
EP0682943B1 (de) * 1994-05-20 2003-08-20 GESELLSCHAFT FÜR MEDIZINISCHE FORSCHUNG UND WEITERBILDUNG e.V. GMF Lormetazepamhaltige Öl-in-Wasser-Emulsion
JP2740153B2 (ja) * 1995-03-07 1998-04-15 エフ・ホフマン−ラ ロシユ アーゲー 混合ミセル
CA2234957C (en) 1995-10-17 2006-12-19 Inge B. Henriksen Insoluble drug delivery
US7255877B2 (en) * 1996-08-22 2007-08-14 Jagotec Ag Fenofibrate microparticles
US6465016B2 (en) 1996-08-22 2002-10-15 Research Triangle Pharmaceuticals Cyclosporiine particles
IL137734A0 (en) * 1998-02-11 2001-10-31 Res Triangle Pharm Ltd Method and composition for treatment of inflammatory conditions
US6979456B1 (en) 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
AU764001B2 (en) 1998-05-29 2003-08-07 Skyepharma Canada Inc. Thermoprotected microparticle compositions and process for terminal steam sterilization thereof
JP4198318B2 (ja) 1998-08-19 2008-12-17 ヤーゴテック アクチェンゲゼルシャフト プロポフォールの注射可能水性分散物
CA2349203C (en) 1998-11-20 2013-05-21 Rtp Pharma Inc. Dispersible phospholipid stabilized microparticles
US6447806B1 (en) 1999-02-25 2002-09-10 Novartis Ag Pharmaceutical compositions comprised of stabilized peptide particles
CN1174741C (zh) * 1999-09-21 2004-11-10 Rtp药品公司 生物活性物质的表面改性微粒组合物
EP1276465B1 (en) 2000-04-20 2014-03-12 Jagotec AG Improved water-insoluble drug particle process
ATE424811T1 (de) 2000-08-31 2009-03-15 Jagotec Ag Gemahlene partikel
US8586094B2 (en) * 2000-09-20 2013-11-19 Jagotec Ag Coated tablets
AU2001255515A1 (en) * 2000-09-20 2002-04-02 Skyepharma Canada Inc. Stabilised fibrate microparticles
JP2004523552A (ja) * 2001-02-22 2004-08-05 スカイファーマ・カナダ・インコーポレーテッド 低減した摂食−絶食効果を伴うフィブラート−スタチンの組合わせ
FR2833842B1 (fr) * 2001-12-21 2004-02-13 Aventis Pharma Sa Compositions pharmaceutiques a base de derives d'azetidine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU29060A1 (es) *
LU28584A1 (es) *
FR2102537A5 (es) * 1970-08-07 1972-04-07 Ugine Kuhlmann
FR2270887A1 (en) * 1974-05-16 1975-12-12 Chabrier De Lassauniere Pierre Prepn of lecithins and glycol-lecithins - by reaction of trimethylamine with 2-substd-2-oxo-1,3,2-dioxaphospholans
SE442014B (sv) * 1976-10-12 1985-11-25 Barry D Sears Syntetisk fosfatidyl-kvarter ammoniumforening till anvendning for solubilisering eller emulgering av vattenolosliga foreningar

Also Published As

Publication number Publication date
CA1136988A (en) 1982-12-07
ATE501T1 (de) 1982-01-15
ES486157A0 (es) 1981-01-16
ZA796116B (en) 1980-11-26
DE2961718D1 (en) 1982-02-18
FI793461A (fi) 1980-05-22
JPH0122243B2 (es) 1989-04-25
NO793759L (no) 1980-05-22
US4271196A (en) 1981-06-02
GR73668B (es) 1984-03-28
AU529061B2 (en) 1983-05-26
IE792216L (en) 1980-05-21
HU180792B (en) 1983-04-29
EP0011745A1 (de) 1980-06-11
NZ192118A (en) 1981-12-15
DK494079A (da) 1980-05-22
AR225294A1 (es) 1982-03-15
IL58723A (en) 1982-11-30
MC1297A1 (fr) 1980-10-03
PT70478A (en) 1979-12-01
AU5282479A (en) 1980-05-29
KR850000584B1 (ko) 1985-04-30
EP0011745B1 (de) 1981-12-30
IL58723A0 (en) 1980-02-29
JPS5572111A (en) 1980-05-30
IE48659B1 (en) 1985-04-03
PH15561A (en) 1983-02-11

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