JPS5416423A - Alphaafluoromethyllalphaaaminoalkanoate - Google Patents

Alphaafluoromethyllalphaaaminoalkanoate

Info

Publication number
JPS5416423A
JPS5416423A JP6501678A JP6501678A JPS5416423A JP S5416423 A JPS5416423 A JP S5416423A JP 6501678 A JP6501678 A JP 6501678A JP 6501678 A JP6501678 A JP 6501678A JP S5416423 A JPS5416423 A JP S5416423A
Authority
JP
Japan
Prior art keywords
alphaafluoromethyllalphaaaminoalkanoate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6501678A
Other languages
English (en)
Japanese (ja)
Other versions
JPS641474B2 (hu
Inventor
Koronitsushiyu Jiyanosu
Maaruburugu Sutefuen
Aran Pachietsuto Aasaa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/802,391 external-priority patent/US4325961A/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of JPS5416423A publication Critical patent/JPS5416423A/ja
Publication of JPS641474B2 publication Critical patent/JPS641474B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
JP6501678A 1977-06-01 1978-06-01 Alphaafluoromethyllalphaaaminoalkanoate Granted JPS5416423A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80238977A 1977-06-01 1977-06-01
US05/802,391 US4325961A (en) 1977-06-01 1977-06-01 Fluorinated amino acids

Publications (2)

Publication Number Publication Date
JPS5416423A true JPS5416423A (en) 1979-02-07
JPS641474B2 JPS641474B2 (hu) 1989-01-11

Family

ID=27122442

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6501678A Granted JPS5416423A (en) 1977-06-01 1978-06-01 Alphaafluoromethyllalphaaaminoalkanoate

Country Status (26)

Country Link
JP (1) JPS5416423A (hu)
AR (1) AR223463A1 (hu)
AT (1) AT360509B (hu)
AU (1) AU518479B2 (hu)
CA (1) CA1120040A (hu)
CH (1) CH639639A5 (hu)
DD (1) DD138651A5 (hu)
DE (1) DE2824116A1 (hu)
DK (1) DK149841C (hu)
ES (1) ES470296A1 (hu)
FI (1) FI66840C (hu)
FR (1) FR2392958A1 (hu)
GB (1) GB1602525A (hu)
GR (1) GR64495B (hu)
HK (1) HK18184A (hu)
HU (1) HU181911B (hu)
IE (1) IE46983B1 (hu)
IT (1) IT1104709B (hu)
LU (1) LU79750A1 (hu)
NL (1) NL190485C (hu)
NO (1) NO147382C (hu)
NZ (1) NZ187377A (hu)
PL (1) PL115731B1 (hu)
PT (1) PT68102B (hu)
SE (1) SE7806440L (hu)
YU (1) YU129178A (hu)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55145647A (en) * 1979-04-26 1980-11-13 Merrell Toraude & Co Alphaahalomethylamino acids
JPS5777648A (en) * 1980-05-09 1982-05-15 Merrell Toraude & Co Fluoromethylated tyrosine methyl ester

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1091661A (en) * 1977-07-11 1980-12-16 Philippe Bey .alpha.-HALOMETHYL DERIVATIVES OF .alpha.-AMINO ACIDS
ZA783273B (en) * 1977-07-11 1979-06-27 Merrell Toraude & Co A-halomethyl amino acids
IL59481A0 (en) * 1977-07-11 1980-05-30 Merrell Toraude & Co -halomethyl amino acids
US4315095A (en) * 1977-07-28 1982-02-09 Merrell Toraude Et Compagnie α-Halomethyl derivatives of amino acids
EP0007600B1 (en) * 1978-07-24 1983-05-11 Merck & Co. Inc. Alpha-difluoromethyl amino acids and pharmaceutical composition containing the same
NZ194347A (en) * 1979-07-26 1982-11-23 Merrell Toraude & Co Fluorinated alkenylamines intermediate alkenyl fluorinated methyl ketimine magnesium halides and preparation of certain amino alkanoic acids
AU544990B2 (en) * 1980-06-16 1985-06-27 Merrell Pharmaceuticals Inc. Antiprotozal composition containing amino compounds
US4421767A (en) * 1981-06-01 1983-12-20 Merrell Toraude Et Compagnie Compounds and methods for treating depression
GB9325368D0 (en) * 1993-12-10 1994-02-16 Univ Bristol Organic compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3046300A (en) * 1960-10-21 1962-07-24 Merck & Co Inc alpha-trifluoromethyloxyphenylalanines

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55145647A (en) * 1979-04-26 1980-11-13 Merrell Toraude & Co Alphaahalomethylamino acids
JPS5777648A (en) * 1980-05-09 1982-05-15 Merrell Toraude & Co Fluoromethylated tyrosine methyl ester
JPH0335310B2 (hu) * 1980-05-09 1991-05-27 Merrell Toraude & Co

Also Published As

Publication number Publication date
NO781892L (no) 1978-12-04
PL115731B1 (en) 1981-04-30
GB1602525A (en) 1981-11-11
IT1104709B (it) 1985-10-28
AT360509B (de) 1981-01-12
NO147382C (no) 1983-03-30
ATA393278A (de) 1980-06-15
DK149841C (da) 1987-04-21
AU518479B2 (en) 1981-10-01
HU181911B (en) 1983-11-28
FI66840B (fi) 1984-08-31
FR2392958A1 (fr) 1978-12-29
NL190485B (nl) 1993-10-18
LU79750A1 (fr) 1979-02-02
SE7806440L (sv) 1978-12-02
JPS641474B2 (hu) 1989-01-11
PL207242A1 (pl) 1979-04-23
NL190485C (nl) 1994-03-16
AR223463A1 (es) 1981-08-31
IT7849637A0 (it) 1978-05-31
DK237978A (da) 1979-01-19
PT68102B (en) 1982-06-08
IE46983B1 (en) 1983-11-16
NL7805981A (nl) 1978-12-05
FI781674A (fi) 1978-12-02
NO147382B (no) 1982-12-20
ES470296A1 (es) 1979-09-16
DE2824116C2 (hu) 1989-04-27
PT68102A (en) 1978-06-01
CH639639A5 (en) 1983-11-30
HK18184A (en) 1984-03-09
DK149841B (da) 1986-10-13
DD138651A5 (de) 1979-11-14
FR2392958B1 (hu) 1980-10-24
DE2824116A1 (de) 1978-12-14
NZ187377A (en) 1981-05-15
GR64495B (en) 1980-03-31
IE781078L (en) 1978-12-01
YU129178A (en) 1983-01-21
CA1120040A (en) 1982-03-16
AU3658678A (en) 1979-12-06
FI66840C (fi) 1984-12-10

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