JPH07506586A - 新規タキサン誘導体，それらの製造，およびそれらを含む組成物 - Google Patents

新規タキサン誘導体，それらの製造，およびそれらを含む組成物

Info

Publication number
JPH07506586A
JPH07506586A JP5519950A JP51995093A JPH07506586A JP H07506586 A JPH07506586 A JP H07506586A JP 5519950 A JP5519950 A JP 5519950A JP 51995093 A JP51995093 A JP 51995093A JP H07506586 A JPH07506586 A JP H07506586A
Authority
JP
Japan
Prior art keywords
carbon atoms
group
atoms
groups
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5519950A
Other languages
English (en)
Japanese (ja)
Inventor
ブルザ，ジヤン−ドミニク
コメルソン，アラン
Original Assignee
ローン−プーラン・ロレ・ソシエテ・アノニム
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ローン−プーラン・ロレ・ソシエテ・アノニム filed Critical ローン−プーラン・ロレ・ソシエテ・アノニム
Publication of JPH07506586A publication Critical patent/JPH07506586A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
JP5519950A 1992-05-21 1993-05-18 新規タキサン誘導体，それらの製造，およびそれらを含む組成物 Pending JPH07506586A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR92/06177 1992-05-21
FR9206177A FR2691460B1 (fr) 1992-05-21 1992-05-21 Nouveaux derives du taxane, leur preparation et les compositions qui les contiennent.
PCT/FR1993/000477 WO1993023389A1 (fr) 1992-05-21 1993-05-18 Nouveaux derives du taxane, leur preparation et les compositions qui les contiennent

Publications (1)

Publication Number Publication Date
JPH07506586A true JPH07506586A (ja) 1995-07-20

Family

ID=9430017

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5519950A Pending JPH07506586A (ja) 1992-05-21 1993-05-18 新規タキサン誘導体，それらの製造，およびそれらを含む組成物

Country Status (13)

Country Link
EP (1) EP0641334A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH07506586A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR950701629A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU4075893A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2136211A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CZ (1) CZ285294A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI945439A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2691460B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MX9302915A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SK (1) SK139994A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW227560B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1993023389A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA933462B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GEP20043239B (en) 2000-02-02 2004-05-25 Florida State Univ Research Foundation Us C10 Carbonate Substituted Taxanes as Antitumor Agents
AU783422B2 (en) 2000-02-02 2005-10-27 Florida State University Research Foundation, Inc. C10 carbamoyloxy substituted taxanes as antitumor agents
US6649632B2 (en) 2000-02-02 2003-11-18 Fsu Research Foundation, Inc. C10 ester substituted taxanes
PE20050693A1 (es) 2004-02-13 2005-09-27 Univ Florida State Res Found Taxanos sustituidos con esteres de ciclopentilo en c10
US8242166B2 (en) 2008-03-31 2012-08-14 Florida State University Research Foundation, Inc. C(10) ethyl ester and C(10) cyclopropyl ester substituted taxanes
WO2010003533A2 (en) * 2008-06-17 2010-01-14 Institut Pasteur Korea Anti-infective compounds
NZ603828A (en) 2010-05-03 2015-09-25 Teikoku Pharma Usa Inc Non-aqueous taxane pro-emulsion formulations and methods of making and using the same
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
CN105294610B (zh) * 2015-07-16 2017-10-31 中国科学院上海药物研究所 7‑epi‑紫杉烷类化合物的制备方法
CN107021943B (zh) * 2016-02-02 2020-12-29 中国科学院上海药物研究所 一类7-epi-巴卡亭III衍生物，及其制备方法和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4206221A (en) * 1979-01-03 1980-06-03 The United States Of America As Represented By The Secretary Of Agriculture Cephalomannine and its use in treating leukemic tumors
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
US4942184A (en) * 1988-03-07 1990-07-17 The United States Of America As Represented By The Department Of Health And Human Services Water soluble, antineoplastic derivatives of taxol
FR2658513B1 (fr) * 1990-02-21 1994-02-04 Rhone Poulenc Sante Procede de preparation de l'acide cis-beta-phenylglycidique-(2r,3r).

Also Published As

Publication number Publication date
CZ285294A3 (en) 1995-04-12
FR2691460A1 (fr) 1993-11-26
SK139994A3 (en) 1995-07-11
EP0641334A1 (fr) 1995-03-08
AU4075893A (en) 1993-12-13
WO1993023389A1 (fr) 1993-11-25
FR2691460B1 (fr) 1994-07-22
FI945439A0 (fi) 1994-11-18
CA2136211A1 (fr) 1993-11-25
MX9302915A (es) 1993-11-01
FI945439L (fi) 1994-11-18
ZA933462B (en) 1993-12-14
KR950701629A (ko) 1995-04-28
TW227560B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1994-08-01
FI945439A7 (fi) 1994-11-18

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