JPS55136298A - Preparation of 3"-acylated macrolide antibiotic - Google Patents
Preparation of 3"-acylated macrolide antibioticInfo
- Publication number
- JPS55136298A JPS55136298A JP4459079A JP4459079A JPS55136298A JP S55136298 A JPS55136298 A JP S55136298A JP 4459079 A JP4459079 A JP 4459079A JP 4459079 A JP4459079 A JP 4459079A JP S55136298 A JPS55136298 A JP S55136298A
- Authority
- JP
- Japan
- Prior art keywords
- group
- acylated
- macrolide antibiotic
- alkanoyl group
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003120 macrolide antibiotic agent Substances 0.000 title abstract 3
- 125000002252 acyl group Chemical group 0.000 abstract 6
- -1 aliphatic carboxylic acid halide Chemical class 0.000 abstract 2
- IJOOHPMOJXWVHK-UHFFFAOYSA-N chlorotrimethylsilane Chemical compound C[Si](C)(C)Cl IJOOHPMOJXWVHK-UHFFFAOYSA-N 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- WETWJCDKMRHUPV-UHFFFAOYSA-N acetyl chloride Chemical compound CC(Cl)=O WETWJCDKMRHUPV-UHFFFAOYSA-N 0.000 abstract 1
- 239000012346 acetyl chloride Substances 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 125000003808 silyl group Chemical group [H][Si]([H])([H])[*] 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- 239000005051 trimethylchlorosilane Substances 0.000 abstract 1
Landscapes
- Saccharide Compounds (AREA)
Priority Applications (15)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4459079A JPS55136298A (en) | 1979-04-12 | 1979-04-12 | Preparation of 3"-acylated macrolide antibiotic |
SE7903794A SE445556B (sv) | 1978-05-10 | 1979-04-30 | Nya 3"-acylerade makrolidantibiotika |
FR7911577A FR2425450A1 (fr) | 1978-05-10 | 1979-05-08 | Nouveaux antibiotiques macrolides acyles a la position 3'' |
GB7915907A GB2023596B (en) | 1978-05-10 | 1979-05-08 | 3-acylated macrolide antibiotics |
HU79TO1107A HU181973B (en) | 1978-05-10 | 1979-05-09 | Process for preparing macrolide antibiotics acylated in position 3" |
DK190779A DK152844C (da) | 1978-05-10 | 1979-05-09 | Analogifremgangsmaade til fremstilling af 3ae-acylerede macrolidantibiotika |
CH434479A CH641474A5 (de) | 1978-05-10 | 1979-05-09 | 3''-acylierte macrolide antibiotika. |
DE19792918954 DE2918954A1 (de) | 1978-05-10 | 1979-05-10 | 3''-acylierte makrolidantibiotika |
IT67996/79A IT1165201B (it) | 1978-05-10 | 1979-05-10 | Antibiotici macrolidici 3 acilati |
US06/037,859 US4242504A (en) | 1978-05-10 | 1979-05-10 | 3"-Acylated macrolide antibiotics |
AT0349279A AT372092B (de) | 1978-05-10 | 1979-05-10 | Verfahren zur herstellung von neuen 3''acylierten makrolid-antibiotika und von deren salzen |
NLAANVRAGE7903704,A NL188529C (nl) | 1978-05-10 | 1979-05-10 | 3"-geacyleerd macrolide antibioticum. |
AT325083A AT377266B (de) | 1979-04-12 | 1983-09-12 | Verfahren zur herstellung von neuen 3"-acylierten makrolid-antibiotika |
DK076386A DK154144C (da) | 1978-05-10 | 1986-02-19 | Analogifremgangsmaade til fremstilling af 3ae-acylerede macrolidantibiotika |
DK076486A DK154565C (da) | 1978-05-10 | 1986-02-19 | Analogifremgangsmaade til fremstilling af 3ae-acylerede macrolid antibiotika |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4459079A JPS55136298A (en) | 1979-04-12 | 1979-04-12 | Preparation of 3"-acylated macrolide antibiotic |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS55136298A true JPS55136298A (en) | 1980-10-23 |
JPS6154037B2 JPS6154037B2 (enrdf_load_stackoverflow) | 1986-11-20 |
Family
ID=12695681
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP4459079A Granted JPS55136298A (en) | 1978-05-10 | 1979-04-12 | Preparation of 3"-acylated macrolide antibiotic |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55136298A (enrdf_load_stackoverflow) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63110319A (ja) * | 1986-10-28 | 1988-05-14 | Dainippon Doboku Kk | 盛土の安定工法 |
-
1979
- 1979-04-12 JP JP4459079A patent/JPS55136298A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6154037B2 (enrdf_load_stackoverflow) | 1986-11-20 |
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