JPS4834864A - - Google Patents

Info

Publication number
JPS4834864A
JPS4834864A JP47089161A JP8916172A JPS4834864A JP S4834864 A JPS4834864 A JP S4834864A JP 47089161 A JP47089161 A JP 47089161A JP 8916172 A JP8916172 A JP 8916172A JP S4834864 A JPS4834864 A JP S4834864A
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP47089161A
Other languages
Japanese (ja)
Other versions
JPS5310596B2 (sv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS4834864A publication Critical patent/JPS4834864A/ja
Publication of JPS5310596B2 publication Critical patent/JPS5310596B2/ja
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/36Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/16Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/28Morphinans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/26Phenanthrenes; Hydrogenated phenanthrenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP8916172A 1971-09-08 1972-09-07 Expired JPS5310596B2 (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17883771A 1971-09-08 1971-09-08
US00217633A US3819635A (en) 1971-09-08 1972-01-13 14-hydroxymorphinan derivatives

Publications (2)

Publication Number Publication Date
JPS4834864A true JPS4834864A (sv) 1973-05-22
JPS5310596B2 JPS5310596B2 (sv) 1978-04-14

Family

ID=26874723

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8916172A Expired JPS5310596B2 (sv) 1971-09-08 1972-09-07

Country Status (19)

Country Link
US (1) US3819635A (sv)
JP (1) JPS5310596B2 (sv)
AU (1) AU470102B2 (sv)
BE (1) BE788478A (sv)
CA (1) CA999578A (sv)
CH (1) CH590845A5 (sv)
CY (1) CY980A (sv)
DD (1) DD100255A5 (sv)
DE (3) DE2243961A1 (sv)
DK (1) DK141624B (sv)
FR (1) FR2154481B1 (sv)
GB (2) GB1412130A (sv)
HK (1) HK2679A (sv)
IE (2) IE36687B1 (sv)
KE (1) KE2911A (sv)
MY (1) MY7900027A (sv)
NL (1) NL162072C (sv)
SE (2) SE398877B (sv)
YU (1) YU45099B (sv)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60185765A (ja) * 1976-03-23 1985-09-21 ブリストル マイヤ−ズ カンパニ− ヒドロキシモルフィナン誘導体の製造法

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3910920A (en) * 1973-11-07 1975-10-07 Bristol Myers Co 3,14,17-Substituted-6,7-tetramethylenemorphinans
US3980641A (en) * 1975-07-31 1976-09-14 Bristol-Myers Company Process for the preparation of 14-hydroxymorphinans
US4017497A (en) * 1975-11-18 1977-04-12 Bristol-Myers Company Process for the preparation of 14-hydroxymorphinan derivatives
JPS52136176A (en) * 1976-03-23 1977-11-14 Bristol Myers Co Method of improving 144hydroxymorphinan derivatives
US4139534A (en) * 1977-02-17 1979-02-13 Bristol-Myers Company Process for the preparation of 14-hydroxymorphinan derivatives
US4052389A (en) * 1976-03-23 1977-10-04 Bristol-Myers Company Derivatives of 9,10-dihydroxy-1-(p-alkoxybenzyl)-perhydroisoquinoline oxazine-3-one
GB1587831A (en) * 1977-03-23 1981-04-08 Reckitt & Colmann Prod Ltd Morphine derivatives
GB1593191A (en) * 1977-03-23 1981-07-15 Reckitt & Colmann Prod Ltd Derivatives of morphine
US4115389A (en) * 1977-05-02 1978-09-19 Bristol-Myers Company Process of N-demethylating (-)-1-(p-methoxybenzyl)-2-methyl-1,2,3,4,5,6,7,8-octahydroisoquinoline
US4338320A (en) * 1978-11-15 1982-07-06 The Board Of Regents Of The University Of Nebraska Esters of 6'-hydroxycinchonine, and a method of treating arrythmia with them
US4228285A (en) * 1979-02-28 1980-10-14 Bristol-Myers Company 14-Hydroxy-6-oxamorphinans and 14-hydroxy-6-oxaisomorphinans
US4272540A (en) * 1979-04-24 1981-06-09 Sisa, Incorporated 14-Methoxymorphinan-6-one compounds and therapeutic methods of treating pain and drug dependence with them
US4322427A (en) * 1981-04-16 1982-03-30 Bristol-Myers Company Analgetic compositions and methods of use
CA2144770C (en) * 1993-07-19 2006-02-28 Hiroshi Nagase Brain cell protective agent
WO1995003308A1 (en) * 1993-07-23 1995-02-02 Toray Industries, Inc. Morphinan derivative and medicinal use
CZ281174B6 (cs) * 1993-08-13 1996-07-17 Galena, A.S. Způsob přípravy 3,14ß-dihydroxy-17-normorfinanu
AU753278B2 (en) 1998-02-25 2002-10-10 Abbott Laboratories Butorphanol sustained release formulations
US20040167164A1 (en) * 1998-05-05 2004-08-26 Jose Pozuelo Compositions and methods for treating particular chemical addictions and mental illnesses
US7923454B2 (en) 2002-05-17 2011-04-12 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
US7501433B2 (en) * 2002-05-17 2009-03-10 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
MXPA04011327A (es) 2002-05-17 2005-08-15 Jenken Biosciences Inc Opioides y compuestos similares a opioides y usos de los mismos.
US8017622B2 (en) * 2003-05-16 2011-09-13 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
CN103073496B (zh) * 2013-02-18 2015-08-26 苏州立新制药有限公司 右美沙芬的制备方法
EP3207923B1 (en) 2014-10-14 2019-09-04 Hisamitsu Pharmaceutical Co., Inc. Adhesive patch

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3166559A (en) * 1965-01-19 J-lower alkoxy-x-phenyloxy-ix-hydroxy-
GB1028407A (en) * 1962-04-06 1966-05-04 Shionogi & Co Improvements in or relating to morphinan derivatives and their preparation
FR1362540A (fr) * 1963-04-05 1964-06-05 Shionogi & Co Dérivés n substitués du morphinane et leur production

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60185765A (ja) * 1976-03-23 1985-09-21 ブリストル マイヤ−ズ カンパニ− ヒドロキシモルフィナン誘導体の製造法

Also Published As

Publication number Publication date
DE2265256A1 (de) 1977-01-27
CY980A (en) 1979-03-23
DE2243961A1 (de) 1973-04-05
DK141624C (sv) 1980-10-13
US3819635A (en) 1974-06-25
DE2265255A1 (de) 1977-01-27
IE36688B1 (en) 1977-02-02
KE2911A (en) 1979-01-26
AU4622872A (en) 1974-03-07
DK141624B (da) 1980-05-12
NL7212176A (sv) 1973-03-12
DD100255A5 (sv) 1973-09-12
SE403286B (sv) 1978-08-07
CH590845A5 (sv) 1977-08-31
GB1412130A (en) 1975-10-29
YU227772A (en) 1982-02-28
NL162072B (nl) 1979-11-15
NL162072C (nl) 1980-04-15
SE398877B (sv) 1978-01-23
FR2154481A1 (sv) 1973-05-11
CA999578A (en) 1976-11-09
DE2243961C2 (sv) 1988-07-21
AU470102B2 (en) 1976-03-04
HK2679A (en) 1979-01-19
FR2154481B1 (sv) 1976-04-23
DE2265255C2 (de) 1986-06-05
DE2265256C2 (de) 1985-10-24
IE36687L (en) 1973-03-08
IE36687B1 (en) 1977-02-02
SE7506292L (sv) 1975-06-02
MY7900027A (en) 1979-12-31
JPS5310596B2 (sv) 1978-04-14
GB1412129A (en) 1975-10-29
BE788478A (fr) 1973-03-06
YU45099B (sh) 1992-07-20

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