JPS4954390A - - Google Patents

Info

Publication number
JPS4954390A
JPS4954390A JP48069691A JP6969173A JPS4954390A JP S4954390 A JPS4954390 A JP S4954390A JP 48069691 A JP48069691 A JP 48069691A JP 6969173 A JP6969173 A JP 6969173A JP S4954390 A JPS4954390 A JP S4954390A
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP48069691A
Other versions
JPS5614673B2 (ja
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS4954390A publication Critical patent/JPS4954390A/ja
Publication of JPS5614673B2 publication Critical patent/JPS5614673B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/09—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems
    • C07D489/10—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14
    • C07D489/12—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14 the bridge containing only two carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
JP6969173A 1972-06-21 1973-06-20 Expired JPS5614673B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2230154A DE2230154A1 (de) 1972-06-21 1972-06-21 N-(heteroaryl-methyl)-6,14-endoaetheno7alpha-hydroxyalkyl-tetrahydro-nororipavine und -thebaine, deren hydrierungsprodukte und saeureadditionssalze sowie verfahren zu deren herstellung

Publications (2)

Publication Number Publication Date
JPS4954390A true JPS4954390A (ja) 1974-05-27
JPS5614673B2 JPS5614673B2 (ja) 1981-04-06

Family

ID=5848276

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6969173A Expired JPS5614673B2 (ja) 1972-06-21 1973-06-20

Country Status (14)

Country Link
US (1) US3931189A (ja)
JP (1) JPS5614673B2 (ja)
AT (7) AT328101B (ja)
BE (1) BE801271A (ja)
CH (7) CH585753A5 (ja)
DE (1) DE2230154A1 (ja)
DK (1) DK141629C (ja)
ES (3) ES416106A1 (ja)
FI (1) FI57261C (ja)
FR (1) FR2189066B1 (ja)
GB (1) GB1431385A (ja)
NL (1) NL7308555A (ja)
NO (1) NO139050C (ja)
SE (1) SE412235B (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005506985A (ja) * 2001-09-14 2005-03-10 インスティチュート オブ ファーマコロジー アンド トクシコロジー アカデミー オブ ミリタリー メディカル サイエンス、 ピー．エル．エー．チャイナ 新規オリパビン誘導体および医薬としてのその使用
WO2019189749A1 (ja) * 2018-03-30 2019-10-03 日本ケミファ株式会社 モルヒナン誘導体の製造方法

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4232026A (en) * 1978-07-20 1980-11-04 Merck & Co., Inc. Diazaditwistanes, and pharmaceutical compositions for treating pain in warm blooded animals containing them
JPS60119848A (ja) * 1983-11-30 1985-06-27 三井建設株式会社 繊維補強コンクリ−ト並びにその施工法
JPS62298530A (ja) * 1986-06-16 1987-12-25 Otsuka Pharmaceut Co Ltd 坐薬用医薬組成物
CN1939920B (zh) * 2005-09-29 2011-08-31 中国人民解放军军事医学科学院毒物药物研究所 东罂粟碱类化合物及其医药用途
KR101343395B1 (ko) 2008-07-30 2013-12-19 퍼듀 퍼머 엘피 부프레노르핀 유사체

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3474101A (en) * 1960-09-05 1969-10-21 Reckitt & Sons Ltd Thebaine and oripavine derivatives
US3285914A (en) * 1964-06-11 1966-11-15 Smith Kline French Lab 3-n-substituted derivatives of oripavine and thebaine
GB1136764A (en) * 1965-08-13 1968-12-18 Reckitt & Sons Ltd Derivatives of thebaine and oripavine
GB1146272A (en) * 1966-01-17 1969-03-26 Reckitt & Sons Ltd Novel thebaine and oripavine derivatives
GB1223445A (en) * 1968-07-18 1971-02-24 Reckitt & Colmann Prod Ltd Improvements in or relating to derivatives of morphine, their salts, and processes for their preparation
DE2107989A1 (de) * 1971-02-19 1972-09-07 Boehringer Sohn Ingelheim N-(Furyl-methy])-morphinane, deren Säureadditionssalze sowie Verfahren zu deren Herstellung

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005506985A (ja) * 2001-09-14 2005-03-10 インスティチュート オブ ファーマコロジー アンド トクシコロジー アカデミー オブ ミリタリー メディカル サイエンス、 ピー．エル．エー．チャイナ 新規オリパビン誘導体および医薬としてのその使用
WO2019189749A1 (ja) * 2018-03-30 2019-10-03 日本ケミファ株式会社 モルヒナン誘導体の製造方法

Also Published As

Publication number Publication date
FI57261B (fi) 1980-03-31
ES425015A1 (es) 1976-07-01
AT327409B (de) 1976-01-26
ATA461874A (de) 1975-05-15
FR2189066B1 (ja) 1976-12-31
JPS5614673B2 (ja) 1981-04-06
AT325219B (de) 1975-10-10
BE801271A (fr) 1973-12-21
DE2230154A1 (de) 1974-01-17
ATA462174A (de) 1975-05-15
ATA461974A (de) 1975-05-15
CH585753A5 (ja) 1977-03-15
NO139050B (no) 1978-09-18
ATA462374A (de) 1975-07-15
CH586224A5 (ja) 1977-03-31
FR2189066A1 (ja) 1974-01-25
ATA462274A (de) 1975-04-15
CH594672A5 (ja) 1978-01-13
AT329198B (de) 1976-04-26
DK141629C (da) 1980-09-29
US3931189A (en) 1976-01-06
FI57261C (fi) 1980-07-10
AU5721173A (en) 1975-01-09
GB1431385A (en) 1976-04-07
CH585751A5 (ja) 1977-03-15
ES416106A1 (es) 1976-02-16
ATA462074A (de) 1975-05-15
CH587264A5 (ja) 1977-04-29
NL7308555A (ja) 1973-12-27
AT328099B (de) 1976-03-10
AT328098B (de) 1976-03-10
DK141629B (da) 1980-05-12
NO139050C (no) 1979-01-03
CH594673A5 (ja) 1978-01-13
AT328100B (de) 1976-03-10
CH585752A5 (ja) 1977-03-15
SE412235B (sv) 1980-02-25
AT328101B (de) 1976-03-10
ES425010A1 (es) 1976-06-16

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