JPH10182394A - Dentifrice agent - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a dentifrice agent which has sterilization, plaque removing effects, improving the absorption of medicable ingredients having circulation accelerating effect using a promoting effect of percutaneous absorption through gum, effective in a short time by containing alcoholic extract of Impatience balsamina L. SOLUTION: The alcoholic extract of Impatience balsamina L is obtained by immersing 2-5 pts.wt. of the whole of Impatience balsamina L, petal, seed which are collected, sun dried as needed, cut out, in 10 pts.wt. of aqueous solution of ethyl alcohol of 10 of more alcohol content(e.g. white liquor) for 2 weeks- half a year, then the residue is separated in a process such as dry-mesh process, etc. The dentifrice agent is obtained by containing 5-10wt.%. of this alcoholic extract in conventional dentifrice agent component such as tooth paste, wet dental powder, liquid dentifrice agent, etc. The alcoholic solution of fruits such as Psidium guajava, grape-fruit, tangerine, lemon, etc., extracted in the prescribed extracting liquid is capable of using in place of the alcoholic extract of Impatience balsamina L.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a method for producing a dentifrice by adding an alcohol extract of Fengxian flower or a liquid obtained by extracting a fruit with the alcohol extract of Fengxiang flower.

[0002]

2. Description of the Related Art Conventional dentifrices are prepared by preventing periodontal disease by a bactericidal action and a blood circulation promoting action and by adding a tooth strengthening agent such as sodium monofluorophosphate. The cause of gum diseases such as gingivitis and tooth sonorow, ie, periodontal disease, is bacteria that propagate in plaque. Therefore, bacteria have been sterilized with a synthetic bactericide, plaque has been removed with a toothbrush, and blood circulation has been promoted with vitamin E, but the desired effect has not been obtained. Substances which have an analgesic and anti-inflammatory action, an antioxidant action, a bactericidal action, a plaque removal, a hemostasis, a blood circulation promoting action and a percutaneous absorption promoting action by one kind of plant extract have not been known so far.

[0003]

The major cause of insufficient effectiveness of dentifrice to prevent periodontal disease is that the medicinal component is absorbed more sufficiently than the gum because the contact time between the medicinal component of the dentifrice and the gum is short. It seems to be not done. However, it is not always possible to keep toothpaste in your mouth forever. Therefore, sterilization and plaque removal are performed using a plant extract, and a medicinal ingredient having a blood circulation promoting effect is promoted using a percutaneous absorption promoting effect.
The aim is to improve the absorption from the gums and create a more effective toothpaste in a short time. In order to further enhance the effect, it is intended to strengthen the skin collagen of gums using vitamin C of fruits.

[0004]

SUMMARY OF THE INVENTION In order to achieve the above object, the present invention has focused on an alcohol extract of Fengxian flower. Traditionally, Fengxian has an excellent analgesic and anti-inflammatory effect against rheumatoid arthritis, sciatica and gout. As a result of analysis of this extract, it was found that a substance called kaempferol (a substance having a detoxifying action) and ergosterol were mainly contained in naphthoquinones (a vitamin K-like action). Moreover, biochemical reducing action, bactericidal action, detoxification action,
The present inventors have found that the substance contains substances having an action such as enzymatic proteolytic action, smooth muscle contraction action (blood circulation promoting action), cholesterol dissolving action, percutaneous absorption promotion, and the like. I thought that.

[0005] Enzymatic proteolysis contained in the alcohol extract of Hosenhana decomposes plaque made of protein, prevents germ propagation in plaque by bactericidal action, and suppresses smooth muscle contraction (blood circulation promoting action). It is used for toothpaste because it improves blood circulation by penetrating gums and other medicinal ingredients into the gums by percutaneous absorption promoting action, and improves the blood circulation. Furthermore, since the vitamin C in the fruit is absorbed from the gum without being oxidized by using the Fengsen flower alcohol extract of the fruit,
Gum skin collagen is strengthened to make gums stronger.

[0006]

DESCRIPTION OF THE PREFERRED EMBODIMENTS Preferred embodiments of the present invention will be described below.

[0007] First, the alcohol extract of Fengsen flower used in the present invention will be described.
balsamine L. ) Is an annual plant (including closely related species and subspecies) belonging to the genus Trichoderma serrata and uses the whole plant (species may be used). After collecting the whole grass from summer to autumn and using it as it is or drying it in the sun,
Fruits are collected before maturity, dried in the sun, and only seeds are collected after drying. The components are naphthoquinones, anthocyanins and thianidine for flowers, kaempferol for foliage,
Contains quercetin, etc.
It is known to contain fatty oils and ergosterol, and is said to have the effect of purifying blood and expanding blood vessels. The Fengxian flower may be collected during the flowering stage and shaded for 2 to 5 days.
The cut whole plant and petals are immersed in an alcohol-containing aqueous solution having an alcohol content of 10 degrees or more.

[0008] The alcohol used in the present invention is preferably an aqueous solution containing an ethialcohol of 10 degrees or more in order to extract the active ingredient of the whole plant of Hosenbana. , Synthetic liquor, white liquor (shochu) and the like may be used. In addition, a methyl alcohol-containing aqueous solution or an isopropyl alcohol-containing aqueous solution having a temperature of 10 degrees or more can be used depending on the application.

The mixing ratio is preferably 2 to 5 parts by weight with respect to 10 parts by weight of white liquor. Soak for 2 weeks to 6 months, preferably for 6 months to 1 month. After the immersion, the residue is separated by means such as a dry mesh method to obtain an alcohol extract of Fengxian flower. This Hosensen alcohol extract contains naphthoquinone derivatives (vitamin K-like action), kaempferol (a precursor of naphthoquinone), flavonoids, ergosterol (vitamin D ₂
As a main component. Further, it has a feature that the pH is close to the pH of human blood (about 7.4) (7.2). Furthermore, this Fengxian alcohol extract can also convert substances that should be oily (hydrophobic) to water-soluble (hydrophilic) under a certain ratio of water and fat (oil). Emulsion).

[0010] Various functions are listed below, including analgesic and anti-inflammatory effects, vitamin K-like effects, biochemical reduction effects, bactericidal effects,
Detoxification, enzymatic proteolysis, smooth muscle contraction (blood circulation promotion), percutaneous absorption, cholesterol dissolution, etc. Among them, the dentifrices are useful for analgesic and anti-inflammatory, vitamin K-like, It is a biochemical reducing action, a bactericidal action, an enzymatic protein degradation action, a smooth muscle contraction action (blood circulation promoting action), and a percutaneous absorption promotion.

[0011] Toothpaste refers to toothpaste, moisturizing toothpaste, water dentifrice, and fruit refers to guava, grapefruit, tangerine, lemon and the like containing vitamin C. Hosenka alcohol extract,
Alternatively, the amount of the alcohol extract of Fengxian flower is 5 to 10% by weight based on the total weight of the dentifrice.

Next, a method for manufacturing toothpaste will be described with reference to examples.

Embodiment 1 FIG. Toothpaste, 23.9 g of purified water, 5 g of alcoholic extract of mandarin orange flower, 1 g of carboxymethylcellulose and 0.3 g of Irish moss are added and dissolved. 45 g of potassium phosphate dihydrate, 2 g of silicic anhydride, 10 g of glycerin, 10 g of sorbitol,
1.8 g of sodium lauryl sulfate, 1 g of a flavor and a sweetener are added, mixed uniformly, degassed and filled in a tube.

Embodiment 2 FIG. Lubricious toothpaste, 3 g of Hosenhana alcohol extract, 40 g of heavy calcium carbonate, 40 g of light calcium carbonate, 15 g of glycerin, 1.5 g of sodium lauryl sulfate, 1.2 g of flavor, sweetener and coloring are added and mixed uniformly.

Embodiment 3 FIG. Water dentifrice, 3 g of Hosensen alcohol extract, 5 g of glycerin, 1 g of sodium lauryl sulfate, 5 g of sorbitol, 12 g of ethyl alcohol, 74 purified water
g, copper chlorophyllin soda, sweetener, and flavor, and mix uniformly.

[0016]

The alcohol extract of Fengxian flower contains analgesic and anti-inflammatory effects, vitamin K-like effects, biochemical reduction effects, bactericidal effects, enzymatic protein degradation effects, smooth muscle contraction effects (blood circulation promoting effects), transdermal Has absorption promoting action.

As a result, the swelling of the gums and the pain are cured by the analgesic and anti-inflammatory effect. Vitamin K-like action stops bleeding gums. Vitamin E, Vitamin C by biochemical reduction
Prevents oxidation and maintains medicinal properties. The bactericidal action kills bacteria that grow on plaque and eliminates the need for preservatives in the product. Degrades and removes plaque by enzymatic proteolysis. The smooth muscle contraction action (blood circulation promoting action) promotes the blood circulation of the gums and turns them into pink gums. With percutaneous absorption promotion action,
It absorbs easily reducible medicinal ingredients such as vitamin E and vitamin C more quickly than gums, increasing its effect. Vitamin C contained in the fruit enters the body without being oxidized, and contributes to the production of collagen to strengthen gum skin.

Claims (3)

[Claims] 1. A method for producing dentifrice, comprising adding an alcohol extract of Hosenhana to the dentifrice. 2. A method for producing a toothpaste, comprising adding a fruit extract extracted with an alcoholic extract of Hosenka to the toothpaste. 3. The alcohol extract of Fengxian flower is added to 10 parts by weight of an aqueous solution containing ethyl alcohol of 10 ° C. or more,
3. The method for producing a dentifrice according to claim 1, wherein about 5 parts by weight of whole herb is immersed and the residue is separated.