JPS55129256A - Antifungal compound - Google Patents
Antifungal compoundInfo
- Publication number
- JPS55129256A JPS55129256A JP2380079A JP2380079A JPS55129256A JP S55129256 A JPS55129256 A JP S55129256A JP 2380079 A JP2380079 A JP 2380079A JP 2380079 A JP2380079 A JP 2380079A JP S55129256 A JPS55129256 A JP S55129256A
- Authority
- JP
- Japan
- Prior art keywords
- solvent
- formula
- compound expressed
- antifungal compound
- halogenosalicylic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 229940121375 antifungal agent Drugs 0.000 title abstract 2
- 230000000843 anti-fungal effect Effects 0.000 title 1
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 3
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
- ZYMJQJYBEAGNCX-UHFFFAOYSA-N 5-bromo-n-(4-chloro-2-methylphenyl)-2-hydroxybenzamide Chemical compound CC1=CC(Cl)=CC=C1NC(=O)C1=CC(Br)=CC=C1O ZYMJQJYBEAGNCX-UHFFFAOYSA-N 0.000 abstract 1
- 241000233866 Fungi Species 0.000 abstract 1
- JLTDJTHDQAWBAV-UHFFFAOYSA-N N,N-dimethylaniline Chemical compound CN(C)C1=CC=CC=C1 JLTDJTHDQAWBAV-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000003429 antifungal agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000012188 paraffin wax Substances 0.000 abstract 1
- 238000001243 protein synthesis Methods 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 150000003512 tertiary amines Chemical class 0.000 abstract 1
- 230000014616 translation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
- A01N37/38—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system
- A01N37/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system having at least one carboxylic group or a thio analogue, or a derivative thereof, and one oxygen or sulfur atom attached to the same aromatic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2380079A JPS55129256A (en) | 1979-02-28 | 1979-02-28 | Antifungal compound |
| US06/123,655 US4310682A (en) | 1979-02-28 | 1980-02-22 | Halo-salicylanilide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2380079A JPS55129256A (en) | 1979-02-28 | 1979-02-28 | Antifungal compound |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS55129256A true JPS55129256A (en) | 1980-10-06 |
| JPS5726666B2 JPS5726666B2 (Direct) | 1982-06-05 |
Family
ID=12120388
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2380079A Granted JPS55129256A (en) | 1979-02-28 | 1979-02-28 | Antifungal compound |
Country Status (2)
| Country | Link |
|---|---|
| US (1) | US4310682A (Direct) |
| JP (1) | JPS55129256A (Direct) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014501763A (ja) * | 2010-12-22 | 2014-01-23 | ザ トラスティーズ オブ コロンビア ユニヴァーシティ イン ザ シティ オブ ニューヨーク | ヒストンアセチル基転移酵素モジュレーターおよびその使用 |
| US10640457B2 (en) | 2009-12-10 | 2020-05-05 | The Trustees Of Columbia University In The City Of New York | Histone acetyltransferase activators and uses thereof |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55102128U (Direct) * | 1979-01-10 | 1980-07-16 | ||
| JPS58181977U (ja) * | 1982-05-29 | 1983-12-05 | いすゞ自動車株式会社 | 内燃機関の燃料制御装置 |
| KR0143565B1 (ko) * | 1988-06-13 | 1998-07-15 | 사노 가즈오 | 피발산의 p-치환된 페닐 에스테르 유도체, 그의 제조 방법 및 이를 포함하는 조성물. |
| DE4428380A1 (de) * | 1994-08-11 | 1996-02-15 | Bayer Ag | 4-Trifluormethylbenzamide |
| GB0711957D0 (en) * | 2007-06-21 | 2007-08-01 | Syntopix Ltd | Formulations |
| RU2370484C1 (ru) * | 2008-04-02 | 2009-10-20 | Государственное образовательное учреждение высшего профессионального образования САНКТ-ПЕТЕРБУРГСКАЯ ГОСУДАРСТВЕННАЯ ХИМИКО-ФАРМАЦЕВТИЧЕСКАЯ АКАДЕМИЯ (ГОУ ВПО СПХФА Росздрава) | Антигельминтное средство на основе n-(3-хлор-4-метилфенил)-3,5-дибромсалициламида |
| RU2476424C1 (ru) * | 2011-12-22 | 2013-02-27 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Санкт-Петербургская государственная химико-фармацевтическая академия" Министерства здравоохранения и социального развития Российской Федерации (ГБОУ ВПО СПХФА Минздравсоцразвития России) | N-(3-хлор-4-пропилоксифенил)-3,5-дихлорсалициламид, обладающий антигельминтной активностью |
| ES2970434T3 (es) | 2014-09-12 | 2024-05-28 | Union Therapeutics As | Uso antibacteriano de salicilanilidas halogenadas |
| GB201509326D0 (en) | 2015-05-29 | 2015-07-15 | Antibio Tx Aps | Novel use |
| US11419834B2 (en) | 2019-02-25 | 2022-08-23 | Rhode Island Hospital | Methods for treating diseases or infections caused by or associated with H. pylori using a halogenated salicylanilide |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2703332A (en) * | 1955-03-01 | Poly halo-salicylanilioes | ||
| US2802029A (en) * | 1951-10-17 | 1957-08-06 | Knoll Ag | Bromsalicyloyl-chloranilide |
| US3147300A (en) * | 1955-09-26 | 1964-09-01 | Bayer Ag | Gastropod combating salicylanilides |
| NL255279A (Direct) * | 1959-08-27 | |||
| US3079297A (en) * | 1960-05-31 | 1963-02-26 | Bayer Ag | Method of combating gastropods |
| BE615511A (Direct) * | 1961-03-25 | |||
| DE2120862A1 (de) * | 1971-04-28 | 1972-11-09 | Farbenfabriken Bayer Ag, 5090 Leverkusen | 3,5-Disubstituierte 2-Acyloxybenzoesäureanilide, Verfahren zu ihrer Herstellung und ihre insektizide und akarizide Verwendung |
| US3839443A (en) * | 1971-10-04 | 1974-10-01 | Ferro Corp | Compounds of 2',4'-substituted anilides of substituted nitrosalicylic acid |
| US3906034A (en) * | 1972-03-21 | 1975-09-16 | Hoechst Ag | Trifluoromethyl-salicylanilides |
| US3927071A (en) * | 1972-05-12 | 1975-12-16 | Ici Australia Ltd | Salicylanilides |
| US3989826A (en) * | 1972-05-12 | 1976-11-02 | Ici Australia Limited | Method of killing internal parasites using salicylanilides |
-
1979
- 1979-02-28 JP JP2380079A patent/JPS55129256A/ja active Granted
-
1980
- 1980-02-22 US US06/123,655 patent/US4310682A/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10640457B2 (en) | 2009-12-10 | 2020-05-05 | The Trustees Of Columbia University In The City Of New York | Histone acetyltransferase activators and uses thereof |
| US11034647B2 (en) | 2009-12-10 | 2021-06-15 | The Trustees Of Columbia University In The City Of New York | Histone acetyltransferase activators and uses thereof |
| JP2014501763A (ja) * | 2010-12-22 | 2014-01-23 | ザ トラスティーズ オブ コロンビア ユニヴァーシティ イン ザ シティ オブ ニューヨーク | ヒストンアセチル基転移酵素モジュレーターおよびその使用 |
| US9969677B2 (en) | 2010-12-22 | 2018-05-15 | The Trustees Of Columbia University In The City Of New York | Histone acetyltransferase modulators and uses thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| US4310682A (en) | 1982-01-12 |
| JPS5726666B2 (Direct) | 1982-06-05 |
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