JPS5010373B1 - - Google Patents

Info

Publication number
JPS5010373B1
JPS5010373B1 JP42034292A JP3429267A JPS5010373B1 JP S5010373 B1 JPS5010373 B1 JP S5010373B1 JP 42034292 A JP42034292 A JP 42034292A JP 3429267 A JP3429267 A JP 3429267A JP S5010373 B1 JPS5010373 B1 JP S5010373B1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP42034292A
Other languages
Japanese (ja)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS5010373B1 publication Critical patent/JPS5010373B1/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • A61K31/787Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A61K31/79Polymers of vinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP42034292A 1966-05-31 1967-05-31 Pending JPS5010373B1 (enExample)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL6607516A NL6607516A (enExample) 1966-05-31 1966-05-31

Publications (1)

Publication Number Publication Date
JPS5010373B1 true JPS5010373B1 (enExample) 1975-04-21

Family

ID=19796753

Family Applications (1)

Application Number Title Priority Date Filing Date
JP42034292A Pending JPS5010373B1 (enExample) 1966-05-31 1967-05-31

Country Status (22)

Country Link
US (1) US3557280A (enExample)
JP (1) JPS5010373B1 (enExample)
AT (1) AT272522B (enExample)
BE (1) BE699091A (enExample)
CH (1) CH490087A (enExample)
CS (1) CS151454B2 (enExample)
DE (1) DE1617576C3 (enExample)
DK (1) DK117587B (enExample)
ES (1) ES340956A1 (enExample)
FI (1) FI43622B (enExample)
FR (1) FR5953M (enExample)
GB (1) GB1131007A (enExample)
GR (1) GR33861B (enExample)
IL (1) IL28009A (enExample)
IT (1) IT1140250B (enExample)
LU (1) LU53788A1 (enExample)
MY (1) MY7100015A (enExample)
NL (1) NL6607516A (enExample)
NO (1) NO126298B (enExample)
SE (1) SE354417B (enExample)
SU (1) SU510986A3 (enExample)
YU (1) YU31326B (enExample)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
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JPS5418330B2 (enExample) * 1973-03-16 1979-07-06
US3966905A (en) * 1973-05-29 1976-06-29 Barnes-Hind Pharmaceuticals, Inc. Stabilized catechol amine solutions
US3929989A (en) * 1974-06-14 1975-12-30 Wendt Lab Inc Stable suspension of calcium-magnesium oxytetracycline for intrauterine administration in treatment of bovine metritis
GB1538903A (en) * 1975-04-11 1979-01-24 Nelson Res & Dev Carrier for a topically applied physiologically active agent or cosmetic agent
US4018889A (en) * 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions
DE2602363C2 (de) * 1976-01-22 1984-04-12 Bayer Ag, 5090 Leverkusen Wäßrige, injizierbare Niclofolan- Formulierungen
GB1592053A (en) * 1976-12-16 1981-07-01 Norbrook Lab Ltd Oxytetracycline compositions
US4213963A (en) * 1978-12-14 1980-07-22 Janssen Pharmaceutica N.V. Fluspirilene-containing compositions
US4259331A (en) * 1979-04-16 1981-03-31 Pfizer Inc. Oxytetracycline compositions
US4386083A (en) * 1980-04-10 1983-05-31 Walter Hacke Injectable oxytetracycline compositions
US4399127A (en) * 1980-04-10 1983-08-16 Diamond Shamrock Corporation Injectable oxytetracycline compositions
IE74244B1 (en) * 1985-10-01 1997-07-16 Bimeda Res Dev Ltd A process for preparing an antibiotic composition
US5071643A (en) * 1986-10-17 1991-12-10 R. P. Scherer Corporation Solvent system enhancing the solubility of pharmaceuticals for encapsulation
US6756365B2 (en) * 1991-11-06 2004-06-29 Trustees Of Tufts College Reducing tetracycline resistance in living cells
EP0626171A1 (de) * 1993-05-26 1994-11-30 Winfried Dörnhöfer Injektionslösung für die intravenöse oder intramuskuläre Verabreichung an Tiere
US6383515B2 (en) 1999-05-28 2002-05-07 Sawyer Maryjean Solvent system for enhancing solubility
US6500812B2 (en) 1999-09-14 2002-12-31 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
US8106225B2 (en) * 1999-09-14 2012-01-31 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
US6849615B2 (en) 1999-09-14 2005-02-01 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
EA016099B1 (ru) 1999-09-14 2012-02-28 Трастис Оф Тафтс Коллидж Замещенный аналог тетрациклина (варианты) и способ получения замещенного аналога тетрациклина
CA2397863A1 (en) * 2000-01-24 2001-07-26 Trustees Of Tufts College Tetracycline compounds for treatment of cryptosporidium parvum related disorders
CN1430600A (zh) 2000-03-31 2003-07-16 塔夫茨大学信托人 7-和9-氨基甲酸酯、脲、硫脲、硫代氨基甲酸酯,和杂芳基-氨基取代的四环素化合物
JP2003533504A (ja) 2000-05-15 2003-11-11 パラテック ファーマシューティカルズ インコーポレイテッド 7置換型縮合環テトラサイクリン化合物
WO2001098236A2 (en) * 2000-06-16 2001-12-27 Trustees Of Tufts College 7-phenyl-substituted tetracycline compounds
US20040224927A1 (en) 2000-06-16 2004-11-11 Trustees Of Tufts College 7-N-substituted phenyl tetracycline compounds
US20020132798A1 (en) * 2000-06-16 2002-09-19 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
IL153674A0 (en) 2000-07-07 2003-07-06 Tufts College 13-substituted methacycline compounds
EP2289871A1 (en) * 2000-07-07 2011-03-02 Paratek Pharmaceuticals, Inc. 7-substituted tetracycline compounds
US20050143353A1 (en) * 2000-07-07 2005-06-30 Paratek Pharmaceuticals, Inc. 13-Substituted methacycline compounds
US7094806B2 (en) * 2000-07-07 2006-08-22 Trustees Of Tufts College 7, 8 and 9-substituted tetracycline compounds
BRPI0112269B8 (pt) 2000-07-07 2021-05-25 Paratek Pharm Innc composto de minociclina 9-aminometila substituída, e, composição farmacêutica
JP4963771B2 (ja) 2000-07-07 2012-06-27 トラスティーズ・オブ・タフツ・カレッジ 7、8および9−置換テトラサイクリン化合物
EP2301914A1 (en) 2001-03-13 2011-03-30 Paratek Pharmaceuticals, Inc. 7,9-Substituted tetracycline compounds
WO2002072506A2 (en) * 2001-03-13 2002-09-19 Paratek Pharmaceuticals, Inc. 7-pyrollyl tetracycline compounds and methods of use thereof
CA2440757A1 (en) 2001-03-14 2002-09-19 Michael Draper Substituted tetracycline compounds as synergistic antifungal agents
EP1379255A2 (en) 2001-03-14 2004-01-14 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds as antifungal agents
US8088820B2 (en) * 2001-04-24 2012-01-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
WO2002085303A2 (en) 2001-04-24 2002-10-31 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
EP1474380A4 (en) * 2002-01-08 2007-04-18 Paratek Pharm Innc 4-DESDIMETHYL AMINO TETRA CYCLINE COMPOUNDS
CN101307017A (zh) 2002-03-08 2008-11-19 帕拉特克药品公司 氨基-甲基取代的四环素类化合物
CA2479877C (en) 2002-03-21 2012-08-21 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
EP1534300A4 (en) 2002-07-12 2008-04-23 Paratek Pharm Innc TETRACYCLINE COMPOUNDS SUBSTITUTED IN 3, 10, AND 12A
JP2006503898A (ja) 2002-10-24 2006-02-02 パラテック ファーマシューティカルズ, インク. マラリア治療のための置換テトラサイクリン化合物
JP2006514119A (ja) * 2003-02-12 2006-04-27 アール アンド ピー コリア カンパニー リミテッド 溶解率が向上した難溶性薬剤の溶媒系
AU2004259659B2 (en) 2003-07-09 2011-11-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
AU2004259661B2 (en) 2003-07-09 2011-11-10 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
US20060287283A1 (en) * 2003-07-09 2006-12-21 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
US7786099B2 (en) * 2004-01-15 2010-08-31 Paratek Pharmaceuticals, Inc. Aromatic a-ring derivatives of tetracycline compounds
TWI261038B (en) * 2004-08-11 2006-09-01 Bo-Cheng Chen Bicycle gear-shifting handgrip
EP2949644A3 (en) 2004-10-25 2016-04-20 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
US7858601B2 (en) * 2004-10-25 2010-12-28 Paratek Pharmaceuticals, Inc. 4-substituted tetracyclines and methods of use thereof
CA2597212A1 (en) * 2005-02-04 2006-08-10 Paratek Pharmaceuticals, Inc. 11a, 12-derivatives of tetracycline compounds
DE102005012595A1 (de) * 2005-03-18 2006-09-21 Lanxess Deutschland Gmbh Herstellung von Tri(chlorpropyl)phosphat
CA2616224A1 (en) * 2005-07-21 2007-02-01 Paratek Pharmaceuticals, Inc. 10-substituted tetracyclines and methods of use thereof
BRPI0617258A2 (pt) * 2005-09-19 2011-07-19 Albemarle Corparation soluções aquosas escoáveis altamente concentradas de ibuprofeno de potássio suas preparações e seus usos
WO2007087416A2 (en) * 2006-01-24 2007-08-02 Paratek Pharaceuticals, Inc. Methods of increasing oral bioavailability of tetracyclines
EP2007713A2 (en) * 2006-04-17 2008-12-31 Teva Pharmaceutical Industries Ltd Isolation of tetracycline derivatives
CN101479235B (zh) * 2006-04-24 2013-09-18 特瓦制药工业有限公司 替加环素晶形及其制备方法
US8198470B2 (en) * 2006-04-24 2012-06-12 Teva Pharmaceutical Industries Ltd. Crystalline form II of tigecycline and processes for preparation thereof
EP2026776A2 (en) * 2006-05-15 2009-02-25 Paratek Pharmaceuticals, Inc. Methods of regulating expression of genes or of gene products using substituted tetracycline compounds
US8440646B1 (en) 2006-10-11 2013-05-14 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of Bacillus anthracis infections
EP2450347B1 (en) 2006-12-21 2015-06-24 Paratek Pharmaceuticals, Inc. Tetracycline derivatives for the treatment of bacterial, viral and parasitic infections
AU2007338681B2 (en) 2006-12-21 2013-09-26 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of inflammatory skin disorders
CA2688725A1 (en) 2007-04-12 2008-10-23 Paratek Pharmaceuticals, Inc. Methods for treating spinal muscular atrophy using tetracycline compounds
CA2688662A1 (en) 2007-04-27 2008-11-06 Paratek Pharmaceuticals, Inc. Methods for synthesizing and purifying aminoalkyl tetracycline compounds
EP2192111A3 (en) 2007-07-06 2010-10-06 Paratek Pharmaceuticals, Inc. Methods for synthesizing substituted tetracycline compounds
RU2010140682A (ru) 2008-03-05 2012-04-10 Пэрэтек Фамэсьютикэлс, Инк. (US) Способ лечения пациента от инфекции, фармацевтическая композиция (варианты) и лекарственное средство
PT2271348T (pt) 2008-03-28 2018-04-16 Paratek Pharm Innc Formulação de comprimido oral de composto de tetraciclina
WO2009128913A1 (en) * 2008-04-14 2009-10-22 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
TW202332671A (zh) 2008-05-19 2023-08-16 美商Prtk Spv2公司 四環素化合物之甲苯磺酸鹽及同素異形體
US9629809B2 (en) 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
BRPI0916344A2 (pt) 2008-07-21 2020-07-21 Albemarle Corporation grânulos com alto teor de ibuprofeno de sódio, preparação e utilização para preparação de formas de dosagem sólidas não efervescentes
EP2341771A4 (en) * 2008-09-19 2012-08-15 Paratek Pharm Innc TETRACYCLINE COMPOUNDS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS AND RELATED THERAPEUTIC METHODS
JP2012523438A (ja) 2009-04-10 2012-10-04 タフツ メディカル センター インコーポレイテッド メタロプロテイナーゼ−1(mmp−1)によるpar−1活性化
US9255068B2 (en) 2011-05-12 2016-02-09 Warner Chilcott Company, Llc Crystalline salts of (4S,4AS,5AR,12AS)-4-dimethylamino-3,10,12,12A-tetrahydroxy-7-[methoxy(methyl)amino)-methyl] acid amide and methods of using the same
BR112019008897A2 (pt) 2016-11-01 2019-08-13 Paratek Pharm Innc método para tratar pneumonia bacteriana adquirida na comunidade.
ES2962380T3 (es) 2017-07-21 2024-03-18 Almirall Llc Sareciclina para el tratamiento de lesiones de acné no inflamatorias

Also Published As

Publication number Publication date
BE699091A (enExample) 1967-11-27
GB1131007A (en) 1968-10-16
DE1617576B2 (de) 1980-04-10
CH490087A (de) 1970-05-15
MY7100015A (en) 1971-12-31
SU510986A3 (ru) 1976-04-15
NL6607516A (enExample) 1967-12-01
IL28009A (en) 1970-08-19
DE1617576C3 (de) 1980-12-11
GR33861B (el) 1968-02-09
LU53788A1 (enExample) 1967-07-31
YU31326B (en) 1973-04-30
IT1140250B (it) 1986-09-24
CS151454B2 (enExample) 1973-10-19
DE1617576A1 (de) 1972-04-27
NO126298B (enExample) 1973-01-22
US3557280A (en) 1971-01-19
DK117587B (da) 1970-05-11
SE354417B (enExample) 1973-03-12
AT272522B (de) 1969-07-10
ES340956A1 (es) 1968-06-16
FI43622B (enExample) 1971-02-01
FR5953M (enExample) 1968-04-16

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