JPH0899847A - Composition for oral cavity - Google Patents

Abstract

PURPOSE: To obtain a composition for oral cavity which comprises a combination of table salt, baking powder and a specific bitter substance, thus masks the salt taste remaining as an aftertaste to leave a pleasant aftertaste. CONSTITUTION: This composition comprises (A) table salt (sodium chloride) (preferably of 200-300μm average particle size), (B) baking powder (sodium bicarbonate) of 200-300μm average particle size and (C) a chain terpenic alcohol or its derivative, for example, linalol, geraniol or the like. It is preferred that the content of component A is 15-20wt.%; component B, 10-30wt.%; the weight ratio of A/B is l/1.1-1/2. The content of the component C is preferably 0.001-0.1wt.%. After they are formulated together with oral vehicles in an ordinary manner, the composition is made into preparations such as tooth paste or the like.

Description

Detailed Description of the Invention

[0001]

FIELD OF THE INVENTION The present invention relates to an oral composition, and more particularly to an oral composition containing salt and baking soda having an improved aftertaste.

[0002]

2. Description of the Related Art Toothpastes containing sodium chloride or sodium bicarbonate as a medicinal agent or for improving the taste and feel of toothpastes are commercially available. However, when baking soda is added to the toothpaste, the aftertaste is deteriorated. Especially, when baking soda is added to the salt-containing toothpaste, the salt-derived ene taste remains in the aftertaste, which is a problem in terms of palatability.

Accordingly, the object of the present invention is to provide a good aftertaste,
An object is to provide an oral composition containing salt and baking soda.

[0004]

Means for Solving the Problems As a result of intensive studies, the present inventors have achieved the above object by adding a specific bitter substance to mask the salt-derived ene taste remaining in the aftertaste by the bitter substance. It was discovered that it will be done.

The present invention has been made based on the above findings, and provides an oral composition containing the following components (a), (b) and (c). (A) Salt (b) Baking soda (c) Chain terpene alcohol or its derivative

The oral composition of the present invention will be described in detail below. The salt which is the component (a) of the oral composition of the present invention has an average particle size of 150 to 450 μm, preferably 1
50 to 350 μm, particularly preferably 150 to 300 μm
m, most preferably 200 to 300 μm of granular salt is preferably used. If the average particle size of the granular salt is less than 150 μm, the salt is rapidly dissolved in saliva in the oral cavity, and saltiness may be rapidly developed. Also,
If the average particle size of the granular salt is more than 450 μm, the feeling in the oral cavity is deteriorated, and in extreme cases, there is a risk of damaging soft tissues in the oral cavity such as gums.

The baking soda which is the component (b) of the oral composition of the present invention has an average particle size of 45 to 450 μm, preferably 100 to 300 μm, and particularly preferably 200 to.
It is preferable to use 300 μm granular baking soda. When the average particle size of the granular baking soda is less than 45 μm, the baking soda is rapidly dissolved in saliva in the oral cavity, and the time during which the granular salt can be sensed becomes short. Further, if the average particle size of the granular baking soda exceeds 450 μm, the feel may be deteriorated, and the baking soda may not be completely dissolved in saliva in the oral cavity within 2 minutes which is an average tooth brushing time. It will be spit out in vain without exhibiting.

The method of producing the above-mentioned granular baking soda is not particularly limited, but crystals precipitated by passing carbon dioxide in a pure sodium carbonate solution at 50 ° C. or lower are filtered off, dried in a carbon dioxide stream and pulverized. Those obtained by the production method are preferred.

Examples of the chain terpene alcohol or its derivative which is the component (c) of the oral composition of the present invention include linalool, linalyl acetate, geraniol, geranyl acetate, citronellol, and citronellyl acetate. One or two or more selected from these can be used.

The oral composition of the present invention contains the chain terpene alcohol or the derivative thereof, which is the above-mentioned component (c), in an amount of 0.
The content is preferably 0001 to 1% by weight, particularly 0.001 to 0.1% by weight. The content of the component (c) is 0.
If it is less than 0001% by weight, it is difficult to sufficiently mask the ene taste derived from salts, and if it is more than 1% by weight, the flavor derived from the component (c) becomes too strong, which is a problem from the viewpoint of palatability. Sometimes.

Further, the oral composition of the present invention has an appropriate taste of salt and exerts the maximum dehydrating effect.
The salt of the component (a) is 10% by weight or more, particularly 10 to 3
It is preferable to contain 0% by weight, more preferably 15 to 20% by weight. Further, the oral composition of the present invention preferably contains 3 to 50% by weight, and particularly 10 to 30% by weight of the baking soda as the component (b). Moreover, the composition for oral cavity of the present invention has a weight compounding ratio (salt / sodium bicarbonate) of sodium chloride as the component (a) and baking soda as the component (b) within a range of 1 / 0.5 to 1/3, Particularly within the range of 1 / 0.8 to 1/2, and further 1 / 1.1 to 1/2
It is preferably within the range.

In the oral composition of the present invention, as the salt as the component (a) and the baking soda as the component (b), granular salt having a particle size outside the range of 150 to 450 μm and a particle size of 4 are used.
Although it may contain granular baking soda outside the range of 5 to 450 μm, the content of granular salt having a particle size of less than 150 μm and the content of granular salt having a particle size of more than 450 μm are both 10% by weight or less. Preferably, the content of granular baking soda having a particle size of less than 45 μm is 50% by weight or less, particularly 20% by weight or less, and the content of granular baking soda having a particle size of more than 450 μm is 3%.
It is preferably 0% by weight or less, particularly preferably 15% by weight or less.

The oral composition of the present invention comprises the above-mentioned (a) common salt, (b) baking soda, and (c) chain terpene alcohol or a derivative thereof in an oral vehicle according to a conventional method, a toothpaste and a liquid. It is prepared by preparing a dosage form such as a dentifrice, a powdered dentifrice, a gingival application agent (pasta agent for oral cavity) and the like. When the oral composition of the present invention is used as a dentifrice, as the oral vehicle, a water-insoluble polishing agent, a binder, a wetting agent,
Surfactants, flavors, sweeteners, germicides, preservatives, pigments,
Water, water-soluble fluoride, silicone, other active ingredients and the like are used as appropriate.

The above water-insoluble abrasives include calcium hydrogen phosphate for toothpaste, heavy calcium carbonate, light calcium carbonate, calcium pyrophosphate, insoluble sodium metaphosphate, potassium metaphosphate, anhydrous silicic acid, hydrous silicic acid, and aluminum silicate. , Calcium silicate, zirconium silicate, bentonite, zeolite, aluminum oxide, aluminum hydroxide, alumina, resin and mixtures thereof. Of these, silicic acid anhydride, hydrous silicic acid, calcium silicate, aluminum silicate, heavy calcium carbonate, light calcium carbonate, aluminum hydroxide, alumina is particularly preferable for obtaining a dentifrice having good storage stability, Aluminum hydroxide is more preferable from the viewpoint that a better flavor stability can be obtained.

As the above-mentioned binder, sodium carboxymethyl cellulose, methyl cellulose, hydroxyethyl cellulose, alginate, carrageenan, gum arabic, polyvinyl alcohol, tragacanth gum,
Starch, sodium polyacrylate, etc. are mentioned.
The wetting agent is polyethylene glycol,
Propylene glycol, sorbitol, glycerin, maltitol, xylitol and the like can be mentioned. Of these, glycerin and sorbitol are particularly preferable.

The surface active agent is used as a foaming agent or a stabilizer for an oily substance, and various surface active agents are used. Examples of preferred surfactants include alkyl sulfates, alkylbenzene sulfonates,
Monoalkyl phosphate ester salt, N-acyl sarcosinate salt, N-acyl glutamate salt, polyoxyethylene hydrogenated castor oil, polyoxyethylene polyoxypropylene block copolymer (pluronic type), sucrose fatty acid ester, alkyl glycosides, Examples thereof include sorbitan fatty acid ester, polyoxyethylene sorbitan fatty acid ester, alkyldimethylamine oxide, carbobetaine, hydroxycarbobetaine, phosphobetaine, hydroxyphosphobetaine, sulfobetaine and hydroxysulfobetaine. Among these, water-soluble nonionic surfactants such as polyoxyethylene hydrogenated castor oil, polyoxyethylene polyoxypropylene block copolymer, sucrose fatty acid ester, alkyl glycosides, sorbitan fatty acid ester, polyoxyethylene sorbitan fatty acid ester and Amphoteric surfactants are especially preferred.

As the above-mentioned fragrance, spearmint oil, peppermint oil, winder green oil, sassafras oil, clove oil, sage oil, eucalyptus oil, mayonnaise oil,
Natural flavors such as cinnamon oil, thyme oil, lemon oil and orange oil; and synthetic flavors such as 1-menthol, anethole, carvone, eugenol, thymol and methyl salicylate. Further, as the sweetener, saccharin,
Examples thereof include sodium saccharin, stevioside, neohesperidyl dihydrochalcone, berlartine, p-methoxycinnamic aldehyde, glycyrrhizic acid salt, aspartame (aspartylphenylalanine methyl ester) and the like.

Examples of the bactericide include chlorhexidine salts, cetylpyridinium chloride, benzalkonium chloride, benzethonium chloride and the like. Examples of the preservatives include benzoic acid, sodium benzoate, parahydroxybenzoic acid, parahydroxybenzoic acid ester and the like.

Examples of the above water-soluble fluorides include sodium fluoride and sodium monofluorophosphate. Further, as the above-mentioned other active ingredients, chlorophyll compounds, ε-aminocaproic acid, tranexamic acid, vitamin C, vitamin E, nicotinic acid ester, allantoinchlorohydroxyaluminum, azulene,
Examples thereof include lysozyme chloride, hinokitiol, β-glycyrrhetinic acid, dipotassium glycyrrhizinate, protease, and herbal medicine extracts.

When the oral composition of the present invention is used as a paste-like dentifrice composition such as a toothpaste or a liquid dentifrice, all the components of the above-mentioned oral vehicle for dentifrice may be blended. However, basically, it is preferable that the oral vehicle contains 10 to 75% by weight of a water-insoluble abrasive, 0.5 to 5% by weight of a binder, 10 to 85% by weight of a wetting agent and water. preferable. Here, the content of the water-insoluble abrasive is preferably 20 to 75% by weight in the case of a toothpaste and 10 to 30% by weight in the case of a liquid dentifrice. Further, in the case of a solid composition such as a powder dentifrice, a solid component can be blended among the components of the oral vehicle for the above dentifrice, but basically, a water-insoluble abrasive in the oral vehicle is added. It is preferable to add 60 to 99% by weight. Further, it is preferable to add 0.01 to 5% by weight of the flavor and sweetener in the oral vehicle in total.

When the oral composition of the present invention is used as a gingival application agent, the oral vehicle may be an oily component or a water-soluble polymer, a wetting agent, a surfactant, a perfume, a sweetener, A bactericidal agent, an antiseptic agent, a pigment, water, a water-soluble fluoride, silicone, other active ingredients and the like are appropriately used.

Examples of the oily component include petroleum jelly, lanolin, liquid paraffin, natural fats and oils, higher fatty acid esters such as isopropyl myristate and octyldodecyl myristate, higher fatty acids such as palmitic acid and isostearic acid, myristyl alcohol, cetyl alcohol. And higher alcohols such as squalane, silicone oil and the like. Further, as the above water-soluble polymer, those exemplified as the above-mentioned binder can be used, and among these, bidroxyethyl cellulose is particularly preferable. Further, a water-soluble polymer such as polyethylene glycol or polyoxyethylene polyoxypropylene block copolymer can also be preferably used. The gingival coating agent preferably contains the oily component or the water-soluble polymer in an amount of 10 to 50% by weight, and a wetting agent and water in an amount of 20 to 70% by weight.

The pH of the oral composition of the present invention is
Is preferably in the range of 5 to 9.5, particularly 6 to 8.

[0024]

In the composition for oral cavity of the present invention, the chain terpene alcohol or the derivative thereof as the component (c) masks the tinged taste derived from salts which remains in the aftertaste, thereby improving the aftertaste.

[0025]

EXAMPLES The present invention will be described in detail below with reference to examples, but the present invention is not limited thereto. still,
The average particle diameters of the granular salt and the baking soda used in the examples are obtained by the following measuring method.

[Measurement Method of Average Particle Size of Granular Salt and Granular Baking Soda] 1) 50 g of the oral composition was placed in a 300 ml beaker of granular salt, and 5000 ml of saturated saline solution (100 times volume) was poured into the beaker and stirred with a homomixer. , Completely suspend the oral composition. Only about 1% of sodium bicarbonate is dissolved in saturated saline, but by dissolving it in a large excess amount of saturated saline, only sodium bicarbonate can be completely dissolved. Granular salt is recovered from the above suspension using a 200-mesh sieve (American standard sieve LC584), and washed with saturated saline and ethanol on the mesh. After leaving it in the electric dryer (100 ° C) for about 30 minutes,
After collecting the collected granular salt in a petri dish and measuring the weight, meshes of various sizes (35, 45, 60, 80, 120,
170, 230, 325 mesh), and the weight of the granular salt remaining on each sieve is measured. From this weight distribution, a geometric mean diameter is obtained and this is used as the mean particle diameter. 2) Granular baking soda 1) The measurement is performed in the same manner as in 1) except that saturated sodium bicarbonate water is used instead of saturated saline.

Examples 1 to 6 and Comparative Example 1 A toothpaste was prepared according to a conventional method with the compounding composition shown in the following [Table 1]. The aftertaste was evaluated for each of the obtained toothpastes. The results are shown in [Table 2] below.

[0028]

[Table 1]

[0029]

[Table 2]

Example 7 A toothpaste was prepared according to a conventional method according to the composition shown in Table 3 below. The resulting toothpaste had no odor and had a good aftertaste.

[0031]

[Table 3]

[0032]

EFFECTS OF THE INVENTION The oral composition of the present invention has a good aftertaste by masking the salt-derived enemy that remains in the aftertaste.

Claims (4)

[Claims] 1. A composition for oral cavity containing the following components (a), (b) and (c). (A) Salt (b) Baking soda (c) Chain terpene alcohol or its derivative 2. The average particle size of the component (a) is 150 to 45.
It is a 0 μm granular salt, and the component (b) has an average particle size of 4
The oral composition according to claim 1, which is granular baking soda having a particle size of 5 to 450 μm. 3. The component (c) is one or more selected from the group consisting of linalool, linalyl acetate, geraniol, geranyl acetate, citronellol, and citronellyl acetate. Oral composition. 4. The content of the component (c) is 0.0001.
The composition for oral cavity according to claim 1, which is ˜1% by weight.