JPS55153724A - Preparation of immunoglobulin derivative - Google Patents
Preparation of immunoglobulin derivativeInfo
- Publication number
- JPS55153724A JPS55153724A JP5971079A JP5971079A JPS55153724A JP S55153724 A JPS55153724 A JP S55153724A JP 5971079 A JP5971079 A JP 5971079A JP 5971079 A JP5971079 A JP 5971079A JP S55153724 A JPS55153724 A JP S55153724A
- Authority
- JP
- Japan
- Prior art keywords
- persulfate
- immunoglobulin
- cleaved
- disulfide bonds
- ion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108060003951 Immunoglobulin Proteins 0.000 title abstract 4
- 102000018358 immunoglobulin Human genes 0.000 title abstract 4
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 abstract 2
- ROOXNKNUYICQNP-UHFFFAOYSA-N ammonium persulfate Chemical compound [NH4+].[NH4+].[O-]S(=O)(=O)OOS([O-])(=O)=O ROOXNKNUYICQNP-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000007800 oxidant agent Substances 0.000 abstract 2
- 230000001590 oxidative effect Effects 0.000 abstract 2
- JRKICGRDRMAZLK-UHFFFAOYSA-L peroxydisulfate Chemical compound [O-]S(=O)(=O)OOS([O-])(=O)=O JRKICGRDRMAZLK-UHFFFAOYSA-L 0.000 abstract 2
- LCPVQAHEFVXVKT-UHFFFAOYSA-N 2-(2,4-difluorophenoxy)pyridin-3-amine Chemical compound NC1=CC=CN=C1OC1=CC=C(F)C=C1F LCPVQAHEFVXVKT-UHFFFAOYSA-N 0.000 abstract 1
- 229910001870 ammonium persulfate Inorganic materials 0.000 abstract 1
- 230000002391 anti-complement effect Effects 0.000 abstract 1
- 108010008730 anticomplement Proteins 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- USHAGKDGDHPEEY-UHFFFAOYSA-L potassium persulfate Chemical compound [K+].[K+].[O-]S(=O)(=O)OOS([O-])(=O)=O USHAGKDGDHPEEY-UHFFFAOYSA-L 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- CHQMHPLRPQMAMX-UHFFFAOYSA-L sodium persulfate Substances [Na+].[Na+].[O-]S(=O)(=O)OOS([O-])(=O)=O CHQMHPLRPQMAMX-UHFFFAOYSA-L 0.000 abstract 1
- HPQYKCJIWQFJMS-UHFFFAOYSA-L tetrathionate(2-) Chemical class [O-]S(=O)(=O)SSS([O-])(=O)=O HPQYKCJIWQFJMS-UHFFFAOYSA-L 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5971079A JPS55153724A (en) | 1979-05-17 | 1979-05-17 | Preparation of immunoglobulin derivative |
| SE8003591A SE435787B (sv) | 1979-05-17 | 1980-05-13 | Forfarande for framstellning av immunoglobulinderivat |
| CH379780A CH644130A5 (en) | 1979-05-17 | 1980-05-14 | Process for the preparation of immunoglobulin derivatives |
| DE19803018901 DE3018901C2 (de) | 1979-05-17 | 1980-05-16 | Verfahren zur Herstellung von Immunoglobulinderivaten |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5971079A JPS55153724A (en) | 1979-05-17 | 1979-05-17 | Preparation of immunoglobulin derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS55153724A true JPS55153724A (en) | 1980-11-29 |
| JPS62886B2 JPS62886B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1987-01-10 |
Family
ID=13121030
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP5971079A Granted JPS55153724A (en) | 1979-05-17 | 1979-05-17 | Preparation of immunoglobulin derivative |
Country Status (4)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58203919A (ja) * | 1982-05-05 | 1983-11-28 | イ−・アイ・デュポン・ドゥ・ヌム−ル・アンド・カンパニ− | 免疫グロブリン半分子および交雑種抗体を製造する方法 |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU590754B2 (en) * | 1985-05-01 | 1989-11-16 | Commonwealth Serum Laboratories Commission | Novel molecular weight standards and methods of use thereof |
| NZ215967A (en) * | 1985-05-01 | 1988-05-30 | Commw Serum Lab Commission | Composition of peptides of known weight for determining weight of unknown peptide |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS511630A (ja) * | 1974-06-24 | 1976-01-08 | Teijin Ltd | Jomyakuchushayomenekiguroburinno seizoho |
-
1979
- 1979-05-17 JP JP5971079A patent/JPS55153724A/ja active Granted
-
1980
- 1980-05-13 SE SE8003591A patent/SE435787B/sv not_active IP Right Cessation
- 1980-05-14 CH CH379780A patent/CH644130A5/de not_active IP Right Cessation
- 1980-05-16 DE DE19803018901 patent/DE3018901C2/de not_active Expired
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS511630A (ja) * | 1974-06-24 | 1976-01-08 | Teijin Ltd | Jomyakuchushayomenekiguroburinno seizoho |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58203919A (ja) * | 1982-05-05 | 1983-11-28 | イ−・アイ・デュポン・ドゥ・ヌム−ル・アンド・カンパニ− | 免疫グロブリン半分子および交雑種抗体を製造する方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| SE435787B (sv) | 1984-10-22 |
| JPS62886B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1987-01-10 |
| SE8003591L (sv) | 1980-11-18 |
| DE3018901A1 (de) | 1980-11-20 |
| DE3018901C2 (de) | 1982-04-22 |
| CH644130A5 (en) | 1984-07-13 |
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