IL40971A0 - Substituted pyrimidone-(4) derivatives,a method for producing them and medicaments containing them - Google Patents

Substituted pyrimidone-(4) derivatives,a method for producing them and medicaments containing them

Info

Publication number
IL40971A0
IL40971A0 IL40971A IL4097172A IL40971A0 IL 40971 A0 IL40971 A0 IL 40971A0 IL 40971 A IL40971 A IL 40971A IL 4097172 A IL4097172 A IL 4097172A IL 40971 A0 IL40971 A0 IL 40971A0
Authority
IL
Israel
Prior art keywords
derivatives
producing
medicaments containing
substituted pyrimidone
pyrimidone
Prior art date
Application number
IL40971A
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of IL40971A0 publication Critical patent/IL40971A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56—One oxygen atom and one sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL40971A 1971-12-02 1972-11-30 Substituted pyrimidone-(4) derivatives,a method for producing them and medicaments containing them IL40971A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU64387 1971-12-02

Publications (1)

Publication Number Publication Date
IL40971A0 true IL40971A0 (en) 1973-01-30

Family

ID=19726894

Family Applications (1)

Application Number Title Priority Date Filing Date
IL40971A IL40971A0 (en) 1971-12-02 1972-11-30 Substituted pyrimidone-(4) derivatives,a method for producing them and medicaments containing them

Country Status (11)

Country Link
JP (1) JPS4862774A (en)
BE (1) BE792206A (en)
DD (1) DD106646A5 (en)
DE (1) DE2258561A1 (en)
FR (1) FR2162106A1 (en)
HU (1) HU164196B (en)
IL (1) IL40971A0 (en)
LU (1) LU64387A1 (en)
NL (1) NL7216309A (en)
OA (1) OA04289A (en)
ZA (1) ZA728536B (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3222914A1 (en) * 1982-06-18 1983-12-22 Beiersdorf Ag, 2000 Hamburg SUBSTITUTED 5-PHENYLTHIO-6-AMINO-PYRIMIDINONE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE, AND PREPARATIONS CONTAINING THESE COMPOUNDS
IT1153066B (en) * 1982-11-18 1987-01-14 Mentedison S P A HERBICIDE ACTIVITIES OF PIRIMIDIN-4-ONE
JPS6172764A (en) * 1984-09-17 1986-04-14 Hokuriku Seiyaku Co Ltd Quinazolinone derivative
JPH0696561B2 (en) * 1985-08-30 1994-11-30 正幸 石川 Novel 2- (4-phenyl-1-piperazinylalkyl) aminopyrimidine derivative and acid addition salt thereof
DE4425143A1 (en) * 1994-07-15 1996-01-18 Basf Ag Substituted pyrimidine compounds and their use
HUT76266A (en) * 1995-10-31 1997-07-28 Egyt Gyogyszervegyeszeti Gyar New piperazinyl-alkylthio-pyrimidine derivatives, pharmaceutical compositions containing them, and process for producing the active components
DE19600934A1 (en) 1996-01-12 1997-07-17 Basf Ag Substituted aza and diazacycloheptane and cyclooctane compounds and their use
EP1407774A1 (en) * 2002-09-10 2004-04-14 LION Bioscience AG 2-Amino-4-quinazolinones as LXR nuclear receptor binding compounds
US20040242568A1 (en) 2003-03-25 2004-12-02 Syrrx, Inc. Dipeptidyl peptidase inhibitors
EP1644369A2 (en) 2003-07-02 2006-04-12 F. Hoffmann-La Roche Ag Arylamine-substituted quinazolinone compounds
EP1506967B1 (en) 2003-08-13 2007-11-21 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
EP1911754B1 (en) * 2003-08-13 2013-10-09 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
EP1699777B1 (en) 2003-09-08 2012-12-12 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
ES2551027T3 (en) 2003-11-20 2015-11-13 Janssen Pharmaceutica Nv Substituted 7-phenylalkyl 2-quinolinones and 2-quinoxalinones as poly (ADP-ribose) polymerase inhibitors
EA009875B1 (en) 2003-11-20 2008-04-28 Янссен Фармацевтика Н.В. 6-alkenyl and 6-phenylalkyl substituted 2-quinolinones and 2-quinoxalinones as poly(adp-ribose) polymerase inhibitors
MXPA06010571A (en) 2004-03-15 2007-02-16 Takeda Pharmaceutical DIPEPTIDIL PEPTIDASA INHIBITORS.
CN1980913B (en) 2004-06-30 2011-12-14 詹森药业有限公司 quinazolinedione derivatives as PARP inhibitors
KR101286969B1 (en) 2004-06-30 2013-07-23 얀센 파마슈티카 엔.브이. Quinazolinone derivatives as parp inhibitors
ES2563954T3 (en) 2004-06-30 2016-03-16 Janssen Pharmaceutica Nv Phthalazine derivatives as PARP inhibitors
FR2877005A1 (en) * 2004-10-22 2006-04-28 Bioprojet Soc Civ Ile NEW ARYLPIPERAZINE DERIVATIVES
EP1828192B1 (en) 2004-12-21 2014-12-03 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
EP1841746A1 (en) * 2005-01-07 2007-10-10 Laboratorios Del Dr. Esteve, S.A. Substituted 2-amino-quinazolin-4-on compoundsfor use in the treatment of cns disorders, pain, stroke, addicition and epilepsy, their preparation and use as intermediates
ME02005B (en) 2005-09-14 2012-08-31 Takeda Pharmaceuticals Co Dipeptidyl peptidase inhibitors for treating diabetes
CN101360723A (en) 2005-09-16 2009-02-04 武田药品工业株式会社 Process for preparing pyrimidinedione derivatives
US8324383B2 (en) 2006-09-13 2012-12-04 Takeda Pharmaceutical Company Limited Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile
TW200838536A (en) 2006-11-29 2008-10-01 Takeda Pharmaceutical Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
SI2134691T1 (en) 2007-03-08 2012-06-29 Janssen Pharmaceutica Nv Quinolinone derivatives as parp and tank inhibitors
US8093236B2 (en) 2007-03-13 2012-01-10 Takeda Pharmaceuticals Company Limited Weekly administration of dipeptidyl peptidase inhibitors
PL2215075T3 (en) 2007-10-26 2014-04-30 Janssen Pharmaceutica Nv Quinolinone derivatives as parp inhibitors
RU2490260C2 (en) 2008-03-27 2013-08-20 Янссен Фармацевтика Нв Tetrahydrophenantridiones and tetrahydrocyclopentaquinolinones as parp inhibitors and tubulin polymerisation inhibitors
AU2009228945B2 (en) 2008-03-27 2013-05-02 Janssen Pharmaceutica Nv Quinazolinone derivatives as tubulin polymerization inhibitors
CN107226808B (en) * 2016-03-23 2021-01-01 北京四环制药有限公司 Tankyrase inhibitors

Also Published As

Publication number Publication date
DD106646A5 (en) 1974-06-20
LU64387A1 (en) 1973-07-16
ZA728536B (en) 1973-09-26
FR2162106A1 (en) 1973-07-13
DE2258561A1 (en) 1973-06-20
NL7216309A (en) 1973-06-05
HU164196B (en) 1974-01-28
JPS4862774A (en) 1973-09-01
BE792206A (en) 1973-06-01
OA04289A (en) 1979-12-31

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