JPH0971519A - Skin lightening cosmetic - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a skin lightening cosmetic by adding an extract of a specific fruit to a system comprising a hydroquinone derivative, a pyrone and an extract of placenta, having highly inhibitory effect on melanogenesis, lightening and bleaching effect on melanin and anti-inflammatory effect. SOLUTION: This skin lightening cosmetic is obtained by combining one or more selected from a hydroquinone derivative, a pyrone such as kojic acid and an extract of placenta such as placenta essence, etc., with an extract of a fruit of Pyracantha fortu-neana, SEKISOU in Chinese, a kind of Rosaceae Pyreacantha. The content of the hydroquinone derivative, a pyrone and the placenta is about 0.01-30wt.%. The active ingredient of the fruit of Pyracantha fortu-neana, SEKIYOUSHI as Chinese medicine name is extracted with water or a lower alcohol such as methanol, its mixed solution and the extracted solution is used as it is but preferably powdered and used. The amount of the fruit is about 0.001-5wt.% calculated as the extract. The cosmetic is not mixed with a large amount of a hydroquinone derivative and is capable of rapidly lightening dark skin.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The technical field to which the present invention pertains is
It is a whitening cosmetic having an effect of promptly lightening dark skin.

[0002]

2. Description of the Related Art Conventionally, whitening cosmetics for the purpose of preventing or treating skin spots and freckles include L-ascorbic acid and its derivatives,
It contains hydroquinone derivatives, pyrones such as kojic acid, and placental extracts such as placenta extract.

These are widely known as substances having a whitening effect, with the effects of suppressing the production of melanin, light-color bleaching action of the produced melanin, and the like. But these are
For example, L-ascorbic acid and its derivatives are often insufficient in storage stability or have insufficient anti-inflammatory effects due to ultraviolet rays. Further, the hydroquinone derivative has problems such as insufficient safety. As described above, it is difficult to obtain a whitening cosmetic composition which is comprehensively excellent in the effect of suppressing the production of melanin, the light-color bleaching action of melanin, the effect of preventing inflammation, and the safety.

The Chinese name "Fire thorn" is known as a Chinese medicine name "Red Proton" for its fruit, and it is known to have medicinal effects such as keeping the spleen healthy and treating indigestion. Further, the fruit has a tyrosinase activity inhibitory effect and a melanin production inhibitory effect, and a whitening cosmetic composition containing this extract has been proposed (JP-A-5-55870). However, even when it was used alone, the whitening effect was not satisfactory.

As a result of intensive studies, the present inventors have found that one or more selected from hydroquinone derivatives, pyrones, and placenta extracts and fruits of the Chinese name "Fire spine" which is a member of the genus Pyracanta of the family Rosaceae. It has been found that a cosmetic containing a solvent extract has a high melanin production-inhibiting effect, a light-color bleaching effect of melanin, and an anti-inflammatory effect. Further, they have found that these synergistic effects are remarkably excellent in total, such that a satisfactory effect can be obtained without adding a large amount of hydroquinone derivative, and the present invention has been completed.

[0006] An object of the present invention is to provide a whitening cosmetic having an effect of rapidly lightening dark skin.

[0007]

Means for Solving the Problems The present invention that achieves the above-mentioned object is one or more selected from hydroquinone derivatives, pyrones, and placenta extracts, and a Chinese name “fire” which is one of the genus Pyracanta of the family Rosaceae. It is a whitening cosmetic containing a solvent extract of the fruit of "Thorn".

[0008]

BEST MODE FOR CARRYING OUT THE INVENTION An embodiment of the present invention is a whitening cosmetic composition.

The structure of the present invention will be described in detail below. Examples of the hydroquinone derivative used in the present invention include condensates of hydroquinone and sugar, and hydroquinone having 1 to 1 carbon atoms.
There is a condensate of alkylhydroquinone and sugar in which one alkyl group of 4 is introduced, such as arbutin.

Examples of the pyrones include kojic acid and meconic acid, and examples of the placenta extract include water-soluble placenta extract.

These hydroquinone derivatives, pyrones, and placenta extracts are blended in one kind or two or more kinds. Its content is 0.0 based on the total amount of prescription ingredients of cosmetics.
1 to 30% by weight is preferable, but not limited to this.

The active ingredient (hereinafter abbreviated as "fire thorn extract") of the Chinese medicine name "red proton" which is a fruit of Chinese name "fire thorn" used in the present invention is water or methanol, ethanol, propanol and the like. It is extracted with a lower alcohol or a mixed solution thereof. The extract can be blended into cosmetics as it is, but it is preferable to use it by pulverizing it by a freeze-drying method or a spray-drying method. It is also possible to mix the liquid or powdered product by purifying the extract liquid by means of liquid-liquid distribution, adsorption chromatography or the like.

It is preferable that the blending amount thereof is 0.001 to 5% by weight in terms of extract in the total amount of the cosmetic, but it is not limited to this.

In the cosmetics of the present invention, in addition to the above-mentioned raw materials, dyes, fragrances, preservatives, surfactants, pigments, antioxidants, humectants, ultraviolet absorbers and the like are included in the range to achieve the object of the present invention. It can be blended appropriately.

The dosage form of the cosmetic of the present invention includes creams, emulsions, lotions, packs and the like. For example, in the case of an emulsion or the like, this cosmetic can be produced by an ordinary method of emulsifying and dispersing an oily phase and an aqueous phase, which are dissolved by heating, and cooling.

[0016]

EXAMPLES The present invention will be described in detail below based on examples and comparative examples. The percentages shown in the examples are percentages by weight. The skin color lightness recovery test method, ultraviolet erythema suppression test method, and sensory evaluation test described in the examples are as follows. The method for preparing the fire thorn extract used in the following examples is as follows, but the scope of the present invention is not limited to these.

(Method for preparing fire thorn extract) 5.00 g of dried fruits of fire thorn are immersed in 50 ml of hot water at 90 ° C., boiled for 3 hours and then filtered, and the obtained extract is Diaion HP-
20 (Mitsubishi Chemical Industries Co., Ltd.) column (φ3 cm × 1)
1 cm, Vt = 80 ml), then 800 ml of 10
% Aqueous solution of ethanol. Then, it was eluted with 400 ml of 40% aqueous ethanol solution, the eluate was concentrated under reduced pressure, and then freeze-dried to obtain 1.04 g of a solid matter.

(1) Skin color lightness recovery test method The back skin of 20 subjects was irradiated with ultraviolet rays in the UV-B region at twice the minimum erythema dose, and a sample application site and a non-application site were set to determine the skin of each skin. The standard brightness (V0 value, V0 'value) was measured. Subsequently, the sample was applied to the application site twice a day for 15 times.
After continuous application for three weeks, the lightness (Vn value, Vn ') of the skin at the application site and the non-application site after 3, 6, 9, 12, and 15 weeks
Was measured, and the recovery of skin color was evaluated according to the following criteria. The lightness of the skin (Munsell color system V value)
Was calculated from the X, Y, and Z values obtained by measuring with a high-speed spectral colorimeter. The evaluation was shown by the average value of the evaluation points of 20 subjects after 3 weeks and 6 weeks.

(2) UV Erythema Suppression Test A region of 4 × 4 cm 2 was set on the back of the subject and 40 m
g sample was applied. This site was irradiated with sunlight for 1 hour, and the skin condition 24 hours after irradiation was visually observed. The erythema of the skin was determined according to the following criteria, and the average value of the evaluation points of 20 subjects was shown. (3) Sensory evaluation test Twenty-five subjects suffering from pigmentation evaluated the whitening effect by continuously using the sample for 3 weeks. The results are shown by the number of subjects who answered that there was a whitening effect.

Examples 1 to 4 and Comparative Examples 1 to 4 One or more kinds selected from hydroquinone derivatives, pyrones and placenta extracts and fire thorn extract were mixed in the composition shown in Table 1, and the following preparations were made. A skin cream was prepared based on the method. The above test was performed for each, and the results are shown in Table 3.

[0021]

[Table 1]

[0022]

[Table 2]

[0023]

[Table 3]

Preparation Method (A) is uniformly dissolved at 70 ° C. and B at 50 ° C. to prepare (A)
After stirring (B) into (A) while stirring to emulsify and disperse, the mixture is cooled to 30 ° C. while stirring to prepare.

Properties The skin creams of Examples 1 to 4 of the present invention were found to have a sufficient whitening effect. On the other hand, the skin creams of Comparative Examples 1 to 4 did not show a sufficient effect, and were inferior to the Examples of the present invention.

Example 5 A skin lotion of the present invention having the composition shown in Table 4 was prepared by the following production method.

[0027]

[Table 4]

Preparation Method (A), (B) Each component is mixed and dissolved, and (B)
Was added to (A) and mixed and stirred to prepare.

Properties The skin lotion of Example 5 showed a sufficient whitening effect 3 weeks after the start of the test.

Example 6 A day essence (daytime beauty essence) of the present invention having the composition shown in Table 5 was prepared by the following method.

[0031]

[Table 5] *, **: UV absorber manufactured by Givaudan

Preparation Method (A) is mixed at 70 ° C. and (B) at 50 ° C. to dissolve each component, and (B) is added to (A), and the mixture is stirred.
Prepared by cooling to ° C.

Characteristics The deessence of Example 6 showed a sufficient whitening effect 3 weeks after the start of the test.

[0034]

As described above, it is apparent that the present invention provides a whitening cosmetic having an effect of rapidly lightening dark skin.

Claims (1)

[Claims] 1. One or more selected from hydroquinone derivatives, pyrones, and placenta extracts, and the genus Rosaceae Pyraca-ntha.
Is a kind of Chinese name "Pyracantha"
A whitening cosmetic containing a solvent extract of the fruit of fortu-neana).