JPH10504916A - Led点走査システム - Google Patents
Led点走査システムInfo
- Publication number
- JPH10504916A JPH10504916A JP8534068A JP53406896A JPH10504916A JP H10504916 A JPH10504916 A JP H10504916A JP 8534068 A JP8534068 A JP 8534068A JP 53406896 A JP53406896 A JP 53406896A JP H10504916 A JPH10504916 A JP H10504916A
- Authority
- JP
- Japan
- Prior art keywords
- sample
- reflected light
- light beam
- focusing
- reflected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
Landscapes
- Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Microscoopes, Condenser (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Photometry And Measurement Of Optical Pulse Characteristics (AREA)
- Mechanical Optical Scanning Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/438,416 US5578818A (en) | 1995-05-10 | 1995-05-10 | LED point scanning system |
| US438,416 | 1995-05-10 | ||
| PCT/US1996/005120 WO1996036062A1 (en) | 1995-05-10 | 1996-04-09 | Led point scanning system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH10504916A true JPH10504916A (ja) | 1998-05-12 |
| JPH10504916A5 JPH10504916A5 (https=) | 2008-12-25 |
Family
ID=23740573
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8534068A Pending JPH10504916A (ja) | 1995-05-10 | 1996-04-09 | Led点走査システム |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US5578818A (https=) |
| EP (1) | EP0770262A4 (https=) |
| JP (1) | JPH10504916A (https=) |
| WO (1) | WO1996036062A1 (https=) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004053578A (ja) * | 2002-05-29 | 2004-02-19 | Sharp Corp | 光学式物体識別装置および処理システムおよび搬送処理システム |
| JP2005284136A (ja) * | 2004-03-30 | 2005-10-13 | Olympus Corp | 観察装置および観察装置の焦点合わせ方法 |
| JP2016509206A (ja) * | 2012-12-21 | 2016-03-24 | マイクロニクス, インコーポレイテッド | 携帯型蛍光検出システムおよびマイクロアッセイカートリッジ |
| US10065186B2 (en) | 2012-12-21 | 2018-09-04 | Micronics, Inc. | Fluidic circuits and related manufacturing methods |
| US10087440B2 (en) | 2013-05-07 | 2018-10-02 | Micronics, Inc. | Device for preparation and analysis of nucleic acids |
| US10190153B2 (en) | 2013-05-07 | 2019-01-29 | Micronics, Inc. | Methods for preparation of nucleic acid-containing samples using clay minerals and alkaline solutions |
| US10518262B2 (en) | 2012-12-21 | 2019-12-31 | Perkinelmer Health Sciences, Inc. | Low elasticity films for microfluidic use |
| US11016108B2 (en) | 2013-05-07 | 2021-05-25 | Perkinelmer Health Sciences, Inc. | Microfluidic devices and methods for performing serum separation and blood cross-matching |
Families Citing this family (96)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6048734A (en) | 1995-09-15 | 2000-04-11 | The Regents Of The University Of Michigan | Thermal microvalves in a fluid flow method |
| US6068753A (en) * | 1996-05-06 | 2000-05-30 | Helena Laboratories Corporation | Automatic electrophoresis apparatus with fluorescent and visible scanning |
| US5729348A (en) * | 1996-08-21 | 1998-03-17 | Agfa Division, Bayer Corporation | Fluorescence dot area meter |
| US6024020A (en) * | 1996-08-21 | 2000-02-15 | Agfa Corporation | Fluorescence dot area meter for measuring the halftone dot area on a printing plate |
| US5929985A (en) * | 1997-03-18 | 1999-07-27 | Sandia Corporation | Multispectral imaging probe |
| US6005965A (en) * | 1997-04-07 | 1999-12-21 | Komatsu Ltd. | Inspection apparatus for semiconductor packages |
| AU7103598A (en) * | 1997-04-23 | 1998-11-13 | Packard Instrument Company Inc. | Measurement of fluorescence |
| US5929453A (en) * | 1997-06-03 | 1999-07-27 | The United States Of America As Represented By The Secretary Of The Navy | Underwater spectroscopic detector |
| US5895915A (en) * | 1997-07-24 | 1999-04-20 | General Scanning, Inc. | Bi-directional scanning system with a pixel clock system |
| US6043506A (en) * | 1997-08-13 | 2000-03-28 | Bio-Rad Laboratories, Inc. | Multi parameter scanner |
| US6051835A (en) * | 1998-01-07 | 2000-04-18 | Bio-Rad Laboratories, Inc. | Spectral imaging apparatus and methodology |
| US6201639B1 (en) | 1998-03-20 | 2001-03-13 | James W. Overbeck | Wide field of view and high speed scanning microscopy |
| US6185030B1 (en) | 1998-03-20 | 2001-02-06 | James W. Overbeck | Wide field of view and high speed scanning microscopy |
| US6184534B1 (en) * | 1998-08-04 | 2001-02-06 | Eastman Kodak Company | Method of pulsing light emitting diodes for reading fluorescent indicia, data reader, and system |
| US6868433B1 (en) | 1998-09-11 | 2005-03-15 | L.V. Partners, L.P. | Input device having positional and scanning capabilities |
| US6704864B1 (en) | 1999-08-19 | 2004-03-09 | L.V. Partners, L.P. | Automatic configuration of equipment software |
| US6754698B1 (en) | 1998-09-11 | 2004-06-22 | L. V. Partners, L.P. | Method and apparatus for accessing a remote location with an optical reader having a dedicated memory system |
| US7440993B1 (en) | 1998-09-11 | 2008-10-21 | Lv Partners, L.P. | Method and apparatus for launching a web browser in response to scanning of product information |
| US7386600B1 (en) | 1998-09-11 | 2008-06-10 | Lv Partners, L.P. | Launching a web site using a personal device |
| US6877032B1 (en) | 1998-09-11 | 2005-04-05 | L.V. Partners, L.P. | Launching a web site using a portable scanner |
| US7284066B1 (en) | 1998-09-11 | 2007-10-16 | Lv Partners, Lp | Method and apparatus for matching a user's use profile in commerce with a broadcast |
| US7370114B1 (en) | 1998-09-11 | 2008-05-06 | Lv Partners, L.P. | Software downloading using a television broadcast channel |
| US7159037B1 (en) * | 1998-09-11 | 2007-01-02 | Lv Partners, Lp | Method and apparatus for utilizing an existing product code to issue a match to a predetermined location on a global network |
| US7392945B1 (en) | 1998-09-11 | 2008-07-01 | Lv Partners, L.P. | Portable scanner for enabling automatic commerce transactions |
| US6745234B1 (en) | 1998-09-11 | 2004-06-01 | Digital:Convergence Corporation | Method and apparatus for accessing a remote location by scanning an optical code |
| US6636896B1 (en) | 1998-09-11 | 2003-10-21 | Lv Partners, L.P. | Method and apparatus for utilizing an audibly coded signal to conduct commerce over the internet |
| US7536478B2 (en) | 1998-09-11 | 2009-05-19 | Rpx-Lv Acquisition Llc | Method and apparatus for opening and launching a web browser in response to an audible signal |
| US6845388B1 (en) | 1998-09-11 | 2005-01-18 | L. V. Partners, L.P. | Web site access manual of a character string into a software interface |
| US6860424B1 (en) | 1998-09-11 | 2005-03-01 | L.V. Partners, L.P. | Optical reader and use |
| US6823388B1 (en) | 1998-09-11 | 2004-11-23 | L.V. Parners, L.P. | Method and apparatus for accessing a remote location with an optical reader having a programmable memory system |
| US7379901B1 (en) | 1998-09-11 | 2008-05-27 | Lv Partners, L.P. | Accessing a vendor web site using personal account information retrieved from a credit card company web site |
| US7191247B1 (en) | 1998-09-11 | 2007-03-13 | Lv Partners, Lp | Method for connecting a wireless device to a remote location on a network |
| JP2002537667A (ja) | 1998-11-25 | 2002-11-05 | フォーマックス コーポレイション | デュアルヘッド蛍光体スクリーンスキャナ |
| DE19949272C2 (de) | 1999-10-12 | 2003-09-11 | Leica Microsystems | Scanmikroskop |
| US20040224421A1 (en) * | 2000-06-15 | 2004-11-11 | Deweerd Herman | Bi-directional scanning method |
| US7158224B2 (en) * | 2000-06-25 | 2007-01-02 | Affymetrix, Inc. | Optically active substrates |
| US6692700B2 (en) | 2001-02-14 | 2004-02-17 | Handylab, Inc. | Heat-reduction methods and systems related to microfluidic devices |
| US8895311B1 (en) | 2001-03-28 | 2014-11-25 | Handylab, Inc. | Methods and systems for control of general purpose microfluidic devices |
| US7010391B2 (en) | 2001-03-28 | 2006-03-07 | Handylab, Inc. | Methods and systems for control of microfluidic devices |
| US7829025B2 (en) | 2001-03-28 | 2010-11-09 | Venture Lending & Leasing Iv, Inc. | Systems and methods for thermal actuation of microfluidic devices |
| US7323140B2 (en) | 2001-03-28 | 2008-01-29 | Handylab, Inc. | Moving microdroplets in a microfluidic device |
| US6852287B2 (en) | 2001-09-12 | 2005-02-08 | Handylab, Inc. | Microfluidic devices having a reduced number of input and output connections |
| DE10137158B4 (de) * | 2001-07-30 | 2005-08-04 | Leica Microsystems Heidelberg Gmbh | Verfahren zur Scanmikroskopie und Scanmikroskop |
| US7218810B2 (en) * | 2001-09-27 | 2007-05-15 | Bio-Rad Laboratories, Inc. | Biochemical assay detection in a liquid receptacle using a fiber optic exciter |
| US6754414B2 (en) | 2001-09-27 | 2004-06-22 | Bio-Rad Laboratories, Inc. | Imaging of microarrays using fiber optic exciter |
| US7376304B2 (en) * | 2001-09-27 | 2008-05-20 | Bio-Rad Laboratories, Inc. | Biochemical assay detection using a fiber optic exciter |
| GB0209329D0 (en) * | 2002-04-24 | 2002-06-05 | Imp College Innovations Ltd | A device |
| US20030230728A1 (en) * | 2002-06-13 | 2003-12-18 | Zhengshan Dai | Multiwavelength transilluminator for absorbance and fluorescence detection using light emitting diodes |
| US7148043B2 (en) * | 2003-05-08 | 2006-12-12 | Bio-Rad Laboratories, Inc. | Systems and methods for fluorescence detection with a movable detection module |
| WO2004102627A2 (en) * | 2003-05-08 | 2004-11-25 | Alara, Inc. | Method and apparatus for radiation image erasure |
| EP3718635A1 (en) | 2003-07-31 | 2020-10-07 | Handylab, Inc. | Processing particle-containing samples |
| US7151557B2 (en) * | 2004-03-19 | 2006-12-19 | Lexmark International, Inc. | Collimation assembly for adjusting laser light sources in a multi-beamed laser scanning unit |
| ES2553097T3 (es) | 2004-05-03 | 2015-12-04 | Handylab, Inc. | Procesamiento de muestras que contienen polinucleótidos |
| US8852862B2 (en) | 2004-05-03 | 2014-10-07 | Handylab, Inc. | Method for processing polynucleotide-containing samples |
| US8351026B2 (en) | 2005-04-22 | 2013-01-08 | Affymetrix, Inc. | Methods and devices for reading microarrays |
| DE102005031857B8 (de) * | 2005-06-23 | 2006-11-16 | GfG Ges. für Gerätebau mbH | Optisches Analysegerät |
| US7727473B2 (en) | 2005-10-19 | 2010-06-01 | Progentech Limited | Cassette for sample preparation |
| US7754148B2 (en) | 2006-12-27 | 2010-07-13 | Progentech Limited | Instrument for cassette for sample preparation |
| US7329860B2 (en) * | 2005-11-23 | 2008-02-12 | Illumina, Inc. | Confocal imaging methods and apparatus |
| ES2692380T3 (es) | 2006-03-24 | 2018-12-03 | Handylab, Inc. | Método para realizar PCR con un cartucho con varias pistas |
| US11806718B2 (en) | 2006-03-24 | 2023-11-07 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
| US8088616B2 (en) * | 2006-03-24 | 2012-01-03 | Handylab, Inc. | Heater unit for microfluidic diagnostic system |
| US7998708B2 (en) | 2006-03-24 | 2011-08-16 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
| US10900066B2 (en) | 2006-03-24 | 2021-01-26 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
| US8765076B2 (en) | 2006-11-14 | 2014-07-01 | Handylab, Inc. | Microfluidic valve and method of making same |
| WO2008060604A2 (en) | 2006-11-14 | 2008-05-22 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
| US7791013B2 (en) * | 2006-11-21 | 2010-09-07 | Illumina, Inc. | Biological microarray line scanning method and system |
| US7813013B2 (en) * | 2006-11-21 | 2010-10-12 | Illumina, Inc. | Hexagonal site line scanning method and system |
| CA2677009A1 (en) * | 2007-02-06 | 2008-08-14 | Glumetrics, Inc. | Optical systems and methods for rationmetric measurement of blood glucose concentration |
| US8287820B2 (en) | 2007-07-13 | 2012-10-16 | Handylab, Inc. | Automated pipetting apparatus having a combined liquid pump and pipette head system |
| US8105783B2 (en) | 2007-07-13 | 2012-01-31 | Handylab, Inc. | Microfluidic cartridge |
| AU2008276211B2 (en) | 2007-07-13 | 2015-01-22 | Handylab, Inc. | Polynucleotide capture materials, and methods of using same |
| US9186677B2 (en) | 2007-07-13 | 2015-11-17 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
| US8182763B2 (en) | 2007-07-13 | 2012-05-22 | Handylab, Inc. | Rack for sample tubes and reagent holders |
| US8133671B2 (en) | 2007-07-13 | 2012-03-13 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
| USD621060S1 (en) | 2008-07-14 | 2010-08-03 | Handylab, Inc. | Microfluidic cartridge |
| US9618139B2 (en) | 2007-07-13 | 2017-04-11 | Handylab, Inc. | Integrated heater and magnetic separator |
| US20090136385A1 (en) | 2007-07-13 | 2009-05-28 | Handylab, Inc. | Reagent Tube |
| WO2009091902A1 (en) * | 2008-01-17 | 2009-07-23 | The Salk Institute For Biological Studies | 3d scanning acousto-optic microscope |
| US8194240B1 (en) * | 2008-03-04 | 2012-06-05 | Kla-Tencor Corporation | Enhanced focusing capability on a sample using a spot matrix |
| US20090236541A1 (en) * | 2008-03-24 | 2009-09-24 | General Electric Company | System and Methods for Optical Imaging |
| EP2108991A1 (en) * | 2008-04-08 | 2009-10-14 | PerkinElmer Cellular Technologies Germany GmbH | Scanning Microscope |
| USD618820S1 (en) | 2008-07-11 | 2010-06-29 | Handylab, Inc. | Reagent holder |
| USD787087S1 (en) | 2008-07-14 | 2017-05-16 | Handylab, Inc. | Housing |
| WO2010075385A2 (en) * | 2008-12-23 | 2010-07-01 | Tufts University | Methods and system for confocal light scattering spectroscopic imaging |
| KR20160088958A (ko) | 2010-02-23 | 2016-07-26 | 루미넥스 코포레이션 | 일체화된 샘플 제조, 반응 및 검출을 위한 장치 및 방법 |
| WO2012074472A1 (en) * | 2010-11-30 | 2012-06-07 | Ge Healthcare Bio-Sciences Ab | A luminescence detection scanner and a method for detecting luminescence |
| JP6088487B2 (ja) | 2011-04-15 | 2017-03-01 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | 走査リアルタイムマイクロ流体熱サイクラーと同期熱サイクリング及び走査光学検出の方法 |
| CN104023834B (zh) | 2011-05-04 | 2016-09-28 | 卢米耐克斯公司 | 用于集成的样品制备、反应和检测的设备与方法 |
| USD692162S1 (en) | 2011-09-30 | 2013-10-22 | Becton, Dickinson And Company | Single piece reagent holder |
| RU2622432C2 (ru) | 2011-09-30 | 2017-06-15 | Бектон, Дикинсон Энд Компани | Унифицированная полоска для реактивов |
| WO2013067202A1 (en) | 2011-11-04 | 2013-05-10 | Handylab, Inc. | Polynucleotide sample preparation device |
| AU2013214849B2 (en) | 2012-02-03 | 2016-09-01 | Becton, Dickinson And Company | External files for distribution of molecular diagnostic tests and determination of compatibility between tests |
| CN103018208B (zh) * | 2012-12-07 | 2016-04-20 | 清华大学深圳研究生院 | 一种光扫描散射仪 |
| CN103543476B (zh) * | 2013-10-12 | 2016-06-15 | 杭州芬得检测技术有限公司 | 一种爆炸品和毒品探测器 |
| CN110118757B (zh) * | 2018-02-05 | 2021-07-06 | 北京信息科技大学 | 用于共聚焦式led诱导荧光检测的光源补偿方法及装置 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4827125A (en) * | 1987-04-29 | 1989-05-02 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Confocal scanning laser microscope having no moving parts |
| CA1325537C (en) * | 1988-08-01 | 1993-12-28 | Timothy Peter Dabbs | Confocal microscope |
| US5151580A (en) * | 1990-08-03 | 1992-09-29 | Symbol Technologies, Inc. | Light emitting diode scanner |
| US5190857A (en) * | 1989-05-19 | 1993-03-02 | Acrogen, Inc. | Optical method for measuring an analyte using area-modulated luminescence |
| JP2663195B2 (ja) * | 1989-09-22 | 1997-10-15 | 富士写真フイルム株式会社 | 共焦点走査型顕微鏡 |
| US5091652A (en) * | 1990-01-12 | 1992-02-25 | The Regents Of The University Of California | Laser excited confocal microscope fluorescence scanner and method |
| US5323009A (en) * | 1990-04-06 | 1994-06-21 | Harris Martin R | Conforcal microscope |
| US5125746A (en) * | 1990-06-07 | 1992-06-30 | Harold Lipshitz | Surface topography measurement apparatus and method |
| GB9014263D0 (en) * | 1990-06-27 | 1990-08-15 | Dixon Arthur E | Apparatus and method for spatially- and spectrally- resolvedmeasurements |
| US5386112A (en) * | 1990-06-29 | 1995-01-31 | Dixon; Arthur E. | Apparatus and method for transmitted-light and reflected-light imaging |
| JP2613130B2 (ja) * | 1990-10-19 | 1997-05-21 | 富士写真フイルム株式会社 | 共焦点走査型位相差顕微鏡 |
| JPH04157413A (ja) * | 1990-10-20 | 1992-05-29 | Fuji Photo Film Co Ltd | 走査型顕微鏡 |
| US5157249A (en) * | 1991-02-19 | 1992-10-20 | Olympus Optical Co., Ltd. | Miniaturized optical pick-up with high sensitivity focusing error detecting device |
| JPH0527177A (ja) * | 1991-07-25 | 1993-02-05 | Fuji Photo Film Co Ltd | 走査型顕微鏡 |
| JP2787678B2 (ja) * | 1992-04-24 | 1998-08-20 | 聡 河田 | 偏光顕微鏡 |
| US5381224A (en) * | 1993-08-30 | 1995-01-10 | A. E. Dixon | Scanning laser imaging system |
| US5377004A (en) * | 1993-10-15 | 1994-12-27 | Kaiser Optical Systems | Remote optical measurement probe |
-
1995
- 1995-05-10 US US08/438,416 patent/US5578818A/en not_active Expired - Lifetime
-
1996
- 1996-04-09 JP JP8534068A patent/JPH10504916A/ja active Pending
- 1996-04-09 WO PCT/US1996/005120 patent/WO1996036062A1/en not_active Ceased
- 1996-04-09 EP EP96911747A patent/EP0770262A4/en not_active Withdrawn
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004053578A (ja) * | 2002-05-29 | 2004-02-19 | Sharp Corp | 光学式物体識別装置および処理システムおよび搬送処理システム |
| JP2005284136A (ja) * | 2004-03-30 | 2005-10-13 | Olympus Corp | 観察装置および観察装置の焦点合わせ方法 |
| JP2016509206A (ja) * | 2012-12-21 | 2016-03-24 | マイクロニクス, インコーポレイテッド | 携帯型蛍光検出システムおよびマイクロアッセイカートリッジ |
| US10065186B2 (en) | 2012-12-21 | 2018-09-04 | Micronics, Inc. | Fluidic circuits and related manufacturing methods |
| US10436713B2 (en) | 2012-12-21 | 2019-10-08 | Micronics, Inc. | Portable fluorescence detection system and microassay cartridge |
| US10518262B2 (en) | 2012-12-21 | 2019-12-31 | Perkinelmer Health Sciences, Inc. | Low elasticity films for microfluidic use |
| US11181105B2 (en) | 2012-12-21 | 2021-11-23 | Perkinelmer Health Sciences, Inc. | Low elasticity films for microfluidic use |
| US10087440B2 (en) | 2013-05-07 | 2018-10-02 | Micronics, Inc. | Device for preparation and analysis of nucleic acids |
| US10190153B2 (en) | 2013-05-07 | 2019-01-29 | Micronics, Inc. | Methods for preparation of nucleic acid-containing samples using clay minerals and alkaline solutions |
| US11016108B2 (en) | 2013-05-07 | 2021-05-25 | Perkinelmer Health Sciences, Inc. | Microfluidic devices and methods for performing serum separation and blood cross-matching |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0770262A4 (en) | 1998-09-09 |
| EP0770262A1 (en) | 1997-05-02 |
| US5578818A (en) | 1996-11-26 |
| WO1996036062A1 (en) | 1996-11-14 |
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