JP3241946B2 - Oral composition - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an oral composition, and more particularly to an oral composition containing salt and baking soda having improved feeling in use (particularly powderiness).

[0002]

BACKGROUND OF THE INVENTION Toothpastes containing salt or baking soda as a medicinal agent or for improving the taste and feel of a toothpaste are commercially available. However, a toothpaste containing salt or baking soda has a powdery property caused by salt or baking soda, and there is a problem that the feeling of use is poor due to the powderiness.

[0003] Accordingly, an object of the present invention is to provide an oral composition containing salt and baking soda, which has an improved feeling of use with improved powderiness caused by salt and baking soda.

[0004]

Means for Solving the Problems As a result of intensive studies, the present inventors have found that the above object can be achieved by adding a specific substance.

[0005] The present invention has been made based on the above findings, and comprises the following components (a), (b) and (c), wherein the content of the component (a) is 10 to 30% by weight. so,
Weight ratio of component (a) to component (b) (salt / baking soda)
Is in the range of 1 / 0.5 to 1/3 . (A) Salt (b) Baking soda (c) Basil, camphor, caraway, cardamom, coriander, ginger, laurel, lavender, nutmeg, pepper, thyme, ylang-ylang, carrot seed, elemi, osmantas essential oil and extract, borneol And at least one member selected from the group consisting of and borneol derivatives

Hereinafter, the oral composition of the present invention will be described in detail. The salt which is the component (a) of the oral composition of the present invention has an average particle diameter of 150 to 450 μm, preferably 1 to 450 μm.
50 to 350 μm, particularly preferably 150 to 300 μm
It is preferred to use a granular salt of m, most preferably 200-300 μm. If the average particle size of the granular salt is less than 150 μm, the salt rapidly dissolves in saliva in the oral cavity, and saltiness may be rapidly developed. Also,
If the average particle size of the granular salt is more than 450 μm, the feeling in the oral cavity becomes poor, and in extreme cases, there is a concern that soft tissues in the oral cavity such as gums may be damaged.

The baking soda as the component (b) of the oral composition of the present invention has an average particle size of 45 to 450 μm, preferably 100 to 300 μm, and particularly preferably 200 to 300 μm.
It is preferable to use 300 μm granular sodium bicarbonate. If the average particle size of the particulate baking soda is less than 45 μm, baking soda is rapidly dissolved in saliva in the oral cavity, so that the time for palpating the granular salt is reduced. In addition, if the average particle size of the particulate baking soda is more than 450 μm, there is a concern that the feeling may be deteriorated, and the baking soda cannot be completely dissolved in saliva in the oral cavity within an average toothbrushing time of 2 minutes or less. And will be spit out needlessly.

The method for producing the above-mentioned granular sodium bicarbonate is not particularly limited, but crystals precipitated from pure sodium carbonate solution through carbon dioxide at 50 ° C. or lower are filtered off, dried in a stream of carbon dioxide and pulverized. The one obtained by the following production method is preferable.

The component (c) of the oral composition of the present invention comprises basil, camphor, caraway, cardamom,
Coriander, ginger, laurel, lavender, nutmeg, pepper, thyme, ylang-ylang, carrot seed, elemi, osmanthus essential oil and extract, borneol and borneol derivatives, and one or more selected from these are used. . Examples of the borneol derivative include isobornyl acetate, bornyl acetate, bornyl formatate, and bornyl propionate. As the above-mentioned component (c), camphor, laurel, thyme, carrot seed, essential oil and extract of Elemi, borneol, and isobornyl acetate are particularly preferable.

The oral composition of the present invention contains the component (c) in an amount of 0.000001 to 0.
It is preferably contained in an amount of 1% by weight, particularly 0.00001 to 0.01% by weight. The content of the component (c) is
0.0001 to 1 of the total fragrance in the oral composition of the present invention
It is preferably 0% by weight, especially 0.01 to 10% by weight.

[0011] The oral composition of the present invention is required to exhibit an appropriate salt taste and exhibit the maximum dehydration effect.
The salt of the component (a) is 10% by weight or more, especially 10 to 3%.
It is preferably contained in an amount of 0% by weight, more preferably 15 to 20% by weight. In addition, the oral composition of the present invention preferably contains 3 to 50% by weight, particularly 10 to 30% by weight of the above-mentioned component (b). Further, the oral composition of the present invention has a weight ratio of the salt of the component (a) to the sodium bicarbonate of the component (b) (salt / bicarbonate) within the range of 1 / 0.5 to 1/3. In particular, within the range of 1 / 0.8 to 1/2, and further 1/1/1/2.
Is preferably within the range.

The oral composition of the present invention contains, as the salt (a) and the sodium bicarbonate (b), a granular salt having a particle size outside the range of 150 to 450 μm and a particle size of 4%.
Granular sodium bicarbonate outside the range of 5 to 450 μm may be contained, but the content of granular salt having a particle size of less than 150 μm and the content of granular salt having a particle size of more than 450 μm are all 10% by weight or less. Preferably, the content of particulate baking soda having a particle size of less than 45 μm is 50% by weight or less, particularly 20% by weight or less, and the content of particulate baking soda having a particle size of more than 450 μm is 3%.
It is preferably 0% by weight or less, particularly preferably 15% by weight or less.

The oral composition of the present invention is prepared by mixing the above-mentioned components (a), (b) and (c) with an oral vehicle according to a conventional method, and using a toothpaste, a liquid dentifrice, a powder dentifrice, It is prepared in the form of a gingival coating (oral pasta). When the oral composition of the present invention is used as a dentifrice, as the oral vehicle, other than a water-insoluble abrasive,
Binders, wetting agents, surfactants, flavors, sweeteners, fungicides,
Preservatives, dyes, water, water-soluble fluorides, silicones, and other active ingredients are appropriately used.

The above water-insoluble abrasives include calcium hydrogen phosphate for toothpaste, heavy calcium carbonate, light calcium carbonate, calcium pyrophosphate, insoluble sodium metaphosphate, potassium metaphosphate, silicic anhydride, hydrous silicic acid, aluminum silicate , Calcium silicate, zirconium silicate, bentonite, zeolite, aluminum oxide, aluminum hydroxide, alumina, resin, and mixtures thereof. Among them, silicic anhydride, hydrous silicic acid, calcium silicate, aluminum silicate, heavy calcium carbonate, light calcium carbonate, aluminum hydroxide, and alumina are particularly preferable to obtain a dentifrice with good storage stability, Aluminum hydroxide is more preferred in that a better flavor stability can be obtained.

Examples of the binder include sodium carboxymethylcellulose, methylcellulose, hydroxyethylcellulose, alginate, carrageenan, gum arabic, polyvinyl alcohol, tragacanth gum,
Starch and sodium polyacrylate;
Further, as the wetting agent, polyethylene glycol,
Examples include propylene glycol, sorbitol, glycerin, maltitol, xylitol and the like. Of these, glycerin, sorbitol and the like are particularly preferred.

The surfactant is used as a foaming agent or a stabilizer for oily substances, and various surfactants are used. Examples of preferred surfactants include alkyl sulfates, alkyl benzene sulfonates,
Monoalkyl phosphate salts, N-acyl sarcosinates, N-acyl glutamates, polyoxyethylene hydrogenated castor oil, polyoxyethylene polyoxypropylene block copolymers (pluronic type), sucrose fatty acid esters, alkyl glycosides, Sorbitan fatty acid ester, polyoxyethylene sorbitan fatty acid ester, alkyldimethylamine oxide, carbobetaine, hydroxycarbobetaine, phosphobetaine, hydroxyphosphobetaine, sulfobetaine, hydroxysulfobetaine and the like. Among these, water-soluble nonionic surfactants such as polyoxyethylene hydrogenated castor oil, polyoxyethylene polyoxypropylene block copolymer, sucrose fatty acid ester, alkyl glycosides, sorbitan fatty acid ester, and polyoxyethylene sorbitan fatty acid ester; Amphoteric surfactants are particularly preferred.

Further, as the above-mentioned fragrance, spearmint oil, peppermint oil, winder green oil, sassafras oil, clove oil, sage oil, eucalyptus oil, mayonnaise oil,
Natural flavors such as cinnamon oil, lemon oil and orange oil; and 1
-Menthol, anethole, carvone, eugenol,
Synthetic fragrances such as thymol and methyl salicylate are exemplified. Examples of the sweetener include saccharin, saccharin sodium, stevioside, neohesperidyl dihydrochalcone, berlartine, p-methoxycinnamic aldehyde, glycyrrhizinate, aspartame (aspartylphenylalanine methyl ester) and the like.

The bactericide includes salts of chlorhexidine, cetylpyridinium chloride, benzalkonium chloride, benzethonium chloride and the like. Examples of the preservative include benzoic acid, sodium benzoate, parahydroxybenzoic acid, and parahydroxybenzoic acid ester.

Examples of the water-soluble fluoride include sodium fluoride and sodium monofluorophosphate. Further, as the other active ingredients, chlorophyll compounds, ε-aminocaproic acid, tranexamic acid, vitamin C, vitamin E, nicotinic acid ester, allantoinchlorohydroxyaluminum, azulene,
Examples include lysozyme chloride, hinokitiol, β-glycyrrhetinic acid, dipotassium glycyrrhizinate, protease, and crude drug extracts.

When the oral composition of the present invention is used as a paste-like dentifrice composition such as a toothpaste or a liquid dentifrice, all the components of the oral vehicle for a dentifrice may be blended. Basically, it is preferable that the oral vehicle contains 10 to 75% by weight of a water-insoluble abrasive, 0.5 to 5% by weight of a binder, and 10 to 85% by weight of a wetting agent and water. preferable. Here, the content of the water-insoluble abrasive is preferably 20 to 75% by weight for toothpaste and 10 to 30% by weight for liquid toothpaste. When a solid composition such as a powdered dentifrice is used, a solid component can be blended among the components of the oral vehicle for the dentifrice, but basically, a water-insoluble abrasive is contained in the oral vehicle. It is preferable to mix 60 to 99% by weight. In addition, it is preferable that the flavor and sweetener are incorporated in the oral vehicle in a total amount of 0.01 to 5% by weight.

In the case where the oral composition of the present invention is used as a gingival coating agent, the oral vehicle may include, in addition to an oily component or a water-soluble polymer, a wetting agent, a surfactant, a flavor, a sweetener, Disinfectants, preservatives, dyes, water, water-soluble fluorides, silicones, and other active ingredients are appropriately used.

Examples of the oily component include petrolatum, lanolin, liquid paraffin, natural fats and oils, higher fatty acid esters such as isopropyl myristate and octyldodecyl myristate, higher fatty acids such as palmitic acid and isostearic acid, myristyl alcohol and cetyl alcohol. And the like, squalane, silicone oil and the like. As the water-soluble polymer, those exemplified as the above-mentioned binder can be used, and among these, vidroxyethyl cellulose is particularly preferable. Further, water-soluble polymers such as polyethylene glycol and polyoxyethylene polyoxypropylene block copolymers can also be suitably used. The gingival coating preferably contains the oily component or the water-soluble polymer in an amount of 10 to 50% by weight and a humectant and water in an amount of 20 to 70% by weight.

The oral composition of the present invention has a pH
Is preferably in the range of 5 to 9.5, particularly 6 to 8.

[0024]

In the oral composition of the present invention, the component (c) improves powderiness caused by salt and sodium bicarbonate, and improves the feeling of use.

[0025]

EXAMPLES The present invention will be described below in more detail with reference to examples, but the present invention is not limited to these examples. still,
The average particle size of the granular salt and granular sodium bicarbonate used in the examples was determined by the following measurement method.

[Method of measuring average particle size of granular salt and granular sodium bicarbonate] 1) 50 g of oral composition is placed in a 300 ml beaker of granular salt, 5000 ml (100 times) of saturated saline is poured into the beaker, and the mixture is stirred with a homomixer. Completely suspend the oral composition. Baking soda is only about 1% soluble in saturated saline, but by dissolving it in a large excess of saturated saline, only sodium bicarbonate can be completely dissolved. The granular salt is recovered from the above suspension using a 200-mesh sieve (U.S.A. standard sieve LC584), and washed on the mesh with saturated saline and ethanol. After leaving in an electric dryer (100 ° C) for about 30 minutes,
After collecting the collected granular salt in a petri dish and measuring the weight, meshes of various sizes (35, 45, 60, 80, 120,
(170, 230, 325 mesh), and the weight of the granular salt remaining on each sieve is measured. From this weight distribution, a geometric mean diameter is determined and defined as the mean particle diameter. 2) Granular sodium bicarbonate The measurement is performed in the same manner as in 1) except that a saturated aqueous sodium bicarbonate solution is used in place of the saturated saline solution in the method of 1).

Examples 1 to 17 and Comparative Example 1 Toothpastes were prepared in accordance with the usual methods according to the composition shown in Table 1 below. About each obtained toothpaste, powderiness was evaluated. The results are shown in Table 2 below.

[0028]

[Table 1]

[0029]

[Table 2]

[0030]

The oral composition of the present invention has an improved feeling of use with improved powderiness caused by salt and sodium bicarbonate.

Claims (3)

(57) [Claims] 1. It contains the following component (a), component (b) and component (c), and the content of component (a) is 10 to 30.
% By weight, the weight ratio of the components (a) and (b)
(Or salt / baking soda) in the range of 1 / 0.5 to 1/3 . (A) Salt (b) Baking soda (c) Basil, camphor, caraway, cardamom, coriander, ginger, laurel, lavender, nutmeg, pepper, thyme, ylang-ylang, carrot seed, elemi, osmantas essential oil and extract, borneol And at least one member selected from the group consisting of and borneol derivatives 2. The method according to claim 1, wherein the component (a) has an average particle size of 150 to 45.
0 μm granular salt, and the component (b) has an average particle size of 4
The oral composition according to claim 1, which is granular sodium bicarbonate having a diameter of 5 to 450 µm. 3. The content of the component (c) is 0.0000.
The oral composition according to claim 1, wherein the amount is from 0.1 to 0.1% by weight.