JPH10298149A - Dispersion of quaternary ammonium salt at high concentration and its preparation - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a quaternary ammonium salt dispersion at a high concentration, excellent in usability due to its improved fluidity in spite of the quaternary ammonium salt contained at a high concentration by suppressing a rise in viscosity caused by compounding the quaternary ammonium salt at the high concentration and utilizable as a concentrated type product which is a product such as a hair care product, e.g. especially a hair rinse agent or a hair treatment or a textile treating agent, e.g. a softening agent and to provide a method for preparing the dispersion. SOLUTION: This quaternary ammonium salt dispersion at a high concentration is prepared by compounding a sugar alcohol as a viscosity reducing agent in an amount of 0.5-20 wt.% based on the whole dispersion in the quaternary ammonium salt dispersion at the high concentration containing endoplasmic reticula in which an oily substance is sealed in a bimolecular membrane structure of the quaternary ammonium salt in an aqueous liquid at 5-60 wt.% quaternary ammonium salt concentration.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

The present invention relates to a hair care product such as a hair rinsing agent and a hair treatment agent containing a quaternary ammonium salt at a high concentration, and a fiber treatment agent such as a softening agent for imparting flexibility to fibers and clothing. High concentration quaternary ammonium salt dispersion suitably used for, and the preparation method thereof,
In particular, the present invention relates to a high-concentration quaternary ammonium salt dispersion in which an increase in viscosity caused by a high quaternary ammonium salt concentration is suppressed, and a method for preparing the same.

[0002]

2. Description of the Related Art Conventionally, a dispersion obtained by dispersing a quaternary ammonium salt in an aqueous liquid has been used for hair care products such as hair rinse agents and hair treatment agents, and fiber treatment agents such as softeners. Such products are preferably used as products or as raw materials of products, but in recent years, in these products, the tendency of high concentration has been increasing due to demands such as cost reduction during production and transportation, usability of consumers and the like. There is a need for a technique for increasing the concentration of a quaternary ammonium salt in a dispersion and using it as a concentrated product.

However, if the quaternary ammonium salt is to be dispersed in the aqueous liquid at a high concentration, the viscosity of the system becomes high due to the interaction between particles of the quaternary ammonium salt and the like, and the handling and use of the system become difficult. Sex was a problem. As a method of reducing the viscosity of such a quaternary ammonium salt dispersion, a method of reducing the viscosity by adding an inorganic salt to an aqueous phase in the production process of the quaternary ammonium salt dispersion has been conventionally known. However, in the case of this method, when the concentration of the quaternary ammonium salt is increased, the amount of the inorganic salt to be added must be increased.
This has also affected the stability of the preparation, causing problems such as separation over time.

SUMMARY OF THE INVENTION The present invention has been made in view of the above circumstances, and suppresses the increase in viscosity of a system caused by a high quaternary ammonium salt concentration without impairing formulation stability and the like. It is an object of the present invention to provide a high-concentration quaternary ammonium salt dispersion which can be suitably used as a fiber treatment agent and the like, and a method for preparing the same.

[0005]

Means for Solving the Problems and Embodiments of the Invention As a result of intensive studies to solve the above-mentioned problems, the present inventor has found that when a quaternary ammonium salt is dispersed in an aqueous solution at a high concentration, a high concentration is required. The quaternary ammonium salt in the compounding amount forms a vesicle encapsulating oil in its bilayer membrane structure, and dispersing this vesicle in an aqueous liquid not only provides excellent stability of the dispersion, but also disperses it during use. Attention has been paid to the fact that a high-concentration quaternary ammonium salt dispersion having good properties can be obtained, and as a result of further intensive studies, it has been found that a sugar alcohol is added to such a quaternary ammonium salt vesicle dispersion. In addition, when the concentration of the quaternary ammonium salt is high, the increase in viscosity of the system can be suppressed, and not only a dispersion liquid excellent in handleability and usability can be obtained, but also when the vesicles are dispersed in an aqueous liquid. Dispersibility It can be improved, found that high concentrations quaternary ammonium salt dispersion with more excellent dispersion stability can be obtained, leading to completion of the present invention.

That is, according to the present invention, vesicles in which oil is encapsulated in a bilayer structure of a quaternary ammonium salt are dispersed in an aqueous liquid, and the quaternary ammonium salt concentration is 5 to 60.
A high-concentration quaternary ammonium salt characterized in that a sugar alcohol is added as a viscosity reducing agent in an amount of 0.5 to 20% by weight based on the entire dispersion in a high-concentration quaternary ammonium salt dispersion having a weight percentage of After kneading the dispersion, and a system comprising a quaternary ammonium salt, an oil component, and a first aqueous phase to form a liquid crystal composition, a second aqueous phase is added to the liquid crystal composition;
By kneading, the vesicles in which the oil is incorporated in the bilayer structure of the quaternary ammonium salt are dispersed in the aqueous liquid composed of the first and second aqueous phases, and
When preparing a high-concentration quaternary ammonium salt dispersion having a quaternary ammonium salt concentration of 5 to 60% by weight, a sugar alcohol as a viscosity reducing agent is added to the first aqueous phase and / or the second aqueous phase. A method for preparing a high-concentration quaternary ammonium salt dispersion, characterized by lowering the viscosity of the high-concentration quaternary ammonium salt dispersion by mixing so as to be 0.5 to 20% by weight of the whole. provide.

Hereinafter, the present invention will be described in more detail. The high-concentration quaternary ammonium salt dispersion of the present invention forms vesicles in which oil is enclosed in a quaternary ammonium salt bilayer structure. By dispersing the endoplasmic reticulum in the aqueous liquid, the quaternary ammonium salt is stably compounded at a high concentration, and the viscosity increase is suppressed by the addition of the sugar alcohol.

Here, the quaternary ammonium salt of the present invention is, for example, a compound incorporated as a surfactant or a soft base in a hair care product such as a hair rinse agent or a hair treatment agent, or a fiber treatment agent such as a softener. In this case, the type is not particularly limited, but for example, one or more selected from di- or mono-long-chain alkyl-type quaternary ammonium salts represented by the following general formula (1) are preferably used.

[0009]

Embedded image

In the above formula, R ¹ is an alkyl or alkenyl group having 10 to 25, preferably 14 to 24 carbon atoms;
R ² is an alkyl group having 1 to 3 carbon atoms, or 10 to 2 carbon atoms.
4, preferably 14-18 alkyl or alkenyl groups. Here, each of R ¹ and R ² may be unsubstituted, and —O—, —CONH—, —COO—
May be separated by an ester group or an amide group, or substituted with -OH or the like. R ³ and R ⁴ are an alkyl group or a hydroxyalkyl group having 1 to 4 carbon atoms, respectively, and X is a halogen atom or a monoalkyl sulfate group.

The saturated / unsaturated ratio of the long hydrocarbon chains (R ¹ and R ² ) in the above formula is not particularly limited.

Specific examples of the quaternary ammonium salts include di-hardened tallow alkyl dimethyl ammonium chloride, di-tallow alkyl dimethyl ammonium bromide, dioleyl dimethyl ammonium chloride, dipalmityl methyl hydroxyethyl ammonium methyl sulfate, and distearyl methyl. Polyoxyethylene (average degree of polymerization: 3 mol) ammonium chloride, diisostearyl dimethyl ammonium methyl sulfate,
Dieicosyldimethylammonium chloride, dibehenylmethylpolyoxyethylene (average degree of polymerization: 5 mol) ammonium chloride, dielsyldimethylammonium chloride, di [(2-dodecanoylamino) ethyl] dimethylammonium chloride, di [(2-stearoyl Amino) propyl] dimethylammonium ethyl sulfate, di (2-ethylpalmitoyl) hydroxyethylmethylammonium methylsulfate, trioleylmethylammonium chloride, dioleylmonostearylmethylammonium chloride, dioleylmonobehenylmethylammonium chloride, monooleyldiethylsilylmethyl Ammonium chloride,
Tristearylmethylammonium methyl sulfate, methyl-1-tallowamidoethyl-2-tallowalkylimidazolinium methyl sulfate, methyl-1-hexadecanoylamidoethyl-2-pentadecylimidazolinium chloride, ethyl-1-octadece Distearoyloxyethyldimethylammonium as a quaternary ammonium salt having a long-chain alkyl group or alkenyl group interrupted by another ester group or amide group such as noylamidoethyl-2-heptadecenylimidazolinium ethyl sulfate Chloride, dioleoyloxyethyldimethylammonium chloride, dipalmitoyloxyethyldimethylammonium methyl sulfate, distearoyloxyisopropyldimethylammonium chloride Can be exemplified dioleoyloxy Isopropyl dimethyl ammonium chloride, dioleoyloxy-butyl dimethyl ammonium chloride, stearoyl trimethyl ammonium chloride, oleoyl trimethyl ammonium chloride and the like.

The concentration of the quaternary ammonium salt in the dispersion of the present invention is 5 to 60% (% by weight, the same applies hereinafter), preferably 10 to 40%, more preferably 10 to 30%. If the concentration of the quaternary ammonium salt is too low,
The purpose of the present invention is to suppress the increase in viscosity caused by the increase in the concentration of the quaternary ammonium salt, which departs from the object of the present invention, and cannot be used as a concentrated product. On the other hand, if the concentration is too high, the viscosity reducing effect is reduced.

The oil component which forms vesicles together with the quaternary ammonium salt may be any one which is blended as an oil component such as a hair care product such as a hair rinse agent or a hair treatment agent, or a fiber treatment agent such as a softener. The type is not particularly limited, for example, oil-soluble fragrance, silicone oil,
Oil-soluble antibacterial agents, liquid paraffin, cetyl alcohol, stearyl alcohol, olein alcohol, solid paraffin and the like can be mentioned.
More than one species can be used in appropriate combination.

The blending amount of the oil component in the dispersion of the present invention is appropriately selected depending on the type, purpose and use of the dispersion, and is usually 0.1 to 3 with respect to the entire dispersion.
It is desirably 0%, particularly 0.3 to 12%. If the amount of the oil component is too small, the effect of the oil component may not be sufficiently obtained, and if the amount of the oil component is too large, it may be difficult to form vesicles. The mixing ratio of the oil to the quaternary ammonium salt is preferably more than 0%, 50% or less, particularly more than 0% and 20% or less of the quaternary ammonium salt. Is too large, vesicles composed of quaternary ammonium salts containing oil may be broken.

The high-concentration quaternary ammonium salt dispersion of the present invention is used together with the quaternary ammonium salt to form ethylene glycol, propylene glycol, and glycerin in order to facilitate the formation of a film with the quaternary ammonium salt. Organic solvents such as polyhydric alcohols such as ethanol, isopropyl alcohol, etc., fatty acids such as stearic acid and oleic acid, various emulsifiers such as polyoxyethylene alkyl ethers, sorbitan fatty acid esters, and polyoxyethylene sorbitan fatty acid esters, and fatty acids. Additives such as alkanolamines can be blended in the usual amounts.

The aqueous liquid in which the vesicles comprising the quaternary ammonium salt and the oil are dispersed is not only water, but also emulsifiers, dispersion stabilizers, low-temperature stabilizers, inorganic salts, pigments and other water. And a solution in which the various water-soluble active ingredients described above are dissolved in an appropriate amount within a range not to impair the effects of the present invention. Specifically, polyoxyethylene nonyl phenyl ether, polyoxyethylene octyl phenyl ether, glycerin fatty acid ester,
Nonionic surfactants such as polyoxyethylene sorbitan fatty acid esters, polyoxyethylene alkyl ethers and fatty acid polyethylene glycols; dispersion stabilizers such as polyacrylic acid, carboxymethyl cellulose and carboxyvinyl polymers; low temperature stabilizers such as ethylene glycol; Acid red 138, acid blue 9, acid yellow 141, reactive blue, and other various water-soluble pigments such as propylene glycol, glycerin, inorganic salts such as sodium chloride, calcium chloride, etc., and sulfates such as sodium sulfate. Examples of the active ingredient include a bactericide, an antibacterial agent, an antioxidant, an ultraviolet absorber, and a fluorescent whitening agent.

In the present invention, the type of sugar alcohol which acts as a viscosity reducing agent is particularly limited as long as it can be incorporated into hair care products such as hair rinse agents and hair treatment agents, and fiber treatment agents such as softeners. Examples of such sugar alcohols include, for example, sorbitol, mannitol, glycitol, tallit, alit, tetrit, erythrit, glucose, fructose, idit, galactit, pentit, xylit, hexit, and the like. Can be used alone or in an appropriate combination of two or more. In the case of the present invention, among these, sorbitol is particularly preferably used.

The amount of the sugar alcohol is 0.5 to 20%, preferably 2 to 16%, more preferably 4 to 10%, based on the whole dispersion. If the amount is too small, the effect of reducing the viscosity cannot be obtained. If the amount is too large, no further effect can be obtained, which is uneconomical. The mixing ratio of the sugar alcohol to the quaternary ammonium salt is preferably 5 to 80%, more preferably 10 to 60%, particularly preferably 15 to 50% of the quaternary ammonium salt. If the blending ratio of alcohol is too large, no further blending effect can be obtained, which may be uneconomical,
If the mixing ratio of the sugar alcohol is too small, the viscosity reducing effect may not be obtained.

The quaternary ammonium salt dispersion of the present invention comprises:
As described above, by adding the predetermined amount of the sugar alcohol, the viscosity of the dispersion is suppressed from increasing due to the quaternary ammonium salt being highly blended. In the case of the quaternary ammonium salt dispersion of the present invention, Compared to the vesicle dispersion having the same composition except that the sugar alcohol is not blended, the blending amount of sugar alcohol is usually 0.1% of the whole dispersion, though depending on the combination of the quaternary ammonium salt and the sugar alcohol. As it increases from 5 to 20%, the viscosity of the dispersion decreases from 1/8 to 1/65. The viscosity of the quaternary ammonium salt dispersion of the present invention varies depending on the type, blending amount, composition and the like of the quaternary ammonium salt. When the viscosity is measured after rotating the rotor at 30 rpm for 20 seconds, the viscosity is usually 1,500 cP (centipoise) or less, particularly preferably 500 cP or less.

The method of preparing the high-concentration quaternary ammonium salt dispersion is not particularly limited, but the high-concentration quaternary ammonium salt dispersion of the present invention utilizing a liquid crystal phase inversion method will be described in detail below. When the method for preparing a quaternary ammonium salt dispersion is adopted, the increase in viscosity over time can be suppressed, and the increase in viscosity of a system in which vesicles are dispersed in an aqueous liquid can be effectively suppressed. This is preferable because a high-concentration quaternary ammonium salt can be easily prepared.

That is, in the method for preparing a high-concentration quaternary ammonium salt dispersion according to the present invention, a liquid crystal composition is formed from the quaternary ammonium salt, an oil, and a first aqueous phase (part of the aqueous liquid). After that, a second aqueous phase (the remainder of the aqueous liquid) is added to the liquid crystal composition and kneaded to prepare a high-concentration quaternary ammonium salt dispersion of the present invention. The predetermined amount of the sugar alcohol is blended with at least one of the first aqueous phase and the second aqueous phase to lower the viscosity of the system.

Here, in the case of the preparation method of the present invention, the mixing procedure of the above components in the step of forming the liquid crystal composition is not particularly limited, but usually, the above predetermined amount of the quaternary ammonium salt and the oil component are used. If necessary, the oil-soluble component in the optional component is melted and mixed to form an oil phase, and a system composed of this oil phase and a first aqueous phase (part of the aqueous liquid) is kneaded to form a liquid crystal composition. It is desirable to form an object. The procedure for blending the sugar alcohol is not particularly limited, and the sugar alcohol can be blended in at least one of the first aqueous phase and the second aqueous phase.

When preparing an aqueous dispersion of the above vesicles,
The mixing ratio of the first aqueous phase to the oil phase is preferably such that the liquid crystal composition is formed immediately before the vesicle is formed from the viewpoint of the formation of the liquid crystal composition and the vesicle conversion ratio of the quaternary ammonium salt. Oil phase / first aqueous phase = 0.5 / 1 to 1
1.6 / 1, especially about 1.0 / 1 to 1.2 / 1, and the first aqueous phase / second aqueous phase = 5/95 to 90/1
An amount that is 0, particularly about 10/90 to 80/20 is preferable.

The temperature at which the liquid crystal composition is formed by kneading the system consisting of the aqueous phase and the oil phase must be equal to or higher than the phase transition temperature (T _c ) of the quaternary ammonium salt. . If the liquid crystal composition formation temperature is _lower than _Tc , no liquid crystal is formed. The temperature difference between the temperature at which the liquid crystal composition is formed and _Tc is not particularly limited and can be appropriately selected within a temperature range in which liquid crystal can be formed. 2~20 ℃ than _c, in particular 2 to 10
It is desirable that the temperature is higher by about ° C.

When the liquid crystal composition is formed from the above system, the kneading apparatus to be used is not particularly limited, and a conventionally used apparatus can be used, but the viscosity of the system is such that the liquid crystal composition is formed. Considering that
It is desirable to be able to mix the high-viscosity material as a whole, and as such a device, for example, a line mixer, an azihomo mixer, a kneader, a paddle mixer, a screw mixer,
Examples include a spiral mixer, a Nauter mixer, a double helical ribbon mixer, and a continuous kneader. The kneading conditions at this time are within the normal use range of these devices, and it is desirable to continue stirring until the liquid crystal composition is formed and the viscosity of the system becomes high.

In the case of the above method, a liquid crystal composition is formed from the above system by such a kneading step.
Whether or not a liquid crystal composition was formed in such a step
It can be confirmed by utilizing the change (increase) in the viscosity of the system due to the formation of the liquid crystal composition.

The system in which the liquid crystal composition was formed was frozen and then cut, and the surface of the cut surface was taken and observed with a transmission electron microscope. The presence of a multilayer structure was observed. It is recognized as a lamellar liquid crystal formed by a bilayer film of an ammonium salt and an aqueous layer composed of the above aqueous phase.

Next, the liquid crystal composition and the second aqueous phase are mixed to obtain a desired high-concentration quaternary ammonium salt dispersion (vesicle dispersion). In this case, the mixing temperature is as follows: Although it can be produced at a temperature lower than the phase transition temperature of the quaternary ammonium salt, it is preferable to carry out the reaction at a temperature higher than the phase transition temperature in consideration of the solidification of the quaternary ammonium salt. The order of adding the liquid crystal composition and the second aqueous phase is not particularly limited, and they may be added simultaneously, for example. And the stirrer used for this mixing / dispersion step is not particularly limited,
An apparatus used in a normal emulsification dispersion step can be used, but the dispersed particles (vesicle particles) are uniformly dispersed,
In view of obtaining a composition having excellent separation stability, it is desirable to lengthen the residence time and increase the time required for shearing. Examples of such an apparatus include a line mixer, an azimuth mixer, a homomic line mill, a homomic line flow, a milder, and a disper mixer. The stirring conditions at this time are performed in the normal use range of these devices. In particular, when the peripheral speed at the tip of the stirring blade is used as a representative value of the shearing force, the peripheral speed at the tip of the stirring blade is 8 m / s.
It is preferable to apply the above shearing force.

The temperature at which the high-concentration quaternary ammonium salt dispersion is prepared may be higher than or equal to the phase transition temperature of the quaternary ammonium salt, and may be lower than or equal to the phase transition temperature. The bilayer film of the film multilayer structure may be in a solidified state. Further, cooling may be performed after the dispersion step.

According to the preparation method of the present invention, it is possible to obtain a high-concentration quaternary ammonium salt dispersion in which an increase in viscosity is suppressed by adding a sugar alcohol to an aqueous phase. When the above sugar alcohol is not dissolved in the aqueous phase, the viscosity of the resulting high-concentration quaternary ammonium salt dispersion is usually 1,000 to 26,000 cP. The quaternary ammonium salt dispersion has a viscosity of 60 to 1,500 c
P can be set.

In preparing the dispersion of the present invention, in addition to the above-mentioned components, various components which are usually compounded in the above-mentioned hair care products and fiber finishing agents can be added. When a quaternary ammonium salt having at least one of a long-chain alkyl group and an alkenyl group separated by an ester group or an amide group (hereinafter, referred to as a hydrolyzable ammonium salt) is used as the ammonium salt, it depends on the pH of the dispersion. Is, because the hydrolyzable ammonium salt may cause hydrolysis during storage,
The pH of the dispersion is adjusted with an acidic compound to a pH of 2 to 5, which is a stabilized region of an ester group or an amide group. When such a hydrolyzable ammonium salt is used in the present invention, a high concentration is required. It is desirable to adjust the quaternary ammonium salt dispersion to pH 2 to 5, especially pH 2.5 to 4. In this case, as the acidic compound, for example, an aqueous solution of hydrochloric acid, sulfuric acid, citric acid, phosphoric acid or the like is suitably used. And in the preparation method of the present invention, such p
When performing H adjustment, the pH of the aqueous phase used during liquid crystal formation
It is desirable to adjust the pH of the vesicle dispersion liquid finally obtained to be in the above-mentioned pH range, and if the pH is adjusted during the formation of the liquid crystal in this way, the pH adjustment of the vesicle dispersion liquid only in the final step The storage stability of the hydrolyzable ammonium salt in the dispersion is improved, as well as the increase in viscosity of the system due to the formation of liquid crystal, as compared with the case of performing the method. In addition, when performing pH adjustment at the time of liquid crystal formation, it is preferable to finely adjust the pH in the final step.

In the case of the preparation method of the present invention, the high-concentration quaternary ammonium salt dispersion thus prepared as an aqueous dispersion of endoplasmic reticulum is directly used as the above-mentioned concentrated hair care product or textile finish. Although it can be used, it can be further diluted with the above-mentioned aqueous liquid, if necessary, or the water-soluble component mentioned as an optional component of the above-mentioned aqueous liquid can be added later.

[0034]

According to the high concentration quaternary ammonium salt dispersion of the present invention, the viscosity increase due to the high content of the quaternary ammonium salt is suppressed, and the quaternary ammonium salt is contained at a high concentration. Regardless of its excellent fluidity, it is excellent in usability, especially for hair care products such as hair rinse agents and hair treatment agents, and fiber treatment products such as softeners, which are used as concentrated products. Concentration 4
It is useful as a quaternary ammonium salt dispersion. The method for preparing a high-concentration quaternary ammonium salt dispersion of the present invention is not only suitable for preparing such a high-concentration quaternary ammonium salt dispersion, but also has good fluidity of the system during preparation. As a result, it becomes easy to uniformly disperse the vesicle particles composed of a quaternary ammonium salt, so that a quaternary ammonium salt dispersion having not only the above properties but also excellent dispersion stability can be easily produced. can do.

[0035]

EXAMPLES The present invention will be specifically described below with reference to examples and comparative examples, but the present invention is not limited to the following examples. In the table,% means% by weight.

[Examples 1 to 10 and Comparative Examples 1 and 2] Table 1
And a quaternary ammonium salt and an oil component are melted and mixed so as to have a composition ratio shown in Table 2, and an aqueous phase is prepared so as to have a water phase composition ratio shown in Tables 1 and 2. The components were dissolved in purified water to prepare aqueous phases (aqueous liquids) of Comparative Examples 1 and 2. For Examples 1 to 10, a sugar alcohol (viscosity reducing agent) was added to and dissolved in the aqueous phase so as to have a ratio shown in Table 1 and Table 2, and an aqueous phase was prepared. The first aqueous phase was taken so as to have a ratio of the first aqueous phase / total aqueous phase shown in Tables 1 and 2, and in Comparative Example 1, 1/5 of the aqueous phase was used as the first aqueous phase. For Comparative Example 2, 3/5 of the aqueous phase was taken as the first aqueous phase. In addition, the remainder of the said aqueous phase was used for the 2nd aqueous phase.

Next, the oil phase and the first aqueous phase were each heated to 38 ° C. in advance, and continuously supplied to a line mixer set to the same temperature. For 3, 7 to 10 and Comparative Example 1, an acidic compound (9% hydrochloric acid aqueous solution) not shown in the composition in the table was prepared such that the final production liquid (aqueous dispersion of endoplasmic reticulum) had a pH of 2.5 to 3.5. The mixture was kneaded while being continuously supplied to form a liquid crystal composition. The stirring condition of the line mixer at this time is such that the ratio d / D of the blade diameter d of the stirring blade to the stirring tank diameter D is 0.8.
Using a two-stage set of four inclined blade paddles, shearing was applied at a peripheral speed of the paddle blade tip of 8 m / s, and kneading was performed with an average residence time of 40 seconds.

The liquid crystal composition formed here was added to 38
The second aqueous phase heated to ° C. was continuously supplied to and mixed with the next line mixer set at the same temperature, to obtain an aqueous dispersion of vesicles. Regarding the stirring conditions of the line mixer at this time, a two-stage four-blade turbine in which the ratio d / D of the blade diameter d of the stirring blade to the stirring tank diameter D is 0.5 is used, The peripheral speed is 10m /
While applying shearing as s, mixing with an average residence time of 30 seconds was added to obtain an aqueous dispersion of endoplasmic reticulum, and the concentrated hair rinse agent or concentrated hair treatment agent of Examples 1 to 5 and Comparative Example 1 (high concentration Quaternary ammonium salt dispersion), and the concentrated softeners (high-concentration quaternary ammonium salt dispersion) of Examples 6 to 10 and Comparative Example 2. It should be noted that the concentrated hair rinse agent and the concentrated hair treatment agent are distinguished by a dilution ratio in a subsequent step.

For the high-concentration quaternary ammonium salt dispersions of these Examples and Comparative Examples, the viscosity at 25 ° C. was B
Using an L-type rotational viscometer, rotate the rotor at 30 rpm for 20 minutes.
The viscosity after rotating for 2 seconds was measured. The results are shown in Tables 1 and 2.

[0040]

[Table 1]

[0041]

[Table 2]

According to Table 1, in the case of the present invention (Examples 1 to 5), a dispersion having a quaternary ammonium salt concentration of 5% by weight was prepared by blending 20% by weight of sugar alcohol at the time of liquid crystal formation. (Example 1) has a viscosity of 6c at 25 ° C.
P, and the viscosity at 25 ° C. is 15 even when the concentration of the quaternary ammonium salt is as high as 10 to 40% by weight.
When the sugar alcohol is not blended even when the quaternary ammonium salt concentration is 5% by weight (Comparative Example 1), the viscosity at 25 ° C.
0 cP, while according to Table 2, the present invention (Example 6)
In the case of (10) to (10), the viscosity at 25 ° C. is 1,500 even though the concentration of the quaternary ammonium salt is as high as 30% by weight by blending 1 to 20% by weight of the total sugar alcohol. A vesicle dispersion of ~ 400 cP is obtained while the quaternary ammonium salt concentration is 30
25% by weight (without sugar alcohol) (Comparative Example 2)
Since the viscosity at 2 ° C. becomes 26,000 cP, the viscosity increase of the aqueous dispersion of the endoplasmic reticulum due to the high content of the quaternary ammonium salt can be suppressed by blending the sugar alcohol, and the hair rinse can be performed without impairing the usability. It has been found that it is possible to concentrate agents, hair treatment agents and softeners.

────────────────────────────────────────────────── ─── Continued on the front page (51) Int.Cl. ⁶ Identification symbol FI // A61K 7/06 A61K 7/06 7/08 7/08 (72) Inventor Kazuo Nagai 1-3-3 Honjo, Sumida-ku, Tokyo No. 7 Inside Lion Corporation

Claims (2)

[Claims] 1. An aqueous liquid in which vesicles in which an oil is encapsulated in a bilayer membrane structure of a quaternary ammonium salt are dispersed, and the quaternary ammonium salt concentration is 5 to 60% by weight. In the quaternary ammonium salt dispersion, a sugar alcohol is used as a viscosity reducing agent in an amount of 0.5 to
A high-concentration quaternary ammonium salt dispersion containing 20% by weight. 2. A liquid crystal composition is formed by kneading a system comprising a quaternary ammonium salt, an oil component and a first aqueous phase, and then adding and kneading a second aqueous phase to the liquid crystal composition. ,
The vesicles in which the oil is incorporated in the bilayer structure of the quaternary ammonium salt are dispersed in the aqueous liquid consisting of the first and second aqueous phases, and the quaternary ammonium salt concentration is 5 to 60% by weight. % When preparing a high-concentration quaternary ammonium salt dispersion having a sugar alcohol content of 0.1% in the first aqueous phase and / or the second aqueous phase.
5-20% by weight, and the high concentration 4
A method for preparing a high-concentration quaternary ammonium salt dispersion, characterized by lowering the viscosity of the quaternary ammonium salt dispersion.