JPH08508721A - 超常磁性粒子、その製法及びその用途 - Google Patents
超常磁性粒子、その製法及びその用途Info
- Publication number
- JPH08508721A JPH08508721A JP6520523A JP52052394A JPH08508721A JP H08508721 A JPH08508721 A JP H08508721A JP 6520523 A JP6520523 A JP 6520523A JP 52052394 A JP52052394 A JP 52052394A JP H08508721 A JPH08508721 A JP H08508721A
- Authority
- JP
- Japan
- Prior art keywords
- superparamagnetic
- particles
- group
- magnetic
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/5434—Magnetic particles using magnetic particle immunoreagent carriers which constitute new materials per se
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
- H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
- H01F1/0036—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties showing low dimensional magnetism, i.e. spin rearrangements due to a restriction of dimensions, e.g. showing giant magnetoresistivity
- H01F1/0045—Zero dimensional, e.g. nanoparticles, soft nanoparticles for medical/biological use
- H01F1/0054—Coated nanoparticles, e.g. nanoparticles coated with organic surfactant
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- H—ELECTRICITY
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- H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
- H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
- H01F1/01—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials
- H01F1/03—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity
- H01F1/12—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of soft-magnetic materials
- H01F1/34—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of soft-magnetic materials non-metallic substances, e.g. ferrites
- H01F1/36—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of soft-magnetic materials non-metallic substances, e.g. ferrites in the form of particles
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- H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
- H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
- H01F1/44—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of magnetic liquids, e.g. ferrofluids
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
- H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
- H01F1/44—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of magnetic liquids, e.g. ferrofluids
- H01F1/445—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of magnetic liquids, e.g. ferrofluids the magnetic component being a compound, e.g. Fe3O4
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2446/00—Magnetic particle immunoreagent carriers
- G01N2446/20—Magnetic particle immunoreagent carriers the magnetic material being present in the particle core
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2446/00—Magnetic particle immunoreagent carriers
- G01N2446/80—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids
- G01N2446/84—Polymer coating, e.g. gelatin
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2446/00—Magnetic particle immunoreagent carriers
- G01N2446/80—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids
- G01N2446/86—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids the coating being pre-functionalised for attaching immunoreagents, e.g. aminodextran
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
- G01R33/281—Means for the use of in vitro contrast agents
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Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4309333A DE4309333A1 (de) | 1993-03-17 | 1993-03-17 | Superparamagnetische Teilchen, Verfahren zu ihrer Herstellung und Verwendung derselben |
DE4407338A DE4407338A1 (de) | 1993-03-17 | 1994-03-02 | Superparamagnetische Teilchen und deren Verwendung |
DE4407338.0 | 1994-03-02 | ||
DE4309333.7 | 1994-03-02 | ||
PCT/DE1994/000314 WO1994021240A2 (de) | 1993-03-17 | 1994-03-17 | Superparamagnetische teilchen, verfahren zu ihrer herstellung und verwendung derselben |
Publications (1)
Publication Number | Publication Date |
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JPH08508721A true JPH08508721A (ja) | 1996-09-17 |
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Application Number | Title | Priority Date | Filing Date |
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JP6520523A Pending JPH08508721A (ja) | 1993-03-17 | 1994-03-17 | 超常磁性粒子、その製法及びその用途 |
Country Status (6)
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US (1) | US5916539A (zh-CN) |
EP (1) | EP0689430B1 (zh-CN) |
JP (1) | JPH08508721A (zh-CN) |
AT (1) | ATE156706T1 (zh-CN) |
DE (1) | DE59403734D1 (zh-CN) |
WO (1) | WO1994021240A2 (zh-CN) |
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- 1994-03-17 WO PCT/DE1994/000314 patent/WO1994021240A2/de active IP Right Grant
- 1994-03-17 JP JP6520523A patent/JPH08508721A/ja active Pending
- 1994-03-17 US US08/530,132 patent/US5916539A/en not_active Expired - Fee Related
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JP2000507197A (ja) * | 1996-03-18 | 2000-06-13 | ピルグリム,ヘルベルト | R▲下1▼緩和性を増加した超常磁性体粒子、前記粒子の製造方法およびその使用 |
JP2005511335A (ja) * | 2001-04-13 | 2005-04-28 | コーネル・リサーチ・ファンデーション・インコーポレイテッド | 超常磁性ナノ構造材料 |
JP2006502572A (ja) * | 2002-10-09 | 2006-01-19 | フェロファーマ ゲーエムベーハー フォルシュングスラボア | 安定化超常磁性粒子 |
JP2006042621A (ja) * | 2004-07-30 | 2006-02-16 | Canon Inc | 磁性粒子集合体およびそれを用いた標的核酸の抽出装置および抽出方法 |
WO2006068294A1 (ja) * | 2004-12-24 | 2006-06-29 | Japan Science And Technology Agency | 造影剤 |
JP2006182657A (ja) * | 2004-12-24 | 2006-07-13 | Japan Science & Technology Agency | 造影剤 |
US9149545B2 (en) | 2005-11-02 | 2015-10-06 | General Electric Company | Nanoparticle-based imaging agents for X-ray/computed tomography and methods for making same |
JP2009531296A (ja) * | 2006-02-24 | 2009-09-03 | エイティージェン カンパニー リミテッド | 造影剤、知能型造影剤、同時診断及び治療のための薬物伝達体及び/又はタンパク質分離用磁性ナノ複合体 |
JP2010516782A (ja) * | 2007-01-26 | 2010-05-20 | ゼネラル・エレクトリック・カンパニイ | X線/コンピュータ断層撮影用のナノ粒子系造影剤及びその製造方法 |
Also Published As
Publication number | Publication date |
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ATE156706T1 (de) | 1997-08-15 |
US5916539A (en) | 1999-06-29 |
WO1994021240A3 (de) | 1994-10-13 |
EP0689430A1 (de) | 1996-01-03 |
EP0689430B1 (de) | 1997-08-13 |
DE59403734D1 (de) | 1997-09-18 |
WO1994021240A2 (de) | 1994-09-29 |
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