JPS543090A - Novel derivative of cephalosporin compound and its preparation - Google Patents
Novel derivative of cephalosporin compound and its preparationInfo
- Publication number
- JPS543090A JPS543090A JP6869977A JP6869977A JPS543090A JP S543090 A JPS543090 A JP S543090A JP 6869977 A JP6869977 A JP 6869977A JP 6869977 A JP6869977 A JP 6869977A JP S543090 A JPS543090 A JP S543090A
- Authority
- JP
- Japan
- Prior art keywords
- preparation
- cephalosporin compound
- novel derivative
- derivative
- novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229930186147 Cephalosporin Natural products 0.000 title abstract 2
- 229940124587 cephalosporin Drugs 0.000 title abstract 2
- -1 cephalosporin compound Chemical class 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001780 cephalosporins Chemical class 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (33)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP52068699A JPS5854157B2 (ja) | 1977-06-10 | 1977-06-10 | セフアロスポリン化合物の新規誘導体ならびにその製造方法 |
GB24853/80A GB1604740A (en) | 1977-06-10 | 1978-05-31 | 7-isothiazolylthioacetamido-7-methoxycephalosporanic acid derivatives |
CH6107/78A CH648317A5 (de) | 1977-06-10 | 1978-06-05 | 7alpha-methoxy-7betha-(1,3-dithietan-2- carboxamido)cephalosporansaeurederivate und verfahren zu ihrer herstellung. |
DE2857816A DE2857816C2 (de) | 1977-06-10 | 1978-06-05 | 7ß-(substituierte-Isothiazol)thioacetamido-7-methoxy(alkylsubstituierte-tetraz olyl)thiomethyl-Δ↑3↑-cephem-4-carbonsäuren, Verfahren zu ihrer Herstellung und deren Verwendung |
DE2824559A DE2824559C2 (de) | 1977-06-10 | 1978-06-05 | 7α-Methoxy-7β-(4-substituierte-methylen-1,3-dithietan-2-yl)-carboxamido-3-Δ↑3↑-cephem-4-carbonsäuren, Verfahren zu deren Herstellung sowie ihre Verwendung |
US05/913,500 US4263432A (en) | 1977-06-10 | 1978-06-07 | 7α-Methoxy-7β-(1,3-dithietane-2-carboxamido)cephalosporanic acid derivatives |
NLAANVRAGE7806208,A NL185622C (nl) | 1977-06-10 | 1978-06-07 | Farmaceutisch preparaat met antibacteriele werking, alsmede 7beta-acylamino-7alfa-methoxy-3-heterocyclylthiomethyl-3-cefem-4-carbonzuur. |
CA305,045A CA1103659A (en) | 1977-06-10 | 1978-06-08 | PROCESS FOR THE PREPARATION OF 7.alpha.-METHOXY-7.beta.-(1,3- DITHIETANE-2-CARBOXAMIDO)CEPHALOSPORANIC ACID DERIVATIVES |
SE7806711A SE438338B (sv) | 1977-06-10 | 1978-06-09 | 7alfa-metoxi-7beta-(1,3-ditietan-2-karboxamido)-cefalosporansyraderivat med antibakteriell verkan |
AU36988/78A AU518620B2 (en) | 1977-06-10 | 1978-06-09 | 7d-methoxy-7b-(1,3-dithietane-2-carboxamido)cephalosporanic acid derivatives |
ES470689A ES470689A1 (es) | 1977-06-10 | 1978-06-09 | Un procedimiento para la preparacion de acido 7-metoxi-7- (4-metilen sustituido-1,3-ditietan-2-il-carboxamido)-3-hete-rociclotiometil-3-cefem-4-carboxilico |
FR7817303A FR2405952A1 (fr) | 1977-06-10 | 1978-06-09 | Derives de l'acide methoxy-7a-(dithietane-1,3-carboxamido-2)-cephalosporanique, presentant une activite anti-bacterienne et leurs procedes de preparation |
DK258078A DK164224C (da) | 1977-06-10 | 1978-06-09 | Analogifremgangsmaade til fremstilling af 7alfa-methoxy-7beta-(4-methylen-1,3-dithietan-2-yl)carboxamido-3-heterocyclylthiomethyl-delta3-cephem-4-carboxylsyre-forbindelser eller salte deraf og mellemprodukter til anvendelse herved |
HU801504A HU184788B (en) | 1977-06-10 | 1978-06-09 | Process for the preparation of 7alfa-methoxy-ceph-3-em-4-carboxylic acid derivatives |
BE188469A BE867994A (fr) | 1977-06-10 | 1978-06-09 | Procede de preparation de derives de l'acide methoxy-7,alpha-(dithietane-1,3-carboxamido-2)-cephalosporanique |
MX787141U MX5137E (es) | 1977-06-10 | 1978-06-12 | Procedimiento para la preparacion del acido tio-metil-delta3-cefem-carboxilico,7 alfa metoxi-7 beta(metilen-1,3-ditietan-2-il-carboxamido-4-substituido)-3-heterociclico |
MX1051378U MX7170E (es) | 1977-06-10 | 1978-06-12 | Procedimiento para la preparacion del acido tiometil-delta3-cefem-4-carboxilico,7 alfa-metoxi-7beta-(metilen-1,3-ditietan-2-il 4-substituido)-carboxamido-3-heterociclico |
MX1051478U MX7171E (es) | 1977-06-10 | 1978-06-12 | Procedimiento para la preparacion del acido tio-metil-delta3-cefem-4-carboxilico,7alfa-metoxi-7beta-(metilen-1,3-ditietan-2-il,4-substituido)carboxamido-3-heterociclico |
IT68369/78A IT1159721B (it) | 1977-06-10 | 1978-06-12 | Derivati dell'acido 7 alfa metossi-7 beta-(1,3-ditietane-2-carbossiamido)-cefalosporanico e procedimento per la loro preparazione |
FR7834349A FR2405953A1 (fr) | 1977-06-10 | 1978-12-06 | Derives de la methoxy-7a-thiomethylheterocyclique-3-cephalosporine representant une activite anti-bacterienne |
ES479167A ES479167A1 (es) | 1977-06-10 | 1979-03-31 | Un procedimiento para la preparacion de acido 7&-metoxi-7b( 4-metilen sustituido-1,3-ditietan-2-il)carboxamido-3-hete- ro-ciclotiometil-3-cefem-4-carboxilico. |
ES479168A ES479168A1 (es) | 1977-06-10 | 1979-03-31 | Un procedimiento para la preparacion de derivados de acido 7&-metoxicefalosporanico. |
ES479166A ES479166A1 (es) | 1977-06-10 | 1979-03-31 | Un procedimiento para la preparacion de acido 7&-metoxi-7b-(4-metilen sustituido 1,3-ditietan-2il) carboxamido-3-hetero-ciclotiometil-3-cefem-4-carboxilico. |
UA2781814A UA5924A1 (uk) | 1977-06-10 | 1979-06-25 | СПОСІБ ОДЕРЖАННЯ 7alРha-МЕТОКСІЦЕФАЛОСПОРІНІВ |
SU792781814A SU843752A3 (ru) | 1977-06-10 | 1979-06-25 | Способ получени -метоксицефало-СпОРиНОВ |
AT0685679A AT363187B (de) | 1977-06-10 | 1979-10-22 | Verfahren zur herstellung von neuen 7alpha-methoxycephalosporansaeurederivaten |
SU802893654A SU904525A3 (ru) | 1977-06-10 | 1980-03-11 | Способ получени 7 @ -метоксицефалоспоринов |
UA2893654A UA5922A1 (uk) | 1977-06-10 | 1980-03-11 | СПОСІБ ОДЕРЖАННЯ 7alРha-МЕТОКСІЦЕФАЛОСПОРІНІВ |
AT345780A AT367062B (de) | 1977-06-10 | 1980-07-02 | Verfahren zur herstellung von neuen 7alphamethoxy-cephalosporansaeurederivaten |
US06/208,298 US4404373A (en) | 1977-06-10 | 1980-11-19 | Process for the preparation of 7α-methoxy-7β-(1,3-diethietane-2-carboxamido)cephalosporanic acid derivatives |
SE8306298A SE454512B (sv) | 1977-06-10 | 1983-11-16 | 7beta-isotiazolyltioacetamido-7alfa-metoxicefalosporansyraderivat |
US06/727,233 USRE32491E (en) | 1977-06-10 | 1985-04-25 | Process for the preparation of 7α-methoxy-7β-(1,3-diethietane-2-carboxyamido)cephalosporanic acid derivatives |
NL8901120A NL8901120A (nl) | 1977-06-10 | 1989-05-02 | Farmaceutisch preparaat met anti-bacteriele werking alsmede 7beta-acylamino 7alfa-methoxy-3-heterocyclylthiomethyl-3-cefem-4-carbonzuur. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP52068699A JPS5854157B2 (ja) | 1977-06-10 | 1977-06-10 | セフアロスポリン化合物の新規誘導体ならびにその製造方法 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP17426082A Division JPS5850206B2 (ja) | 1982-10-04 | 1982-10-04 | セフアロスポリン化合物の新規誘導体 |
JP9035283A Division JPS603399B2 (ja) | 1983-05-23 | 1983-05-23 | セファロスポリン化合物の新規な誘導体 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS543090A true JPS543090A (en) | 1979-01-11 |
JPS5854157B2 JPS5854157B2 (ja) | 1983-12-02 |
Family
ID=13381266
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP52068699A Expired JPS5854157B2 (ja) | 1977-06-10 | 1977-06-10 | セフアロスポリン化合物の新規誘導体ならびにその製造方法 |
Country Status (10)
Country | Link |
---|---|
JP (1) | JPS5854157B2 (ja) |
AU (1) | AU518620B2 (ja) |
BE (1) | BE867994A (ja) |
DE (1) | DE2857816C2 (ja) |
FR (1) | FR2405953A1 (ja) |
GB (1) | GB1604740A (ja) |
HU (1) | HU184788B (ja) |
SE (1) | SE454512B (ja) |
SU (2) | SU843752A3 (ja) |
UA (2) | UA5924A1 (ja) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0187355A1 (en) | 1981-09-23 | 1986-07-16 | E.R. Squibb & Sons, Inc. | Process for preparing beta-lactam antibiotics |
ZA874696B (en) | 1986-07-03 | 1988-01-04 | F. Hoffmann-La Roche & Co. Aktiengesellschaft | Acyl derivatives |
EP0620225B1 (en) | 1993-04-16 | 2002-11-13 | Basilea Pharmaceutica AG | Cephalosporin derivatives |
US5811419A (en) * | 1996-01-16 | 1998-09-22 | Hoffmann-La Roche Inc. | Isooxacephem-derivatives |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2552861A1 (de) * | 1974-11-30 | 1976-06-10 | Sankyo Co | Verfahren zur herstellung von 7-methoxycephalosporinverbindungen |
DE2625015A1 (de) * | 1975-09-16 | 1976-12-30 | Fujisawa Pharmaceutical Co | 3-substituierte-7-substituiertealkanamido-3-cephem-4-carbonsaeure-verbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL29235A (en) * | 1967-01-05 | 1971-10-20 | Bristol Myers Co | 7-(pyridylthioacetamido)cephalosporanic acid derivatives and their preparation |
DE2539214C2 (de) * | 1975-09-03 | 1984-03-29 | E.R. Squibb & Sons, Inc., 08540 Princeton, N.J. | 7-Methoxythienyl-ureido-cephalosporin und dieses enthaltendes Arzneimittel |
-
1977
- 1977-06-10 JP JP52068699A patent/JPS5854157B2/ja not_active Expired
-
1978
- 1978-05-31 GB GB24853/80A patent/GB1604740A/en not_active Expired
- 1978-06-05 DE DE2857816A patent/DE2857816C2/de not_active Expired
- 1978-06-09 AU AU36988/78A patent/AU518620B2/en not_active Expired
- 1978-06-09 HU HU801504A patent/HU184788B/hu unknown
- 1978-06-09 BE BE188469A patent/BE867994A/xx not_active IP Right Cessation
- 1978-12-06 FR FR7834349A patent/FR2405953A1/fr active Granted
-
1979
- 1979-06-25 UA UA2781814A patent/UA5924A1/uk unknown
- 1979-06-25 SU SU792781814A patent/SU843752A3/ru active
-
1980
- 1980-03-11 UA UA2893654A patent/UA5922A1/uk unknown
- 1980-03-11 SU SU802893654A patent/SU904525A3/ru active
-
1983
- 1983-11-16 SE SE8306298A patent/SE454512B/sv not_active IP Right Cessation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2552861A1 (de) * | 1974-11-30 | 1976-06-10 | Sankyo Co | Verfahren zur herstellung von 7-methoxycephalosporinverbindungen |
DE2625015A1 (de) * | 1975-09-16 | 1976-12-30 | Fujisawa Pharmaceutical Co | 3-substituierte-7-substituiertealkanamido-3-cephem-4-carbonsaeure-verbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel |
Also Published As
Publication number | Publication date |
---|---|
SE454512B (sv) | 1988-05-09 |
DE2857816C2 (de) | 1985-05-09 |
AU518620B2 (en) | 1981-10-08 |
SE8306298L (sv) | 1983-11-16 |
SE8306298D0 (sv) | 1983-11-16 |
GB1604740A (en) | 1981-12-16 |
BE867994A (fr) | 1978-12-11 |
HU184788B (en) | 1984-10-29 |
AU3698878A (en) | 1979-12-13 |
FR2405953A1 (fr) | 1979-05-11 |
JPS5854157B2 (ja) | 1983-12-02 |
FR2405953B1 (ja) | 1983-07-18 |
SU904525A3 (ru) | 1982-02-07 |
SU843752A3 (ru) | 1981-06-30 |
UA5924A1 (uk) | 1994-12-29 |
UA5922A1 (uk) | 1994-12-29 |
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