JPH11500729A - 痛みの管理及び解毒のためのケタミンの点鼻及び点眼投与 - Google Patents
痛みの管理及び解毒のためのケタミンの点鼻及び点眼投与Info
- Publication number
- JPH11500729A JPH11500729A JP8525745A JP52574596A JPH11500729A JP H11500729 A JPH11500729 A JP H11500729A JP 8525745 A JP8525745 A JP 8525745A JP 52574596 A JP52574596 A JP 52574596A JP H11500729 A JPH11500729 A JP H11500729A
- Authority
- JP
- Japan
- Prior art keywords
- ketamine
- administration
- present
- detoxification
- nasal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Addiction (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Toxicology (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Description
Claims (1)
- 【特許請求の範囲】 1.解毒を促進し、物質中毒で苦しんでいると思われる患者における物質中毒を 治療する方法であって、解毒の促進又は薬物中毒の治療に有効な量のケタミンを 投与する方法。 2.ケタミンの投与量が約0.01〜約1mg/体重kgである請求の範囲第1 項に記載の方法。 3.ケタミンの投与量が約0.05〜約0.7mg/体重kgである請求の範囲第 2項に記載の方法。 4.薬物が、不快を抑制するのに有効な量のベンゾジアゼピンを更に含有する請 求の範囲第1項に記載の方法。 5.物質中毒が喫煙である請求の範囲第1項に記載の方法。 6.ケタミンが経粘膜経路によって投与される、請求の範囲第1項に記載の方法 。 7.上記経粘膜経路が、鼻、口咽頭、頬、舌下、直腸及び膣からなる群から選択 される請求の範囲第1項に記載の方法。 8.ケタミンが非経口投与経路によって投与される、請求の範囲第1項に記載の 方法。 9.上記非経口投与経路が、静脈及び筋肉からなる群から選択される請求の範囲 第8項に記載の方法。 10.ケタミンのエアゾール配合剤及び薬学的に許容される分散剤を含有する鼻吸 入器を含む患者の自己投与のための装置であって、解毒を促進し物質中毒を治療 するのに有効な量のケタミンを含むエアゾール配合剤の量を分散させるために計 量して提供することを特徴とする装置。 11.薬学的に許容されるガムにケタミンを含有する医薬組成物。 12.薬学的に許容されるキャンディーにケタミンを含有する医薬組成物。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1995/002418 WO1995022965A2 (en) | 1994-02-25 | 1995-02-24 | Nasal and ocular administration of ketamine to manage pain and for detoxification |
US08/477,365 US5679714A (en) | 1995-06-07 | 1995-06-07 | Administration of ketamine for detoxification and treatment of tobacco addiction |
US95/02418 | 1995-06-07 | ||
US08/477,365 | 1995-06-07 | ||
PCT/US1996/002047 WO1996025925A1 (en) | 1995-02-24 | 1996-02-14 | Nasal and ocular administration of ketamine to manage pain and for detoxification |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH11500729A true JPH11500729A (ja) | 1999-01-19 |
JP4173538B2 JP4173538B2 (ja) | 2008-10-29 |
Family
ID=26789531
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP52574596A Expired - Fee Related JP4173538B2 (ja) | 1995-02-24 | 1996-02-14 | 痛みの管理及び解毒のためのケタミンの点鼻及び点眼投与 |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0814790B1 (ja) |
JP (1) | JP4173538B2 (ja) |
AT (1) | ATE245024T1 (ja) |
AU (1) | AU733284B2 (ja) |
CA (1) | CA2213567C (ja) |
DE (1) | DE69629108T2 (ja) |
DK (1) | DK0814790T3 (ja) |
ES (1) | ES2205018T3 (ja) |
WO (1) | WO1996025925A1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2018517758A (ja) * | 2015-06-19 | 2018-07-05 | インプリミス・ファーマシューティカルズ・インコーポレイテッドImprimis Pharmaceuticals, Inc. | 麻酔用途のための医薬組成物 |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111643449A (zh) | 2013-03-15 | 2020-09-11 | 詹森药业有限公司 | S-盐酸氯胺酮的药物组合物 |
EP3725307A1 (en) | 2014-09-15 | 2020-10-21 | Janssen Pharmaceutica NV | Val66met (snp rs6265) genotype specific dosing regimens and methods for the treatment of depression |
US10555952B2 (en) | 2015-06-19 | 2020-02-11 | Melt Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for anesthesiological applications |
US10166240B2 (en) | 2015-06-19 | 2019-01-01 | Imprimis Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for anesthesiological applications |
US10179136B2 (en) | 2015-06-19 | 2019-01-15 | Imprimis Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for anesthesiological applications |
US10391102B2 (en) | 2015-06-19 | 2019-08-27 | Melt Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for anesthesiological applications |
US20200009081A1 (en) | 2017-09-13 | 2020-01-09 | Janssen Pharmaceutica N.V. | Delivery Of Esketamine For The Treatment Of Depression |
SG11202005896WA (en) | 2017-12-22 | 2020-07-29 | Janssen Pharmaceuticals Inc | Esketamine for the treatment of depression |
ES2907692T3 (es) * | 2017-12-29 | 2022-04-26 | Celon Pharma Sa | Composición de ketamina de polvo seco para su administración por vía pulmonar en la depresión resistente al tratamiento |
MX2021010683A (es) | 2019-03-05 | 2021-12-10 | Janssen Pharmaceuticals Inc | Esketamina para el tratamiento de la depresión. |
CN116942648A (zh) * | 2022-04-26 | 2023-10-27 | 宜昌人福药业有限责任公司 | 艾司氯胺酮液体制剂及其用途 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5288498A (en) * | 1985-05-01 | 1994-02-22 | University Of Utah Research Foundation | Compositions of oral nondissolvable matrixes for transmucosal administration of medicaments |
US5543434A (en) * | 1994-02-25 | 1996-08-06 | Weg; Stuart L. | Nasal administration of ketamine to manage pain |
-
1996
- 1996-02-14 EP EP96906452A patent/EP0814790B1/en not_active Expired - Lifetime
- 1996-02-14 CA CA2213567A patent/CA2213567C/en not_active Expired - Fee Related
- 1996-02-14 WO PCT/US1996/002047 patent/WO1996025925A1/en active IP Right Grant
- 1996-02-14 JP JP52574596A patent/JP4173538B2/ja not_active Expired - Fee Related
- 1996-02-14 DE DE69629108T patent/DE69629108T2/de not_active Expired - Lifetime
- 1996-02-14 ES ES96906452T patent/ES2205018T3/es not_active Expired - Lifetime
- 1996-02-14 DK DK96906452T patent/DK0814790T3/da active
- 1996-02-14 AU AU49827/96A patent/AU733284B2/en not_active Ceased
- 1996-02-14 AT AT96906452T patent/ATE245024T1/de active
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2018517758A (ja) * | 2015-06-19 | 2018-07-05 | インプリミス・ファーマシューティカルズ・インコーポレイテッドImprimis Pharmaceuticals, Inc. | 麻酔用途のための医薬組成物 |
Also Published As
Publication number | Publication date |
---|---|
WO1996025925A1 (en) | 1996-08-29 |
DE69629108T2 (de) | 2004-04-22 |
AU733284B2 (en) | 2001-05-10 |
CA2213567C (en) | 2010-01-26 |
EP0814790A1 (en) | 1998-01-07 |
DE69629108D1 (de) | 2003-08-21 |
DK0814790T3 (da) | 2003-11-10 |
ATE245024T1 (de) | 2003-08-15 |
AU4982796A (en) | 1996-09-11 |
ES2205018T3 (es) | 2004-05-01 |
CA2213567A1 (en) | 1996-08-29 |
JP4173538B2 (ja) | 2008-10-29 |
EP0814790B1 (en) | 2003-07-16 |
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