JPH11507026A5 - - Google Patents

Info

Publication number
JPH11507026A5
JPH11507026A5 JP1997500146A JP50014697A JPH11507026A5 JP H11507026 A5 JPH11507026 A5 JP H11507026A5 JP 1997500146 A JP1997500146 A JP 1997500146A JP 50014697 A JP50014697 A JP 50014697A JP H11507026 A5 JPH11507026 A5 JP H11507026A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997500146A
Other languages
English (en)
Japanese (ja)
Other versions
JPH11507026A (ja
JP4233113B2 (ja
Filing date
Publication date
Priority claimed from GBGB9512827.8A external-priority patent/GB9512827D0/en
Priority claimed from GBGB9513443.3A external-priority patent/GB9513443D0/en
Priority claimed from GBGB9525657.4A external-priority patent/GB9525657D0/en
Application filed filed Critical
Priority claimed from PCT/EP1996/002436 external-priority patent/WO1996040242A1/en
Publication of JPH11507026A publication Critical patent/JPH11507026A/ja
Publication of JPH11507026A5 publication Critical patent/JPH11507026A5/ja
Application granted granted Critical
Publication of JP4233113B2 publication Critical patent/JP4233113B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP50014697A 1995-06-07 1996-06-04 多糖類抗原−キャリア蛋白接合体および遊離キャリア蛋白を有してなるワクチン Expired - Lifetime JP4233113B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US47263995A 1995-06-07 1995-06-07
GB9512827.8 1995-06-23
GBGB9512827.8A GB9512827D0 (en) 1995-06-23 1995-06-23 Vaccines
GB9513443.3 1995-07-01
GBGB9513443.3A GB9513443D0 (en) 1995-07-01 1995-07-01 Vaccines
GB08/472,639 1995-12-15
GBGB9525657.4A GB9525657D0 (en) 1995-12-15 1995-12-15 Vaccines
GB9525657.4 1995-12-15
PCT/EP1996/002436 WO1996040242A1 (en) 1995-06-07 1996-06-04 Vaccine comprising a polysaccharide antigen-carrier protein conjugate and free carrier protein

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007061946A Division JP4653131B2 (ja) 1995-06-07 2007-03-12 多糖類抗原−キャリア蛋白接合体および遊離キャリア蛋白を有してなるワクチン

Publications (3)

Publication Number Publication Date
JPH11507026A JPH11507026A (ja) 1999-06-22
JPH11507026A5 true JPH11507026A5 (https=) 2004-07-08
JP4233113B2 JP4233113B2 (ja) 2009-03-04

Family

ID=27451300

Family Applications (2)

Application Number Title Priority Date Filing Date
JP50014697A Expired - Lifetime JP4233113B2 (ja) 1995-06-07 1996-06-04 多糖類抗原−キャリア蛋白接合体および遊離キャリア蛋白を有してなるワクチン
JP2007061946A Expired - Lifetime JP4653131B2 (ja) 1995-06-07 2007-03-12 多糖類抗原−キャリア蛋白接合体および遊離キャリア蛋白を有してなるワクチン

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2007061946A Expired - Lifetime JP4653131B2 (ja) 1995-06-07 2007-03-12 多糖類抗原−キャリア蛋白接合体および遊離キャリア蛋白を有してなるワクチン

Country Status (18)

Country Link
EP (2) EP1090642B8 (https=)
JP (2) JP4233113B2 (https=)
AT (2) ATE205724T1 (https=)
AU (1) AU695720B2 (https=)
BR (1) BR9608612A (https=)
CA (1) CA2221511C (https=)
CZ (1) CZ390297A3 (https=)
DE (2) DE69637597D1 (https=)
DK (1) DK1090642T3 (https=)
ES (2) ES2164251T5 (https=)
HU (1) HUP9802199A3 (https=)
IL (1) IL122431A0 (https=)
NO (1) NO975555L (https=)
NZ (1) NZ311000A (https=)
PT (1) PT1090642E (https=)
SI (1) SI1090642T1 (https=)
TR (1) TR199701547T1 (https=)
WO (1) WO1996040242A1 (https=)

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US6248334B1 (en) 1997-01-08 2001-06-19 Henry M. Jackson Foundation For The Advancement Of Military Medicine Process for preparing conjugate vaccines including free protein and the conjugate vaccines, immunogens, and immunogenic reagents produced by this process
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ES2275499T3 (es) 1999-03-19 2007-06-16 Glaxosmithkline Biologicals S.A. Vacuna contra streptococcus pneumoniae.
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OA12590A (en) 2001-01-23 2006-06-08 Aventis Pasteur Multivalent meningococcal polysaccharide-protein conjugate vaccine.
GB0115176D0 (en) 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
HUE031886T2 (en) 2002-10-11 2017-08-28 Glaxosmithkline Biologicals Sa Polypeptide vaccines for extensive protection against hypervirulent meningococcal lines
EP2395073B1 (en) 2002-11-01 2017-09-06 GlaxoSmithKline Biologicals S.A. Drying process
GB0227346D0 (en) 2002-11-22 2002-12-31 Chiron Spa 741
ES2461350T3 (es) 2003-01-30 2014-05-19 Novartis Ag Vacunas inyectables contra múltiples serogrupos de meningococos
PT2213661E (pt) 2003-09-26 2011-12-15 Exelixis Inc Moduladores de c-met e métodos de uso
GB0323103D0 (en) 2003-10-02 2003-11-05 Chiron Srl De-acetylated saccharides
CN103357002A (zh) 2003-10-02 2013-10-23 诺华疫苗和诊断有限公司 多种脑膜炎球菌血清群的液体疫苗
GB0406013D0 (en) 2004-03-17 2004-04-21 Chiron Srl Analysis of saccharide vaccines without interference
GB0409745D0 (en) 2004-04-30 2004-06-09 Chiron Srl Compositions including unconjugated carrier proteins
GB0500787D0 (en) 2005-01-14 2005-02-23 Chiron Srl Integration of meningococcal conjugate vaccination
ATE512670T1 (de) 2004-04-30 2011-07-15 Novartis Vaccines & Diagnostic Meningokokken-konjugat-impfung
GB0411387D0 (en) 2004-05-21 2004-06-23 Chiron Srl Analysis of saccharide length
GB0413868D0 (en) 2004-06-21 2004-07-21 Chiron Srl Dimensional anlaysis of saccharide conjugates
GB0428394D0 (en) * 2004-12-24 2005-02-02 Chiron Srl Saccharide conjugate vaccines
GB0502096D0 (en) 2005-02-01 2005-03-09 Chiron Srl Purification of streptococcal capsular polysaccharide
GB0502095D0 (en) 2005-02-01 2005-03-09 Chiron Srl Conjugation of streptococcal capsular saccharides
GB0505518D0 (en) 2005-03-17 2005-04-27 Chiron Srl Combination vaccines with whole cell pertussis antigen
JP2008536515A (ja) 2005-04-18 2008-09-11 ノバルティス ヴァクシンズ アンド ダイアグノスティクス, インコーポレイテッド ワクチンの調製のためのb型肝炎ウイルス表面抗原の発現
US8398983B2 (en) 2005-06-27 2013-03-19 Glaxosmithkline Biologicals, S.A. Immunogenic composition
NZ598367A (en) 2005-09-01 2013-10-25 Novartis Vaccines & Diagnostic Multiple vaccination including serogroup C meningococcus
GB0524066D0 (en) 2005-11-25 2006-01-04 Chiron Srl 741 ii
US10828361B2 (en) 2006-03-22 2020-11-10 Glaxosmithkline Biologicals Sa Regimens for immunisation with meningococcal conjugates
PL2004225T3 (pl) 2006-03-22 2012-09-28 Novartis Ag Schematy immunizacji koniugatami meningokokowymi
US8945582B2 (en) 2006-09-07 2015-02-03 Glaxosmithkline Biologicals S.A. Vaccine
GB0700136D0 (en) 2007-01-04 2007-02-14 Glaxosmithkline Biolog Sa Process for manufacturing vaccines
SI2349520T1 (sl) 2008-10-27 2016-08-31 Glaxosmithkline Biologicals S.A. Postopek čiščenja za ogljikohidrat iz Streptococcus skupine A
GB0822633D0 (en) 2008-12-11 2009-01-21 Novartis Ag Formulation
GB0822634D0 (en) 2008-12-11 2009-01-21 Novartis Ag Meningitis vaccines
US8974799B2 (en) 2009-09-30 2015-03-10 Novartis Ag Conjugation of Staphylococcus aureus type 5 and type 8 capsular polysaccharides
BR112012010223A2 (pt) 2009-10-30 2016-12-06 Novartis Ag purificação de staphylococcus aureus tipo 5 e tipo 8 sacarídeos capsulares
JP5781542B2 (ja) 2009-12-30 2015-09-24 ノバルティス アーゲー E.coliキャリアタンパク質に結合体化した多糖免疫原
CN102802662A (zh) 2010-03-18 2012-11-28 诺华有限公司 用于脑膜炎球菌血清组b的含佐剂疫苗
ES2744471T3 (es) 2010-09-04 2020-02-25 Glaxosmithkline Biologicals Sa Ensayos de anticuerpos bactericidas para evaluar la inmunogenia y la potencia de vacunas de sacárido capsular meningocócico
GB201101665D0 (en) 2011-01-31 2011-03-16 Novartis Ag Immunogenic compositions
WO2012085668A2 (en) 2010-12-24 2012-06-28 Novartis Ag Compounds
WO2012117377A1 (en) 2011-03-02 2012-09-07 Novartis Ag Combination vaccines with lower doses of antigen and/or adjuvant
GB201106340D0 (en) * 2011-04-14 2011-06-01 Isis Innovation Composition
EP2755683B1 (en) 2011-09-14 2019-04-03 GlaxoSmithKline Biologicals SA Methods for making saccharide-protein glycoconjugates
EP2776069A1 (en) 2011-11-07 2014-09-17 Novartis AG Carrier molecule comprising a spr0096 and a spr2021 antigen
EP2592137A1 (en) 2011-11-11 2013-05-15 Novartis AG Fermentation media free of animal-derived components for production of diphtheria toxoids suitable for human vaccine use
GB2495341B (en) 2011-11-11 2013-09-18 Novartis Ag Fermentation methods and their products
DE102011122891B4 (de) 2011-11-11 2014-12-24 Novartis Ag Fermentationsmedium, das frei von tierischen Bestandteilen ist, zur Herstellung von Diphtherie-Toxoiden zur Verwendung bei der Impfung von Menschen
DE102011118371B4 (de) 2011-11-11 2014-02-13 Novartis Ag Zur Impfung von Menschen geeignete Zusammensetzung, die ein Diphtherie-Toxoid umfasst, sowie Verfahren zu deren Herstellung
GB201121301D0 (en) 2011-12-12 2012-01-25 Novartis Ag Method
CN104159603A (zh) 2012-03-08 2014-11-19 诺华股份有限公司 带有tlr4激动剂的联合疫苗
WO2013174832A1 (en) 2012-05-22 2013-11-28 Novartis Ag Meningococcus serogroup x conjugate
US9526776B2 (en) 2012-09-06 2016-12-27 Glaxosmithkline Biologicals Sa Combination vaccines with serogroup B meningococcus and D/T/P
AR092897A1 (es) 2012-10-03 2015-05-06 Novartis Ag Composiciones inmunogenicas
US20150273036A1 (en) 2012-10-12 2015-10-01 Glaxosmithkline Biologicals Sa Non-cross-linked acellular pertussis antigens for use in combination vaccines
EP2934574A1 (en) 2012-12-18 2015-10-28 GlaxoSmithKline Biologicals SA Conjugates for protecting against diphtheria and/or tetanus
EP3792272A1 (en) 2013-01-04 2021-03-17 OBI Pharma, Inc. Vaccines with higher carbohydrate antigen density and novel saponin adjuvant
CN104174019A (zh) * 2014-09-23 2014-12-03 成都康华生物制品有限公司 四价脑膜炎球菌多糖载体蛋白结合疫苗
US9815886B2 (en) 2014-10-28 2017-11-14 Adma Biologics, Inc. Compositions and methods for the treatment of immunodeficiency
EP3034516A1 (en) 2014-12-19 2016-06-22 Novartis AG Purification of streptococcal capsular polysaccharide
US11612664B2 (en) 2016-04-05 2023-03-28 Gsk Vaccines S.R.L. Immunogenic compositions
CN109922828A (zh) 2016-10-20 2019-06-21 Km生物医药股份公司 使用具有降低了的分子量的PRP的Hib结合疫苗的制造方法
US10259865B2 (en) 2017-03-15 2019-04-16 Adma Biologics, Inc. Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection
EP3799884A1 (en) 2019-10-01 2021-04-07 GlaxoSmithKline Biologicals S.A. Immunogenic compositions
US11173199B2 (en) * 2019-11-13 2021-11-16 Alopexx Inc. Low contaminant compositions
WO2021174330A1 (en) * 2020-03-05 2021-09-10 Nuecology Biomedical Inc. Amphiphilic alginate-oleic acid macromolecules and process for preparation therof
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