JPS5569539A - Bicyclo 3,3,0 octane derivative and its preparation - Google Patents

Bicyclo 3,3,0 octane derivative and its preparation

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Publication number
JPS5569539A
JPS5569539A JP14281978A JP14281978A JPS5569539A JP S5569539 A JPS5569539 A JP S5569539A JP 14281978 A JP14281978 A JP 14281978A JP 14281978 A JP14281978 A JP 14281978A JP S5569539 A JPS5569539 A JP S5569539A
Authority
JP
Japan
Prior art keywords
bicyclo
octane
formula
preparation
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP14281978A
Other languages
Japanese (ja)
Inventor
Seiji Kurozumi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Priority to JP14281978A priority Critical patent/JPS5569539A/en
Publication of JPS5569539A publication Critical patent/JPS5569539A/en
Pending legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:A bicyclo[3,3,0]octane derivative of formula I (A is ketone, ethylenedioxy, H, OH, or protected OH; R1 is H or 1W6C alkyl; n is 1W6).
EXAMPLE: 7-(4-Carboxybutylidene)-3,3-ethylenedioxybicyclo(3,3,0)octane.
USE: An important intermediate of a prostacycline analog which is a useful medicine.
PROCESS: The compound I is prepared by reacting 1 mole of an organo-phosphorus compound of formula II (R2-4 are alkyl or aryl; n is 1W6) with 1W10mol, pref. 3W6mol of bicyclo(3,3,0)octane-3,7-dione monoethylene ketal of formula III, and if necessary, hydrolyzing, reducing, and/or esterifying the reaction product.
COPYRIGHT: (C)1980,JPO&Japio
JP14281978A 1978-11-21 1978-11-21 Bicyclo 3,3,0 octane derivative and its preparation Pending JPS5569539A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP14281978A JPS5569539A (en) 1978-11-21 1978-11-21 Bicyclo 3,3,0 octane derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14281978A JPS5569539A (en) 1978-11-21 1978-11-21 Bicyclo 3,3,0 octane derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS5569539A true JPS5569539A (en) 1980-05-26

Family

ID=15324354

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14281978A Pending JPS5569539A (en) 1978-11-21 1978-11-21 Bicyclo 3,3,0 octane derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS5569539A (en)

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