JPS4864097A - - Google Patents
Info
- Publication number
- JPS4864097A JPS4864097A JP47123877A JP12387772A JPS4864097A JP S4864097 A JPS4864097 A JP S4864097A JP 47123877 A JP47123877 A JP 47123877A JP 12387772 A JP12387772 A JP 12387772A JP S4864097 A JPS4864097 A JP S4864097A
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20653871A | 1971-12-09 | 1971-12-09 | |
| US245870A US3925385A (en) | 1972-04-20 | 1972-04-20 | 6-Carbethoxy-3,7-disubstitutedpyrazolo{8 1,5a{9 pyrimidines |
| US27346572A | 1972-07-20 | 1972-07-20 | |
| US29984072A | 1972-10-24 | 1972-10-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS4864097A true JPS4864097A (instruction) | 1973-09-05 |
Family
ID=27498614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP47123877A Pending JPS4864097A (instruction) | 1971-12-09 | 1972-12-09 |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS4864097A (instruction) |
| BE (1) | BE792533A (instruction) |
| BG (1) | BG22401A3 (instruction) |
| CH (1) | CH603652A5 (instruction) |
| DD (1) | DD104530A5 (instruction) |
| DE (1) | DE2257547A1 (instruction) |
| GB (1) | GB1412017A (instruction) |
| HU (1) | HU168530B (instruction) |
| IE (1) | IE37189B1 (instruction) |
| IL (1) | IL40895A (instruction) |
| LU (1) | LU66597A1 (instruction) |
| NL (1) | NL7216539A (instruction) |
| NO (1) | NO137012C (instruction) |
| RO (1) | RO62762A (instruction) |
| SE (1) | SE398751B (instruction) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992018504A1 (fr) * | 1991-04-22 | 1992-10-29 | Otsuka Pharmaceutical Factory, Inc. | DERIVE DE PYRAZOLO[1,5-a]PYRIMIDINE ET AGENT ANTI-INFLAMMATOIRECONTENANT CE DERIVE |
| WO1995035298A1 (fr) * | 1994-06-21 | 1995-12-28 | Otsuka Pharmaceutical Factory, Inc. | DERIVE DE PYRAZOLO[1,5-a]PYRIMIDINE |
| JP2007522220A (ja) * | 2004-02-11 | 2007-08-09 | シェーリング コーポレイション | サイクリン依存性キナーゼインヒビターとしてのピラゾロピリミジン誘導体 |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4281000A (en) * | 1979-07-09 | 1981-07-28 | American Cyanamid Company | Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents |
| AU557300B2 (en) * | 1982-03-16 | 1986-12-18 | Farmitalia Carlo Erba S.P.A. | Substituted 1h-pyrazolo(1,5-alpha)pyrimidines and processes for their preparation |
| ZA831407B (en) * | 1982-03-25 | 1983-11-30 | Erba Farmitalia | Substituted ethenyl derivatives of 1h-pyrazolo(1,5-a)pyrimidine and process for their preparation |
| NZ208554A (en) * | 1983-06-23 | 1987-06-30 | American Cyanamid Co | (aryl and heteroaryl)-(7-(aryl and heteroaryl)-pyrazolo (1,5-a) pyrimidin-3-yl)-methanone derivatives and pharmaceutical compositions |
| DE3533050A1 (de) * | 1985-09-17 | 1987-03-26 | Basf Ag | 7-amino-azolo(1,5-a)pyrimidine, verfahren zu ihrer herstellung und diese enthaltende fungizide, bzw. deren verwendung als fungizide |
| CA1330079C (en) * | 1988-10-13 | 1994-06-07 | Michihiko Tsujitani | Pyrrolo (3,2-e)pyrazolo(1,5-a)pyrimidine derivative and medicine comprising the same |
| DE4333705C2 (de) * | 1993-10-02 | 2003-10-30 | Guenter Ege | Arylmethylsubstituierte Pyrazolo-azine, insbesondere 3-Arylmethylpyrazolo[1,5-a]pyrimidine und Verfahren zur Herstellung von 8-Arylmethyl-pyrazolo[5,1-c][1,2,4]triazinen |
| CN1169149A (zh) * | 1995-09-28 | 1997-12-31 | 株式会社大制药工场 | 止痛组合物 |
| FR2771631B1 (fr) * | 1997-12-03 | 2001-02-02 | Oreal | Compositions de teinture des fibres keratiniques contenant des 3-amino pyrazolo-[1,5-a]-pyrimidines, procede de teinture, nouvelles 3-amino pyrazolo- [1,5-a]-pyrimidines et leur procede de preparation |
| ATE469903T1 (de) * | 2002-09-04 | 2010-06-15 | Schering Corp | Zur behandlung von krebserkrankungen geeignete pyrazolopyrimidine |
| US7161003B1 (en) | 2002-09-04 | 2007-01-09 | Schering Corporation | Pyrazolopyrimidines as cyclin dependent kinase inhibitors |
| ES2222813B1 (es) * | 2003-07-24 | 2005-12-16 | Ferrer Internacional, S.A. | N-(3-(3-sustituidas-pirazolo(1,5-a)pirimidin-7-il)-fenil)-sulfonamidas y composiciones y metodos relacionados. |
| TWI252851B (en) * | 2003-07-24 | 2006-04-11 | Ferrer Int | 7-substituted 3-nitro-pyrazolo[1,5-a]pyrimidines and compositions and methods related thereto |
| KR101793807B1 (ko) | 2013-04-25 | 2017-11-03 | 베이진 엘티디 | 단백질 키나제 억제제로서의 융합된 헤테로시클릭 화합물 |
| BR112016005408B1 (pt) | 2013-09-13 | 2023-03-21 | Beigene Switzerland Gmbh | Anticorpos anti-pd1, f(ab) ou f(ab)2 e uso referido anticorpo para tratamento de cancer ou infecção viral |
| KR102130600B1 (ko) | 2014-07-03 | 2020-07-08 | 베이진 엘티디 | Pd-l1 항체와 이를 이용한 치료 및 진단 |
| US10864203B2 (en) | 2016-07-05 | 2020-12-15 | Beigene, Ltd. | Combination of a PD-1 antagonist and a RAF inhibitor for treating cancer |
| KR20250052473A (ko) | 2016-08-16 | 2025-04-18 | 베이진 스위찰랜드 게엠베하 | (s)-7-(1-아크릴로일피페리딘-4-일)-2-(4-페녹시페닐)-4,5,6,7-테트라-하이드로피라졸로[1,5-a] 피리미딘-3-카르복스아미드의 제조 및 그 용도 |
| HUE065528T2 (hu) | 2016-08-19 | 2024-06-28 | Beigene Switzerland Gmbh | Zanubrutinib kombinációja anti-CD20 vagy anti-PD-1 antitesttel rák kezelésében történõ alkalmazásra |
| EP3573989A4 (en) | 2017-01-25 | 2020-11-18 | Beigene, Ltd. | CRYSTALLINE FORMS OF (S) -7- (1- (BUT-2-YNOYL) PIPERIDIN-4-YL) -2- (4-PHENOXYPHENYL) -4, 5, 6, 7-TETRAHY DROPYRAZOLO [1, 5-A ] PYRIMIDINE-3-CARBOXAMIDE, PREPARATION AND ASSOCIATED USES |
| KR102757960B1 (ko) | 2017-06-26 | 2025-01-22 | 베이진 엘티디 | 간세포암(hepatocellular carcinoma: HCC)에 대한 면역 치료 |
| WO2019034009A1 (en) | 2017-08-12 | 2019-02-21 | Beigene, Ltd. | BTK INHIBITOR WITH ENHANCED DOUBLE SELECTIVITY |
| US11786529B2 (en) | 2017-11-29 | 2023-10-17 | Beigene Switzerland Gmbh | Treatment of indolent or aggressive B-cell lymphomas using a combination comprising BTK inhibitors |
| WO2020249001A1 (zh) | 2019-06-10 | 2020-12-17 | 百济神州瑞士有限责任公司 | 一种含有布鲁顿氏酪氨酸激酶抑制剂的口服固体片剂及其制备方法 |
| US11786531B1 (en) | 2022-06-08 | 2023-10-17 | Beigene Switzerland Gmbh | Methods of treating B-cell proliferative disorder |
-
0
- BE BE792533D patent/BE792533A/xx unknown
-
1972
- 1972-11-21 IE IE1612/72A patent/IE37189B1/xx unknown
- 1972-11-22 IL IL40895A patent/IL40895A/en unknown
- 1972-11-23 DE DE2257547A patent/DE2257547A1/de active Pending
- 1972-12-01 GB GB5558772A patent/GB1412017A/en not_active Expired
- 1972-12-05 SE SE7215829A patent/SE398751B/xx unknown
- 1972-12-05 LU LU66597A patent/LU66597A1/xx unknown
- 1972-12-06 CH CH1775172A patent/CH603652A5/xx not_active IP Right Cessation
- 1972-12-06 NL NL7216539A patent/NL7216539A/xx not_active Application Discontinuation
- 1972-12-06 NO NO4476/72A patent/NO137012C/no unknown
- 1972-12-07 DD DD167370A patent/DD104530A5/xx unknown
- 1972-12-08 HU HUIE548A patent/HU168530B/hu unknown
- 1972-12-09 JP JP47123877A patent/JPS4864097A/ja active Pending
- 1972-12-09 BG BG022071A patent/BG22401A3/xx unknown
- 1972-12-09 RO RO7200073093A patent/RO62762A/ro unknown
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992018504A1 (fr) * | 1991-04-22 | 1992-10-29 | Otsuka Pharmaceutical Factory, Inc. | DERIVE DE PYRAZOLO[1,5-a]PYRIMIDINE ET AGENT ANTI-INFLAMMATOIRECONTENANT CE DERIVE |
| WO1995035298A1 (fr) * | 1994-06-21 | 1995-12-28 | Otsuka Pharmaceutical Factory, Inc. | DERIVE DE PYRAZOLO[1,5-a]PYRIMIDINE |
| JP2007522220A (ja) * | 2004-02-11 | 2007-08-09 | シェーリング コーポレイション | サイクリン依存性キナーゼインヒビターとしてのピラゾロピリミジン誘導体 |
| JP2010215675A (ja) * | 2004-02-11 | 2010-09-30 | Schering Corp | サイクリン依存性キナーゼインヒビターとしてのピラゾロピリミジン誘導体 |
| JP4845743B2 (ja) * | 2004-02-11 | 2011-12-28 | シェーリング コーポレイション | サイクリン依存性キナーゼインヒビターとしてのピラゾロピリミジン誘導体 |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2257547A1 (de) | 1973-06-14 |
| SE398751B (sv) | 1978-01-16 |
| HU168530B (instruction) | 1976-05-28 |
| BG22401A3 (bg) | 1977-02-20 |
| RO62762A (fr) | 1978-05-15 |
| BE792533A (fr) | 1973-06-08 |
| IL40895A0 (en) | 1973-01-30 |
| LU66597A1 (instruction) | 1973-03-15 |
| NO137012C (no) | 1977-12-14 |
| DD104530A5 (instruction) | 1974-03-12 |
| IE37189L (en) | 1973-06-09 |
| NL7216539A (instruction) | 1973-06-13 |
| GB1412017A (en) | 1975-10-29 |
| IE37189B1 (en) | 1977-05-25 |
| NO137012B (no) | 1977-09-05 |
| CH603652A5 (instruction) | 1978-08-31 |
| IL40895A (en) | 1976-12-31 |