JPH08503928A - 安定な高濃度のフルオレセイン製剤 - Google Patents

安定な高濃度のフルオレセイン製剤

Info

Publication number
JPH08503928A
JPH08503928A JP6506874A JP50687494A JPH08503928A JP H08503928 A JPH08503928 A JP H08503928A JP 6506874 A JP6506874 A JP 6506874A JP 50687494 A JP50687494 A JP 50687494A JP H08503928 A JPH08503928 A JP H08503928A
Authority
JP
Japan
Prior art keywords
fluorescein
cyclodextrin
solution
hydroxypropyl
μmol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6506874A
Other languages
English (en)
Japanese (ja)
Inventor
ラヨス キス,ギョエルギー
ディーター ヴァッハスムート,エルンスト
Original Assignee
チバ−ガイギー アクチエンゲゼルシャフト
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by チバ−ガイギー アクチエンゲゼルシャフト filed Critical チバ−ガイギー アクチエンゲゼルシャフト
Publication of JPH08503928A publication Critical patent/JPH08503928A/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Nanotechnology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP6506874A 1992-09-10 1993-09-02 安定な高濃度のフルオレセイン製剤 Pending JPH08503928A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP92810695.4 1992-09-10
EP92810695 1992-09-10
PCT/EP1993/002367 WO1994005331A1 (de) 1992-09-10 1993-09-02 Stabile hochkonzentrierte formulierungen von fluoresceinderivaten

Publications (1)

Publication Number Publication Date
JPH08503928A true JPH08503928A (ja) 1996-04-30

Family

ID=8211984

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6506874A Pending JPH08503928A (ja) 1992-09-10 1993-09-02 安定な高濃度のフルオレセイン製剤

Country Status (9)

Country Link
US (1) US5573773A (US20100012521A1-20100121-C00001.png)
EP (1) EP0663838A1 (US20100012521A1-20100121-C00001.png)
JP (1) JPH08503928A (US20100012521A1-20100121-C00001.png)
KR (1) KR950703365A (US20100012521A1-20100121-C00001.png)
AU (1) AU4956193A (US20100012521A1-20100121-C00001.png)
CA (1) CA2143115A1 (US20100012521A1-20100121-C00001.png)
FI (1) FI951092A (US20100012521A1-20100121-C00001.png)
TW (1) TW251236B (US20100012521A1-20100121-C00001.png)
WO (1) WO1994005331A1 (US20100012521A1-20100121-C00001.png)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7390668B2 (en) * 1996-10-30 2008-06-24 Provectus Pharmatech, Inc. Intracorporeal medicaments for photodynamic treatment of disease
US8557298B2 (en) 1998-08-06 2013-10-15 Provectus Pharmatech, Inc. Medicaments for chemotherapeutic treatment of disease
US7026166B2 (en) * 2002-01-22 2006-04-11 Chiron Corporation Fluorogenic dyes
US7704756B2 (en) * 2003-01-21 2010-04-27 Novartis Vaccines And Diagnostics, Inc. Fluorogenic dyes
EP1638508B1 (en) * 2003-06-16 2014-08-13 Solx, Inc. Shunt for the treatment of glaucoma
EP1715799A4 (en) * 2004-01-22 2010-06-02 Solx Inc METHOD FOR TREATING GLAUCOMA

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3346123A1 (de) * 1983-12-21 1985-06-27 Janssen Pharmaceutica, N.V., Beerse Pharmazeutische praeparate von in wasser schwerloeslichen oder instabilen arzneistoffen und verfahren zu ihrer herstellung
FR2611141B1 (fr) * 1987-02-20 1991-02-01 Int Rech Cancer Centre Ensemble ou kit pour utilisation comme agent pour la destruction selective de cellules transformees ou tumorales
US5227372A (en) * 1990-03-07 1993-07-13 Children's Medical Center Corporation Method for retaining ophthalmological agents in ocular tissues

Also Published As

Publication number Publication date
US5573773A (en) 1996-11-12
WO1994005331A1 (de) 1994-03-17
KR950703365A (ko) 1995-09-20
AU4956193A (en) 1994-03-29
TW251236B (US20100012521A1-20100121-C00001.png) 1995-07-11
EP0663838A1 (de) 1995-07-26
FI951092A0 (fi) 1995-03-08
FI951092A (fi) 1995-03-08
CA2143115A1 (en) 1994-03-17

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