ES8101855A1 - Un procedimiento para la preparacion de una composicion co- loidal lipidica de dihexanoil-lecitina - Google Patents
Un procedimiento para la preparacion de una composicion co- loidal lipidica de dihexanoil-lecitinaInfo
- Publication number
- ES8101855A1 ES8101855A1 ES486157A ES486157A ES8101855A1 ES 8101855 A1 ES8101855 A1 ES 8101855A1 ES 486157 A ES486157 A ES 486157A ES 486157 A ES486157 A ES 486157A ES 8101855 A1 ES8101855 A1 ES 8101855A1
- Authority
- ES
- Spain
- Prior art keywords
- colloidal aqueous
- pharmacy
- preparation
- aqueous formulation
- medicaments
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE UNA COMPOSICION COLOIDAL LIPIDICA DE DIHEXANOIL-LECITINA. CONSTA DEL TRATAMIENTO DE UNA DIHEXANOIL-LECITINA CON UN LIPIDO NO HEMOLITICO Y EN LA OBTENCION, CON UN PRODUCTO ASI FORMADO, DE UNA DISPERSION ACUOSA COLOIDAL. TAMBIEN PUEDE EMPLEARSE UN DISOLVENTE ORGANICO, BAJO AGITACION Y APLICANDO CALOR; A CONTINUACION SE EVAPORA EL DISOLVENTE Y SE DISPERSA EL PRODUCTO RESTANTE EN LA CANTIDAD ADECUADA DE AGUA. LA COMPOSICION OBTENIDA, EN CUALQUIER CASO, PUEDE INCORPORAR, OPCIONALMENTE, UNA O MAS SUSTANCIAS ACTIVAS LIGERAMENTE SOLUBLES O INSOLUBLES EN AGUA Y, EN OCASIONES, UNA O MAS SUSTANCIAS FARMACEUTICAMENTE ACTIVAS SOLUBLES EN AGUA Y/O SUSTANCIAS FARMACEUTICAS COADYUVANTES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1192178 | 1978-11-21 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES486157A0 ES486157A0 (es) | 1981-01-16 |
ES8101855A1 true ES8101855A1 (es) | 1981-01-16 |
Family
ID=4378189
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES486157A Expired ES8101855A1 (es) | 1978-11-21 | 1979-11-20 | Un procedimiento para la preparacion de una composicion co- loidal lipidica de dihexanoil-lecitina |
Country Status (22)
Country | Link |
---|---|
US (1) | US4271196A (es) |
EP (1) | EP0011745B1 (es) |
JP (1) | JPS5572111A (es) |
KR (1) | KR850000584B1 (es) |
AR (1) | AR225294A1 (es) |
AT (1) | ATE501T1 (es) |
AU (1) | AU529061B2 (es) |
CA (1) | CA1136988A (es) |
DE (1) | DE2961718D1 (es) |
DK (1) | DK494079A (es) |
ES (1) | ES8101855A1 (es) |
FI (1) | FI793461A (es) |
GR (1) | GR73668B (es) |
HU (1) | HU180792B (es) |
IE (1) | IE48659B1 (es) |
IL (1) | IL58723A (es) |
MC (1) | MC1297A1 (es) |
NO (1) | NO793759L (es) |
NZ (1) | NZ192118A (es) |
PH (1) | PH15561A (es) |
PT (1) | PT70478A (es) |
ZA (1) | ZA796116B (es) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2952115C2 (de) * | 1979-12-22 | 1982-05-06 | A. Nattermann & Cie GmbH, 5000 Köln | Rosmarinsäure-Phospholipid-Komplex |
US4374082A (en) * | 1981-08-18 | 1983-02-15 | Richard Hochschild | Method for making a pharmaceutical and/or nutritional dosage form |
US4457918A (en) * | 1982-05-12 | 1984-07-03 | The General Hospital Corporation | Glycosides of vitamins A, E and K |
CA1237670A (en) * | 1983-05-26 | 1988-06-07 | Andrew S. Janoff | Drug preparations of reduced toxicity |
US5059591B1 (en) * | 1983-05-26 | 2000-04-25 | Liposome Co Inc | Drug preparations of reduced toxicity |
US4622219A (en) * | 1983-06-17 | 1986-11-11 | Haynes Duncan H | Method of inducing local anesthesia using microdroplets of a general anesthetic |
JPS60208910A (ja) * | 1984-03-31 | 1985-10-21 | Green Cross Corp:The | 水難溶性薬物・リン脂質複合体の製造方法 |
US5231112A (en) | 1984-04-12 | 1993-07-27 | The Liposome Company, Inc. | Compositions containing tris salt of cholesterol hemisuccinate and antifungal |
US4721612A (en) * | 1984-04-12 | 1988-01-26 | The Liposome Company, Inc. | Steroidal liposomes |
US4891208A (en) * | 1985-04-10 | 1990-01-02 | The Liposome Company, Inc. | Steroidal liposomes |
PT78628B (en) * | 1984-05-02 | 1986-06-18 | Liposome Co Inc | Pharmaceutical composition with reduced toxicity |
US5023271A (en) * | 1985-08-13 | 1991-06-11 | California Biotechnology Inc. | Pharmaceutical microemulsions |
US4861580A (en) * | 1985-10-15 | 1989-08-29 | The Liposome Company, Inc. | Composition using salt form of organic acid derivative of alpha-tocopheral |
US5041278A (en) * | 1985-10-15 | 1991-08-20 | The Liposome Company, Inc. | Alpha tocopherol-based vesicles |
CA1319886C (en) * | 1987-02-03 | 1993-07-06 | Alberto Ferro | Mixed micelle solutions |
IT1269569B (it) * | 1994-04-22 | 1997-04-08 | Ugo Citernesi | Procedimento per la preparazione di complessi fra fosfolipidi e principi attivi utili per la produzione di liposomi e principi attivi e liposomi ottenuti con il procedimento |
EP0682943B1 (de) * | 1994-05-20 | 2003-08-20 | GESELLSCHAFT FÜR MEDIZINISCHE FORSCHUNG UND WEITERBILDUNG e.V. GMF | Lormetazepamhaltige Öl-in-Wasser-Emulsion |
JP2740153B2 (ja) * | 1995-03-07 | 1998-04-15 | エフ・ホフマン−ラ ロシユ アーゲー | 混合ミセル |
DE69637441T2 (de) * | 1995-10-17 | 2009-03-05 | Jagotec Ag | Verabreichung unlöslicher arzneistoffe |
US7255877B2 (en) * | 1996-08-22 | 2007-08-14 | Jagotec Ag | Fenofibrate microparticles |
US6465016B2 (en) | 1996-08-22 | 2002-10-15 | Research Triangle Pharmaceuticals | Cyclosporiine particles |
WO1999040906A2 (en) * | 1998-02-11 | 1999-08-19 | Research Triangle Pharmaceuticals | Method and composition for treatment of inflammatory conditions |
US6979456B1 (en) | 1998-04-01 | 2005-12-27 | Jagotec Ag | Anticancer compositions |
AU764001B2 (en) | 1998-05-29 | 2003-08-07 | Skyepharma Canada Inc. | Thermoprotected microparticle compositions and process for terminal steam sterilization thereof |
EP1105096B1 (en) | 1998-08-19 | 2003-10-29 | Skyepharma Canada Inc. | Injectable aqueous dispersions of propofol |
ID29270A (id) | 1998-11-20 | 2001-08-16 | Rtp Pharma Inc | Partikel-partikel mikro yang distabilkan oleh fosfolipid yang dapat menyebar |
US6447806B1 (en) | 1999-02-25 | 2002-09-10 | Novartis Ag | Pharmaceutical compositions comprised of stabilized peptide particles |
ATE296091T1 (de) * | 1999-09-21 | 2005-06-15 | Skyepharma Canada Inc | Oberflächenmodifizierte teilchenförmige zusammensetzungen biologisch aktiver stoffe |
NZ522239A (en) | 2000-04-20 | 2004-03-26 | Skyepharma Canada Inc | Improved water-insoluble drug particle process |
WO2002017883A2 (en) | 2000-08-31 | 2002-03-07 | Rtp Pharma Inc. | Milled particles |
US8586094B2 (en) * | 2000-09-20 | 2013-11-19 | Jagotec Ag | Coated tablets |
ATE522211T1 (de) * | 2000-09-20 | 2011-09-15 | Jagotec Ag | Stabilisierte fibrat-mikropartikel |
JP2004523552A (ja) * | 2001-02-22 | 2004-08-05 | スカイファーマ・カナダ・インコーポレーテッド | 低減した摂食−絶食効果を伴うフィブラート−スタチンの組合わせ |
FR2833842B1 (fr) * | 2001-12-21 | 2004-02-13 | Aventis Pharma Sa | Compositions pharmaceutiques a base de derives d'azetidine |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
LU28584A1 (es) * | ||||
LU29060A1 (es) * | ||||
FR2102537A5 (es) * | 1970-08-07 | 1972-04-07 | Ugine Kuhlmann | |
FR2270887A1 (en) * | 1974-05-16 | 1975-12-12 | Chabrier De Lassauniere Pierre | Prepn of lecithins and glycol-lecithins - by reaction of trimethylamine with 2-substd-2-oxo-1,3,2-dioxaphospholans |
SE442014B (sv) * | 1976-10-12 | 1985-11-25 | Barry D Sears | Syntetisk fosfatidyl-kvarter ammoniumforening till anvendning for solubilisering eller emulgering av vattenolosliga foreningar |
-
1979
- 1979-01-24 GR GR60545A patent/GR73668B/el unknown
- 1979-10-03 CA CA000336919A patent/CA1136988A/en not_active Expired
- 1979-10-24 AR AR278611A patent/AR225294A1/es active
- 1979-11-05 FI FI793461A patent/FI793461A/fi not_active Application Discontinuation
- 1979-11-08 DE DE7979104378T patent/DE2961718D1/de not_active Expired
- 1979-11-08 AT AT79104378T patent/ATE501T1/de not_active IP Right Cessation
- 1979-11-08 EP EP79104378A patent/EP0011745B1/de not_active Expired
- 1979-11-12 PH PH23274A patent/PH15561A/en unknown
- 1979-11-14 AU AU52824/79A patent/AU529061B2/en not_active Ceased
- 1979-11-14 NZ NZ192118A patent/NZ192118A/xx unknown
- 1979-11-14 IL IL58723A patent/IL58723A/xx unknown
- 1979-11-14 ZA ZA00796116A patent/ZA796116B/xx unknown
- 1979-11-15 MC MC791415A patent/MC1297A1/xx unknown
- 1979-11-16 US US06/094,813 patent/US4271196A/en not_active Expired - Lifetime
- 1979-11-16 HU HU79HO2196A patent/HU180792B/hu unknown
- 1979-11-19 JP JP14903879A patent/JPS5572111A/ja active Granted
- 1979-11-20 DK DK494079A patent/DK494079A/da not_active Application Discontinuation
- 1979-11-20 IE IE2216/79A patent/IE48659B1/en unknown
- 1979-11-20 KR KR7904064A patent/KR850000584B1/ko active
- 1979-11-20 PT PT70478A patent/PT70478A/pt unknown
- 1979-11-20 ES ES486157A patent/ES8101855A1/es not_active Expired
- 1979-11-20 NO NO793759A patent/NO793759L/no unknown
Also Published As
Publication number | Publication date |
---|---|
EP0011745A1 (de) | 1980-06-11 |
DE2961718D1 (en) | 1982-02-18 |
ATE501T1 (de) | 1982-01-15 |
AR225294A1 (es) | 1982-03-15 |
FI793461A (fi) | 1980-05-22 |
KR850000584B1 (ko) | 1985-04-30 |
IE48659B1 (en) | 1985-04-03 |
CA1136988A (en) | 1982-12-07 |
IE792216L (en) | 1980-05-21 |
ZA796116B (en) | 1980-11-26 |
NO793759L (no) | 1980-05-22 |
PT70478A (en) | 1979-12-01 |
JPH0122243B2 (es) | 1989-04-25 |
ES486157A0 (es) | 1981-01-16 |
EP0011745B1 (de) | 1981-12-30 |
IL58723A0 (en) | 1980-02-29 |
IL58723A (en) | 1982-11-30 |
JPS5572111A (en) | 1980-05-30 |
AU529061B2 (en) | 1983-05-26 |
GR73668B (es) | 1984-03-28 |
AU5282479A (en) | 1980-05-29 |
MC1297A1 (fr) | 1980-10-03 |
PH15561A (en) | 1983-02-11 |
HU180792B (en) | 1983-04-29 |
US4271196A (en) | 1981-06-02 |
NZ192118A (en) | 1981-12-15 |
DK494079A (da) | 1980-05-22 |
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