JPH11170A5 - - Google Patents
Info
- Publication number
- JPH11170A5 JPH11170A5 JP1997057503A JP5750397A JPH11170A5 JP H11170 A5 JPH11170 A5 JP H11170A5 JP 1997057503 A JP1997057503 A JP 1997057503A JP 5750397 A JP5750397 A JP 5750397A JP H11170 A5 JPH11170 A5 JP H11170A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- polypeptide
- acid sequence
- seq
- nucleotide sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1328596P | 1996-03-12 | 1996-03-12 | |
| US2871196P | 1996-10-17 | 1996-10-17 | |
| US3734197P | 1997-02-06 | 1997-02-06 | |
| US60/013285 | 1997-02-06 | ||
| US60/028711 | 1997-02-06 | ||
| US60/037341 | 1997-02-06 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH11170A JPH11170A (ja) | 1999-01-06 |
| JPH11170A5 true JPH11170A5 (cg-RX-API-DMAC7.html) | 2005-02-10 |
Family
ID=27359824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9057503A Pending JPH11170A (ja) | 1996-03-12 | 1997-03-12 | デスドメイン含有受容体 |
Country Status (3)
| Country | Link |
|---|---|
| US (3) | US6153402A (cg-RX-API-DMAC7.html) |
| JP (1) | JPH11170A (cg-RX-API-DMAC7.html) |
| WO (1) | WO1997033904A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030198640A1 (en) * | 1994-11-07 | 2003-10-23 | Human Genome Sciences, Inc. | Methods and compositions for treating inflammatory bowel diseases relating to human tumor necrosis factor-gamma-beta |
| US7597886B2 (en) | 1994-11-07 | 2009-10-06 | Human Genome Sciences, Inc. | Tumor necrosis factor-gamma |
| US7429646B1 (en) | 1995-06-05 | 2008-09-30 | Human Genome Sciences, Inc. | Antibodies to human tumor necrosis factor receptor-like 2 |
| US7888466B2 (en) | 1996-01-11 | 2011-02-15 | Human Genome Sciences, Inc. | Human G-protein chemokine receptor HSATU68 |
| WO1997033904A1 (en) | 1996-03-12 | 1997-09-18 | Human Genome Sciences, Inc. | Death domain containing receptors |
| US6713061B1 (en) | 1996-03-12 | 2004-03-30 | Human Genome Sciences, Inc. | Death domain containing receptors |
| US6635743B1 (en) | 1996-03-22 | 2003-10-21 | Human Genome Sciences, Inc. | Apoptosis inducing molecule II and methods of use |
| US7964190B2 (en) | 1996-03-22 | 2011-06-21 | Human Genome Sciences, Inc. | Methods and compositions for decreasing T-cell activity |
| US20020165157A1 (en) * | 1996-04-01 | 2002-11-07 | Genentech, Inc. | Apo-2LI and Apo-3 polypeptides |
| EP0904366A1 (en) * | 1996-04-01 | 1999-03-31 | Genentech, Inc. | Apo-2li and apo-3 apoptosis polypeptides |
| US6462176B1 (en) * | 1996-09-23 | 2002-10-08 | Genentech, Inc. | Apo-3 polypeptide |
| EP0960196A4 (en) * | 1996-10-04 | 2002-10-29 | Immunex Corp | CELL DEATH CAUSING RECEPTOR |
| US6297022B1 (en) | 1997-10-08 | 2001-10-02 | Smithkline Beecham Corporation | Method of identifying agonists and antagonists for tumor necrosis related receptor TR1 |
| WO1999041374A2 (en) * | 1998-02-17 | 1999-08-19 | Incyte Pharmaceuticals, Inc. | Human short-chain tnf-receptor family protein |
| US20030078211A1 (en) * | 1998-06-24 | 2003-04-24 | Merck & Co., Inc. | Compositions and methods for inhibiting bone resorption |
| JP2002537769A (ja) | 1999-02-26 | 2002-11-12 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | ヒトエンドカインαおよび使用方法 |
| AU4478200A (en) * | 1999-04-22 | 2000-11-10 | Human Genome Sciences, Inc. | Death domain containing receptors |
| AU6934600A (en) * | 1999-08-27 | 2001-03-26 | Board Of Regents, The University Of Texas System | Cd40 ligand and cd40 agonist compositions and methods of use |
| AU784504B2 (en) * | 1999-11-19 | 2006-04-13 | Thomas V. Tittle | TR3-specific binding agents and methods for their use |
| US6994976B1 (en) | 1999-11-19 | 2006-02-07 | Tittle Thomas V | Tr3-specific binding agents and methods for their use |
| EP1983055A1 (en) | 2000-04-12 | 2008-10-22 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| WO2001096528A2 (en) | 2000-06-15 | 2001-12-20 | Human Genome Sciences, Inc. | Human tumor necrosis factor delta and epsilon |
| WO2002002641A1 (en) | 2000-06-16 | 2002-01-10 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to blys |
| CA2426765C (en) | 2000-10-24 | 2012-06-05 | Shunichi Shiozawa | Genomes participating in rheumatoid arthritis, method of the diagnosis thereof, method of evaluating the onset possibility thereof, diagnostic kit for detecting them and therapeutic method and remedies for rheumatoid arthritis |
| US6965023B2 (en) * | 2000-11-17 | 2005-11-15 | The Burnham Institute | Death domain proteins |
| EP2261250B1 (en) | 2001-12-21 | 2015-07-01 | Human Genome Sciences, Inc. | GCSF-Albumin fusion proteins |
| WO2005018571A2 (en) * | 2003-08-20 | 2005-03-03 | University Of Miami | Compositions and methods for treating inflammatory lung disease |
| US20070128184A1 (en) | 2005-08-30 | 2007-06-07 | Eckhard Podack | Immunomodulating tumor necrosis factor receptor 25 (TNFR25) agonists, antagonists and immunotoxins |
| JP5905184B2 (ja) | 2005-10-13 | 2016-04-20 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッドHuman Genome Sciences, Inc. | 自己抗体陽性疾患を有する患者の処置に使用するための方法および組成物 |
| US9896511B2 (en) | 2007-01-10 | 2018-02-20 | The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services | Antibodies that bind to TL1A and methods of treating inflammatory or autoimmune disease comprising administering such antibodies |
| MX2011003039A (es) | 2008-09-26 | 2011-08-15 | Tocagen Inc | Vectores de terapia genica y citosina deaminasas. |
| US9499627B2 (en) | 2009-08-03 | 2016-11-22 | University Of Miami | Method for in vivo expansion of T regulatory cells |
| CN103874707B (zh) | 2010-11-19 | 2017-04-19 | 卫材R&D管理有限公司 | 中和抗‑ccl20抗体 |
| EP2681237A1 (en) | 2011-03-01 | 2014-01-08 | Novo Nordisk A/S | Antagonistic dr3 ligands |
| CA2836898A1 (en) | 2011-05-20 | 2012-11-29 | Government Of The United States, As Represented By The Secretary, Department Of Health And Human Services | Blockade of tl1a-dr3 interactions to ameliorate t cell mediated disease pathology and antibodies thereof |
| EP2909324B1 (en) | 2012-10-25 | 2020-02-26 | Tocagen Inc. | Retroviral vector with mini-promoter cassette |
| US20140193410A1 (en) | 2013-01-09 | 2014-07-10 | University Of Miami | Compositions and Methods for the Regulation of T Regulatory Cells Using TL1A-Ig Fusion Protein |
| DK2970473T3 (da) | 2013-03-14 | 2017-11-27 | Bristol Myers Squibb Co | Kombination af dr5-agonist og anti-pd-1-antagonist og fremgangsmåder til anvendelse heraf |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| DE3382137D1 (de) * | 1982-07-30 | 1991-02-28 | Bernard Francois Mach | Dns-sequenzenkodieren fuer den dr-beta-kettenlocus des menschlichen lymphocytantigenkomplexes und polypeptiden, diagnostische typierungsverfahren und produkte die darauf bezug haben. |
| US5120525A (en) | 1988-03-29 | 1992-06-09 | Immunomedics, Inc. | Radiolabeled antibody cytotoxic therapy of cancer |
| US5349052A (en) | 1988-10-20 | 1994-09-20 | Royal Free Hospital School Of Medicine | Process for fractionating polyethylene glycol (PEG)-protein adducts and an adduct for PEG and granulocyte-macrophage colony stimulating factor |
| WO1990006952A1 (fr) | 1988-12-22 | 1990-06-28 | Kirin-Amgen, Inc. | Facteur de stimulation de colonies de granulocytes modifies chimiquement |
| IL106271A (en) * | 1992-09-03 | 2008-03-20 | Yeda Res & Dev | Ligand to TNF 75P receptor and its preparation |
| US5395760A (en) * | 1989-09-05 | 1995-03-07 | Immunex Corporation | DNA encoding tumor necrosis factor-α and -β receptors |
| US5464938A (en) * | 1990-04-09 | 1995-11-07 | Immunex Corporation | Isolated viral protein TNF antagonists |
| US5656272A (en) | 1991-03-18 | 1997-08-12 | New York University Medical Center | Methods of treating TNF-α-mediated Crohn's disease using chimeric anti-TNF antibodies |
| CA2064331C (en) | 1991-03-28 | 2003-02-18 | Marvin L. Bayne | Vascular endothelial cell growth factor c subunit |
| IL99120A0 (en) | 1991-08-07 | 1992-07-15 | Yeda Res & Dev | Multimers of the soluble forms of tnf receptors,their preparation and pharmaceutical compositions containing them |
| WO1994009137A1 (en) * | 1992-10-15 | 1994-04-28 | Genentech, Inc. | Antibodies against type 2 tumor necrosis factor receptor |
| ATE397665T1 (de) * | 1992-12-04 | 2008-06-15 | Biogen Idec Inc | Lymphotoxin-beta, lymphotoxin-beta komplexe, pharmazeutische zubereitungen und therapeutische verwendungen davon |
| GB9317618D0 (en) | 1993-08-24 | 1993-10-06 | Royal Free Hosp School Med | Polymer modifications |
| JPH09503672A (ja) | 1993-10-14 | 1997-04-15 | イミュネックス・コーポレーション | Fas拮抗剤とその利用 |
| US5643575A (en) | 1993-10-27 | 1997-07-01 | Enzon, Inc. | Non-antigenic branched polymer conjugates |
| US6608182B1 (en) | 1994-03-08 | 2003-08-19 | Human Genome Sciences, Inc. | Human vascular endothelial growth factor 2 |
| US6599719B2 (en) | 1994-11-07 | 2003-07-29 | Human Genome Sciences, Inc. | Nucleic acid molecules encoding tumor necrosis factor-gamma-alpha |
| KR100507431B1 (ko) | 1994-11-07 | 2005-12-21 | 휴먼 게놈 사이언시즈, 인코포레이티드 | 종양괴사인자-γ |
| US5928939A (en) | 1995-03-01 | 1999-07-27 | Ludwig Institute For Cancer Research | Vascular endothelial growth factor-b and dna coding therefor |
| EP2017337A1 (en) | 1995-04-27 | 2009-01-21 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptors |
| WO1997033904A1 (en) | 1996-03-12 | 1997-09-18 | Human Genome Sciences, Inc. | Death domain containing receptors |
| WO1997033899A1 (en) | 1996-03-14 | 1997-09-18 | Human Genome Sciences, Inc. | Apoptosis inducing molecule i |
| WO1997034911A1 (en) | 1996-03-22 | 1997-09-25 | Human Genome Sciences, Inc. | Apoptosis inducing molecule ii |
| EP0904366A1 (en) * | 1996-04-01 | 1999-03-31 | Genentech, Inc. | Apo-2li and apo-3 apoptosis polypeptides |
| WO1998002543A1 (fr) | 1996-07-15 | 1998-01-22 | Chugai Research Institute For Molecular Medicine, Inc. | Nouveaux facteurs analogues au vegf |
| CA2260754C (en) | 1996-07-15 | 2012-01-24 | Chugai Research Institute For Molecular Medicine, Inc. | Novel vegf-like factor |
| ATE397660T1 (de) | 1996-08-16 | 2008-06-15 | Schering Corp | Zelloberflächen-antigen aus säugetieren und verwandte reagenzien |
| EP0961831B1 (en) | 1996-08-16 | 2008-10-29 | Human Genome Sciences, Inc. | Human endokine alpha |
| DE69734359T2 (de) | 1996-08-23 | 2006-07-06 | Ludwig Institute For Cancer Research | Rekombinanter vaskulärer endothelzellen wachstumsfaktor d (vegf-d) |
| EP0960196A4 (en) * | 1996-10-04 | 2002-10-29 | Immunex Corp | CELL DEATH CAUSING RECEPTOR |
| AU731553B2 (en) | 1996-10-25 | 2001-04-05 | Human Genome Sciences, Inc. | Neutrokine alpha |
| US6261801B1 (en) | 1997-01-14 | 2001-07-17 | Human Genome Sceineces, Inc. | Nucleic acids encoding tumor necrosis factor receptor 5 |
| CN1247567A (zh) | 1997-01-14 | 2000-03-15 | 人体基因组科学有限公司 | 肿瘤坏死因子受体6α和6β |
| WO1998032856A1 (en) | 1997-01-28 | 1998-07-30 | Human Genome Sciences, Inc. | Death domain containing receptor 4 (dr4: death receptor 4), member of the tnf-receptor superfamily and binding to trail (ap02-l) |
| ATE200030T1 (de) | 1997-01-29 | 2001-04-15 | Polymasc Pharmaceuticals Plc | Pegylationsverfahren |
| CN1624128A (zh) | 1997-03-17 | 2005-06-08 | 人类基因组科学公司 | 包含死亡结构域的受体-5 |
| WO1998049305A1 (en) | 1997-05-01 | 1998-11-05 | Amgen Inc. | Chimeric opg polypeptides |
| WO1998056892A1 (en) | 1997-06-11 | 1998-12-17 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptor tr9 |
-
1996
- 1996-10-17 WO PCT/US1996/016849 patent/WO1997033904A1/en not_active Ceased
-
1997
- 1997-03-11 US US08/815,469 patent/US6153402A/en not_active Expired - Fee Related
- 1997-03-12 JP JP9057503A patent/JPH11170A/ja active Pending
-
1999
- 1999-05-19 US US09/314,889 patent/US6951735B2/en not_active Expired - Lifetime
- 1999-06-16 US US09/333,966 patent/US6759513B2/en not_active Expired - Lifetime
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