JPS55114297A - Production of beta-lactam type antibiotic - Google Patents
Production of beta-lactam type antibioticInfo
- Publication number
- JPS55114297A JPS55114297A JP2101679A JP2101679A JPS55114297A JP S55114297 A JPS55114297 A JP S55114297A JP 2101679 A JP2101679 A JP 2101679A JP 2101679 A JP2101679 A JP 2101679A JP S55114297 A JPS55114297 A JP S55114297A
- Authority
- JP
- Japan
- Prior art keywords
- lactam type
- formula
- produce
- type antibiotic
- beta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PURPOSE: An optically inactive β-lactam type antibiotic is acylated by the action of a specific microorganism to produce an optically active β-lactam type biotic.
CONSTITUTION: The reaction between an acid of formula I (R is acyl group) or its reactive derivative and a chemically cynthesized d1-compound of formula II (Z is hydrocarbyl chain of 2 or 3 carbon atoms forming ring A of 5W6 member, in which one carbon may be replaced with oxygen or sulfur atom) is effected in the presence of the culture mixture of a microorganism belonging to Pseudomonas, Bacillus, Alcaligenes, Escherichia, Kluyveromyces or Proteus, e.g., Alcaligenes faecalis ATCC-25094 or its processed product to produce said optically active isomer of formula III.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2101679A JPS55114297A (en) | 1979-02-24 | 1979-02-24 | Production of beta-lactam type antibiotic |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2101679A JPS55114297A (en) | 1979-02-24 | 1979-02-24 | Production of beta-lactam type antibiotic |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS55114297A true JPS55114297A (en) | 1980-09-03 |
Family
ID=12043241
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2101679A Pending JPS55114297A (en) | 1979-02-24 | 1979-02-24 | Production of beta-lactam type antibiotic |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55114297A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4302541A (en) * | 1979-11-14 | 1981-11-24 | Kyowa Hakko Kogyo Co., Ltd. | Process of producing optically active cephalosporin analogs by enzyme selective deacylation |
US4302540A (en) * | 1979-10-25 | 1981-11-24 | Kyowa Hakko Kogyo Co., Ltd. | Process of producing optically active cephalosporin analogs by enzyme selective deacylation |
-
1979
- 1979-02-24 JP JP2101679A patent/JPS55114297A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4302540A (en) * | 1979-10-25 | 1981-11-24 | Kyowa Hakko Kogyo Co., Ltd. | Process of producing optically active cephalosporin analogs by enzyme selective deacylation |
US4302541A (en) * | 1979-11-14 | 1981-11-24 | Kyowa Hakko Kogyo Co., Ltd. | Process of producing optically active cephalosporin analogs by enzyme selective deacylation |
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