JPH11515002A - 副甲状腺ホルモンを含む安定な医薬投与形態 - Google Patents

副甲状腺ホルモンを含む安定な医薬投与形態

Info

Publication number
JPH11515002A
JPH11515002A JP9515527A JP51552797A JPH11515002A JP H11515002 A JPH11515002 A JP H11515002A JP 9515527 A JP9515527 A JP 9515527A JP 51552797 A JP51552797 A JP 51552797A JP H11515002 A JPH11515002 A JP H11515002A
Authority
JP
Japan
Prior art keywords
acid
pharmaceutical preparation
preparation according
amino acids
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP9515527A
Other languages
English (en)
Japanese (ja)
Inventor
ブエレン，ヘンドリク フォン
ガベル，ロルフ−ディエテル
ローデル，ボルフガンク
ブーク，ハインリヒ
Original Assignee
ロシュ ダイアグノスティクス ゲゼルシャフト ミット ベシュレンクテル ハフツング
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ロシュ ダイアグノスティクス ゲゼルシャフト ミット ベシュレンクテル ハフツング filed Critical ロシュ ダイアグノスティクス ゲゼルシャフト ミット ベシュレンクテル ハフツング
Publication of JPH11515002A publication Critical patent/JPH11515002A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP9515527A 1995-10-17 1996-10-17 副甲状腺ホルモンを含む安定な医薬投与形態 Pending JPH11515002A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19538687A DE19538687A1 (de) 1995-10-17 1995-10-17 Stabile pharmazeutische Darreichungsformen enthaltend Parathormon
DE19538687.6 1995-10-17
PCT/EP1996/004503 WO1997014429A1 (de) 1995-10-17 1996-10-17 Stabile pharmazeutische darreichungsformen enthaltend parathormon

Publications (1)

Publication Number Publication Date
JPH11515002A true JPH11515002A (ja) 1999-12-21

Family

ID=7775105

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9515527A Pending JPH11515002A (ja) 1995-10-17 1996-10-17 副甲状腺ホルモンを含む安定な医薬投与形態

Country Status (14)

Country Link
EP (1) EP0855917A1 (cs)
JP (1) JPH11515002A (cs)
KR (1) KR19990064322A (cs)
AU (1) AU7294196A (cs)
BR (1) BR9610983A (cs)
CA (1) CA2234724A1 (cs)
CZ (1) CZ108398A3 (cs)
DE (1) DE19538687A1 (cs)
HU (1) HUP9900751A3 (cs)
NZ (1) NZ320237A (cs)
SK (1) SK47298A3 (cs)
TR (1) TR199800690T1 (cs)
WO (1) WO1997014429A1 (cs)
ZA (1) ZA968715B (cs)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004075913A1 (ja) * 2003-02-28 2004-09-10 Chugai Seiyaku Kabushiki Kaisha タンパク質含有安定化製剤
JP2008542364A (ja) * 2005-06-03 2008-11-27 モガム バイオテクノロジー リサーチ インスティチュート 副甲状腺ホルモン、緩衝液、および安定剤を含んでなる安定化された副甲状腺ホルモン組成物
JP2011251988A (ja) * 2000-02-08 2011-12-15 Allergan Inc ボツリヌス毒素医薬組成物
JP2015134795A (ja) * 2009-06-26 2015-07-27 ラボラトワール、フランセ、デュ、フラクショヌマン、エ、デ、ビオテクノロジＬａｂｏｒａｔｏｉｒｅ Ｆｒａｎｃａｉｓ Ｄｕ Ｆｒａｃｔｉｏｎｎｅｍｅｎｔ Ｅｔ Ｄｅｓ Ｂｉｏｔｅｃｈｎｏｌｏｇｉｅｓ 第ｖｉｉ因子組成物
JP2017061424A (ja) * 2015-09-25 2017-03-30 ニプロ株式会社 液体組成物及び凍結乾燥製剤
JP2021088606A (ja) * 2017-09-22 2021-06-10 旭化成ファーマ株式会社 安定性に優れるテリパラチド含有液状医薬組成物
JP6947946B1 (ja) * 2020-05-11 2021-10-13 旭化成ファーマ株式会社 テリパラチド又はその塩を含有する安定な液状医薬製剤
WO2021229835A1 (ja) * 2020-05-11 2021-11-18 旭化成ファーマ株式会社 テリパラチド又はその塩を含有する安定な液状医薬製剤

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19539574A1 (de) 1995-10-25 1997-04-30 Boehringer Mannheim Gmbh Zubereitungen und Verfahren zur Stabilisierung biologischer Materialien mittels Trocknungsverfahren ohne Einfrieren
DE19716154A1 (de) * 1997-04-18 1998-10-22 Boehringer Mannheim Gmbh Stabile pharmazeutische Darreichungsform für Peptide, Proteine und Nukleinsäuren
MY120063A (en) † 1997-12-09 2005-08-30 Lilly Co Eli Stabilized teriparatide solutions
US6770623B1 (en) 1997-12-09 2004-08-03 Eli Lilly And Company Stabilized teriparatide solutions
SE9801495D0 (sv) * 1998-04-28 1998-04-28 Astra Ab Protein formulationa
WO2001032201A2 (en) * 1999-10-29 2001-05-10 Eli Lilly And Company A pharmaceutical composition having high cell membrane permeability
CN100518819C (zh) * 2000-06-30 2009-07-29 阿斯比奥制药株式会社 含有人甲状旁腺激素的药物成分及含有该成分的用于鼻内给药的药物组合物
US20050032698A1 (en) * 2003-07-14 2005-02-10 Nps Allelix Corp. Stabilized formulation of parathyroid hormone
USRE49444E1 (en) 2006-10-03 2023-03-07 Radius Health, Inc. Method of treating osteoporosis comprising administration of PTHrP analog
JPWO2012169435A1 (ja) 2011-06-07 2015-02-23 旭化成ファーマ株式会社 高純度ｐｔｈ含有凍結乾燥製剤およびその製造方法
EP3834824B1 (en) 2014-03-28 2025-10-22 Duke University Treatment of an estrogen receptor positive breast cancer using a selective estrogen receptor modulator
CN113750091B (zh) 2015-04-29 2025-03-11 雷迪厄斯制药公司 用于治疗癌症的方法
US10385008B2 (en) 2017-01-05 2019-08-20 Radius Pharmaceuticals, Inc. Polymorphic forms of RAD1901-2HCL
US10996208B2 (en) 2017-04-28 2021-05-04 Radius Health, Inc. Abaloparatide formulations and methods of testing, storing, modifying, and using same
AU2019297421B2 (en) 2018-07-04 2024-08-29 Radius Pharmaceuticals, Inc. Polymorphic forms of RAD 1901-2HCL
CN113348163B (zh) 2019-02-12 2024-10-08 雷迪厄斯制药公司 方法和化合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816568A (en) * 1986-05-16 1989-03-28 International Minerals & Chemical Corp. Stabilization of growth hormones
JP2739482B2 (ja) * 1988-08-11 1998-04-15 バイオ・チバ株式会社 安定なカルシトニン注射液の製造方法
JPH0341033A (ja) * 1989-07-07 1991-02-21 Kyowa Hakko Kogyo Co Ltd 安定なモチリン類含有製剤
WO1993011785A1 (fr) * 1991-12-09 1993-06-24 Asahi Kasei Kogyo Kabushiki Kaisha Composition a base d'hormone parathyroidienne stabilisee
DE4203040A1 (de) * 1992-02-04 1993-08-05 Boehringer Mannheim Gmbh Neue parathormonfragmente, deren herstellung und diese enthaltende arzneimittel

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011251988A (ja) * 2000-02-08 2011-12-15 Allergan Inc ボツリヌス毒素医薬組成物
WO2004075913A1 (ja) * 2003-02-28 2004-09-10 Chugai Seiyaku Kabushiki Kaisha タンパク質含有安定化製剤
JPWO2004075913A1 (ja) * 2003-02-28 2006-06-01 中外製薬株式会社 タンパク質含有安定化製剤
US8765124B2 (en) 2003-02-28 2014-07-01 Chugai Seiyaku Kabushiki Kaisha Stabilized preparation containing protein
US9968677B2 (en) 2003-02-28 2018-05-15 Chugai Seiyaku Kabushiki Kaisha Stabilized protein-containing formulations
JP2008542364A (ja) * 2005-06-03 2008-11-27 モガム バイオテクノロジー リサーチ インスティチュート 副甲状腺ホルモン、緩衝液、および安定剤を含んでなる安定化された副甲状腺ホルモン組成物
JP2015134795A (ja) * 2009-06-26 2015-07-27 ラボラトワール、フランセ、デュ、フラクショヌマン、エ、デ、ビオテクノロジＬａｂｏｒａｔｏｉｒｅ Ｆｒａｎｃａｉｓ Ｄｕ Ｆｒａｃｔｉｏｎｎｅｍｅｎｔ Ｅｔ Ｄｅｓ Ｂｉｏｔｅｃｈｎｏｌｏｇｉｅｓ 第ｖｉｉ因子組成物
JP2017081978A (ja) * 2009-06-26 2017-05-18 ラボラトワール、フランセ、デュ、フラクショヌマン、エ、デ、ビオテクノロジＬａｂｏｒａｔｏｉｒｅ Ｆｒａｎｃａｉｓ Ｄｕ Ｆｒａｃｔｉｏｎｎｅｍｅｎｔ Ｅｔ Ｄｅｓ Ｂｉｏｔｅｃｈｎｏｌｏｇｉｅｓ 第ｖｉｉ因子組成物
JP2017061424A (ja) * 2015-09-25 2017-03-30 ニプロ株式会社 液体組成物及び凍結乾燥製剤
JP2021088606A (ja) * 2017-09-22 2021-06-10 旭化成ファーマ株式会社 安定性に優れるテリパラチド含有液状医薬組成物
JP6947946B1 (ja) * 2020-05-11 2021-10-13 旭化成ファーマ株式会社 テリパラチド又はその塩を含有する安定な液状医薬製剤
WO2021229835A1 (ja) * 2020-05-11 2021-11-18 旭化成ファーマ株式会社 テリパラチド又はその塩を含有する安定な液状医薬製剤

Also Published As

Publication number Publication date
KR19990064322A (ko) 1999-07-26
SK47298A3 (en) 1998-11-04
TR199800690T1 (xx) 1998-06-22
HUP9900751A3 (en) 2000-07-28
HUP9900751A2 (hu) 1999-07-28
AU7294196A (en) 1997-05-07
NZ320237A (en) 1999-11-29
BR9610983A (pt) 1999-03-02
WO1997014429A1 (de) 1997-04-24
CZ108398A3 (cs) 1998-09-16
EP0855917A1 (de) 1998-08-05
CA2234724A1 (en) 1997-04-24
ZA968715B (en) 1998-04-16
DE19538687A1 (de) 1997-04-24

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