JPH09503913A - ヒト代謝向性グルタミン酸受容体サブタイプ（ｈｍｒ４，ｈｍｒ６，ｈｍｒ７）および関連ｄｎａ化合物 - Google Patents

ヒト代謝向性グルタミン酸受容体サブタイプ（ｈｍｒ４，ｈｍｒ６，ｈｍｒ７）および関連ｄｎａ化合物

Info

Publication number
JPH09503913A
JPH09503913A JP7509529A JP50952995A JPH09503913A JP H09503913 A JPH09503913 A JP H09503913A JP 7509529 A JP7509529 A JP 7509529A JP 50952995 A JP50952995 A JP 50952995A JP H09503913 A JPH09503913 A JP H09503913A
Authority
JP
Japan
Prior art keywords
hmglur
receptor
dna
subtype
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7509529A
Other languages
English (en)
Japanese (ja)
Inventor
ヨーゼフ フロール，ペーター
クーン，ライナー
リンダウアー，クリスティン
ピートナー，イレーネ
クヌーフェル，トマス
Original Assignee
チバ−ガイギー アクチェンゲゼルシャフト
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26134839&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPH09503913(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB9416553A external-priority patent/GB9416553D0/en
Application filed by チバ−ガイギー アクチェンゲゼルシャフト filed Critical チバ−ガイギー アクチェンゲゼルシャフト
Publication of JPH09503913A publication Critical patent/JPH09503913A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/286—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against neuromediator receptors, e.g. serotonin receptor, dopamine receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP7509529A 1993-09-20 1994-09-07 ヒト代謝向性グルタミン酸受容体サブタイプ（ｈｍｒ４，ｈｍｒ６，ｈｍｒ７）および関連ｄｎａ化合物 Pending JPH09503913A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP93810663 1993-09-20
GB93810663.0 1994-08-19
GB9416553A GB9416553D0 (en) 1993-09-20 1994-08-19 Novel receptor proteins
GB9416553.7 1994-08-19
PCT/EP1994/002991 WO1995008627A1 (en) 1993-09-20 1994-09-07 Human metabotropic glutamate receptor subtypes (hmr4, hmr6, hmr7) and related dna compounds

Publications (1)

Publication Number Publication Date
JPH09503913A true JPH09503913A (ja) 1997-04-22

Family

ID=26134839

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7509529A Pending JPH09503913A (ja) 1993-09-20 1994-09-07 ヒト代謝向性グルタミン酸受容体サブタイプ（ｈｍｒ４，ｈｍｒ６，ｈｍｒ７）および関連ｄｎａ化合物

Country Status (12)

Country Link
US (3) US6228610B1 (de)
EP (2) EP1199359B1 (de)
JP (1) JPH09503913A (de)
AT (2) ATE283916T1 (de)
AU (1) AU695641B2 (de)
CA (1) CA2171206A1 (de)
DE (1) DE69434166T2 (de)
FI (1) FI961251A0 (de)
HU (1) HUT74247A (de)
NO (1) NO961115L (de)
NZ (1) NZ273015A (de)
WO (1) WO1995008627A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010527921A (ja) * 2007-05-15 2010-08-19 エフ．ホフマン−ラ ロシュ アーゲー Ｇタンパク質共役受容体（ｇｐｃｒ）に対する抗体

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US5912122A (en) * 1993-06-04 1999-06-15 Sibia Neurosciences, Inc. Nucleic acids encoding and method for detecting nucleic acid encoding human metabotropic glutamate receptor subtype mGluR6
US6274330B1 (en) 1993-12-30 2001-08-14 Zymogenetics, Inc. L-AP4 sensitive glutamate receptors
WO1995022609A2 (en) * 1994-02-21 1995-08-24 The Wellcome Foundation Limited Human glutamate receptor proteins
IL120424A0 (en) * 1995-07-26 1997-07-13 Nps Pharma Inc Chimeric receptors and methods for identifying compounds active at metabotropic glutamate receptors and the use of such compounds in the treatment of neurological disorders and diseases
US6084084A (en) * 1996-02-21 2000-07-04 Nps Pharmaceuticals, Inc. Human metabotropic glutamate receptor
US6384205B1 (en) * 1996-03-12 2002-05-07 Eli Lilly And Company Metabotropic glutamate receptor 4 nucleic acid
US6221609B1 (en) * 1996-07-03 2001-04-24 Eli Lilly And Company Isolate nucleic acid encoding human MGLUR8
WO1998011242A2 (en) 1996-09-13 1998-03-19 Novartis Ag Neurological disease model
US6248542B1 (en) * 1997-12-09 2001-06-19 Massachusetts Institute Of Technology Optoelectronic sensor
US7262280B1 (en) 1998-04-03 2007-08-28 Nps Pharmaceuticals, Inc. G-protein fusion receptors and constructs encoding same
US6103524A (en) * 1998-07-30 2000-08-15 Eli Lilly And Company Metabotropic glutamate receptor protein and nucleic acid
TW201006846A (en) 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
TW201022287A (en) * 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
US7422860B2 (en) 2001-02-07 2008-09-09 Massachusetts Institute Of Technology Optoelectronic detection system
US8216797B2 (en) * 2001-02-07 2012-07-10 Massachusetts Institute Of Technology Pathogen detection biosensor
DE60216051T2 (de) 2001-02-07 2007-06-28 Massachusetts Institute Of Technology, Cambridge Optoelektronisches nachweissystem
US7368285B2 (en) 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
US7301009B2 (en) 2001-06-26 2007-11-27 Senomyx, Inc. Isolated (T1R1/T1R3) umami taste receptors that respond to umami taste stimuli
US20080244761A1 (en) 2001-03-07 2008-10-02 Senomyx, Inc. T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
EP1412750B1 (de) 2001-06-26 2012-05-23 Senomyx, Inc. Heterooligomere t1r2-t1r3 Süssegeschmacksrezeptoren und diese exprimierende Zellinien sowie Verwendung davon zur Identifizierung von Süssegeschmacksverbindungen
DK2327985T3 (en) 2001-06-26 2016-09-05 Senomyx Inc H1 Oligomeric T1R Taste Receptors and Cell Lines Expressing the Receptors, and Their Use to Identify Taste Compounds
WO2003014696A2 (en) * 2001-08-06 2003-02-20 Stil Biotechnologies Ltd. Methods of identifying functional analogs of peptide regulators of biological pathways
EP1467661A4 (de) * 2001-12-19 2008-11-05 Nmt Medical Inc Septumverschlusseinrichtung und zugehörige verfahren
CA2517027A1 (en) 2002-02-25 2003-09-04 Vaxiion Therapeutics, Inc. Minicell compositions and methods
AU2003240549A1 (en) * 2002-06-05 2003-12-22 Nmt Medical, Inc. Patent foramen ovale (pfo) closure device with radial and circumferential support
US7766820B2 (en) * 2002-10-25 2010-08-03 Nmt Medical, Inc. Expandable sheath tubing
EP2399526B1 (de) 2002-12-09 2014-11-26 W.L. Gore & Associates, Inc. Septumverschlussvorrichtungen
US8480706B2 (en) 2003-07-14 2013-07-09 W.L. Gore & Associates, Inc. Tubular patent foramen ovale (PFO) closure device with catch system
US7678123B2 (en) 2003-07-14 2010-03-16 Nmt Medical, Inc. Tubular patent foramen ovale (PFO) closure device with catch system
US9861346B2 (en) 2003-07-14 2018-01-09 W. L. Gore & Associates, Inc. Patent foramen ovale (PFO) closure device with linearly elongating petals
US20050186658A1 (en) * 2003-10-17 2005-08-25 Nps Pharmaceuticals, Inc. Chimeric metabotropic glutamate receptors and uses thereof
WO2005075988A1 (en) * 2004-01-28 2005-08-18 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with human metabotropic glutamate receptor 7 (mglur7)
US7842053B2 (en) * 2004-05-06 2010-11-30 Nmt Medical, Inc. Double coil occluder
US8257389B2 (en) 2004-05-07 2012-09-04 W.L. Gore & Associates, Inc. Catching mechanisms for tubular septal occluder
DE102004026744A1 (de) * 2004-05-28 2005-12-29 Philipps-Universität Marburg Erfindung betreffend cDNA-Herstellung aus Zellen nach Laser-Mikrodissektion
WO2006102213A1 (en) 2005-03-18 2006-09-28 Nmt Medical, Inc. Catch member for pfo occluder
US8870913B2 (en) 2006-03-31 2014-10-28 W.L. Gore & Associates, Inc. Catch system with locking cap for patent foramen ovale (PFO) occluder
US9005242B2 (en) 2007-04-05 2015-04-14 W.L. Gore & Associates, Inc. Septal closure device with centering mechanism
US20130165967A1 (en) 2008-03-07 2013-06-27 W.L. Gore & Associates, Inc. Heart occlusion devices
US20120029556A1 (en) 2009-06-22 2012-02-02 Masters Steven J Sealing device and delivery system
US8956389B2 (en) 2009-06-22 2015-02-17 W. L. Gore & Associates, Inc. Sealing device and delivery system
US9770232B2 (en) 2011-08-12 2017-09-26 W. L. Gore & Associates, Inc. Heart occlusion devices
US10828019B2 (en) 2013-01-18 2020-11-10 W.L. Gore & Associates, Inc. Sealing device and delivery system
US9804157B1 (en) 2013-03-15 2017-10-31 Senomyx, Inc. Screening assays to identify compounds which modulate T1R associated taste modalities which eliminate false positives
US9808230B2 (en) 2014-06-06 2017-11-07 W. L. Gore & Associates, Inc. Sealing device and delivery system
KR20180050321A (ko) 2015-08-07 2018-05-14 이미지냅 인코포레이티드 분자를 표적화하기 위한 항원 결합 구조체
US11266745B2 (en) 2017-02-08 2022-03-08 Imaginab, Inc. Extension sequences for diabodies

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US3829583A (en) * 1971-02-20 1974-08-13 Hayashibara Ken Mixture of maltobionic acid and monosodium glutamate as a food seasoning
AU652349B2 (en) * 1989-10-27 1994-08-25 Salk Institute For Biological Studies, The Glutamate receptor compositions and methods
US5385831A (en) 1990-12-12 1995-01-31 Zymogenetics, Inc. Method for producing a mammalian G protein coupled glutamate receptor
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IL105587A0 (en) 1992-05-08 1993-09-22 Lilly Co Eli Human metabotropic glutamate receptor and related dna compounds
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US5521297A (en) * 1993-06-04 1996-05-28 Salk Institute Biotechnology/Industrial Associates Nucleic acids encoding human metabotropic glutamate receptors
US6274330B1 (en) * 1993-12-30 2001-08-14 Zymogenetics, Inc. L-AP4 sensitive glutamate receptors
WO1995022609A2 (en) * 1994-02-21 1995-08-24 The Wellcome Foundation Limited Human glutamate receptor proteins
GB9416554D0 (en) 1994-08-19 1994-10-12 Ciba Geigy Ag Glutamate receptor
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010527921A (ja) * 2007-05-15 2010-08-19 エフ．ホフマン−ラ ロシュ アーゲー Ｇタンパク質共役受容体（ｇｐｃｒ）に対する抗体

Also Published As

Publication number Publication date
HUT74247A (en) 1996-11-28
FI961251A (fi) 1996-03-18
EP0720650A1 (de) 1996-07-10
ATE283916T1 (de) 2004-12-15
ATE522610T1 (de) 2011-09-15
FI961251A0 (fi) 1996-03-18
DE69434166T2 (de) 2005-11-10
HU9600692D0 (en) 1996-05-28
US6515107B2 (en) 2003-02-04
DE69434166D1 (de) 2005-01-05
US20020127638A1 (en) 2002-09-12
WO1995008627A1 (en) 1995-03-30
EP0720650B1 (de) 2004-12-01
NO961115D0 (no) 1996-03-19
AU7615994A (en) 1995-04-10
NZ273015A (en) 1997-09-22
CA2171206A1 (en) 1995-03-30
NO961115L (no) 1996-03-19
US20030113868A1 (en) 2003-06-19
US7253257B2 (en) 2007-08-07
EP1199359B1 (de) 2011-08-31
AU695641B2 (en) 1998-08-20
EP1199359A1 (de) 2002-04-24
US6228610B1 (en) 2001-05-08

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