JPS57118544A - Novel peptide and its preparation - Google Patents
Novel peptide and its preparationInfo
- Publication number
- JPS57118544A JPS57118544A JP56192506A JP19250681A JPS57118544A JP S57118544 A JPS57118544 A JP S57118544A JP 56192506 A JP56192506 A JP 56192506A JP 19250681 A JP19250681 A JP 19250681A JP S57118544 A JPS57118544 A JP S57118544A
- Authority
- JP
- Japan
- Prior art keywords
- lower alkyl
- formula
- amino
- compound
- hydroxymethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
NEW MATERIAL:The peptide (salt) of formulaI[R1 is H or acyl; R2 is H or lower alkyl; R3 and R6 are (protected) carboxy, carbamoyl, etc.; R4 is H or (hydroxy)lower alkyl; R5 is H, carboxy(lower alkyl), etc.; R7 is H or amino- protecting group; n is 0 or 1; when R3 and R6 are not hydroxymethyl, one of R4 and R6 is hydroxy lower alkyl].
EXAMPLE: D-Lac-L-Ala-γ-D-(α-amino-α-hydroxymethyl)butyryl-(L)-mesoDAP-(L)- GlyOH of formula II.
USE: Remedy for infectious diseases caused by pathogenic microorganisms such as Gram-negative becteria, Gram-positive bacteria, fungi, etc.
PROCESS: The compound of formula V (Ra 1 is acyl; Ra 3 is protected carboxyl, etc.; Ra 7 is amino-protecting group) is prepared by reacting e.g. the compound of formula III with the compound of formula IV. The starting raw material of formula III wherein Ra 3 is R3 is novel substance.
COPYRIGHT: (C)1982,JPO&Japio
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8038509 | 1980-12-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57118544A true JPS57118544A (en) | 1982-07-23 |
JPH0325414B2 JPH0325414B2 (en) | 1991-04-05 |
Family
ID=10517687
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56192506A Granted JPS57118544A (en) | 1980-12-01 | 1981-11-30 | Novel peptide and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57118544A (en) |
-
1981
- 1981-11-30 JP JP56192506A patent/JPS57118544A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPH0325414B2 (en) | 1991-04-05 |
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