JPS4862774A - - Google Patents
Info
- Publication number
- JPS4862774A JPS4862774A JP47121143A JP12114372A JPS4862774A JP S4862774 A JPS4862774 A JP S4862774A JP 47121143 A JP47121143 A JP 47121143A JP 12114372 A JP12114372 A JP 12114372A JP S4862774 A JPS4862774 A JP S4862774A
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/56—One oxygen atom and one sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU64387 | 1971-12-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS4862774A true JPS4862774A (enExample) | 1973-09-01 |
Family
ID=19726894
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP47121143A Pending JPS4862774A (enExample) | 1971-12-02 | 1972-12-02 |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS4862774A (enExample) |
| BE (1) | BE792206A (enExample) |
| DD (1) | DD106646A5 (enExample) |
| DE (1) | DE2258561A1 (enExample) |
| FR (1) | FR2162106A1 (enExample) |
| HU (1) | HU164196B (enExample) |
| IL (1) | IL40971A0 (enExample) |
| LU (1) | LU64387A1 (enExample) |
| NL (1) | NL7216309A (enExample) |
| OA (1) | OA04289A (enExample) |
| ZA (1) | ZA728536B (enExample) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS597174A (ja) * | 1982-06-18 | 1984-01-14 | バイヤ−スドルフ・アクチエンゲゼルシヤフト | 置換された５−フエニルチオ−６−アミノ−ピリミジノン、その製造方法及びその利用ならびにこの化合物を含む調剤 |
| JPS59106472A (ja) * | 1982-11-18 | 1984-06-20 | モンテディソン・エッセ・ピ・ア | 除草活性を有するピリミジン−４−オン誘導体 |
| JPS6172764A (ja) * | 1984-09-17 | 1986-04-14 | Hokuriku Seiyaku Co Ltd | キナゾリノン誘導体 |
| JPS6251672A (ja) * | 1985-08-30 | 1987-03-06 | Masayuki Ishikawa | 新規な２−（４−フエニル−１−ピペラジニルアルキル）アミノピリミジン誘導体及びその酸付加塩 |
| JP2005060401A (ja) * | 2003-08-13 | 2005-03-10 | Syrrx Inc | ジペプチジルペプチダーゼ阻害剤 |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4425143A1 (de) * | 1994-07-15 | 1996-01-18 | Basf Ag | Substituierte Pyrimidinverbindungen und deren Verwendung |
| HUT76266A (en) * | 1995-10-31 | 1997-07-28 | Egyt Gyogyszervegyeszeti Gyar | New piperazinyl-alkylthio-pyrimidine derivatives, pharmaceutical compositions containing them, and process for producing the active components |
| DE19600934A1 (de) | 1996-01-12 | 1997-07-17 | Basf Ag | Substituierte Aza- und Diazacycloheptan- und Cyclooctanverbindungen und deren Verwendung |
| EP1407774A1 (en) * | 2002-09-10 | 2004-04-14 | LION Bioscience AG | 2-Amino-4-quinazolinones as LXR nuclear receptor binding compounds |
| KR20050122220A (ko) | 2003-03-25 | 2005-12-28 | 다케다 샌디에고, 인코포레이티드 | 디펩티딜 펩티다제 억제제 |
| WO2005005395A2 (en) | 2003-07-02 | 2005-01-20 | F. Hoffmann-La Roche Ag | Arylamine-substituted quinazolinone compounds |
| EP1911754B1 (en) * | 2003-08-13 | 2013-10-09 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| WO2005026148A1 (en) | 2003-09-08 | 2005-03-24 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
| MXPA06005686A (es) | 2003-11-20 | 2006-08-17 | Janssen Pharmaceutica Nv | 2-quinolinonas y 2-quinoxalinonas 7-fenilaquilo sustituidas como inhibidores de la poli(adp-ribosa)polimerasa. |
| KR101118582B1 (ko) | 2003-11-20 | 2012-02-27 | 얀센 파마슈티카 엔.브이. | 폴리(ａｄｐ-리보스)폴리머라제 저해제로서의 6-알케닐 및6-페닐알킬 치환된 2-퀴놀리논 및 2-퀴녹살리논 |
| MXPA06010571A (es) | 2004-03-15 | 2007-02-16 | Takeda Pharmaceutical | Inhibidores de dipeptidil peptidasa. |
| EA012837B1 (ru) | 2004-06-30 | 2009-12-30 | Янссен Фармацевтика Н.В. | Производные хиназолинона в качестве ингибиторов parp |
| ES2415771T3 (es) | 2004-06-30 | 2013-07-26 | Janssen Pharmaceutica N.V. | Derivados de quinazolina como inhibidores de PARP |
| CN1980674B (zh) | 2004-06-30 | 2011-05-25 | 詹森药业有限公司 | 作为parp抑制剂的2,3-二氮杂萘衍生物 |
| FR2877005A1 (fr) * | 2004-10-22 | 2006-04-28 | Bioprojet Soc Civ Ile | Nouveaux derives d'arylpiperazine |
| EP1828192B1 (en) | 2004-12-21 | 2014-12-03 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| MX2007008233A (es) * | 2005-01-07 | 2007-09-11 | Esteve Labor Dr | Compuestos de 2-amino-quinazolin-4-cianato sustituidos para el uso en el tratamiento de trastornos del cns, dolor, apoplejia, adiccion y epilepsia, su preparacion y uso como intermediarios. |
| PL1942898T5 (pl) | 2005-09-14 | 2014-10-31 | Takeda Pharmaceuticals Co | Inhibitory peptydazy dipeptydylowej do leczenia cukrzycy |
| WO2007035629A2 (en) | 2005-09-16 | 2007-03-29 | Takeda Pharmaceutical Company Limited | Process for the preparation of pyrimidinedione derivatives |
| US8324383B2 (en) | 2006-09-13 | 2012-12-04 | Takeda Pharmaceutical Company Limited | Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile |
| TW200838536A (en) | 2006-11-29 | 2008-10-01 | Takeda Pharmaceutical | Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor |
| ATE542799T1 (de) | 2007-03-08 | 2012-02-15 | Janssen Pharmaceutica Nv | Chinolinonderivate als parp und tank-inhibitoren |
| US8093236B2 (en) | 2007-03-13 | 2012-01-10 | Takeda Pharmaceuticals Company Limited | Weekly administration of dipeptidyl peptidase inhibitors |
| EP2215075B1 (en) | 2007-10-26 | 2013-12-11 | Janssen Pharmaceutica, N.V. | Quinolinone derivatives as parp inhibitors |
| EP2260026B1 (en) | 2008-03-27 | 2011-06-22 | Janssen Pharmaceutica, N.V. | Quinazolinone derivatives as tubulin polymerization inhibitors |
| EP2271626B1 (en) | 2008-03-27 | 2014-11-26 | Janssen Pharmaceutica, N.V. | Tetrahydrophenanthridinones and tetrahydrocyclopentaquinolinones as parp and tubulin polymerization inhibitors |
| CN107226808B (zh) * | 2016-03-23 | 2021-01-01 | 北京四环制药有限公司 | 端锚聚合酶抑制剂 |
-
0
- BE BE792206D patent/BE792206A/xx unknown
-
1971
- 1971-12-02 LU LU64387A patent/LU64387A1/xx unknown
-
1972
- 1972-11-30 IL IL40971A patent/IL40971A0/xx unknown
- 1972-11-30 FR FR7242607A patent/FR2162106A1/fr not_active Withdrawn
- 1972-11-30 DD DD167200A patent/DD106646A5/xx unknown
- 1972-11-30 HU HUBI460A patent/HU164196B/hu unknown
- 1972-11-30 OA OA54767A patent/OA04289A/xx unknown
- 1972-11-30 DE DE19722258561 patent/DE2258561A1/de active Pending
- 1972-12-01 NL NL7216309A patent/NL7216309A/xx unknown
- 1972-12-01 ZA ZA728536A patent/ZA728536B/xx unknown
- 1972-12-02 JP JP47121143A patent/JPS4862774A/ja active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS597174A (ja) * | 1982-06-18 | 1984-01-14 | バイヤ−スドルフ・アクチエンゲゼルシヤフト | 置換された５−フエニルチオ−６−アミノ−ピリミジノン、その製造方法及びその利用ならびにこの化合物を含む調剤 |
| JPS59106472A (ja) * | 1982-11-18 | 1984-06-20 | モンテディソン・エッセ・ピ・ア | 除草活性を有するピリミジン−４−オン誘導体 |
| JPS6172764A (ja) * | 1984-09-17 | 1986-04-14 | Hokuriku Seiyaku Co Ltd | キナゾリノン誘導体 |
| JPS6251672A (ja) * | 1985-08-30 | 1987-03-06 | Masayuki Ishikawa | 新規な２−（４−フエニル−１−ピペラジニルアルキル）アミノピリミジン誘導体及びその酸付加塩 |
| JP2005060401A (ja) * | 2003-08-13 | 2005-03-10 | Syrrx Inc | ジペプチジルペプチダーゼ阻害剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| BE792206A (enExample) | 1973-06-01 |
| NL7216309A (enExample) | 1973-06-05 |
| DD106646A5 (enExample) | 1974-06-20 |
| ZA728536B (en) | 1973-09-26 |
| LU64387A1 (enExample) | 1973-07-16 |
| FR2162106A1 (en) | 1973-07-13 |
| OA04289A (fr) | 1979-12-31 |
| IL40971A0 (en) | 1973-01-30 |
| HU164196B (enExample) | 1974-01-28 |
| DE2258561A1 (de) | 1973-06-20 |