JP2001172143A - Hair dyeing composition - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a hair dye composition having high safety for human bodies and capable of slowly exhibiting hair dyeing effects by a simple method for using. SOLUTION: This hair dyeing composition is characterized as comprising a proanthocyanidine.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a hair dye composition containing a polymer containing a flavan-7-ol or a derivative thereof as an essential constituent monomer. More specifically, the present invention relates to a hair dye composition capable of gradually dyeing gray hair by daily use. More specifically, the safety to the human body is high,
In addition, the present invention relates to a hair dye composition that can gradually exert a hair dyeing effect by a simple method of use.

[0002]

2. Description of the Related Art Most hair dyes are obtained by oxidizing an oxidation dye mainly composed of p-phenylenediamines on hair with an oxidizing agent such as hydrogen peroxide, and then subjecting the dye to a coupling reaction with a coupler such as resorcinol. The hair is dyed and dyed. In this method, if an oxidation dye and an oxidizing agent are made to coexist with water before being applied to hair, an oxidation reaction proceeds, and the hair dyeing effect is reduced when applied to hair. Accordingly, the oxidation dye and the oxidizing agent are mixed as a non-aqueous powder, and the mixed powder is mixed with water at the time of use, or a one-pack type in which the oxidation dye is dissolved in an organic solvent, and the oxidizing agent. Hair dyeing has been performed in one of two-part types in which a second agent containing water and water is mixed at the time of use.

[0003] In addition, a method of dyeing hair by reacting tannic acid, gallic acid, pyrogallol, dopa, hematein and the like with a polyvalent metal salt such as ferrous sulfate on the hair is usually referred to as a rice cake type. Are known.

Proanthocyanidins, which are polymers of flavan-7-ols, are antioxidants (JP-A-61-169).
No. 82) and a hair restorer (Republished No. 96-00561), but the hair dyeing effect of proanthocyanidins is not known.

[0005]

In a method of dyeing hair using an oxidation dye and an oxidizing agent, the hair dye is mixed with the hair at the time of use in either one-pack type or two-pack type with time. Power drops. Therefore, the hair dyeing operation must be completed quickly in a short time by using a dedicated device immediately before use, and there is a problem in the simplicity of the hair dyeing operation. In addition, oxidation dyes contain potentially sensitizing substances, may show contact allergic action and carcinogenicity, and some oxidizing agents have very strong irritation to skin, especially mucous membranes and eyes. There was a risk of causing skin damage. Further, there is a problem that the color tone of the hair changes remarkably before and after the hair dyeing, and a third party feels unnatural.

On the other hand, in the method of dyeing hair using a rice ball type, since the reaction proceeds gently, hair can be dyed gradually under mild conditions, and the operation is simple. However, pyrogallol, hematein and the like, as well as the reduced form thereof, are considered to exhibit carcinogenicity, and thus pose a problem in safety. In addition, there is a problem that the color tone of the hair after dyeing is unnatural to a third party.

[0007] The present invention is intended to solve the above-mentioned problems of the prior art, and has high safety to the human body and is capable of gradually exhibiting a hair dyeing effect by a simple method of use. It is intended to provide a composition.

[0008]

DISCLOSURE OF THE INVENTION The present inventors have found that a polymer containing a flavan-7-ol or a derivative thereof as an essential constituent monomer has high safety, and that the flavan-7-ol has high safety. The present inventors have found that a hair containing a polymer or a derivative thereof as an essential constituent monomer can be dyed gradually by routinely applying it to hair, thereby completing the present invention.

That is, the present invention is a hair dyeing composition comprising a polymer containing a flavan-7-ol or a derivative thereof as an essential constituent monomer.

[0010]

BEST MODE FOR CARRYING OUT THE INVENTION The flavan-7-ol used in the present invention in a polymer containing a flavan-7-ol or a derivative thereof as an essential constituent monomer is represented by the general formula (1).

[0011]

Embedded image (Wherein, R1 and R2 independently represent a hydrogen atom, a hydroxyl group, or a galloyl group, and R3, R4, R5, R
6 and R7 independently represent a hydrogen atom or a hydroxyl group. )

Specific examples of the flavan-7-ols represented by the formula (1) include catechin, epicatechin, gallocatechin, epigallocatechin, afseletin, epiafuseletin and the like, and all of these optical isomers are included. It is. Specific examples of the flavan-7-ol derivatives include luteolin and glycosides thereof.

The proanthocyanidin used in the present invention may be a dimer or more of a flavan-7-ol derivative, preferably a dimer to a dimer, more preferably a dimer of a flavan-7-ol derivative.
It is a pentamer, more preferably a dimer to a trimer. In addition, proanthocyanidins in which flavan-7-ols are composed of epicatechin or catechin as a structural unit are more preferably used in the hair dye composition of the present invention.

Proanthocyanidins are apples, grapes,
It can be obtained by extraction and purification from various plants such as oysters, areca, barley, sacred grass, rhubarb, cinnamon bark, adzuki bean, and raspberry, and can also be obtained by chemical synthesis.

Extraction and purification from plants can be performed by the following known methods. After collecting the fruits, seeds, leaves, stems, roots, rhizomes, etc. of the raw materials of the plant at an appropriate time,
As it is or after performing a drying process such as natural air drying,
Use as an extraction material. If the raw material is plant juice or sap,
It can be used as it is as an extraction raw material.

The extraction of proanthocyanidins from the dried plant can be performed by referring to a known method. After pulverizing or shredding the raw material, the extraction can be performed by a batch or continuous extraction method using a solvent. As the extraction solvent, water or ethanol, methanol, alcohols such as isopropyl alcohol, acetone, ketones such as methyl ethyl ketone, methyl acetate,
A hydrophilic or lipophilic solvent such as an ester such as ethyl acetate can be used alone or as a mixed solvent. The extraction temperature is usually 0 to 100 ° C, preferably 5 to 50 ° C.
Perform at ° C.

From the crude extract obtained by the above operation, insoluble residue is removed by filtration or centrifugation, and proanthocyanidin is purified from the extract. The purification method is
Any known methods for separating and purifying crude drugs may be used,
It is preferable to use a two-phase solvent distribution method, a column chromatography method, a preparative high performance liquid chromatography method, or the like, alone or in combination.

By the above purification method, proanthocyanidins can be obtained as a result of removing water-soluble ionic substances such as salts, nonionic substances such as saccharides and polysaccharides, oils, pigments, etc. from the crude extract.

As a method for producing proanthocyanidins by a synthesis method, a method for producing a dimer of epicatechin or catechin is described in Journal of Chemical Society Parkin Transaction 1, 1535-154.
3, page 1983, and can be synthesized according to the methods described in these documents.

When proanthocyanidins are used in the present invention, one or more proanthocyanidins may be mixed. Specific examples include APC40 (product name, manufactured by Kyowa Hakko Kogyo Co., Ltd.).

In the hair dye composition of the present invention, the use of the proanthocyanidin in the hair dye composition (hair dye, shampoo, rinse, hair styling, hair restorer, etc.) and the dosage form (solution, dispersion, emulsion, (Paste, foam, etc.), preferably from 0.01 to 30% by weight of the total amount of the composition.
It is more preferable to mix so as to be 1 to 10% by weight, and it is particularly preferable to mix it at 0.5 to 10% by weight.

As mentioned above, proanthocyanidins are:
It exerts its hair dyeing effect under mild conditions by itself, but in order to further improve the hair dyeing effect, it reacts with a polyvalent metal salt such as ferrous sulfide on hair under mild conditions to dye hair. Is preferred. In this case, the polyvalent metal salt may or may not be contained in the hair dye composition of the present invention. That is, when the hair dye composition does not contain the polyvalent metal salt, the hair dye is supplied with the polyvalent metal salt from outside the hair dye composition when the hair is dyed.

Examples of such polyvalent metal salts include ferrous sulfate, ferric sulfate, ferrous chloride, ferric chloride, ferrous acetate, ferric acetate, ferrous nitrate, and nitric acid. Ferric, ferrous citrate, ferrous ammonium citrate, ferrous oxalate, ferrous carbonate, ferrous hydroxide, ferric hydroxide, ferrous phosphate,
Iron salts such as ferric phosphate, ferrous pyrophosphate, potassium ferrocyanide, and potassium ferricyanide; zinc salts such as zinc chloride, zinc nitrate, zinc sulfate, zinc hydroxide, and zinc acetate;
Lead salts such as lead acetate, lead sulfate, lead nitrate, lead chloride and copper sulfate,
Copper salts such as copper hydroxide and copper chloride; and polyvalent metal salts such as silver, bismuth, magnesium, tin and aluminum; iron salts, particularly ferrous chloride, ferric chloride, ferrous sulfate, and sulfuric acid It is preferable to use ferric iron or the like. The amount of such a polyvalent metal salt depends on the use and dosage form of the hair dye composition, but is preferably 0.01 to 20% by weight in the hair dye composition.

The hair dye composition of the present invention may further contain other components that are usually used in hair cosmetics, depending on the purpose of use, as long as the effects of the present invention are not impaired.

Ethanol and the like can be cited as components for improving the solubility of proanthocyanidins.

Examples of the thickener include xanthan gum, carboxymethyl cellulose, ethyl cellulose,
Hydroxyethylcellulose, hydroxypropylcellulose, carrageenan, alginate, pectin, ferrase, arabic gum, gatch gum, karaya gum, tragacanth gum, agar powder, bentonite, starch,
Crosslinked polyacrylic acid, polyvinyl alcohol and the like can be mentioned.

Examples of the humectant include glycerin, diglycerin, propylene glycol, dipropylene glycol, polyethylene glycol, 1,3-butylene glycol, chondroitin sulfate, hyaluronate, sorbitol, and pyrrolidone carboxylic acid.

Examples of the oil component include lanolin, squalane, liquid paraffin, petrolatum, higher fatty acids, higher alcohols, triglycerides, ester oils, etc., dimethylsiloxane, methylphenylsiloxane, polyoxyethylene / methylpolysiloxane copolymer, Silicones such as rubbery dimethylpolysiloxane and amino-modified polysiloxane are exemplified.

Examples of the nonionic surfactant include polyoxyethylene alkyl ether, polyoxyethylene hydrogenated castor oil derivative, polyoxyethylene fatty acid ester, polyoxyethylene polyhydric alcohol fatty acid partial ester, and polyoxyethylene alkyl phenyl ether. Polyoxyethylene surfactants, octyl glucoside, octyl polyglucoside, isostearyl glucoside, isostearyl maltoside, alkyl polyglucosides such as isostearyl polyglucoside, polyglycerin fatty acid ester, polyglycerin based polyglycerin alkyl ether and the like Surfactants, sugar alcohol ethers such as maltitol hydroxyalkyl ether and sorbitol alkyl ether, and fatty acid diethanolamide.

Examples of the anionic surfactant include, for example,
Higher fatty acid salts, polyoxyethylene alkyl sulfates,
Alkyl sulfate, alkyl benzene sulfonate, alkyl phosphate and the like can be mentioned.

Examples of the cationic surfactant include:
Examples thereof include an alkyltrimethylammonium salt, a dialkyldimethylammonium salt, and an alkyldimethylamine oxide.

Examples of the amphoteric surfactant include imidazoyl betaine, dimethylalkaloyl lysine and the like. Other surfactants can be used as appropriate.

Examples of the antioxidant include thioglycolate, L-ascorbate, bisulfite, hydrosulfite, sulfite, gallic acid, propyl gallate, butylhydroxyanisole, erythorbic acid and the like. Can be

Examples of sequestering agents and preservatives include hydroxyethanesulfonic acids, phenacetin,
EDTA and its salts, parabens, hinokitiol, stannates and the like can be mentioned.

Other components include a penetration enhancer such as benzyl alcohol and benzyloxyethanol, a feel enhancer such as a cationic polymer, a pH adjuster such as sodium citrate and sodium hydroxide, an ultraviolet absorber, a liquefied petroleum gas, and dimethyl ether. Propellants, such as herb extract, garlic extract, carrot extract, aloe extract, etc., fresheners such as pepper tincture, l-menthol, anti-inflammatory agents such as dipotassium glycyrrhizinate, allantoin, vitamins, pigments, flavors, purification Water and the like can be appropriately blended.

The hair dye composition of the present invention can be made into various dosage forms such as liquid, gel, air foam, cream and the like.

The hair dye composition of the present invention can be applied to hair by a known use method depending on the form of use. For example, when used as a hair restorer, the proanthocyanidin which is the hair dye component of the present invention adheres to both the hair and the hair by a simple operation of simply adapting the hair restorer to the scalp,
A hair dyeing effect can be obtained.

The hair dye composition of the present invention is highly safe for the human body, and can gradually exert a hair dyeing effect by a simple method of use.

[0039]

EXAMPLES Hereinafter, the hair dye composition of the present invention will be specifically described based on examples, but the present invention is not limited to these examples. In addition, APC40 [product name, manufactured by Kyowa Hakko Kogyo Co., Ltd.] was used as the proanthocyanidins in the examples.

Example 1 An aqueous solution containing APC40, 2.0% by mass was prepared. When the hair bundle (white hair 100%) was repeatedly immersed in the obtained aqueous solution, the gray hair was gradually dyed into a light natural black hair color.

Example 2 The components having the composition shown in Table 1 were uniformly mixed to produce a hair restorer containing proanthocyanidins.

[0042]

[Table 1] When the obtained hair restorer was repeatedly used on the scalp on a daily basis in a usual manner, the hair restorer adhered to the hair and gradually grayed the hair.

Example 3 A two-part hair dye comprising a first agent containing proanthocyanidin shown in Table 2 and a second agent containing a polyvalent metal salt shown in Table 3 was produced.

[0044]

[Table 2]

[0045]

[Table 3] 1 g of the obtained first agent was used to treat 1 g of a hair bundle (100% of white hair) at room temperature for 15 minutes, then treated with 1 g of the second agent for 15 minutes, thoroughly washed with tap water, and air-dried. When this operation was repeated five times, the white hair was dyed a natural black hair color. The same operation was performed using the above-mentioned first agent except for proanthocyanidins and the same second agent as described above, but the color of gray hair did not change.

[0046]

According to the hair dye composition of the present invention, hair can be dyed safely and under mild conditions. Moreover, the hair can be gradually dyed by a simple operation.

 ──────────────────────────────────────────────────続 き Continued on the front page (72) Inventor Shinkichi Honda 1-6-1 Otemachi, Chiyoda-ku, Tokyo Kyowa Hakko Kogyo Co., Ltd. (72) Inventor Tomoya Takahashi 2 Miyukigaoka, Tsukuba, Ibaraki Prefecture Address Kyowa Hakko Kogyo Co., Ltd. Tsukuba Research Laboratories F term (reference) 4C083 AA112 AB032 AB052 AB211 AB232 AB352 AC102 AC122 AC302 AC841 AC842 AD011 AD012 BB53 CC36 EE26 4J002 AJ001 DD076 DE096 DE106 DE116 DE246 DF026 DF036 FD0 630 EG046 FD056 GB00 HA05 HA08

Claims (3)

[Claims] 1. A hair dye composition comprising a polymer containing a flavan-7-ol or a derivative thereof as an essential constituent monomer. 2. The hair dye composition according to claim 1, wherein the polymer containing a flavan-7-ol or a derivative thereof as an essential constituent monomer is proanthocyanidin. 3. The hair dyeing composition according to claim 1, which comprises a polyvalent metal salt.