JPS545981A - Carbostyryl derivatives - Google Patents

Carbostyryl derivatives

Info

Publication number
JPS545981A
JPS545981A JP6931977A JP6931977A JPS545981A JP S545981 A JPS545981 A JP S545981A JP 6931977 A JP6931977 A JP 6931977A JP 6931977 A JP6931977 A JP 6931977A JP S545981 A JPS545981 A JP S545981A
Authority
JP
Japan
Prior art keywords
carbostyryl derivatives
carbostyryl
substd
phenyl
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6931977A
Other languages
English (en)
Other versions
JPS6113470B2 (ja
Inventor
Takao Nishi
Takashi Ueda
Kazuyuki Nakagawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP6931977A priority Critical patent/JPS545981A/ja
Priority to IE1104/78A priority patent/IE46852B1/en
Priority to NZ187452A priority patent/NZ187452A/xx
Priority to ZA00783202A priority patent/ZA783202B/xx
Priority to AU36866/78A priority patent/AU510138B2/en
Priority to FI781811A priority patent/FI69300C/fi
Priority to DE19782825048 priority patent/DE2825048A1/de
Priority to FR7817167A priority patent/FR2393795B1/fr
Priority to DK254878A priority patent/DK149449C/da
Priority to NLAANVRAGE7806245,A priority patent/NL178074C/xx
Priority to ES470690A priority patent/ES470690A1/es
Priority to PH21245A priority patent/PH14670A/en
Priority to AR272511A priority patent/AR224345A1/es
Priority to SE7806710A priority patent/SE444562B/sv
Priority to AT0421378A priority patent/AT367038B/de
Priority to PT68157A priority patent/PT68157A/pt
Priority to NO782022A priority patent/NO148813C/no
Priority to GB7826613A priority patent/GB2002745B/en
Priority to MX787136U priority patent/MX5527E/es
Priority to BE188479A priority patent/BE868004A/fr
Priority to MX797278A priority patent/MX156296A/es
Priority to CH632578A priority patent/CH636087A5/de
Priority to CA305,102A priority patent/CA1098907A/en
Priority to IT68355/78A priority patent/IT1108326B/it
Publication of JPS545981A publication Critical patent/JPS545981A/ja
Priority to ES479138A priority patent/ES479138A1/es
Priority to AR279858A priority patent/AR225755A1/es
Priority to US06/142,057 priority patent/US4298739A/en
Priority to AT6481A priority patent/AT367039B/de
Publication of JPS6113470B2 publication Critical patent/JPS6113470B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP6931977A 1977-06-10 1977-06-10 Carbostyryl derivatives Granted JPS545981A (en)

Priority Applications (28)

Application Number Priority Date Filing Date Title
JP6931977A JPS545981A (en) 1977-06-10 1977-06-10 Carbostyryl derivatives
IE1104/78A IE46852B1 (en) 1977-06-10 1978-06-01 Novel carbostyril derivatives
NZ187452A NZ187452A (en) 1977-06-10 1978-06-01 N- substituted-aminocarbonylpropoxy-carbostyrils and their preparation
ZA00783202A ZA783202B (en) 1977-06-10 1978-06-05 Novel carbostyril derivatives
AU36866/78A AU510138B2 (en) 1977-06-10 1978-06-06 Carbostyril derivatives
FI781811A FI69300C (fi) 1977-06-10 1978-06-07 Foerfarande foer framstaellning av terapeutiskt anvaendbara ny karbostyrilderivat
DE19782825048 DE2825048A1 (de) 1977-06-10 1978-06-07 Neue carbostyrilderivate und verfahren zu deren herstellung
FR7817167A FR2393795B1 (fr) 1977-06-10 1978-06-08 Derives de carbostyryle, leur procede de preparation et leurs applications en therapeutique
DK254878A DK149449C (da) 1977-06-10 1978-06-08 Analogifremgangsmaade til fremstilling af carbostyrilderivater eller farmaceutisk acceptable salte deraf
NLAANVRAGE7806245,A NL178074C (nl) 1977-06-10 1978-06-08 Geneeskrachtige preparaten met een remmende werking op de aggregatie van bloedplaatjes en op de fosfodiesterase, alsmede in deze preparaten te gebruiken carbostyrilderivaten.
PT68157A PT68157A (en) 1977-06-10 1978-06-09 Novel carbo styril derivatives
CH632578A CH636087A5 (de) 1977-06-10 1978-06-09 Carbostyrilderivate und verfahren zu ihrer herstellung.
AR272511A AR224345A1 (es) 1977-06-10 1978-06-09 Procedimiento para obtener compuestos de 3-(n,n-disustituido amino)-carbonil-alcoxicarboestirilo y 3,4-dihidrocarboestirilo
SE7806710A SE444562B (sv) 1977-06-10 1978-06-09 Nya karbostyrilderivat
AT0421378A AT367038B (de) 1977-06-10 1978-06-09 Verfahren zum herstellen neuer carbostyrilderivate
ES470690A ES470690A1 (es) 1977-06-10 1978-06-09 Un procedimiento para la produccion de nuevos derivados car-bostirilicos
NO782022A NO148813C (no) 1977-06-10 1978-06-09 Analogifremgangsmaate for fremstilling av farmakologisk aktive karbostyrilderivater
GB7826613A GB2002745B (en) 1977-06-10 1978-06-09 Carbostyril derivatives
MX787136U MX5527E (es) 1977-06-10 1978-06-09 Procedimiento para la preparacion de derivados de carboestirilo
BE188479A BE868004A (fr) 1977-06-10 1978-06-09 Derives de carbostyryle, leur procede de preparation et leurs applications en therapeutique
MX797278A MX156296A (es) 1977-06-10 1978-06-09 Procedimiento para la preparacion de derivados de carboestirilo
PH21245A PH14670A (en) 1977-06-10 1978-06-09 Carbostyril derivatives
CA305,102A CA1098907A (en) 1977-06-10 1978-06-09 Carbostyril derivatives
IT68355/78A IT1108326B (it) 1977-06-10 1978-06-09 Carbostiril derivati particolarmente utili in medicina e procedimento per la loro preparazione
ES479138A ES479138A1 (es) 1977-06-10 1979-03-30 Un procedimiento para la produccion de nuevos derivados car-bostirilicos.
AR279858A AR225755A1 (es) 1977-06-10 1980-02-05 Procedimiento para obtener derivados de aminocarbonilalcoxi-carboestirilo o de 3,4-dihidro-carboestirilo
US06/142,057 US4298739A (en) 1977-06-10 1980-04-21 Novel carbostyril derivatives
AT6481A AT367039B (de) 1977-06-10 1981-01-09 Verfahren zum herstellen neuer carbostyrilderivate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6931977A JPS545981A (en) 1977-06-10 1977-06-10 Carbostyryl derivatives

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP57121547A Division JPS6010008B2 (ja) 1982-07-12 1982-07-12 血小板凝集抑制剤

Publications (2)

Publication Number Publication Date
JPS545981A true JPS545981A (en) 1979-01-17
JPS6113470B2 JPS6113470B2 (ja) 1986-04-14

Family

ID=13399107

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6931977A Granted JPS545981A (en) 1977-06-10 1977-06-10 Carbostyryl derivatives

Country Status (3)

Country Link
JP (1) JPS545981A (ja)
BE (1) BE868004A (ja)
ZA (1) ZA783202B (ja)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56122356A (en) * 1980-02-29 1981-09-25 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPS57175168A (en) * 1981-04-17 1982-10-28 Otsuka Pharmaceut Co Ltd Carbostyril derivative
WO1989010919A1 (en) 1988-05-02 1989-11-16 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
WO1993004042A1 (fr) * 1991-08-23 1993-03-04 Otsuka Pharmaceutical Co., Ltd. Derive de carbostyrile et antiagregant plaquettaire
JP2015199748A (ja) * 2009-08-21 2015-11-12 大塚製薬株式会社 窒素含有化合物及び医薬組成物

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56122356A (en) * 1980-02-29 1981-09-25 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPS6334845B2 (ja) * 1980-02-29 1988-07-12 Otsuka Pharma Co Ltd
JPS57175168A (en) * 1981-04-17 1982-10-28 Otsuka Pharmaceut Co Ltd Carbostyril derivative
WO1989010919A1 (en) 1988-05-02 1989-11-16 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
JPH0249768A (ja) * 1988-05-02 1990-02-20 Otsuka Pharmaceut Co Ltd カルボスチリル誘導体
WO1993004042A1 (fr) * 1991-08-23 1993-03-04 Otsuka Pharmaceutical Co., Ltd. Derive de carbostyrile et antiagregant plaquettaire
US5506239A (en) * 1991-08-23 1996-04-09 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivative and platelets aggregation inhibitory agent
US5658926A (en) * 1991-08-23 1997-08-19 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivative and platelets aggregation inhibitory agent
JP2015199748A (ja) * 2009-08-21 2015-11-12 大塚製薬株式会社 窒素含有化合物及び医薬組成物

Also Published As

Publication number Publication date
ZA783202B (en) 1979-10-31
BE868004A (fr) 1978-12-11
JPS6113470B2 (ja) 1986-04-14

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