JPH10506908A - 生物活性ケイ質ガラスの新規な使用及び生物活性ケイ質ガラスを含有する新規な組成物 - Google Patents
生物活性ケイ質ガラスの新規な使用及び生物活性ケイ質ガラスを含有する新規な組成物Info
- Publication number
- JPH10506908A JPH10506908A JP8512350A JP51235096A JPH10506908A JP H10506908 A JPH10506908 A JP H10506908A JP 8512350 A JP8512350 A JP 8512350A JP 51235096 A JP51235096 A JP 51235096A JP H10506908 A JPH10506908 A JP H10506908A
- Authority
- JP
- Japan
- Prior art keywords
- glass
- formulation
- dentin
- bioactive
- silica
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
- A61K6/802—Preparations for artificial teeth, for filling teeth or for capping teeth comprising ceramics
- A61K6/816—Preparations for artificial teeth, for filling teeth or for capping teeth comprising ceramics comprising titanium oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/15—Compositions characterised by their physical properties
- A61K6/17—Particle size
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/30—Compositions for temporarily or permanently fixing teeth or palates, e.g. primers for dental adhesives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/50—Preparations specially adapted for dental root treatment
- A61K6/54—Filling; Sealing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
- A61K6/802—Preparations for artificial teeth, for filling teeth or for capping teeth comprising ceramics
- A61K6/807—Preparations for artificial teeth, for filling teeth or for capping teeth comprising ceramics comprising magnesium oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
- A61K6/831—Preparations for artificial teeth, for filling teeth or for capping teeth comprising non-metallic elements or compounds thereof, e.g. carbon
- A61K6/836—Glass
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Plastic & Reconstructive Surgery (AREA)
- Chemical & Material Sciences (AREA)
- Ceramic Engineering (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Glass Compositions (AREA)
- Dental Preparations (AREA)
- Materials For Medical Uses (AREA)
Abstract
Description
Claims (1)
- 【特許請求の範囲】 1.ガラスを含有する生物活性シリカの新規な使用であって、前記ガラスが歯 髄の刺激を減少及び/または歯の構造を強化するのに有用な製剤の製造に用いら れることを特徴とする、前記使用。 2.ガラスを含有する生物活性シリカが、粉末、生理的に適当な液体とのペー スト、懸濁液もしくは溶液の形で用いられるか、または生理的に適当な賦形剤と 結合していることを特徴とする、請求項1に記載の使用。 3.ガラスを含有する生物活性シリカがカルシウム及びリン酸イオンを含有し ているか、または製剤にカルシウム及びリン酸塩を供給する源が加えられている ことを特徴とする、請求項1または2に記載の使用。 4.歯髄の刺激を減少及び/または歯の構造を強化する医薬製剤であって、ガ ラスを含有する生物活性シリカを含むガラス相が − 生理的に適当な液体と混合されて、ペースト、懸濁液もしくは溶液を形成す るか、または − ガラス相とぞうげ質との間の化学的な相互作用を維持するのに十分に湿って いて、シリカのぞうげ質組織中への転移を可能とさせる製剤を産する、生理的に 適当な結合剤、たとえば、フィブリノーゲンもしくはキチンと混合されているこ とを特徴とする、前記医薬製剤。 5.カルシウム及びリン酸源を含むことを特徴とする、請求項4に記載の製剤 。 6.前記製剤が標的組織中の結晶の成長を促進する薬剤を含むことを特徴とす る、請求項4または5に記載の製剤。 7.ガラス相が、 − Si−酸化物もしくはSi−水酸化物、たとえばシリカゲルだけであるか、また は − Si−酸化物もしくはSi−水酸化物に追加して、Na,K,Ca,Mg,B,Ti,Al ,P,NもしくはFの1つもしくはそれよりも多い元素を含むか、または、 − Si−OH−基を含有する溶液であることを特徴とする、請求項4,5または6 に記載の製剤。 8.ガラス相の組成が、 SiO2またはSi−ゲル 1−100 % CaO 0−40% P2O5 0−60% Na2O 0−45% K2O 0−45% MgO 0−40% であることを特徴とする、請求項7に記載の製剤。 9.ガラス相の組成が、SiO253%、CaO 20%、P2O54%及び Na2O 23%である ことを特徴とする、請求項7に記載の製剤。 10.ガラス相の組成が、SiO245%、CaO 22%、P2O57%、Na2O 24%及びB2O32 %であることを特徴とする、請求項7に記載の製剤。 11.製剤がセラミック粉末を含むことを特徴とする、前記請求項のいずれか1 項に記載の製剤。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI944672 | 1994-10-06 | ||
FI944672A FI104881B (fi) | 1994-10-06 | 1994-10-06 | Uusien bioaktiivista piipitoista lasia sisältävien koostumusten valmistusmenetelmä |
PCT/FI1995/000539 WO1996010985A1 (en) | 1994-10-06 | 1995-10-02 | New use of bioactive silicious glass and new compositions containing bioactive silicious glass |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH10506908A true JPH10506908A (ja) | 1998-07-07 |
JP3524102B2 JP3524102B2 (ja) | 2004-05-10 |
Family
ID=8541520
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP51235096A Expired - Lifetime JP3524102B2 (ja) | 1994-10-06 | 1995-10-02 | 生物活性ケイ質ガラスの新規な使用及び生物活性ケイ質ガラスを含有する新規な組成物 |
Country Status (16)
Country | Link |
---|---|
US (1) | US5891233A (ja) |
EP (1) | EP0804136B1 (ja) |
JP (1) | JP3524102B2 (ja) |
KR (1) | KR100381308B1 (ja) |
AT (1) | ATE238753T1 (ja) |
AU (1) | AU702580B2 (ja) |
CA (1) | CA2200218C (ja) |
CZ (1) | CZ292434B6 (ja) |
DE (1) | DE69530608T2 (ja) |
ES (1) | ES2198444T3 (ja) |
FI (1) | FI104881B (ja) |
HU (1) | HU222368B1 (ja) |
NO (1) | NO310094B1 (ja) |
PL (1) | PL319483A1 (ja) |
RU (1) | RU2152778C1 (ja) |
WO (1) | WO1996010985A1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2011518810A (ja) * | 2008-04-24 | 2011-06-30 | ガバ・インターナショナル・ホールディング・アクチェンゲゼルシャフト | 溶解スズおよびフッ化物イオンを含有する口腔ケア組成物 |
WO2018003419A1 (ja) * | 2016-06-30 | 2018-01-04 | 株式会社ジーシー | 歯科用処置材、及び歯科用処置材キット |
Families Citing this family (66)
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PL328149A1 (en) | 1996-01-29 | 1999-01-18 | Univ Maryland | Bioactive glass compositions and therapeutic methods employing bioactive glass |
US5735942A (en) | 1996-02-07 | 1998-04-07 | Usbiomaterials Corporation | Compositions containing bioactive glass and their use in treating tooth hypersensitivity |
IN191261B (ja) * | 1997-09-18 | 2003-10-18 | Univ Maryland | |
US6190643B1 (en) | 1999-03-02 | 2001-02-20 | Patricia Stoor | Method for reducing the viability of detrimental oral microorganisms in an individual, and for prevention and/or treatment of diseases caused by such microorganisms; and whitening and/or cleaning of an individual's teeth |
US7323160B2 (en) * | 1999-08-14 | 2008-01-29 | Teldent Ltd. | Method of treating a patient's teeth using fluoride releasing glass composition |
GB9919283D0 (en) * | 1999-08-14 | 1999-10-20 | Algar Brian | A glass composition |
US6495168B2 (en) | 2000-03-24 | 2002-12-17 | Ustherapeutics, Llc | Nutritional supplements formulated from bioactive materials |
PL363113A1 (en) | 2000-03-27 | 2004-11-15 | Schott Glas | New cosmetic, personal care, cleaning agent, and nutritional supplement compositions comprising bioactive glass and methods of making and using the same |
US6375935B1 (en) | 2000-04-28 | 2002-04-23 | Brent R. Constantz | Calcium phosphate cements prepared from silicate solutions |
US7820191B2 (en) | 2000-04-28 | 2010-10-26 | Skeletal Kinetics, Llc | Calcium phosphate cements prepared from silicate solutions |
US6787584B2 (en) * | 2000-08-11 | 2004-09-07 | Pentron Corporation | Dental/medical compositions comprising degradable polymers and methods of manufacture thereof |
US20070059257A1 (en) * | 2000-08-18 | 2007-03-15 | Block Drug Company, Inc. | Dentinal composition for hypersensitive teeth |
DE10111449A1 (de) * | 2001-03-09 | 2002-09-26 | Schott Glas | Verwendung von bioaktivem Glas in Zahnfüllmaterial |
US7597900B2 (en) * | 2001-03-27 | 2009-10-06 | Schott Ag | Tissue abrasives |
EP1392611B1 (en) * | 2001-03-30 | 2005-05-18 | King's College London | Use of bioactive glass for cutting bioactive glasses |
US6416745B1 (en) | 2001-05-03 | 2002-07-09 | Block Drug Company, Inc. | Dental composition for treating hypersensitive teeth |
US7211136B2 (en) * | 2001-10-24 | 2007-05-01 | Pentron Clinical Technologies, Llc | Dental filling material |
US7204875B2 (en) * | 2001-10-24 | 2007-04-17 | Pentron Clinical Technologies, Llc | Dental filling material |
US7303817B2 (en) * | 2001-10-24 | 2007-12-04 | Weitao Jia | Dental filling material |
US7204874B2 (en) * | 2001-10-24 | 2007-04-17 | Pentron Clinical Technologies, Llc | Root canal filling material |
US7750063B2 (en) | 2001-10-24 | 2010-07-06 | Pentron Clinical Technologies, Llc | Dental filling material |
US20030167967A1 (en) * | 2002-03-01 | 2003-09-11 | Timo Narhi | Glass ionomers for enhancing mineralization of hard tissue |
US8128911B2 (en) | 2002-05-10 | 2012-03-06 | Colgate-Palmolive Company | Antibacterial dentifrice exhibiting enhanced antiplaque and breath freshening properties |
US8168208B1 (en) * | 2002-06-03 | 2012-05-01 | Ahmed El-Ghannam | Silica-calcium phosphate bioactive composite for improved synthetic graft resorbability and tissue regeneration |
EP1599182A4 (en) * | 2003-02-21 | 2008-08-20 | Rhodia | ORAL HYGIENE AGENT ULTRA-SOFT ANTI-SENSITIVITY, ANTI-CARIES, ANTI-TASKS, ANTI-PLAQUE |
FI20030780A0 (fi) * | 2003-05-23 | 2003-05-23 | Bioxid Oy | Prepreg ja sen käyttö |
US20040250730A1 (en) * | 2003-06-12 | 2004-12-16 | David Delaney | Calcium phosphate cements prepared from silicate-phosphate solutions |
US7306786B2 (en) * | 2003-07-28 | 2007-12-11 | Skeletal Kinetics, Llc | Calcium phosphate cements comprising a water-soluble contrast agent |
KR20070054147A (ko) * | 2004-07-02 | 2007-05-28 | 디스커스 덴탈 임프레션스 인코포레이티드 | 민감성을 경감시키는 치과용 조성물 |
AU2005306869B2 (en) | 2004-11-16 | 2011-11-10 | 3M Innovative Properties Company | Dental fillers including a phosphoruscontaining surface treatment |
WO2006055328A1 (en) * | 2004-11-16 | 2006-05-26 | 3M Innovative Properties Company | Dental fillers, methods, compositions including a caseinate |
CA2588103A1 (en) | 2004-11-16 | 2006-05-26 | 3M Innovative Properties Company | Dental compositions with calcium phosphorus releasing glass |
DE602005025682D1 (de) * | 2004-11-16 | 2011-02-10 | 3M Innovative Properties Co | Dentalfüllstoffe und zusammensetzungen mit phosphatsalzen |
US20070258916A1 (en) * | 2006-04-14 | 2007-11-08 | Oregon Health & Science University | Oral compositions for treating tooth hypersensitivity |
GB0616716D0 (en) * | 2006-08-23 | 2006-10-04 | Novathera Ltd | Composite material |
US20100260849A1 (en) * | 2007-12-13 | 2010-10-14 | Rusin Richard P | Remineralizing compositions and methods |
GB0801836D0 (en) * | 2008-01-31 | 2008-03-05 | Glaxo Group Ltd | Novel composition |
US20090197221A1 (en) * | 2008-02-04 | 2009-08-06 | Marshall Jr Grayson W | Dental bonding compositions and methods useful in inhibition of microleakage in resin-bonded dentin |
US8211407B2 (en) | 2008-11-25 | 2012-07-03 | The Procter & Gamble Company | Method of making oral care compositions with fused silica slurries |
US8551457B2 (en) | 2008-11-25 | 2013-10-08 | The Procter & Gamble Company | Oral care compositions comprising spherical fused silica |
US8790707B2 (en) * | 2008-12-11 | 2014-07-29 | 3M Innovative Properties Company | Surface-treated calcium phosphate particles suitable for oral care and dental compositions |
FI20095084A0 (fi) | 2009-01-30 | 2009-01-30 | Pekka Vallittu | Komposiitti ja sen käyttö |
TWI391148B (zh) | 2009-04-01 | 2013-04-01 | Colgate Palmolive Co | 含有生物可接受性及生物活性之玻璃的非水性牙膏組成物及其使用與製造之方法 |
TWI469795B (zh) | 2009-04-01 | 2015-01-21 | Colgate Palmolive Co | 防止過敏和促進再礦化之雙作用牙劑組成物 |
US8632754B2 (en) | 2009-08-03 | 2014-01-21 | Mcneil-Ppc, Inc. | Tooth sensitivity treatment compositions |
US8603442B2 (en) | 2009-08-03 | 2013-12-10 | Mcneil-Ppc, Inc. | Tooth sensitivity treatment compositions |
US9060947B2 (en) | 2009-08-03 | 2015-06-23 | Mcneil-Ppc, Inc. | Tooth sensitivity treatment compositions |
US8715625B1 (en) | 2010-05-10 | 2014-05-06 | The Clorox Company | Natural oral care compositions |
EP3785739A1 (en) * | 2010-06-02 | 2021-03-03 | Cap Biomaterials, LLC | Glassy calcium phosphate particulates, coatings and related bone graft materials |
US8722080B2 (en) | 2011-03-11 | 2014-05-13 | Gary D. Hack | Treatment and prevention of dental pathology in humans and non-human animals |
GB201113754D0 (en) | 2011-08-09 | 2011-09-21 | Glaxo Group Ltd | Composition |
WO2013034421A2 (en) | 2011-09-08 | 2013-03-14 | Unilever N.V. | Tooth remineralizing dentifrice |
BR112014024873B1 (pt) | 2012-04-05 | 2019-12-03 | Unilever Nv | composição para tratamento oral não aquosa e processo de preparo da composição |
EP2906182B1 (en) | 2012-10-12 | 2016-11-30 | Unilever N.V. | Oral care composition |
WO2014071284A2 (en) | 2012-11-05 | 2014-05-08 | The Procter & Gamble Company | Heat treated precipitated silica |
US10111814B2 (en) * | 2013-04-19 | 2018-10-30 | National Taipei University Of Technology | Desensitizing toothpaste |
US9168114B2 (en) | 2013-10-17 | 2015-10-27 | B & D Dental Corp. | Method of making a dental prosthesis |
US20190365615A1 (en) | 2016-06-20 | 2019-12-05 | Helicon Medical, S.L. | Composition of materials for tooth remineralisation |
GB201621685D0 (en) | 2016-12-20 | 2017-02-01 | Glaxosmithkline Consumer Healthcare (Uk) Ip Ltd | Novel composition |
EP3668604B1 (en) | 2017-08-18 | 2021-10-13 | Unilever Global IP Limited | Oral care composition |
EP3668477A1 (en) | 2017-08-18 | 2020-06-24 | Unilever N.V. | Oral care composition |
GB201721001D0 (en) * | 2017-12-15 | 2018-01-31 | Glaxosmithkline Consumer Healthcare (Uk) Ip Ltd | Novel Composition |
US11752072B2 (en) | 2019-03-11 | 2023-09-12 | University Of Utah Research Foundation | Quick set cements for dental pulp capping and related methods of use |
KR102293306B1 (ko) * | 2019-11-26 | 2021-08-25 | 단국대학교 천안캠퍼스 산학협력단 | 이온방출형 생활성 글라스 나노파티클을 포함하는 항염증용 약학적 조성물 |
GB202214700D0 (en) | 2022-10-06 | 2022-11-23 | GlaxoSmithKline Consumer Healthcare UK IP Ltd | Dentifrice composition |
CN117303736B (zh) * | 2023-09-18 | 2024-06-18 | 哈尔滨理工大学 | 一种含有机硅组份的生物活性玻璃及其制备方法 |
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US5735942A (en) * | 1996-02-07 | 1998-04-07 | Usbiomaterials Corporation | Compositions containing bioactive glass and their use in treating tooth hypersensitivity |
-
1994
- 1994-10-06 FI FI944672A patent/FI104881B/fi not_active IP Right Cessation
-
1995
- 1995-10-02 EP EP95934137A patent/EP0804136B1/en not_active Expired - Lifetime
- 1995-10-02 WO PCT/FI1995/000539 patent/WO1996010985A1/en active IP Right Grant
- 1995-10-02 CA CA002200218A patent/CA2200218C/en not_active Expired - Lifetime
- 1995-10-02 ES ES95934137T patent/ES2198444T3/es not_active Expired - Lifetime
- 1995-10-02 KR KR1019970702117A patent/KR100381308B1/ko not_active IP Right Cessation
- 1995-10-02 CZ CZ1997850A patent/CZ292434B6/cs not_active IP Right Cessation
- 1995-10-02 RU RU97108274/14A patent/RU2152778C1/ru active
- 1995-10-02 HU HU9702277A patent/HU222368B1/hu active IP Right Grant
- 1995-10-02 US US08/809,867 patent/US5891233A/en not_active Expired - Lifetime
- 1995-10-02 JP JP51235096A patent/JP3524102B2/ja not_active Expired - Lifetime
- 1995-10-02 DE DE69530608T patent/DE69530608T2/de not_active Expired - Lifetime
- 1995-10-02 PL PL95319483A patent/PL319483A1/xx unknown
- 1995-10-02 AT AT95934137T patent/ATE238753T1/de active
- 1995-10-02 AU AU36537/95A patent/AU702580B2/en not_active Expired
-
1997
- 1997-04-04 NO NO19971563A patent/NO310094B1/no not_active IP Right Cessation
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2011518810A (ja) * | 2008-04-24 | 2011-06-30 | ガバ・インターナショナル・ホールディング・アクチェンゲゼルシャフト | 溶解スズおよびフッ化物イオンを含有する口腔ケア組成物 |
WO2018003419A1 (ja) * | 2016-06-30 | 2018-01-04 | 株式会社ジーシー | 歯科用処置材、及び歯科用処置材キット |
US10918577B2 (en) | 2016-06-30 | 2021-02-16 | Gc Corporation | Dental treatment material and dental treatment material kit |
Also Published As
Publication number | Publication date |
---|---|
CZ292434B6 (cs) | 2003-09-17 |
CA2200218A1 (en) | 1996-04-18 |
KR100381308B1 (ko) | 2003-09-26 |
DE69530608T2 (de) | 2004-02-26 |
ATE238753T1 (de) | 2003-05-15 |
KR970705969A (ko) | 1997-11-03 |
PL319483A1 (en) | 1997-08-04 |
DE69530608D1 (de) | 2003-06-05 |
FI104881B (fi) | 2000-04-28 |
HUT77863A (hu) | 1998-08-28 |
NO310094B1 (no) | 2001-05-21 |
FI944672A0 (fi) | 1994-10-06 |
JP3524102B2 (ja) | 2004-05-10 |
NO971563D0 (no) | 1997-04-04 |
HU222368B1 (hu) | 2003-06-28 |
ES2198444T3 (es) | 2004-02-01 |
CA2200218C (en) | 2003-07-22 |
AU702580B2 (en) | 1999-02-25 |
RU2152778C1 (ru) | 2000-07-20 |
FI944672A (fi) | 1996-04-07 |
EP0804136B1 (en) | 2003-05-02 |
AU3653795A (en) | 1996-05-02 |
WO1996010985A1 (en) | 1996-04-18 |
US5891233A (en) | 1999-04-06 |
NO971563L (no) | 1997-04-04 |
EP0804136A1 (en) | 1997-11-05 |
CZ85097A3 (en) | 1997-09-17 |
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