JPS55392A - Muramyllpeptide type novel compounds and drug containing them - Google Patents

Muramyllpeptide type novel compounds and drug containing them

Info

Publication number
JPS55392A
JPS55392A JP6953179A JP6953179A JPS55392A JP S55392 A JPS55392 A JP S55392A JP 6953179 A JP6953179 A JP 6953179A JP 6953179 A JP6953179 A JP 6953179A JP S55392 A JPS55392 A JP S55392A
Authority
JP
Japan
Prior art keywords
muramyllpeptide
novel compounds
drug containing
type novel
type
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6953179A
Other languages
English (en)
Other versions
JPH0233720B2 (ja
Inventor
Rufuranshie Pieeru
Paranto Moniiku
Odeibeeru Furansowaazu
Shiedeidou Rui
Shiyoai Jiyan
Rudoure Edogiyaaru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bpifrance Financement SA
Original Assignee
Agence National de Valorisation de la Recherche ANVAR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agence National de Valorisation de la Recherche ANVAR filed Critical Agence National de Valorisation de la Recherche ANVAR
Publication of JPS55392A publication Critical patent/JPS55392A/ja
Publication of JPH0233720B2 publication Critical patent/JPH0233720B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/5555—Muramyl dipeptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP6953179A 1978-06-05 1979-06-05 Muramyllpeptide type novel compounds and drug containing them Granted JPS55392A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7816793A FR2428051A1 (fr) 1978-06-05 1978-06-05 Nouveaux composes du type muramyl-peptide et medicaments les contenant

Publications (2)

Publication Number Publication Date
JPS55392A true JPS55392A (en) 1980-01-05
JPH0233720B2 JPH0233720B2 (ja) 1990-07-30

Family

ID=9209095

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6953179A Granted JPS55392A (en) 1978-06-05 1979-06-05 Muramyllpeptide type novel compounds and drug containing them

Country Status (21)

Country Link
US (1) US4693998A (ja)
EP (1) EP0006068B1 (ja)
JP (1) JPS55392A (ja)
AR (1) AR228240A1 (ja)
AT (1) ATE4719T1 (ja)
AU (1) AU536516B2 (ja)
CA (1) CA1249700A (ja)
CS (1) CS221505B2 (ja)
DD (1) DD145274A5 (ja)
DE (1) DE2966178D1 (ja)
DK (1) DK150147C (ja)
EG (1) EG14154A (ja)
ES (1) ES481785A1 (ja)
FR (1) FR2428051A1 (ja)
HU (1) HU184041B (ja)
IL (1) IL57476A (ja)
MA (1) MA18474A1 (ja)
OA (1) OA06274A (ja)
PL (1) PL123483B1 (ja)
PT (1) PT69725A (ja)
SU (2) SU1326197A3 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56164196A (en) * 1980-04-17 1981-12-17 Merck & Co Inc Immunologically active dipeptidyl-4-0-, 6-0-acyl-2-amino-2-deoxy-d-glucose derivative and manufacture

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5784223A (en) * 1980-11-13 1982-05-26 Nissan Motor Co Ltd Vibration absorber of vehicle
FR2529463B1 (fr) * 1982-07-05 1986-01-10 Centre Nat Rech Scient Procede et dispositif pour l'encapsulation dans les erythrocytes d'au moins une substance a activite biologique, notamment des effecteurs allosteriques de l'hemoglobine et erythrocytes ainsi obtenus
ATE23536T1 (de) * 1982-07-23 1986-11-15 Ciba Geigy Ag Neue muramylpeptide und verfahren zu ihrer herstellung.
US5134230A (en) * 1988-03-02 1992-07-28 Daiichi Pharmaceutical Co., Ltd. 2-Deoxy-2-aminoglucopyranoside derivatives
JPH0832638B2 (ja) 1989-05-25 1996-03-29 カイロン コーポレイション サブミクロン油滴乳剤を含んで成るアジュバント製剤
WO2000068251A1 (en) 1999-05-07 2000-11-16 The University Of Virginia Patent Foundation Biological production of stable glutamine, poly-glutamine derivatives in transgenic organisms and their use for therapeutic purposes
CN109406709B (zh) * 2018-12-27 2020-11-10 福建省中医药研究院(福建省青草药开发服务中心） 一种太子参药材中氨基酸类成分的薄层鉴别方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5273820A (en) * 1975-12-10 1977-06-21 Ciba Geigy Ag Glucosamine derivative and its method of manufacturing
JPS52139018A (en) * 1976-03-10 1977-11-19 Anvar Immuno adjuvant and antiinfection adjuvant composed of mainly nnacetyll muramiccllalanyllddglutamic ester or nnacetyllmuramiccllalanylldd isoglutamic ester

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2292486A1 (fr) * 1974-07-01 1976-06-25 Anvar Adjuvants immunologiques solubles dans l'eau, notamment pour vaccins, obtenus a partir de microbacteries et autres micro-organismes
FR2369292A1 (fr) * 1976-11-02 1978-05-26 Anvar Agents adjuvants immunit
US4153684A (en) * 1976-03-10 1979-05-08 Agence Nationale De Valorisation De La Recherche (Anvar) Immunizing and anti-infectious adjuvant agents constituted by N-acetyl-muramyl-L-alanyl-D-glutamic acid derivatives
FR2355505A1 (fr) * 1976-06-24 1978-01-20 Anvar Nouvel agent adjuvant immunitaire
FR2358159A1 (fr) * 1976-07-16 1978-02-10 Anvar Le diamide de l'acide 2-(2-acetamido-2-deoxy-3 - o-d-glucopyranosyl) - d-propionyl-l-alanyl-d-glutamique et medicaments le contenant
FR2368282A1 (fr) * 1976-10-22 1978-05-19 Anvar Adjuvant immunologique constitue par le p-amino-phenyl de n-acetyl-muramyl-l-alanyl-d-isoglutamine
EP0003833B2 (de) * 1978-02-24 1990-12-19 Ciba-Geigy Ag Antigenderivate, Verfahren zu deren Herstellung, diese enthaltende pharmazeutische Präparate

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5273820A (en) * 1975-12-10 1977-06-21 Ciba Geigy Ag Glucosamine derivative and its method of manufacturing
JPS52139018A (en) * 1976-03-10 1977-11-19 Anvar Immuno adjuvant and antiinfection adjuvant composed of mainly nnacetyll muramiccllalanyllddglutamic ester or nnacetyllmuramiccllalanylldd isoglutamic ester

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56164196A (en) * 1980-04-17 1981-12-17 Merck & Co Inc Immunologically active dipeptidyl-4-0-, 6-0-acyl-2-amino-2-deoxy-d-glucose derivative and manufacture

Also Published As

Publication number Publication date
EP0006068A3 (en) 1980-01-09
AU536516B2 (en) 1984-05-10
OA06274A (fr) 1981-06-30
EG14154A (en) 1983-09-30
IL57476A (en) 1984-06-29
MA18474A1 (fr) 1979-12-31
ES481785A1 (es) 1980-02-16
PT69725A (fr) 1979-07-01
PL123483B1 (en) 1982-10-30
DK150147C (da) 1988-01-18
AR228240A1 (es) 1983-02-15
US4693998A (en) 1987-09-15
CS221505B2 (en) 1983-04-29
EP0006068B1 (fr) 1983-09-21
SU1346046A3 (ru) 1987-10-15
PL216102A1 (ja) 1980-03-24
SU1326197A3 (ru) 1987-07-23
FR2428051B1 (ja) 1981-12-04
IL57476A0 (en) 1979-10-31
HU184041B (en) 1984-06-28
CA1249700A (en) 1989-01-31
ATE4719T1 (de) 1983-10-15
JPH0233720B2 (ja) 1990-07-30
DD145274A5 (de) 1980-12-03
DK150147B (da) 1986-12-15
AU4775679A (en) 1979-12-13
DE2966178D1 (en) 1983-10-27
FR2428051A1 (fr) 1980-01-04
DK229479A (da) 1979-12-06
EP0006068A2 (fr) 1979-12-12

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