JPS5571497A - Preparation of amoxicillin - Google Patents
Preparation of amoxicillinInfo
- Publication number
- JPS5571497A JPS5571497A JP14308678A JP14308678A JPS5571497A JP S5571497 A JPS5571497 A JP S5571497A JP 14308678 A JP14308678 A JP 14308678A JP 14308678 A JP14308678 A JP 14308678A JP S5571497 A JPS5571497 A JP S5571497A
- Authority
- JP
- Japan
- Prior art keywords
- amoxicillin
- hydantoin
- hydroxyphenyl
- microorganisms
- culture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PURPOSE: To prepare amoxicillin directly, by using 6-aminopenicillanic acid and 5- (p-hydroxyphenyl)hydantoin in the presence of a culture of specific microorganisms or its treated one.
CONSTITUTION: Microorganisms, e.g. Pseudomonas hydantoinophilum (FERM-P Mo.4347), which belong to the genus Pseudomonas, Arthrobacter, Alcaligenes, Achromobacter, Moraxella, or Paracoccus, and have the ability to produce amoxicillin from 6-aminopenicillanic acid and 5-(p-hydroxyphenyl)hydantoin, are cultured to give a culture or its treated one (C). 6-Amino-penicillanic acid is reacted with 5-(p-hydroxyphenyl)hydantoin in the presence of (C), or both are subjected to the enzyme reaction simultaneously with the culturing of the microorganisms.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14308678A JPS5571497A (en) | 1978-11-20 | 1978-11-20 | Preparation of amoxicillin |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14308678A JPS5571497A (en) | 1978-11-20 | 1978-11-20 | Preparation of amoxicillin |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5571497A true JPS5571497A (en) | 1980-05-29 |
Family
ID=15330578
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP14308678A Pending JPS5571497A (en) | 1978-11-20 | 1978-11-20 | Preparation of amoxicillin |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5571497A (en) |
-
1978
- 1978-11-20 JP JP14308678A patent/JPS5571497A/en active Pending
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