JPS55127373A - Tetrahydroisoquinoline compound and its preparation - Google Patents
Tetrahydroisoquinoline compound and its preparationInfo
- Publication number
- JPS55127373A JPS55127373A JP3579279A JP3579279A JPS55127373A JP S55127373 A JPS55127373 A JP S55127373A JP 3579279 A JP3579279 A JP 3579279A JP 3579279 A JP3579279 A JP 3579279A JP S55127373 A JPS55127373 A JP S55127373A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- tetrahydroisoquinoline
- alkyl
- preparation
- tetrahydroisoquinoline compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 Tetrahydroisoquinoline compound Chemical class 0.000 title abstract 2
- UWYZHKAOTLEWKK-UHFFFAOYSA-N tetrahydro-isoquinoline Natural products C1=CC=C2CNCCC2=C1 UWYZHKAOTLEWKK-UHFFFAOYSA-N 0.000 title abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- WZGWNBJURDGYPL-MYIOLCAUSA-N (3s)-2-(3-acetylsulfanyl-2-methylpropanoyl)-6,7-dihydroxy-3,4-dihydro-1h-isoquinoline-3-carboxylic acid Chemical compound OC1=C(O)C=C2C[C@@H](C(O)=O)N(C(=O)C(CSC(C)=O)C)CC2=C1 WZGWNBJURDGYPL-MYIOLCAUSA-N 0.000 abstract 1
- HTSGKJQDMSTCGS-UHFFFAOYSA-N 1,4-bis(4-chlorophenyl)-2-(4-methylphenyl)sulfonylbutane-1,4-dione Chemical compound C1=CC(C)=CC=C1S(=O)(=O)C(C(=O)C=1C=CC(Cl)=CC=1)CC(=O)C1=CC=C(Cl)C=C1 HTSGKJQDMSTCGS-UHFFFAOYSA-N 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000005530 alkylenedioxy group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- NLFBCYMMUAKCPC-KQQUZDAGSA-N ethyl (e)-3-[3-amino-2-cyano-1-[(e)-3-ethoxy-3-oxoprop-1-enyl]sulfanyl-3-oxoprop-1-enyl]sulfanylprop-2-enoate Chemical compound CCOC(=O)\C=C\SC(=C(C#N)C(N)=O)S\C=C\C(=O)OCC NLFBCYMMUAKCPC-KQQUZDAGSA-N 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
Landscapes
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3579279A JPS55127373A (en) | 1979-03-26 | 1979-03-26 | Tetrahydroisoquinoline compound and its preparation |
| AT80300933T ATE3546T1 (de) | 1979-03-26 | 1980-03-25 | Tetrahydroisochinolin-derivate, ihre herstellung und sie enthaltende pharmazeutische zusammensetzungen zur verwendung bei der vorbeugung und behandlung von erhoehtem blutdruck. |
| DE8080300933T DE3063420D1 (en) | 1979-03-26 | 1980-03-25 | Tetrahydroisoquinolines, their production and the compounds and pharmaceutical compositions containing them for use in the prevention or treatment of hypertension |
| EP19800300933 EP0018104B1 (en) | 1979-03-26 | 1980-03-25 | Tetrahydroisoquinolines, their production and the compounds and pharmaceutical compositions containing them for use in the prevention or treatment of hypertension |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3579279A JPS55127373A (en) | 1979-03-26 | 1979-03-26 | Tetrahydroisoquinoline compound and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS55127373A true JPS55127373A (en) | 1980-10-02 |
| JPS6338991B2 JPS6338991B2 (enrdf_load_stackoverflow) | 1988-08-03 |
Family
ID=12451761
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP3579279A Granted JPS55127373A (en) | 1979-03-26 | 1979-03-26 | Tetrahydroisoquinoline compound and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS55127373A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016525093A (ja) * | 2013-07-08 | 2016-08-22 | ノバルティス アーゲー | ヘテロ環式化合物およびそれらの使用方法 |
-
1979
- 1979-03-26 JP JP3579279A patent/JPS55127373A/ja active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016525093A (ja) * | 2013-07-08 | 2016-08-22 | ノバルティス アーゲー | ヘテロ環式化合物およびそれらの使用方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6338991B2 (enrdf_load_stackoverflow) | 1988-08-03 |
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