JPS5571497A - Preparation of amoxicillin - Google Patents

Preparation of amoxicillin

Info

Publication number
JPS5571497A
JPS5571497A JP14308678A JP14308678A JPS5571497A JP S5571497 A JPS5571497 A JP S5571497A JP 14308678 A JP14308678 A JP 14308678A JP 14308678 A JP14308678 A JP 14308678A JP S5571497 A JPS5571497 A JP S5571497A
Authority
JP
Japan
Prior art keywords
amoxicillin
hydantoin
hydroxyphenyl
microorganisms
culture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP14308678A
Other languages
Japanese (ja)
Inventor
Kenzo Yokozeki
Shigeru Nakamori
Fumihiro Yoshinaga
Shigeru Yamanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Priority to JP14308678A priority Critical patent/JPS5571497A/en
Publication of JPS5571497A publication Critical patent/JPS5571497A/en
Pending legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PURPOSE: To prepare amoxicillin directly, by using 6-aminopenicillanic acid and 5- (p-hydroxyphenyl)hydantoin in the presence of a culture of specific microorganisms or its treated one.
CONSTITUTION: Microorganisms, e.g. Pseudomonas hydantoinophilum (FERM-P Mo.4347), which belong to the genus Pseudomonas, Arthrobacter, Alcaligenes, Achromobacter, Moraxella, or Paracoccus, and have the ability to produce amoxicillin from 6-aminopenicillanic acid and 5-(p-hydroxyphenyl)hydantoin, are cultured to give a culture or its treated one (C). 6-Amino-penicillanic acid is reacted with 5-(p-hydroxyphenyl)hydantoin in the presence of (C), or both are subjected to the enzyme reaction simultaneously with the culturing of the microorganisms.
COPYRIGHT: (C)1980,JPO&Japio
JP14308678A 1978-11-20 1978-11-20 Preparation of amoxicillin Pending JPS5571497A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP14308678A JPS5571497A (en) 1978-11-20 1978-11-20 Preparation of amoxicillin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14308678A JPS5571497A (en) 1978-11-20 1978-11-20 Preparation of amoxicillin

Publications (1)

Publication Number Publication Date
JPS5571497A true JPS5571497A (en) 1980-05-29

Family

ID=15330578

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14308678A Pending JPS5571497A (en) 1978-11-20 1978-11-20 Preparation of amoxicillin

Country Status (1)

Country Link
JP (1) JPS5571497A (en)

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