SE398751B - Analogiforfarande for framstellning av pyrazolo/1,5-a/pyrimidiner - Google Patents

Analogiforfarande for framstellning av pyrazolo/1,5-a/pyrimidiner

Info

Publication number
SE398751B
SE398751B SE7215829A SE1582972A SE398751B SE 398751 B SE398751 B SE 398751B SE 7215829 A SE7215829 A SE 7215829A SE 1582972 A SE1582972 A SE 1582972A SE 398751 B SE398751 B SE 398751B
Authority
SE
Sweden
Prior art keywords
pyrimidines
preparing pyrazolo
analogical procedure
analogical
procedure
Prior art date
Application number
SE7215829A
Other languages
English (en)
Inventor
R K Robins
D E O'brien
T Novinson
R H Springer
Original Assignee
Icn Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US245870A external-priority patent/US3925385A/en
Application filed by Icn Pharmaceuticals filed Critical Icn Pharmaceuticals
Publication of SE398751B publication Critical patent/SE398751B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7215829A 1971-12-09 1972-12-05 Analogiforfarande for framstellning av pyrazolo/1,5-a/pyrimidiner SE398751B (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US20653871A 1971-12-09 1971-12-09
US245870A US3925385A (en) 1972-04-20 1972-04-20 6-Carbethoxy-3,7-disubstitutedpyrazolo{8 1,5a{9 pyrimidines
US27346572A 1972-07-20 1972-07-20
US29984072A 1972-10-24 1972-10-24

Publications (1)

Publication Number Publication Date
SE398751B true SE398751B (sv) 1978-01-16

Family

ID=27498614

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7215829A SE398751B (sv) 1971-12-09 1972-12-05 Analogiforfarande for framstellning av pyrazolo/1,5-a/pyrimidiner

Country Status (15)

Country Link
JP (1) JPS4864097A (sv)
BE (1) BE792533A (sv)
BG (1) BG22401A3 (sv)
CH (1) CH603652A5 (sv)
DD (1) DD104530A5 (sv)
DE (1) DE2257547A1 (sv)
GB (1) GB1412017A (sv)
HU (1) HU168530B (sv)
IE (1) IE37189B1 (sv)
IL (1) IL40895A (sv)
LU (1) LU66597A1 (sv)
NL (1) NL7216539A (sv)
NO (1) NO137012C (sv)
RO (1) RO62762A (sv)
SE (1) SE398751B (sv)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4281000A (en) * 1979-07-09 1981-07-28 American Cyanamid Company Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents
AU557300B2 (en) * 1982-03-16 1986-12-18 Farmitalia Carlo Erba S.P.A. Substituted 1h-pyrazolo(1,5-alpha)pyrimidines and processes for their preparation
ZA831407B (en) * 1982-03-25 1983-11-30 Erba Farmitalia Substituted ethenyl derivatives of 1h-pyrazolo(1,5-a)pyrimidine and process for their preparation
NZ208554A (en) * 1983-06-23 1987-06-30 American Cyanamid Co (aryl and heteroaryl)-(7-(aryl and heteroaryl)-pyrazolo (1,5-a) pyrimidin-3-yl)-methanone derivatives and pharmaceutical compositions
DE3533050A1 (de) * 1985-09-17 1987-03-26 Basf Ag 7-amino-azolo(1,5-a)pyrimidine, verfahren zu ihrer herstellung und diese enthaltende fungizide, bzw. deren verwendung als fungizide
CA1330079C (en) * 1988-10-13 1994-06-07 Michihiko Tsujitani Pyrrolo (3,2-e)pyrazolo(1,5-a)pyrimidine derivative and medicine comprising the same
DE69130683T2 (de) * 1991-04-22 1999-05-06 Otsuka Pharma Co Ltd PYRAZOLO[1,5-a]PYRIMIDINDERIVATE UND SIE ENTHALTENDE ANTIINFLAMMATORISCHE MITTEL
DE4333705C2 (de) * 1993-10-02 2003-10-30 Guenter Ege Arylmethylsubstituierte Pyrazolo-azine, insbesondere 3-Arylmethylpyrazolo[1,5-a]pyrimidine und Verfahren zur Herstellung von 8-Arylmethyl-pyrazolo[5,1-c][1,2,4]triazinen
KR100315837B1 (ko) * 1994-06-21 2002-02-28 고리 히데아끼 피라졸로[1,5-a]피리미딘유도체
EP0795555A4 (en) * 1995-09-28 1998-01-07 Otsuka Pharma Co Ltd ANALGETICS
FR2771631B1 (fr) * 1997-12-03 2001-02-02 Oreal Compositions de teinture des fibres keratiniques contenant des 3-amino pyrazolo-[1,5-a]-pyrimidines, procede de teinture, nouvelles 3-amino pyrazolo- [1,5-a]-pyrimidines et leur procede de preparation
KR101088922B1 (ko) * 2002-09-04 2011-12-01 파마코페이아, 엘엘씨. 사이클린 의존성 키나제 억제제로서의 피라졸로피리미딘
US7161003B1 (en) 2002-09-04 2007-01-09 Schering Corporation Pyrazolopyrimidines as cyclin dependent kinase inhibitors
US7119200B2 (en) * 2002-09-04 2006-10-10 Schering Corporation Pyrazolopyrimidines as cyclin dependent kinase inhibitors
ES2222813B1 (es) * 2003-07-24 2005-12-16 Ferrer Internacional, S.A. N-(3-(3-sustituidas-pirazolo(1,5-a)pirimidin-7-il)-fenil)-sulfonamidas y composiciones y metodos relacionados.
TWI252851B (en) * 2003-07-24 2006-04-11 Ferrer Int 7-substituted 3-nitro-pyrazolo[1,5-a]pyrimidines and compositions and methods related thereto
DK2989106T3 (en) 2013-04-25 2017-03-20 Beigene Ltd CONDENSED HETEROCYCLIC COMPOUNDS AS PROTEINKINASE INHIBITORS
CN107011441B (zh) 2013-09-13 2020-12-01 百济神州(广州)生物科技有限公司 抗pd1抗体及其作为治疗剂与诊断剂的用途
KR102003754B1 (ko) 2014-07-03 2019-07-25 베이진 엘티디 Pd-l1 항체와 이를 이용한 치료 및 진단
CN109475536B (zh) 2016-07-05 2022-05-27 百济神州有限公司 用于治疗癌症的PD-l拮抗剂和RAF抑制剂的组合
JP7402685B2 (ja) 2016-08-16 2023-12-21 ベイジーン スウィッツァーランド ゲーエムベーハー （ｓ）－７－（１－アクリロイルピペリジン－４－イル）－２－（４－フェノキシフェニル）－４，５，６，７－テトラ－ヒドロピラゾロ［１，５－ａ］ピリミジン－３－カルボキサミドの結晶形、その調製、及びその使用
WO2018033135A1 (en) 2016-08-19 2018-02-22 Beigene, Ltd. Use of a combination comprising a btk inhibitor for treating cancers
EP3573989A4 (en) 2017-01-25 2020-11-18 Beigene, Ltd. CRYSTALLINE FORMS OF (S) -7- (1- (BUT-2-YNOYL) -PIPERIDINE-4-YL) -2- (4-PHENOXYPHENYL) -4,5,6,7-TETRAHYDROPYRAZOLO [1,5-A ] PYRIMIDINE-3-CARBOXAMIDE, MANUFACTURING AND USES THEREOF
EP3645569A4 (en) 2017-06-26 2021-03-24 BeiGene, Ltd. IMMUNOTHERAPY FOR LIVER CELL CARCINOMA
US11377449B2 (en) 2017-08-12 2022-07-05 Beigene, Ltd. BTK inhibitors with improved dual selectivity
WO2019108795A1 (en) 2017-11-29 2019-06-06 Beigene Switzerland Gmbh Treatment of indolent or aggressive b-cell lymphomas using a combination comprising btk inhibitors
US11786531B1 (en) 2022-06-08 2023-10-17 Beigene Switzerland Gmbh Methods of treating B-cell proliferative disorder

Also Published As

Publication number Publication date
NL7216539A (sv) 1973-06-13
RO62762A (fr) 1978-05-15
IL40895A (en) 1976-12-31
IE37189B1 (en) 1977-05-25
DD104530A5 (sv) 1974-03-12
BG22401A3 (sv) 1977-02-20
BE792533A (fr) 1973-06-08
IE37189L (en) 1973-06-09
NO137012C (no) 1977-12-14
DE2257547A1 (de) 1973-06-14
JPS4864097A (sv) 1973-09-05
GB1412017A (en) 1975-10-29
NO137012B (no) 1977-09-05
IL40895A0 (en) 1973-01-30
CH603652A5 (sv) 1978-08-31
LU66597A1 (sv) 1973-03-15
HU168530B (sv) 1976-05-28

Similar Documents

Publication Publication Date Title
SE398751B (sv) Analogiforfarande for framstellning av pyrazolo/1,5-a/pyrimidiner
SE402592B (sv) Forfarande for framstellning av 2-alkyl-3-acyl-pyrazolo(1,5-a)pyridiner
SE402915B (sv) Forfarande for framstellning av imidazo(5,1-f)triazinoner med terapeutisk verkan
AR193536A1 (es) Procedimiento para la preparacion de compuestos de pirazolo(1,5a)pirimidina
SE396388B (sv) Analogiforfrande for framstellning av 2,3-dihydro-oxo-imidazo-/1,2-a/pyrimidiner
FI54121B (fi) Foerfarande foer framstaellning av blodtryckssaenkande imidazo-(1,2-a)-imidazoler -pyrimidiner och diazepiner och deras syraadditionssalter
SE389499B (sv) Analogiforfarande for framstellning av triazolo(4,3-a)(1,4)bensodiazepin-derivat
NO147916C (no) Fremgangsmaate for fremstilling av 3-metylen-cefalosporin-forbindelser.
SE410604B (sv) Analogiforfarande for framstellning av pyrazolo(3,4-e)(1,4)diazepinforeningar
SE402012B (sv) Analogiforfarande for framstellning av s-triazolo(1,5-a)(1,4)diazepinderivat
FI54123B (fi) Foerfarande foer framstaellning av 2,3,9,13b-tetrahydro-1h-dibenso(c,f)-imidazo(3,4-a)azepiner med antiseroton- och antihistaminverkan
AR192347A1 (es) Procedimiento para la preparacion de 3-amino-imidazo(1,5-a)piridinas
SE398343B (sv) Forfarande for framstellning av porosa formkroppar
SE380804B (sv) Anologiforfarande for framstellning av s-triazolo (1,5-a) (1,4)
FI55845C (fi) Foerfarande foer framstaellning av en 8-d-ribityl-pyrido(2,3-d)pyrimidin
SE386175B (sv) Forfarande for framstellning av 1,4-bis-acylpiperaziner
SE398501B (sv) Analogiforfarande for framstellning av 1,4-bensodiazepinderivat
NO136574C (no) Analogifremgangsm}te for fremstilling av terapeutisk aktive pyrimidinderivater.
SE398122B (sv) Analogiforfarande for framstellning av pyrazino/1,2-a/indol-2-karboxamidiner
SE399709B (sv) Sett att framstella pyrimido(1,2-a)(1,4)bensodiazepiner
SE405119B (sv) Forfarande for framstellning av 2,4-diamino-5-bensyl-pyrimidiner
SE390025B (sv) Forfarande for framstellning av 3 alfa-hydroxi-19-5 alfa-pregnan-11,20-dion
SE419087B (sv) Analogiforfarande for framstellning av imidazo/1,2-a/-s-triaziner
SE395275B (sv) Analogiforfarande for framstellning av aminopyrazolo/3,4-d/pyrimidiner
SE405120B (sv) Analogiforfarande for framstellning av 1-aryl-1,4-bensodiazepin-2,5-dioner