RO62762A - Procede pour la preparation des(1,5a)-pyrimidines 3,5,7-tri-substitues - Google Patents
Procede pour la preparation des(1,5a)-pyrimidines 3,5,7-tri-substituesInfo
- Publication number
- RO62762A RO62762A RO7200073093A RO7309372A RO62762A RO 62762 A RO62762 A RO 62762A RO 7200073093 A RO7200073093 A RO 7200073093A RO 7309372 A RO7309372 A RO 7309372A RO 62762 A RO62762 A RO 62762A
- Authority
- RO
- Romania
- Prior art keywords
- pyrimidines
- tri
- substituted
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20653871A | 1971-12-09 | 1971-12-09 | |
| US245870A US3925385A (en) | 1972-04-20 | 1972-04-20 | 6-Carbethoxy-3,7-disubstitutedpyrazolo{8 1,5a{9 pyrimidines |
| US27346572A | 1972-07-20 | 1972-07-20 | |
| US29984072A | 1972-10-24 | 1972-10-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RO62762A true RO62762A (fr) | 1978-05-15 |
Family
ID=27498614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO7200073093A RO62762A (fr) | 1971-12-09 | 1972-12-09 | Procede pour la preparation des(1,5a)-pyrimidines 3,5,7-tri-substitues |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS4864097A (sv) |
| BE (1) | BE792533A (sv) |
| BG (1) | BG22401A3 (sv) |
| CH (1) | CH603652A5 (sv) |
| DD (1) | DD104530A5 (sv) |
| DE (1) | DE2257547A1 (sv) |
| GB (1) | GB1412017A (sv) |
| HU (1) | HU168530B (sv) |
| IE (1) | IE37189B1 (sv) |
| IL (1) | IL40895A (sv) |
| LU (1) | LU66597A1 (sv) |
| NL (1) | NL7216539A (sv) |
| NO (1) | NO137012C (sv) |
| RO (1) | RO62762A (sv) |
| SE (1) | SE398751B (sv) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4281000A (en) * | 1979-07-09 | 1981-07-28 | American Cyanamid Company | Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents |
| AU557300B2 (en) * | 1982-03-16 | 1986-12-18 | Farmitalia Carlo Erba S.P.A. | Substituted 1h-pyrazolo(1,5-alpha)pyrimidines and processes for their preparation |
| ZA831407B (en) * | 1982-03-25 | 1983-11-30 | Erba Farmitalia | Substituted ethenyl derivatives of 1h-pyrazolo(1,5-a)pyrimidine and process for their preparation |
| NZ208554A (en) * | 1983-06-23 | 1987-06-30 | American Cyanamid Co | (aryl and heteroaryl)-(7-(aryl and heteroaryl)-pyrazolo (1,5-a) pyrimidin-3-yl)-methanone derivatives and pharmaceutical compositions |
| DE3533050A1 (de) * | 1985-09-17 | 1987-03-26 | Basf Ag | 7-amino-azolo(1,5-a)pyrimidine, verfahren zu ihrer herstellung und diese enthaltende fungizide, bzw. deren verwendung als fungizide |
| CA1330079C (en) * | 1988-10-13 | 1994-06-07 | Michihiko Tsujitani | Pyrrolo (3,2-e)pyrazolo(1,5-a)pyrimidine derivative and medicine comprising the same |
| DE69130683T2 (de) * | 1991-04-22 | 1999-05-06 | Otsuka Pharmaceutical Factory, Inc., Naruto, Tokushima | PYRAZOLO[1,5-a]PYRIMIDINDERIVATE UND SIE ENTHALTENDE ANTIINFLAMMATORISCHE MITTEL |
| DE4333705C2 (de) * | 1993-10-02 | 2003-10-30 | Guenter Ege | Arylmethylsubstituierte Pyrazolo-azine, insbesondere 3-Arylmethylpyrazolo[1,5-a]pyrimidine und Verfahren zur Herstellung von 8-Arylmethyl-pyrazolo[5,1-c][1,2,4]triazinen |
| PT714898E (pt) * | 1994-06-21 | 2002-04-29 | Otsuka Pharma Co Ltd | Derivado de pirazolo¬1,5-a|pirimidina |
| KR100260292B1 (ko) * | 1995-09-28 | 2000-07-01 | 오쓰카 요시미쓰 | 진통제 |
| FR2771631B1 (fr) | 1997-12-03 | 2001-02-02 | Oreal | Compositions de teinture des fibres keratiniques contenant des 3-amino pyrazolo-[1,5-a]-pyrimidines, procede de teinture, nouvelles 3-amino pyrazolo- [1,5-a]-pyrimidines et leur procede de preparation |
| US7161003B1 (en) * | 2002-09-04 | 2007-01-09 | Schering Corporation | Pyrazolopyrimidines as cyclin dependent kinase inhibitors |
| NZ539165A (en) * | 2002-09-04 | 2008-03-28 | Schering Corp | Pyrazolopyrimidines as cyclin-dependent kinase inhibitors |
| US7119200B2 (en) * | 2002-09-04 | 2006-10-10 | Schering Corporation | Pyrazolopyrimidines as cyclin dependent kinase inhibitors |
| ES2222813B1 (es) * | 2003-07-24 | 2005-12-16 | Ferrer Internacional, S.A. | N-(3-(3-sustituidas-pirazolo(1,5-a)pirimidin-7-il)-fenil)-sulfonamidas y composiciones y metodos relacionados. |
| TWI252851B (en) * | 2003-07-24 | 2006-04-11 | Ferrer Int | 7-substituted 3-nitro-pyrazolo[1,5-a]pyrimidines and compositions and methods related thereto |
| KR101793807B1 (ko) | 2013-04-25 | 2017-11-03 | 베이진 엘티디 | 단백질 키나제 억제제로서의 융합된 헤테로시클릭 화합물 |
| KR102100419B1 (ko) | 2013-09-13 | 2020-04-14 | 베이진 스위찰랜드 게엠베하 | 항-pd1 항체 및 이의 치료 및 진단 용도 |
| TWI687438B (zh) | 2014-07-03 | 2020-03-11 | 英屬開曼群島商百濟神州生物科技有限公司 | 抗ｐｄ-ｌ１抗體及其作為治療及診斷之用途 |
| WO2018007885A1 (en) | 2016-07-05 | 2018-01-11 | Beigene, Ltd. | COMBINATION OF A PD-l ANTAGONIST AND A RAF INHIBITOR FOR TREATING CANCER |
| MX2019001900A (es) | 2016-08-16 | 2019-07-01 | Beigene Ltd | Forma cristalina de (s)-7-(1-acriloilpiperidin-4-il)-2-(4-fenoxife nil)-4,5,6,7-tetra-hidropirazolo[1,5-a]pirimidin-3-carboxamida, preparacion y usos de la misma. |
| FI3500299T3 (fi) | 2016-08-19 | 2024-02-14 | Beigene Switzerland Gmbh | Tsanubrutinibin yhdistelmä cd20-tai pd-1-vasta-aineen kanssa käytettäväksi syövän hoidossa |
| CN110461847B (zh) | 2017-01-25 | 2022-06-07 | 百济神州有限公司 | (S)-7-(1-(丁-2-炔酰基)哌啶-4-基)-2-(4-苯氧基苯基)-4,5,6,7-四氢吡唑并[1,5-a]嘧啶-3-甲酰胺的结晶形式、其制备及用途 |
| WO2019001417A1 (en) | 2017-06-26 | 2019-01-03 | Beigene, Ltd. | IMMUNOTHERAPY FOR HEPATOCELLULAR CARCINOMA |
| US11377449B2 (en) | 2017-08-12 | 2022-07-05 | Beigene, Ltd. | BTK inhibitors with improved dual selectivity |
| WO2019108795A1 (en) | 2017-11-29 | 2019-06-06 | Beigene Switzerland Gmbh | Treatment of indolent or aggressive b-cell lymphomas using a combination comprising btk inhibitors |
| US11786531B1 (en) | 2022-06-08 | 2023-10-17 | Beigene Switzerland Gmbh | Methods of treating B-cell proliferative disorder |
-
0
- BE BE792533D patent/BE792533A/xx unknown
-
1972
- 1972-11-21 IE IE1612/72A patent/IE37189B1/xx unknown
- 1972-11-22 IL IL40895A patent/IL40895A/en unknown
- 1972-11-23 DE DE2257547A patent/DE2257547A1/de active Pending
- 1972-12-01 GB GB5558772A patent/GB1412017A/en not_active Expired
- 1972-12-05 SE SE7215829A patent/SE398751B/sv unknown
- 1972-12-05 LU LU66597A patent/LU66597A1/xx unknown
- 1972-12-06 NO NO4476/72A patent/NO137012C/no unknown
- 1972-12-06 NL NL7216539A patent/NL7216539A/xx not_active Application Discontinuation
- 1972-12-06 CH CH1775172A patent/CH603652A5/xx not_active IP Right Cessation
- 1972-12-07 DD DD167370A patent/DD104530A5/xx unknown
- 1972-12-08 HU HUIE548A patent/HU168530B/hu unknown
- 1972-12-09 BG BG022071A patent/BG22401A3/xx unknown
- 1972-12-09 RO RO7200073093A patent/RO62762A/ro unknown
- 1972-12-09 JP JP47123877A patent/JPS4864097A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPS4864097A (sv) | 1973-09-05 |
| NL7216539A (sv) | 1973-06-13 |
| DD104530A5 (sv) | 1974-03-12 |
| LU66597A1 (sv) | 1973-03-15 |
| BE792533A (fr) | 1973-06-08 |
| IL40895A (en) | 1976-12-31 |
| NO137012C (no) | 1977-12-14 |
| IE37189L (en) | 1973-06-09 |
| IE37189B1 (en) | 1977-05-25 |
| DE2257547A1 (de) | 1973-06-14 |
| IL40895A0 (en) | 1973-01-30 |
| NO137012B (no) | 1977-09-05 |
| HU168530B (sv) | 1976-05-28 |
| SE398751B (sv) | 1978-01-16 |
| CH603652A5 (sv) | 1978-08-31 |
| BG22401A3 (bg) | 1977-02-20 |
| GB1412017A (en) | 1975-10-29 |
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