JPS5569539A - Bicyclo 3,3,0 octane derivative and its preparation - Google Patents
Bicyclo 3,3,0 octane derivative and its preparationInfo
- Publication number
- JPS5569539A JPS5569539A JP14281978A JP14281978A JPS5569539A JP S5569539 A JPS5569539 A JP S5569539A JP 14281978 A JP14281978 A JP 14281978A JP 14281978 A JP14281978 A JP 14281978A JP S5569539 A JPS5569539 A JP S5569539A
- Authority
- JP
- Japan
- Prior art keywords
- bicyclo
- octane
- formula
- preparation
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:A bicyclo[3,3,0]octane derivative of formula I (A is ketone, ethylenedioxy, H, OH, or protected OH; R1 is H or 1W6C alkyl; n is 1W6).
EXAMPLE: 7-(4-Carboxybutylidene)-3,3-ethylenedioxybicyclo(3,3,0)octane.
USE: An important intermediate of a prostacycline analog which is a useful medicine.
PROCESS: The compound I is prepared by reacting 1 mole of an organo-phosphorus compound of formula II (R2-4 are alkyl or aryl; n is 1W6) with 1W10mol, pref. 3W6mol of bicyclo(3,3,0)octane-3,7-dione monoethylene ketal of formula III, and if necessary, hydrolyzing, reducing, and/or esterifying the reaction product.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14281978A JPS5569539A (en) | 1978-11-21 | 1978-11-21 | Bicyclo 3,3,0 octane derivative and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14281978A JPS5569539A (en) | 1978-11-21 | 1978-11-21 | Bicyclo 3,3,0 octane derivative and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5569539A true JPS5569539A (en) | 1980-05-26 |
Family
ID=15324354
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP14281978A Pending JPS5569539A (en) | 1978-11-21 | 1978-11-21 | Bicyclo 3,3,0 octane derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5569539A (en) |
-
1978
- 1978-11-21 JP JP14281978A patent/JPS5569539A/en active Pending
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