JPS55329A - Novel xk-62-4 derivative - Google Patents

Novel xk-62-4 derivative

Info

Publication number
JPS55329A
JPS55329A JP7329178A JP7329178A JPS55329A JP S55329 A JPS55329 A JP S55329A JP 7329178 A JP7329178 A JP 7329178A JP 7329178 A JP7329178 A JP 7329178A JP S55329 A JPS55329 A JP S55329A
Authority
JP
Japan
Prior art keywords
formula
group
compound
derivative
concentrated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7329178A
Other languages
Japanese (ja)
Inventor
Shinji Tomioka
Yuko Yamamoto
Taijo Mori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP7329178A priority Critical patent/JPS55329A/en
Publication of JPS55329A publication Critical patent/JPS55329A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:An XK-62-4 derivative of formula I: (n is 1, 2, or 3) or its acid addition salt.
EXAMPLE: 1-N-(α-Hydroxy-β-aminopropionyl)XK-62-4.
USE: Antibiotics having antibacterial activities against Gram-positive and Gram- negative bacteria, particularly Escherichia coli resistant to aminoglycoside antibiotics.
PROCESS: The amino group at the 2'-position of the XK-62-4 of formula II is protected by an amino-protecting agent in a solvent, e.g. tetrahydrofuran, at -50 to 50°C to give a compound of formula III: (Y1 is H; Y2 is group of formula IV, etc.), which is concentrated and acylated with an acylating agent to form a compound of formula V: (Y3 is H; Y4 is group of formula IV, etc.), which is concentrated. The protecting group is eliminated by the well-known method to afford the compound of formula I.
COPYRIGHT: (C)1980,JPO&Japio
JP7329178A 1978-06-19 1978-06-19 Novel xk-62-4 derivative Pending JPS55329A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP7329178A JPS55329A (en) 1978-06-19 1978-06-19 Novel xk-62-4 derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7329178A JPS55329A (en) 1978-06-19 1978-06-19 Novel xk-62-4 derivative

Publications (1)

Publication Number Publication Date
JPS55329A true JPS55329A (en) 1980-01-05

Family

ID=13513896

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7329178A Pending JPS55329A (en) 1978-06-19 1978-06-19 Novel xk-62-4 derivative

Country Status (1)

Country Link
JP (1) JPS55329A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4634796A (en) * 1985-03-25 1987-01-06 Lummus Crest, Inc. Production of high purity phenol
WO2010132765A3 (en) * 2009-05-15 2011-06-23 Achaogen, Inc. Antibacterial aminoglycoside analogs
US9266919B2 (en) 2007-11-21 2016-02-23 Achaogen, Inc. Antibacterial aminoglycoside analogs
USRE47741E1 (en) 2009-05-15 2019-11-26 Achaogen, Inc. Antibacterial aminoglycoside analogs

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4634796A (en) * 1985-03-25 1987-01-06 Lummus Crest, Inc. Production of high purity phenol
US9266919B2 (en) 2007-11-21 2016-02-23 Achaogen, Inc. Antibacterial aminoglycoside analogs
US9688711B2 (en) 2007-11-21 2017-06-27 Achaogen, Inc. Antibacterial aminoglycoside analogs
US11117915B2 (en) 2007-11-21 2021-09-14 Cipla USA, Inc. Antibacterial aminoglycoside analogs
WO2010132765A3 (en) * 2009-05-15 2011-06-23 Achaogen, Inc. Antibacterial aminoglycoside analogs
USRE47741E1 (en) 2009-05-15 2019-11-26 Achaogen, Inc. Antibacterial aminoglycoside analogs

Similar Documents

Publication Publication Date Title
JPS54132592A (en) 3,7-di-substituted-3-cephem-4-carboxylic acid derivative, its salt, and their preparation
JPS5777689A (en) Novel cephen compound, or its salt, its preparation, and preventive it as active ingredient
JPS5798288A (en) Novel cephem compound or its salt, their preparation, and preventive and remedy for bacteriosis containing said compound as active component
JPS5748957A (en) Novel antibiotic bmg 162-af2, its preparation and carcinostatic agent comprising it as active ingredient
JPS55329A (en) Novel xk-62-4 derivative
JPS5540621A (en) Novel aminoglycoside derivative
IE780841L (en) Kanamycin derivatives
JPS5557600A (en) Polyenemacrolide antibiotic
JPS57142983A (en) 1-vinyl-1,8-naphthyridine derivative and its salt
JPS57136555A (en) Novel peptide and its preparation
SE7511229L (en) ANTIQUE BACTERIAL AGENT
ES435375A1 (en) Derivative of antibiotic xk-62-2 and method of production thereof
CA1175817A (en) Di-n su6' xx, o.sup.3-demethylistamycin a and preparation thereof
JPS57116091A (en) Novel beta-lactam compound and its preparation
JPS5753496A (en) 1-n-acyl derivative of 5,3',4'-trideoxykanamycin b or 5,3',4',6'- tetradeoxykanamycin b, and their preparation
JPS57158784A (en) 3-substituted-6-substituted-7-oxo-1-azabicyclo(3,2,0)hept- 2-ene-carboxylic acid derivative
JPS55162796A (en) Fortimicin al and its preparation
JPS55162790A (en) Novel fortimicin compound and its preparation
JPS5620598A (en) Novel antibiotic and its preparation
JPS5750993A (en) Novel antibacterial compound
JPS57175192A (en) 7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivative
JPS56150080A (en) Formimidoylistamycin b and its preparation
JPS5625188A (en) 7alpha-methoxycephalosporin
JPS57118544A (en) Novel peptide and its preparation
JPS5732298A (en) Formimidoyl istamycin a and its preparation