JPS5531024A - Anti-tumor agent - Google Patents

Anti-tumor agent

Info

Publication number
JPS5531024A
JPS5531024A JP10354978A JP10354978A JPS5531024A JP S5531024 A JPS5531024 A JP S5531024A JP 10354978 A JP10354978 A JP 10354978A JP 10354978 A JP10354978 A JP 10354978A JP S5531024 A JPS5531024 A JP S5531024A
Authority
JP
Japan
Prior art keywords
compound
prepared
condensing agent
tumor agent
day
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10354978A
Other languages
Japanese (ja)
Inventor
Masaaki Nomura
Yoshio Kozai
Isao Minami
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP10354978A priority Critical patent/JPS5531024A/en
Priority to DE19792919447 priority patent/DE2919447A1/en
Priority to FR7912486A priority patent/FR2425857A1/en
Priority to GB7917270A priority patent/GB2020975B/en
Publication of JPS5531024A publication Critical patent/JPS5531024A/en
Pending legal-status Critical Current

Links

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: To provide an anti-tumor agent containing a methinecyanine, and effective to leukemia of warm-blooded animals, and other malignant tumors.
CONSTITUTION: An anti-tumor agent containing a compound of formula A-(CH= CH)n-CH=A' (n is 0W3; A is I (R is alkyl; R' is H, alkyl, alkoxy, etc.; X- is anion), etc.; A' is II, etc.], e.g. a compound of formula III. Dose: 0.002W5mg/kg/ day, pref. 0.1W2.5mg/kg/day for parenteral administration, such as injection. Orally administrable in the form of powder, tablet, etc. The effective compound III, etc. can be prepared by the reaction of a compound IV with a compound V directly or in the presence of a proper condensing agent. For example, trimethinecyanine is prepared by using formaldehyde etc. as the condensing agent, and pentamethinecyanine is prepared by using 1-anilino-3-aniloprop-1-ene, etc. as the condensing agent.
COPYRIGHT: (C)1980,JPO&Japio
JP10354978A 1978-05-17 1978-08-24 Anti-tumor agent Pending JPS5531024A (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP10354978A JPS5531024A (en) 1978-08-24 1978-08-24 Anti-tumor agent
DE19792919447 DE2919447A1 (en) 1978-05-17 1979-05-15 ANTI-TUMORIC AGENT
FR7912486A FR2425857A1 (en) 1978-05-17 1979-05-16 ANTIMITOTIC AGENTS CONTAINING A CYANINE
GB7917270A GB2020975B (en) 1978-05-17 1979-05-17 Compositions containg cyanine compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10354978A JPS5531024A (en) 1978-08-24 1978-08-24 Anti-tumor agent

Publications (1)

Publication Number Publication Date
JPS5531024A true JPS5531024A (en) 1980-03-05

Family

ID=14356896

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10354978A Pending JPS5531024A (en) 1978-05-17 1978-08-24 Anti-tumor agent

Country Status (1)

Country Link
JP (1) JPS5531024A (en)

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