JPS5513253A - Cis-3-aralkyl substituted-8-benzoylthio-6,11-dimethyl-2,6- methano-1,2,3,4,5,6-hexahydro-3-benzazocine or its acid addition salt - Google Patents

Cis-3-aralkyl substituted-8-benzoylthio-6,11-dimethyl-2,6- methano-1,2,3,4,5,6-hexahydro-3-benzazocine or its acid addition salt

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Publication number
JPS5513253A
JPS5513253A JP8666178A JP8666178A JPS5513253A JP S5513253 A JPS5513253 A JP S5513253A JP 8666178 A JP8666178 A JP 8666178A JP 8666178 A JP8666178 A JP 8666178A JP S5513253 A JPS5513253 A JP S5513253A
Authority
JP
Japan
Prior art keywords
benzazocine
methano
hexahydro
cis
dimethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8666178A
Other languages
Japanese (ja)
Inventor
Mikio Hori
Hajime Fujimura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Institute for Production Development
Zaidan Hojin Seisan Kaihatsu Kenkyusho
Original Assignee
Research Institute for Production Development
Zaidan Hojin Seisan Kaihatsu Kenkyusho
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Institute for Production Development, Zaidan Hojin Seisan Kaihatsu Kenkyusho filed Critical Research Institute for Production Development
Priority to JP8666178A priority Critical patent/JPS5513253A/en
Publication of JPS5513253A publication Critical patent/JPS5513253A/en
Pending legal-status Critical Current

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  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:The title compound of formula I [R is phenethyl, 2-(2-thienyl) ethyl, or benzyl group].
USE: Analgesics.
PROCESS: A cis-3-aralkyl substituted-8-(dimethylcarbamoylthio)-6,11-dimethyl-2,6- methano-1,2,3,4,5,6-hexahydro-3-benzazocine of formula II is reacted with lithium aluminum hydride and then a benzoyl halide to give the objective compound. The novel compound of formula II can be prepared according to the reaction formula.
COPYRIGHT: (C)1980,JPO&Japio
JP8666178A 1978-07-15 1978-07-15 Cis-3-aralkyl substituted-8-benzoylthio-6,11-dimethyl-2,6- methano-1,2,3,4,5,6-hexahydro-3-benzazocine or its acid addition salt Pending JPS5513253A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8666178A JPS5513253A (en) 1978-07-15 1978-07-15 Cis-3-aralkyl substituted-8-benzoylthio-6,11-dimethyl-2,6- methano-1,2,3,4,5,6-hexahydro-3-benzazocine or its acid addition salt

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8666178A JPS5513253A (en) 1978-07-15 1978-07-15 Cis-3-aralkyl substituted-8-benzoylthio-6,11-dimethyl-2,6- methano-1,2,3,4,5,6-hexahydro-3-benzazocine or its acid addition salt

Publications (1)

Publication Number Publication Date
JPS5513253A true JPS5513253A (en) 1980-01-30

Family

ID=13893207

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8666178A Pending JPS5513253A (en) 1978-07-15 1978-07-15 Cis-3-aralkyl substituted-8-benzoylthio-6,11-dimethyl-2,6- methano-1,2,3,4,5,6-hexahydro-3-benzazocine or its acid addition salt

Country Status (1)

Country Link
JP (1) JPS5513253A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002537393A (en) * 1999-02-23 2002-11-05 ベーリンガー インゲルハイム ファルマ コマンディトゲゼルシャフト Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzoazosin-10-ols, processes for their preparation and their use as drugs

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002537393A (en) * 1999-02-23 2002-11-05 ベーリンガー インゲルハイム ファルマ コマンディトゲゼルシャフト Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzoazosin-10-ols, processes for their preparation and their use as drugs

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