JPS55120579A - Production of delta-alkyl-delta-lactones - Google Patents
Production of delta-alkyl-delta-lactonesInfo
- Publication number
- JPS55120579A JPS55120579A JP2729279A JP2729279A JPS55120579A JP S55120579 A JPS55120579 A JP S55120579A JP 2729279 A JP2729279 A JP 2729279A JP 2729279 A JP2729279 A JP 2729279A JP S55120579 A JPS55120579 A JP S55120579A
- Authority
- JP
- Japan
- Prior art keywords
- reaction
- grignard reagent
- ester
- delta
- formylbutyric
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pyrane Compounds (AREA)
Abstract
PURPOSE: The reaction of γ-formylbutyric ester with a grignard reagent followed by lactonization under acidic conditions gives title compound useful as a flavor for dairy products from readily available starting materials in high yield.
CONSTITUTION: The reaction of γ-formylbutyric ester (A) with a grignard reagent of formula: RMgX (R is 3W9C straight chain alkyl; X is Cl, Br, I) is followed by hydrolysis and lactonization under acidic conditions to give the objective compound of the formula. The starting material A is obtained by conducting the Michael reaction between acrolein and malonic ester to form γ,γ-dicarboalkoxybutyraldehyde, which is heated together with a nonprotonic solvent (e.g., DMSO) containing water. In the reaction between the starting material A and the grignard reagent, the amount of A employed is a little in excess and ethyl ether is used as a solvent. The temperature is -30W30°C.
EFFECT: The operations are simple.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2729279A JPS55120579A (en) | 1979-03-09 | 1979-03-09 | Production of delta-alkyl-delta-lactones |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2729279A JPS55120579A (en) | 1979-03-09 | 1979-03-09 | Production of delta-alkyl-delta-lactones |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS55120579A true JPS55120579A (en) | 1980-09-17 |
Family
ID=12216997
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2729279A Pending JPS55120579A (en) | 1979-03-09 | 1979-03-09 | Production of delta-alkyl-delta-lactones |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55120579A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5248792A (en) * | 1991-05-15 | 1993-09-28 | Givaudan-Roure Corporation | 5-methyl-6-pentyl-tetrahydro-α-pyrone and analogs |
-
1979
- 1979-03-09 JP JP2729279A patent/JPS55120579A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5248792A (en) * | 1991-05-15 | 1993-09-28 | Givaudan-Roure Corporation | 5-methyl-6-pentyl-tetrahydro-α-pyrone and analogs |
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