JPH1160551A5 - - Google Patents
Info
- Publication number
- JPH1160551A5 JPH1160551A5 JP1998162706A JP16270698A JPH1160551A5 JP H1160551 A5 JPH1160551 A5 JP H1160551A5 JP 1998162706 A JP1998162706 A JP 1998162706A JP 16270698 A JP16270698 A JP 16270698A JP H1160551 A5 JPH1160551 A5 JP H1160551A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- phenyl
- integer
- substituted
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19719621A DE19719621A1 (de) | 1997-05-09 | 1997-05-09 | Sulfonylaminocarbonsäuren |
| DE19719621:7 | 1997-05-09 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPH1160551A JPH1160551A (ja) | 1999-03-02 |
| JPH1160551A5 true JPH1160551A5 (https=) | 2005-09-29 |
| JP4177483B2 JP4177483B2 (ja) | 2008-11-05 |
Family
ID=7829102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP16270698A Expired - Fee Related JP4177483B2 (ja) | 1997-05-09 | 1998-05-08 | スルホニルアミノカルボン酸 |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US6451824B1 (https=) |
| EP (1) | EP0877018B1 (https=) |
| JP (1) | JP4177483B2 (https=) |
| KR (1) | KR100572494B1 (https=) |
| CN (1) | CN1280267C (https=) |
| AR (1) | AR012674A1 (https=) |
| AT (1) | ATE238984T1 (https=) |
| AU (1) | AU732723B2 (https=) |
| BR (1) | BR9801606B1 (https=) |
| CA (1) | CA2237099C (https=) |
| CZ (1) | CZ295527B6 (https=) |
| DE (2) | DE19719621A1 (https=) |
| DK (1) | DK0877018T3 (https=) |
| ES (1) | ES2195220T3 (https=) |
| HU (1) | HU224959B1 (https=) |
| ID (1) | ID20807A (https=) |
| PL (1) | PL191876B1 (https=) |
| PT (1) | PT877018E (https=) |
| RU (1) | RU2193027C2 (https=) |
| TR (1) | TR199800815A2 (https=) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4750272B2 (ja) * | 1998-02-04 | 2011-08-17 | ノバルティス アーゲー | マトリックス分解メタロプロテイナーゼを阻害するスルホニルアミノ誘導体 |
| US6410580B1 (en) | 1998-02-04 | 2002-06-25 | Novartis Ag | Sulfonylamino derivatives which inhibit matrix-degrading metalloproteinases |
| AU754050B2 (en) | 1998-07-16 | 2002-10-31 | Sanofi-Aventis Deutschland Gmbh | Phosphinous and phosphonic acid derivatives used as medicaments |
| DE19851184A1 (de) * | 1998-11-06 | 2000-05-11 | Aventis Pharma Gmbh | N-Arylsulfonyl-aminosäure-omega-amide |
| US6420396B1 (en) * | 1998-12-16 | 2002-07-16 | Beiersdorf Ag | Biphenyl and biphenyl-analogous compounds as integrin antagonists |
| US6677360B2 (en) | 1998-12-16 | 2004-01-13 | Bayer Aktiengesellschaft | Biphenyl and biphenyl-analogous compounds as integrin antagonists |
| US6492394B1 (en) * | 1998-12-22 | 2002-12-10 | Syntex (U.S.A.) Llc | Sulfonamide hydroxamates |
| MXPA01008857A (es) | 1999-03-03 | 2002-07-02 | Procter & Gamble | Inhibidores de metaloproteasa dihetero sustituidos. |
| WO2000058278A1 (fr) * | 1999-03-26 | 2000-10-05 | Shionogi & Co., Ltd. | Derives d'acides amines $g(b) |
| GB9918684D0 (en) | 1999-08-09 | 1999-10-13 | Novartis Ag | Organic compounds |
| NZ520656A (en) * | 2000-03-21 | 2004-05-28 | Procter & Gamble | Heterocyclic side chain containing metalloprotease inhibitors |
| WO2001070693A2 (en) | 2000-03-21 | 2001-09-27 | The Procter & Gamble Company | Difluorobutyric acid derivatives and their use as metalloprotease inhibitors |
| NZ520657A (en) * | 2000-03-21 | 2004-11-26 | Procter & Gamble | Heterocyclic side chain containing, N-substituted metalloprotease inhibitors |
| CN1366524A (zh) * | 2000-04-07 | 2002-08-28 | 三星电子株式会社 | 磺胺衍生物作为基质金属蛋白酶抑制剂 |
| GB0103303D0 (en) | 2001-02-09 | 2001-03-28 | Novartis Ag | Organic compounds |
| PA8557501A1 (es) | 2001-11-12 | 2003-06-30 | Pfizer Prod Inc | Benzamida, heteroarilamida y amidas inversas |
| WO2003042190A1 (en) | 2001-11-12 | 2003-05-22 | Pfizer Products Inc. | N-alkyl-adamantyl derivatives as p2x7-receptor antagonists |
| PE20030701A1 (es) | 2001-12-20 | 2003-08-21 | Schering Corp | Compuestos para el tratamiento de trastornos inflamatorios |
| US7071223B1 (en) | 2002-12-31 | 2006-07-04 | Pfizer, Inc. | Benzamide inhibitors of the P2X7 receptor |
| PA8591801A1 (es) | 2002-12-31 | 2004-07-26 | Pfizer Prod Inc | Inhibidores benzamidicos del receptor p2x7. |
| ATE355273T1 (de) * | 2003-05-12 | 2006-03-15 | Pfizer Prod Inc | Benzamidinhibitoren des p2x7-rezeptors |
| EP1493740A1 (fr) * | 2003-07-03 | 2005-01-05 | Warner-Lambert Company LLC | Dérivés de 5-fluoro-thiophene, leur procédé de preparation, les compositions pharmaceutiques les contenant et leur utilisation comme inhibiteurs de métalloprotéinases |
| US7618981B2 (en) * | 2004-05-06 | 2009-11-17 | Cytokinetics, Inc. | Imidazopyridinyl-benzamide anti-cancer agents |
| GB0412553D0 (en) * | 2004-06-04 | 2004-07-07 | Univ Aberdeen | Therapeutic agents for the treatment of bone conditions |
| WO2006003500A1 (en) * | 2004-06-29 | 2006-01-12 | Pfizer Products Inc. | Method for preparing 5-`4-(2-hydroxy-propyl)-3,5-dioxo-4,5-dihydro-3h`1,2,4!triazin-2-yl!-benzamide derivatives by deprotecting the hydroxyl-protected precursers |
| MXPA06015273A (es) * | 2004-06-29 | 2007-03-15 | Pfizer Prod Inc | Procedimiento para preparar derivados de 5-[4-(2-hidroxi -etil)-3, 5-dioxo-4, 5-dihidro-3h-[1, 2, 4]-triazin -2-il]-benzamida con actividad inhibidora de p2x7 mediante reaccion del derivado no sustituido en posicion 4 de la triazina con un oxirano en |
| EP1763353A1 (en) * | 2004-06-29 | 2007-03-21 | Warner-Lambert Company LLC | COMBINATION THERAPIES UTILIZING BENZAMIDE INHIBITORS OF THE P2X<sb>7</sb> RECEPTOR |
| US7576222B2 (en) | 2004-12-28 | 2009-08-18 | Wyeth | Alkynyl-containing tryptophan derivative inhibitors of TACE/matrix metalloproteinase |
| GB0705400D0 (en) | 2007-03-21 | 2007-05-02 | Univ Aberdeen | Therapeutic compounds andm their use |
| SA08290668B1 (ar) * | 2007-10-25 | 2012-02-12 | شيونوجي آند كو.، ليمتد | مشتقات أمين لها نشاط مضاد لمستقبل npy y5 واستخداماتها |
| GB0817207D0 (en) | 2008-09-19 | 2008-10-29 | Pimco 2664 Ltd | therapeutic apsac compounds and their use |
| GB0817208D0 (en) | 2008-09-19 | 2008-10-29 | Pimco 2664 Ltd | Therapeutic apsap compounds and their use |
| US8765953B2 (en) * | 2008-12-23 | 2014-07-01 | Aquilus Pharmaceuticals, Inc. | Compounds and methods for the treatment of pain and other diseases |
| GB201311361D0 (en) | 2013-06-26 | 2013-08-14 | Pimco 2664 Ltd | Compounds and their therapeutic use |
| AU2015367528B2 (en) | 2014-12-17 | 2020-05-14 | Pimco 2664 Limited | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and N-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)-benzenesulfonamide compounds and their therapeutic use |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2764262B2 (ja) * | 1987-08-28 | 1998-06-11 | 持田製薬株式会社 | ヒダントイン誘導体及びそれを有効成分とする医薬組成物 |
| TW201303B (https=) * | 1990-07-05 | 1993-03-01 | Hoffmann La Roche | |
| GB9200210D0 (en) * | 1992-01-07 | 1992-02-26 | British Bio Technology | Compounds |
| US5455258A (en) * | 1993-01-06 | 1995-10-03 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamic acids |
| US5506242A (en) * | 1993-01-06 | 1996-04-09 | Ciba-Geigy Corporation | Arylsufonamido-substituted hydroxamic acids |
| CA2193691A1 (en) * | 1994-06-22 | 1995-12-28 | Andrew Miller | Metalloproteinase inhibitors |
| US5863949A (en) * | 1995-03-08 | 1999-01-26 | Pfizer Inc | Arylsulfonylamino hydroxamic acid derivatives |
| ES2153031T4 (es) * | 1995-04-20 | 2001-05-16 | Pfizer | Derivados del acido arilsulfonil hidroxamico como inhibidores de mmp y tnf. |
| KR980009238A (ko) * | 1995-07-28 | 1998-04-30 | 우에노 도시오 | 설포닐아미노산 유도체 |
| SK282833B6 (sk) * | 1995-11-17 | 2002-12-03 | Warner-Lambert Company | Sulfónamidové inhibítory matricových metaloproteináz a farmaceutická kompozícia obsahujúca tieto inhibítory |
| BR9707010B1 (pt) * | 1996-01-23 | 2009-05-05 | compostos, composição farmacêutica e composições para inibir metaloproteinase e colagenase do tipo iv. | |
| CA2242416C (en) * | 1996-01-23 | 2006-03-21 | Shionogi & Co., Ltd. | Sulfonated amino acid derivatives and metalloproteinase inhibitors containing the same |
| CN1077885C (zh) * | 1996-05-17 | 2002-01-16 | 沃尼尔·朗伯公司 | 联苯基磺酰胺基质金属蛋白酶抑制剂 |
| US5756545A (en) * | 1997-04-21 | 1998-05-26 | Warner-Lambert Company | Biphenysulfonamide matrix metal alloproteinase inhibitors |
| PT877019E (pt) * | 1997-05-09 | 2002-05-31 | Hoechst Ag | Acidos diaminocarboxilicos substituidos |
-
1997
- 1997-05-09 DE DE19719621A patent/DE19719621A1/de not_active Withdrawn
-
1998
- 1998-05-02 EP EP98108038A patent/EP0877018B1/de not_active Expired - Lifetime
- 1998-05-02 AT AT98108038T patent/ATE238984T1/de active
- 1998-05-02 DE DE59808121T patent/DE59808121D1/de not_active Expired - Lifetime
- 1998-05-02 PT PT98108038T patent/PT877018E/pt unknown
- 1998-05-02 ES ES98108038T patent/ES2195220T3/es not_active Expired - Lifetime
- 1998-05-02 DK DK98108038T patent/DK0877018T3/da active
- 1998-05-07 AR ARP980102139A patent/AR012674A1/es active IP Right Grant
- 1998-05-07 TR TR1998/00815A patent/TR199800815A2/xx unknown
- 1998-05-07 CA CA2237099A patent/CA2237099C/en not_active Expired - Fee Related
- 1998-05-07 CZ CZ19981438A patent/CZ295527B6/cs not_active IP Right Cessation
- 1998-05-07 ID IDP980667A patent/ID20807A/id unknown
- 1998-05-08 BR BRPI9801606-7A patent/BR9801606B1/pt not_active IP Right Cessation
- 1998-05-08 JP JP16270698A patent/JP4177483B2/ja not_active Expired - Fee Related
- 1998-05-08 PL PL326216A patent/PL191876B1/pl not_active IP Right Cessation
- 1998-05-08 HU HU9801044A patent/HU224959B1/hu not_active IP Right Cessation
- 1998-05-08 KR KR1019980016385A patent/KR100572494B1/ko not_active Expired - Fee Related
- 1998-05-08 US US09/074,693 patent/US6451824B1/en not_active Expired - Lifetime
- 1998-05-08 RU RU98108979/04A patent/RU2193027C2/ru not_active IP Right Cessation
- 1998-05-08 AU AU64823/98A patent/AU732723B2/en not_active Ceased
- 1998-05-08 CN CNB981152651A patent/CN1280267C/zh not_active Expired - Fee Related
-
2002
- 2002-06-13 US US10/170,870 patent/US7160903B2/en not_active Expired - Fee Related
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