JPS5018480A - - Google Patents
Info
- Publication number
- JPS5018480A JPS5018480A JP49053155A JP5315574A JPS5018480A JP S5018480 A JPS5018480 A JP S5018480A JP 49053155 A JP49053155 A JP 49053155A JP 5315574 A JP5315574 A JP 5315574A JP S5018480 A JPS5018480 A JP S5018480A
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
- C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH672273A CH578534A5 (en) | 1973-05-11 | 1973-05-11 | Quinoline-3-carboxylic acid derivs - with e.g. analgesic, antinociceptive, antiinflammatory and antiallergic props |
| CH393574 | 1974-03-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5018480A true JPS5018480A (ja) | 1975-02-26 |
Family
ID=25694221
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP49053155A Pending JPS5018480A (ja) | 1973-05-11 | 1974-05-11 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3960868A (ja) |
| JP (1) | JPS5018480A (ja) |
| AT (1) | AT332406B (ja) |
| AU (1) | AU6877174A (ja) |
| CA (1) | CA1034124A (ja) |
| DE (1) | DE2421121A1 (ja) |
| FR (1) | FR2228488B1 (ja) |
| GB (1) | GB1467061A (ja) |
| NL (1) | NL7405910A (ja) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54132582A (en) * | 1978-02-24 | 1979-10-15 | Bayer Ag | Manufacture of 44pyridonee33carboxylic acid and*or its derivative |
| JPS5731665A (en) * | 1980-05-19 | 1982-02-20 | Roussel Uclaf | 2-position substituted 4-hydroxy-3-quinoline carboxylic acid novel derivative, manufacture, use as drug and composition and novel intermediate containing same |
| JPS582273A (ja) * | 1981-06-16 | 1983-01-07 | アドヴァンスト コンポジット マティリアルズ コーポレーション | 炭化ケイ素ホイスカ−複合物における改良 |
| JPS58105965A (ja) * | 1981-12-15 | 1983-06-24 | Nippon Shinyaku Co Ltd | 置換キノリンカルボン酸誘導体 |
| WO1990013542A1 (fr) * | 1989-04-28 | 1990-11-15 | Daiichi Pharmaceutical Co., Ltd. | Medicament anti-hiv |
| JP2009544732A (ja) * | 2006-07-26 | 2009-12-17 | ノバルティス アクチエンゲゼルシャフト | ウンデカプレニルピロホスフェートシンターゼの阻害剤 |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4190659A (en) | 1973-08-27 | 1980-02-26 | Sandoz, Inc. | Pharmaceutical preparation and use of 4-hydroxy-2-quinolinone-3-carboxylic acid esters |
| US4187309A (en) * | 1977-06-20 | 1980-02-05 | Sandoz, Inc. | 4-Hydroxy-2-quinolinone-3-carboxylic acids and salts thereof |
| US4273930A (en) * | 1977-06-20 | 1981-06-16 | Sandoz, Inc. | 4-Hydroxy-2-quinolinone-3-carboxylic acid esters |
| US4281131A (en) * | 1977-06-20 | 1981-07-28 | Sandoz, Inc. | 4-Hydroxy-2-quinolinone-3-carboxylic acids and salts thereof |
| US4128649A (en) * | 1977-06-29 | 1978-12-05 | Sandoz, Inc. | 4-Hydroxy-pyrido[2,3-b]pyridine-2(1H)-one-3-carboxylic acids and esters |
| US4119720A (en) * | 1977-07-06 | 1978-10-10 | Sandoz, Inc. | Unsaturated esters of 4-hydroxy-2-quinolinone-3-carboxylic acids and salts thereof |
| US4169893A (en) * | 1978-03-13 | 1979-10-02 | Sandoz, Inc. | 4-hydroxy-naphthpyridine-2(1h)-one-3-carboxylic acids and esters |
| IE52670B1 (en) * | 1981-03-03 | 1988-01-20 | Leo Ab | Heterocyclic carboxamides,compositions containing such compounds,and processes for their preparation |
| FR2509728A1 (fr) * | 1981-07-17 | 1983-01-21 | Roussel Uclaf | Nouveaux derives de la quinoleine, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
| JPS58219166A (ja) * | 1982-06-14 | 1983-12-20 | Nippon Shinyaku Co Ltd | ４−キノロン誘導体 |
| DE3430800A1 (de) * | 1984-08-22 | 1986-03-06 | Bayer Ag, 5090 Leverkusen | Anzinpigmente |
| EP0184384B1 (en) * | 1984-12-06 | 1989-08-02 | Pfizer Inc. | Substituted dihydroquinolone carboxylic acids, anti-bacterial compositions containing them |
| US4929613A (en) * | 1987-08-26 | 1990-05-29 | Warner-Lambert Company | Antibacterial agents |
| DE3811341A1 (de) * | 1987-10-09 | 1989-04-27 | Bayer Ag | In 7-stellung c-verknuepfte chinolon- und 1,8-naphthyridin-4-on-carbonsaeure und ein verfahren zu ihrer herstellung |
| US5103040A (en) * | 1988-06-21 | 1992-04-07 | Pfizer Inc. | 6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acid derivatives and intermediates therefor |
| US5104868A (en) * | 1988-06-21 | 1992-04-14 | Pfizer Inc. | Tricyclic derivatives of 7-substituted-6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acids and esters |
| US5039682A (en) * | 1988-06-21 | 1991-08-13 | Pfizer Inc. | 6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acid derivatives and intermediates therefor |
| US5233091A (en) * | 1988-06-21 | 1993-08-03 | Pfizer Inc. | 6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acid derivatives and intermediates therefor |
| US5310913A (en) * | 1989-06-09 | 1994-05-10 | Kabi Pharmacia Aktiebolag | Derivatives of quinoline-3-carboxanilide |
| US4992449A (en) * | 1990-02-01 | 1991-02-12 | American Cyanamid Company | 7-(substituted)cycloalkylamino-1-(substituted)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids |
| JPH07110853B2 (ja) * | 1990-09-07 | 1995-11-29 | シェリング・コーポレーション | 抗ウイルス化合物および抗高血圧化合物 |
| AU8448491A (en) * | 1990-09-07 | 1992-03-30 | Schering Corporation | Antiviral compounds and antihypertensive compounds |
| US5179093A (en) * | 1991-05-10 | 1993-01-12 | Schering Corporation | Quinoline-diones |
| DE4138820A1 (de) * | 1991-11-26 | 1993-05-27 | Basf Ag | Chinolin-3-carbonsaeureamide, deren herstellung und verwendung |
| SE9201076L (sv) * | 1992-04-06 | 1993-10-07 | Shimon Slavin | Användningen av gamla läkemedel för behandling av diabetes |
| SE9400809D0 (sv) * | 1994-03-10 | 1994-03-10 | Pharmacia Ab | New use of quinoline-3-carboxamide compounds |
| SE9400810D0 (sv) * | 1994-03-10 | 1994-03-10 | Pharmacia Ab | New use of Quinoline-3-carboxamide compounds |
| CA2309882A1 (en) * | 1997-12-22 | 1999-07-01 | Pharmacia & Upjohn Company | 4-hydroxyquinoline-3-carboxamides and hydrazides as antiviral agents |
| US6248739B1 (en) * | 1999-01-08 | 2001-06-19 | Pharmacia & Upjohn Company | Quinolinecarboxamides as antiviral agents |
| CA2813711A1 (en) | 2010-10-14 | 2012-04-19 | Immunahr Ab | 1,2-dihydro-4-hydroxy-2-oxo-quinoline-3-carboxanilides as ahr activators. |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB830832A (en) * | 1957-02-15 | 1960-03-23 | Ici Ltd | New quinolones and therapeutic compositions containing them |
| US3452026A (en) * | 1966-03-15 | 1969-06-24 | Bristol Myers Co | Substituted 1,2,3,4-tetrahydroquinolines |
| US3542851A (en) * | 1966-07-01 | 1970-11-24 | Merck & Co Inc | Novel acrylate,amines and ethers |
| US3761592A (en) * | 1969-03-18 | 1973-09-25 | R Mizzoni | Quinoline derivatives exhibiting growth promoting and anticoccidial effects |
| US3506667A (en) * | 1969-05-01 | 1970-04-14 | Warner Lambert Pharmaceutical | Furo quinoline carboxylates |
| BE759357A (fr) * | 1969-11-24 | 1971-04-30 | Sumitomo Chemical Co | Derives de 4-thioxoquinoleine |
| DE2103805C3 (de) * | 1970-01-28 | 1980-03-20 | Sumitomo Chemical Co., Ltd., Osaka (Japan) | Verfahren zur Herstellung von N-substituierten 6,7-Methylendioxy-4chinolonen |
-
1974
- 1974-05-01 CA CA198,654A patent/CA1034124A/en not_active Expired
- 1974-05-02 DE DE2421121A patent/DE2421121A1/de active Pending
- 1974-05-02 NL NL7405910A patent/NL7405910A/xx not_active Application Discontinuation
- 1974-05-06 US US05/467,166 patent/US3960868A/en not_active Expired - Lifetime
- 1974-05-07 GB GB2003774A patent/GB1467061A/en not_active Expired
- 1974-05-07 FR FR7415703A patent/FR2228488B1/fr not_active Expired
- 1974-05-09 AU AU68771/74A patent/AU6877174A/en not_active Expired
- 1974-05-10 AT AT387574A patent/AT332406B/de not_active IP Right Cessation
- 1974-05-11 JP JP49053155A patent/JPS5018480A/ja active Pending
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0433790B2 (ja) * | 1978-02-24 | 1992-06-04 | Bayer Ag | |
| JPS54132582A (en) * | 1978-02-24 | 1979-10-15 | Bayer Ag | Manufacture of 44pyridonee33carboxylic acid and*or its derivative |
| JPH01246265A (ja) * | 1978-02-24 | 1989-10-02 | Bayer Ag | ４‐ピリドン‐３‐カルボン酸誘導体 |
| JPH02117664A (ja) * | 1978-02-24 | 1990-05-02 | Bayer Ag | ４‐ピリドン‐３‐カルボン酸およびその誘導体 |
| JPH0260666B2 (ja) * | 1978-02-24 | 1990-12-17 | Bayer Ag | |
| JPH0433789B2 (ja) * | 1978-02-24 | 1992-06-04 | Bayer Ag | |
| JPS5731665A (en) * | 1980-05-19 | 1982-02-20 | Roussel Uclaf | 2-position substituted 4-hydroxy-3-quinoline carboxylic acid novel derivative, manufacture, use as drug and composition and novel intermediate containing same |
| JPS6340430B2 (ja) * | 1980-05-19 | 1988-08-11 | Roussel Uclaf | |
| JPS582273A (ja) * | 1981-06-16 | 1983-01-07 | アドヴァンスト コンポジット マティリアルズ コーポレーション | 炭化ケイ素ホイスカ−複合物における改良 |
| JPH0530890B2 (ja) * | 1981-06-16 | 1993-05-11 | Adobansuto Konhojitsuto Mateiriaruzu Corp | |
| JPS58105965A (ja) * | 1981-12-15 | 1983-06-24 | Nippon Shinyaku Co Ltd | 置換キノリンカルボン酸誘導体 |
| JPH0312061B2 (ja) * | 1981-12-15 | 1991-02-19 | Nippon Shinyaku Co Ltd | |
| WO1990013542A1 (fr) * | 1989-04-28 | 1990-11-15 | Daiichi Pharmaceutical Co., Ltd. | Medicament anti-hiv |
| JP2009544732A (ja) * | 2006-07-26 | 2009-12-17 | ノバルティス アクチエンゲゼルシャフト | ウンデカプレニルピロホスフェートシンターゼの阻害剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU6877174A (en) | 1975-11-13 |
| NL7405910A (ja) | 1974-11-13 |
| FR2228488B1 (ja) | 1977-05-06 |
| FR2228488A1 (ja) | 1974-12-06 |
| US3960868A (en) | 1976-06-01 |
| DE2421121A1 (de) | 1975-01-16 |
| ATA387574A (de) | 1976-01-15 |
| GB1467061A (en) | 1977-03-16 |
| AT332406B (de) | 1976-09-27 |
| CA1034124A (en) | 1978-07-04 |