JPS5049288A - Shinkina pirimijinkagobutsuno seizohoho - Google Patents

Shinkina pirimijinkagobutsuno seizohoho

Info

Publication number
JPS5049288A
JPS5049288A JP49094899A JP9489974A JPS5049288A JP S5049288 A JPS5049288 A JP S5049288A JP 49094899 A JP49094899 A JP 49094899A JP 9489974 A JP9489974 A JP 9489974A JP S5049288 A JPS5049288 A JP S5049288A
Authority
JP
Japan
Prior art keywords
shinkina
pirimijinkagobutsuno
seizohoho
shinkina pirimijinkagobutsuno
pirimijinkagobutsuno seizohoho
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP49094899A
Other languages
English (en)
Inventor
Naaru Berutoruto
Rotsuho Yozefu
Myuraa Eeritsuhi
Haaruman Barutaa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of JPS5049288A publication Critical patent/JPS5049288A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A63—SPORTS; GAMES; AMUSEMENTS
    • A63C—SKATES; SKIS; ROLLER SKATES; DESIGN OR LAYOUT OF COURTS, RINKS OR THE LIKE
    • A63C19/00—Design or layout of playing courts, rinks, bowling greens or areas for water-skiing; Covers therefor
    • A63C19/02—Shaping of the surface of courts according to the necessities of the different games

Landscapes

  • Engineering & Computer Science (AREA)
  • Architecture (AREA)
  • Civil Engineering (AREA)
  • Structural Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP49094899A 1973-08-20 1974-08-19 Shinkina pirimijinkagobutsuno seizohoho Pending JPS5049288A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732341925 DE2341925A1 (de) 1973-08-20 1973-08-20 Neue pyrimidinderivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
JPS5049288A true JPS5049288A (en) 1975-05-01

Family

ID=5890167

Family Applications (1)

Application Number Title Priority Date Filing Date
JP49094899A Pending JPS5049288A (en) 1973-08-20 1974-08-19 Shinkina pirimijinkagobutsuno seizohoho

Country Status (4)

Country Link
JP (1) JPS5049288A (ja)
BE (1) BE818990A (ja)
DE (1) DE2341925A1 (ja)
ZA (1) ZA745305B (ja)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57122082A (en) * 1980-12-11 1982-07-29 Bristol Myers Co Buspirone manufacture
WO2005085212A1 (ja) * 2004-03-04 2005-09-15 Astellas Pharma Inc. 置換ピリミジン誘導体
JP2006514118A (ja) * 2002-11-21 2006-04-27 カイロン コーポレイション ホスホチジルイノシトール（ｐｉ）３−キナーゼインヒビターとしての２，４，６−三置換ピリミジン、および癌の処置におけるその使用
JP2006516572A (ja) * 2003-01-14 2006-07-06 アリーナ ファーマシューティカルズ， インコーポレイテッド 代謝モジュレーターとしての１，２，３−トリ置換アリール誘導体および１，２，３−トリ置換ヘテロアリール誘導体ならびにこれらの誘導体に関連する糖尿病および高血糖のような障害の予防および処置
JP2007522197A (ja) * 2004-02-10 2007-08-09 サノフイ−アベンテイス オレキシン受容体アンタゴニストとしてのピリミジン誘導体
JP2008546731A (ja) * 2005-06-23 2008-12-25 ノバルティス アクチエンゲゼルシャフト Ｇａｂａｂ仲介神経系障害の処置のためのピリミジン誘導体
WO2009123221A1 (ja) * 2008-03-31 2009-10-08 全薬工業株式会社 細胞保護作用を有するピリミジン誘導体およびその用途
JP2014208692A (ja) * 2008-12-09 2014-11-06 ギリアード サイエンシーズ， インコーポレイテッド Ｔｏｌｌ様受容体のモジュレーター

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JPH0635450B2 (ja) * 1984-03-16 1994-05-11 三井東圧化学株式会社 チオシアノピリミジン誘導体、その製造法および農園芸用殺菌剤
US5098902A (en) * 1991-03-18 1992-03-24 Warner-Lambert Company Method of treating neurodegenerative diseases
US5075305A (en) * 1991-03-18 1991-12-24 Warner-Lambert Company Compound, composition and use
KR950703535A (ko) * 1992-09-18 1995-09-20 유미꾸라 레이이찌 아제핀 유도체, 그의 제조방법 및 용도(azepine derivative, production thereof, and use thereof)
US5658923A (en) * 1992-09-18 1997-08-19 Asahi Kasei Kogyo Kabushiki Kaisha Azepine derivatives and use thereof
CA2208900C (en) * 1996-07-18 2006-08-01 Lonza Ag Process for preparing 2-pyrimidinecarboxylates
BR9908004A (pt) 1998-02-17 2001-12-18 Tularik Inc Composto, composição e método para prevençãoou supressão de uma infecção viral
US6410726B1 (en) 2000-01-12 2002-06-25 Tularik Inc. Arylsulfonic acid salts of pyrimidine-based antiviral
SI1599468T1 (sl) * 2003-01-14 2008-02-29 Arena Pharm Inc 1,2,3-trisubstituirani arilni in heteroarilni derivati kot modulatorji metabolizma ter profilaksa in zdravljenje motenj v zvezi z njim, kot diabetesain hiperglikemije
AR045010A1 (es) * 2003-07-02 2005-10-12 Vertex Pharma Pirimidinas utiles como moduladores de canales ionicos cuya activacion es controlada por tension
AR045047A1 (es) 2003-07-11 2005-10-12 Arena Pharm Inc Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
EP2316827B1 (en) 2003-07-30 2016-01-27 Xenon Pharmaceuticals Inc. Piperazine derivatives and their use as therapeutic agents
RU2006105717A (ru) * 2003-07-30 2007-09-20 Зинон Фармасьютиклз Инк. (Ca) Производные пиперазина и их применение в качестве терапевтических агентов
CN101084212A (zh) 2004-09-20 2007-12-05 泽农医药公司 杂环衍生物及其作为硬脂酰CoA去饱和酶介导剂的用途
JP5149009B2 (ja) 2004-09-20 2013-02-20 ゼノン・ファーマシューティカルズ・インコーポレイテッド ヒトステアロイル−ＣｏＡデサチュラーゼを阻害するためのピリダジン誘導体
AU2005286793A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-CoA desaturase enzymes
EP1807085B1 (en) 2004-09-20 2013-08-21 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
CA2580857A1 (en) 2004-09-20 2006-09-28 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
CN101084207A (zh) 2004-09-20 2007-12-05 泽农医药公司 杂环衍生物及其作为硬脂酰CoA去饱和酶抑制剂的用途
WO2006034279A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as therapeutic agents
DOP2006000010A (es) 2005-01-10 2006-07-31 Arena Pharm Inc Procedimiento para preparar eteres aromáticos
MY148521A (en) 2005-01-10 2013-04-30 Arena Pharm Inc Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
JP5388574B2 (ja) 2005-05-31 2014-01-15 バーテックス ファーマシューティカルズ インコーポレイテッド イオンチャネルのモジュレーターとして有用なヘテロ環式類
AU2006343359A1 (en) 2005-06-03 2007-11-15 Xenon Pharmaceuticals Inc. Aminothiazole derivatives as human stearoyl-coa desaturase inhibitors
JO2660B1 (en) 2006-01-20 2012-06-17 نوفارتيس ايه جي Pi-3 inhibitors and methods of use
ATE551334T1 (de) 2007-02-06 2012-04-15 Novartis Ag Pi3-kinase-hemmer und verfahren zu ihrer verwendung
JP5465177B2 (ja) 2007-09-20 2014-04-09 アイアールエム・リミテッド・ライアビリティ・カンパニー Ｇｐｒ１１９活性のモジュレーターとしての化合物および組成物
CN103539791B (zh) 2010-09-22 2017-01-11 艾尼纳制药公司 Gpr119 受体调节剂和对与其相关的障碍的治疗
PH12014500682A1 (en) 2011-09-27 2014-05-12 Novartis Ag 3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant idh
CN103204816B (zh) 2012-01-16 2016-04-27 中国人民解放军军事医学科学院毒物药物研究所 哌嗪基嘧啶类衍生物及其制备方法和用途
UY34632A (es) 2012-02-24 2013-05-31 Novartis Ag Compuestos de oxazolidin- 2- ona y usos de los mismos
US9296733B2 (en) 2012-11-12 2016-03-29 Novartis Ag Oxazolidin-2-one-pyrimidine derivative and use thereof for the treatment of conditions, diseases and disorders dependent upon PI3 kinases
GEP201706699B (en) 2013-03-14 2017-07-10 Novartis Ag 3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant idh
CA3002540C (en) 2015-01-06 2023-11-07 Arena Pharmaceuticals, Inc. Use of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid for treating conditions related to the s1p1 receptor
WO2016209809A1 (en) 2015-06-22 2016-12-29 Arena Pharmaceuticals, Inc. Crystalline l-arginine salt of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid(compound1) for use in sipi receptor-associated disorders
US11534424B2 (en) 2017-02-16 2022-12-27 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis
ES2987794T3 (es) 2018-06-06 2024-11-18 Arena Pharm Inc Procedimientos de tratamiento de afecciones relacionadas con el receptor S1P1

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57122082A (en) * 1980-12-11 1982-07-29 Bristol Myers Co Buspirone manufacture
JP2006514118A (ja) * 2002-11-21 2006-04-27 カイロン コーポレイション ホスホチジルイノシトール（ｐｉ）３−キナーゼインヒビターとしての２，４，６−三置換ピリミジン、および癌の処置におけるその使用
JP2006516572A (ja) * 2003-01-14 2006-07-06 アリーナ ファーマシューティカルズ， インコーポレイテッド 代謝モジュレーターとしての１，２，３−トリ置換アリール誘導体および１，２，３−トリ置換ヘテロアリール誘導体ならびにこれらの誘導体に関連する糖尿病および高血糖のような障害の予防および処置
JP2011051998A (ja) * 2003-01-14 2011-03-17 Arena Pharmaceuticals Inc 代謝モジュレーターとしての１，２，３−トリ置換アリール誘導体および１，２，３−トリ置換ヘテロアリール誘導体ならびにこれらの誘導体に関連する糖尿病および高血糖のような障害の予防および処置
JP2007522197A (ja) * 2004-02-10 2007-08-09 サノフイ−アベンテイス オレキシン受容体アンタゴニストとしてのピリミジン誘導体
WO2005085212A1 (ja) * 2004-03-04 2005-09-15 Astellas Pharma Inc. 置換ピリミジン誘導体
JP2008546731A (ja) * 2005-06-23 2008-12-25 ノバルティス アクチエンゲゼルシャフト Ｇａｂａｂ仲介神経系障害の処置のためのピリミジン誘導体
WO2009123221A1 (ja) * 2008-03-31 2009-10-08 全薬工業株式会社 細胞保護作用を有するピリミジン誘導体およびその用途
US8563715B2 (en) 2008-03-31 2013-10-22 Zenyaku Kogyo Kabushikikaisha Pyrimidine derivative having cell protecting effect and uses thereof
JP5369093B2 (ja) * 2008-03-31 2013-12-18 全薬工業株式会社 細胞保護作用を有するピリミジン誘導体およびその用途
JP2014208692A (ja) * 2008-12-09 2014-11-06 ギリアード サイエンシーズ， インコーポレイテッド Ｔｏｌｌ様受容体のモジュレーター

Also Published As

Publication number Publication date
DE2341925A1 (de) 1975-03-06
BE818990A (fr) 1975-02-19
ZA745305B (en) 1976-04-28

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